4AOY
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![BU of 4aoy by Molmil](/molmil-images/mine/4aoy) | Open CtIDH. The complex structures of Isocitrate dehydrogenase from Clostridium thermocellum and Desulfotalea psychrophila, support a new active site locking mechanism | Descriptor: | ISOCITRATE DEHYDROGENASE [NADP] | Authors: | Leiros, H.-K.S, Fedoy, A.-E, Leiros, I, Steen, I.H. | Deposit date: | 2012-03-30 | Release date: | 2012-04-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The complex structures of isocitrate dehydrogenase from Clostridium thermocellum and Desulfotalea psychrophila suggest a new active site locking mechanism. Febs Open Bio, 2, 2012
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4AOV
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![BU of 4aov by Molmil](/molmil-images/mine/4aov) | DpIDH-NADP. The complex structures of Isocitrate dehydrogenase from Clostridium thermocellum and Desulfotalea psychrophila, support a new active site locking mechanism | Descriptor: | ISOCITRATE DEHYDROGENASE [NADP], ISOCITRIC ACID, MAGNESIUM ION, ... | Authors: | Leiros, H.-K.S, Fedoy, A.-E, Leiros, I, Steen, I.H. | Deposit date: | 2012-03-30 | Release date: | 2012-07-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | The Complex Structures of Isocitrate Dehydrogenase from Clostridium Thermocellum and Desulfotalea Psychrophila Suggest a New Active Site Locking Mechanism FEBS Open Bio., 2, 2012
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1O7D
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![BU of 1o7d by Molmil](/molmil-images/mine/1o7d) | The structure of the bovine lysosomal a-mannosidase suggests a novel mechanism for low pH activation | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Heikinheimo, P, Helland, R, Leiros, H.S, Leiros, I, Karlsen, S, Evjen, G, Ravelli, R, Schoehn, G, Ruigrok, R, Tollersrud, O.-K, Mcsweeney, S, Hough, E. | Deposit date: | 2002-10-30 | Release date: | 2003-03-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The Structure of Bovine Lysosomal Alpha-Mannosidase Suggests a Novel Mechanism for Low-Ph Activation J.Mol.Biol., 327, 2003
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2Y8B
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![BU of 2y8b by Molmil](/molmil-images/mine/2y8b) | VIM-7 with Oxidised. Structural and computational investigations of VIM-7: Insights into the substrate specificity of VIM metallo-beta- lactamases | Descriptor: | METALLO-B-LACTAMASE, ZINC ION | Authors: | Saradhi, P, Leiros, H.-K.S, Ahmad, R, Spencer, J, Leiros, I, Walsh, T.R, Sundsfjord, A, Samuelsen, O. | Deposit date: | 2011-02-03 | Release date: | 2011-06-15 | Last modified: | 2011-08-31 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and Computational Investigations of Vim- 7: Insights Into the Substrate Specificity of Vim Metallo-Beta-Lactamases J.Mol.Biol., 411, 2011
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2V28
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![BU of 2v28 by Molmil](/molmil-images/mine/2v28) | Apo structure of the cold active phenylalanine hydroxylase from Colwellia psychrerythraea 34H | Descriptor: | PHENYLALANINE-4-HYDROXYLASE, SULFATE ION | Authors: | Leiros, H.-K.S, Pey, A.L, Innselset, M, Moe, E, Leiros, I, Steen, I.H, Martinez, A. | Deposit date: | 2007-06-04 | Release date: | 2007-06-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of Phenylalanine Hydroxylase from Colwellia Psychrerythraea 34H, a Monomeric Cold Active Enzyme with Local Flexibility Around the Active Site and High Overall Stability. J.Biol.Chem., 282, 2007
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2WHZ
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![BU of 2whz by Molmil](/molmil-images/mine/2whz) | |
2V27
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![BU of 2v27 by Molmil](/molmil-images/mine/2v27) | Structure of the cold active phenylalanine hydroxylase from Colwellia psychrerythraea 34H | Descriptor: | FE (III) ION, PHENYLALANINE HYDROXYLASE, SULFATE ION | Authors: | Leiros, H.-K.S, Pey, A.L, Innselset, M, Moe, E, Leiros, I, Steen, I.H, Martinez, A. | Deposit date: | 2007-06-03 | Release date: | 2007-06-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of Phenylalanine Hydroxylase from Colwellia Psychrerythraea 34H, a Monomeric Cold Active Enzyme with Local Flexibility Around the Active Site and High Overall Stability. J.Biol.Chem., 282, 2007
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2WI0
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![BU of 2wi0 by Molmil](/molmil-images/mine/2wi0) | |
2BHZ
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![BU of 2bhz by Molmil](/molmil-images/mine/2bhz) | Crystal structure of Deinococcus radiodurans maltooligosyltrehalose trehalohydrolase in complex with maltose | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, MAGNESIUM ION, ... | Authors: | Timmins, J, Leiros, H.-K.S, Leonard, G, Leiros, I, McSweeney, S. | Deposit date: | 2005-01-20 | Release date: | 2005-03-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Crystal Structure of Maltooligosyltrehalose Trehalohydrolase from Deinococcus Radiodurans in Complex with Disaccharides J.Mol.Biol., 347, 2005
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2BHU
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![BU of 2bhu by Molmil](/molmil-images/mine/2bhu) | Crystal structure of Deinococcus radiodurans maltooligosyltrehalose trehalohydrolase | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, MALTOOLIGOSYLTREHALOSE TREHALOHYDROLASE, ... | Authors: | Timmins, J, Leiros, H.-K.S, Leonard, G, Leiros, I, McSweeney, S. | Deposit date: | 2005-01-18 | Release date: | 2005-03-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Crystal Structure of Maltooligosyltrehalose Trehalohydrolase from Deinococcus Radiodurans in Complex with Disaccharides J.Mol.Biol., 347, 2005
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2BHY
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![BU of 2bhy by Molmil](/molmil-images/mine/2bhy) | Crystal structure of Deinococcus radiodurans maltooligosyltrehalose trehalohydrolase in complex with trehalose | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, MAGNESIUM ION, ... | Authors: | Timmins, J, Leiros, H.-K.S, Leonard, G, Leiros, I, McSweeney, S. | Deposit date: | 2005-01-20 | Release date: | 2005-03-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal Structure of Maltooligosyltrehalose Trehalohydrolase from Deinococcus Radiodurans in Complex with Disaccharides J.Mol.Biol., 347, 2005
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1UTM
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![BU of 1utm by Molmil](/molmil-images/mine/1utm) | Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements | Descriptor: | 2-PHENYLETHYLAMINE, CALCIUM ION, TRYPSIN I | Authors: | Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O. | Deposit date: | 2003-12-09 | Release date: | 2004-01-09 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements Protein Sci., 13, 2004
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1UTN
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![BU of 1utn by Molmil](/molmil-images/mine/1utn) | Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BENZYLAMINE, CALCIUM ION, ... | Authors: | Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O. | Deposit date: | 2003-12-09 | Release date: | 2004-01-09 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements Protein Sci., 13, 2004
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6FAO
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![BU of 6fao by Molmil](/molmil-images/mine/6fao) | Discovery and characterization of a thermostable GH6 endoglucanase from a compost metagenome | Descriptor: | 1,2-ETHANEDIOL, Glycoside hydrolase family 6, SULFATE ION | Authors: | Jensen, M.S, Fredriksen, L, MacKenzie, A.K, Pope, P.B, Chylenski, P, Leiros, I, Williamson, A.K, Christopeit, T, Ostby, H, Vaaje-Kolstad, G, Eijsink, V.G.H. | Deposit date: | 2017-12-15 | Release date: | 2018-06-06 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Discovery and characterization of a thermostable two-domain GH6 endoglucanase from a compost metagenome. PLoS ONE, 13, 2018
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6F9M
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![BU of 6f9m by Molmil](/molmil-images/mine/6f9m) | The LIPY/F-motif in an intracellular subtilisin protease is involved in inhibition | Descriptor: | ACETATE ION, SODIUM ION, Serine protease, ... | Authors: | Bjerga, G.E.K, Larsen, O, Arsin, H, Williamson, A.K, Garcia-Moyano, A, Leiros, I, Puntervoll, P. | Deposit date: | 2017-12-14 | Release date: | 2018-06-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.298 Å) | Cite: | Mutational analysis of the pro-peptide of a marine intracellular subtilisin protease supports its role in inhibition. Proteins, 86, 2018
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1UTO
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![BU of 1uto by Molmil](/molmil-images/mine/1uto) | Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements | Descriptor: | 2-PHENYLETHYLAMINE, CALCIUM ION, GLYCEROL, ... | Authors: | Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O. | Deposit date: | 2003-12-09 | Release date: | 2004-01-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements Protein Sci., 13, 2004
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1UTK
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![BU of 1utk by Molmil](/molmil-images/mine/1utk) | Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements | Descriptor: | CALCIUM ION, SULFATE ION, TRYPSIN I | Authors: | Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O. | Deposit date: | 2003-12-09 | Release date: | 2004-01-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements Protein Sci., 13, 2004
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1UTP
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![BU of 1utp by Molmil](/molmil-images/mine/1utp) | Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements | Descriptor: | 4-PHENYLBUTYLAMINE, CALCIUM ION, GLYCEROL, ... | Authors: | Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O. | Deposit date: | 2003-12-09 | Release date: | 2004-01-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements Protein Sci., 13, 2004
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1UTQ
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![BU of 1utq by Molmil](/molmil-images/mine/1utq) | Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements | Descriptor: | CALCIUM ION, GLYCEROL, TRYPSINOGEN | Authors: | Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O. | Deposit date: | 2003-12-09 | Release date: | 2004-01-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements Protein Sci., 13, 2004
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1UTL
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![BU of 1utl by Molmil](/molmil-images/mine/1utl) | Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-PHENYLPROPYLAMINE, CALCIUM ION, ... | Authors: | Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O. | Deposit date: | 2003-12-09 | Release date: | 2004-01-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements Protein Sci., 13, 2004
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1UTJ
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![BU of 1utj by Molmil](/molmil-images/mine/1utj) | Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements | Descriptor: | BENZYLAMINE, CALCIUM ION, TRYPSIN I | Authors: | Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O. | Deposit date: | 2003-12-09 | Release date: | 2004-01-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements Protein Sci., 13, 2004
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2YG8
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![BU of 2yg8 by Molmil](/molmil-images/mine/2yg8) | Structure of an unusual 3-Methyladenine DNA Glycosylase II (Alka) from Deinococcus radiodurans | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, DNA-3-methyladenine glycosidase II, ... | Authors: | Moe, E, Hall, D.R, Leiros, I, Talstad, V, Timmins, J, McSweeney, S. | Deposit date: | 2011-04-11 | Release date: | 2011-04-20 | Last modified: | 2018-12-05 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-function studies of an unusual 3-methyladenine DNA glycosylase II (AlkA) from Deinococcus radiodurans. Acta Crystallogr. D Biol. Crystallogr., 68, 2012
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2YG9
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![BU of 2yg9 by Molmil](/molmil-images/mine/2yg9) | Structure of an unusual 3-Methyladenine DNA Glycosylase II (Alka) from Deinococcus radiodurans | Descriptor: | CHLORIDE ION, DNA-3-methyladenine glycosidase II, putative, ... | Authors: | Moe, E, Hall, D.R, Leiros, I, Talstad, V, Timmins, J, McSweeney, S. | Deposit date: | 2011-04-11 | Release date: | 2011-04-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure-function studies of an unusual 3-methyladenine DNA glycosylase II (AlkA) from Deinococcus radiodurans. Acta Crystallogr. D Biol. Crystallogr., 68, 2012
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2IV0
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![BU of 2iv0 by Molmil](/molmil-images/mine/2iv0) | Thermal stability of isocitrate dehydrogenase from Archaeoglobus fulgidus studied by crystal structure analysis and engineering of chimers | Descriptor: | CHLORIDE ION, ISOCITRATE DEHYDROGENASE, ZINC ION | Authors: | Stokke, R, Karlstrom, M, Yang, N, Leiros, I, Ladenstein, R, Birkeland, N.K, Steen, I.H. | Deposit date: | 2006-06-08 | Release date: | 2007-04-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Thermal Stability of Isocitrate Dehydrogenase from Archaeoglobus Fulgidus Studied by Crystal Structure Analysis and Engineering of Chimers Extremophiles, 11, 2007
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2J0V
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![BU of 2j0v by Molmil](/molmil-images/mine/2j0v) | The crystal structure of Arabidopsis thaliana RAC7-ROP9: the first RAS superfamily GTPase from the plant kingdom | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAC-LIKE GTP-BINDING PROTEIN ARAC7 | Authors: | Sormo, C.G, Leiros, I, Brembu, T, Winge, P, Os, V, Bones, A.M. | Deposit date: | 2006-08-07 | Release date: | 2006-10-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | The Crystal Structure of Arabidopsis Thaliana Rac7/Rop9: The First Ras Superfamily Gtpase from the Plant Kingdom. Phytochemistry, 67, 2006
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