7B07
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![BU of 7b07 by Molmil](/molmil-images/mine/7b07) | TgoT_6G12 apo | 分子名称: | CALCIUM ION, DNA polymerase | 著者 | Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M. | 登録日 | 2020-11-18 | 公開日 | 2020-12-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.099 Å) | 主引用文献 | Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution. Biomolecules, 10, 2020
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8B8A
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![BU of 8b8a by Molmil](/molmil-images/mine/8b8a) | Multimerization domain of borna disease virus 1 phosphoprotein | 分子名称: | Phosphoprotein | 著者 | Tarbouriech, N, Legrand, P, Bourhis, J.M, Chenavier, F, Freslon, L, Kawasaki, J, Horie, M, Tomonaga, K, Bachiri, K, Coyaud, E, Gonzalez-Dunia, D, Ruigrok, R.W.H, Crepin, T. | 登録日 | 2022-10-04 | 公開日 | 2022-11-23 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Borna Disease Virus 1 Phosphoprotein Forms a Tetramer and Interacts with Host Factors Involved in DNA Double-Strand Break Repair and mRNA Processing. Viruses, 14, 2022
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6F2A
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![BU of 6f2a by Molmil](/molmil-images/mine/6f2a) | Crystal structure of the complex Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO1 with Fe(II)/Lysine | 分子名称: | ACETIC ACID, CHLORIDE ION, FE (II) ION, ... | 著者 | Isabet, T, Stura, E.A, Legrand, P, Zaparucha, A, Bastard, K. | 登録日 | 2017-11-24 | 公開日 | 2018-11-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family. Sci Rep, 8, 2018
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6F2B
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![BU of 6f2b by Molmil](/molmil-images/mine/6f2b) | Crystal structure of the complex Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO1 with Fe(II)/alpha-ketoglutarate | 分子名称: | 2-OXOGLUTARIC ACID, FE (II) ION, L-lysine 3-hydroxylase | 著者 | Isabet, T, Stura, E.A, Legrand, P, Zaparucha, A, Bastard, K. | 登録日 | 2017-11-24 | 公開日 | 2018-11-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family. Sci Rep, 8, 2018
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6EXF
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![BU of 6exf by Molmil](/molmil-images/mine/6exf) | Crystal structure of the complex Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO5 with Fe(II)/Lysine | 分子名称: | FE (III) ION, GLYCEROL, L-lysine 4-hydroxylase, ... | 著者 | Isabet, T, Stura, E, Legrand, P, Zaparucha, A, Bastard, K. | 登録日 | 2017-11-08 | 公開日 | 2018-11-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family. Sci Rep, 8, 2018
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6F9P
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![BU of 6f9p by Molmil](/molmil-images/mine/6f9p) | Crystal structure of the Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO5 with Re(II) | 分子名称: | CHLORIDE ION, GLYCEROL, L-lysine 4-hydroxylase, ... | 著者 | Isabet, T, Stura, E, Legrand, P, Zaparucha, A, Bastard, K. | 登録日 | 2017-12-15 | 公開日 | 2018-11-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family. Sci Rep, 8, 2018
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8AUC
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![BU of 8auc by Molmil](/molmil-images/mine/8auc) | Structure of peptidoglycan hydrolase Cg1735 from Corynebacterium glutamicum, trigonal crystal form | 分子名称: | Cell wall-associated hydrolases (Invasion-associated proteins), TETRACHLOROPLATINATE(II) | 著者 | Gaday, Q, Wehenkel, A.M, Alzari, P.M, Legrand, P. | 登録日 | 2022-08-25 | 公開日 | 2023-01-18 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | FtsEX-independent control of RipA-mediated cell separation in Corynebacteriales. Proc.Natl.Acad.Sci.USA, 119, 2022
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6EXH
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![BU of 6exh by Molmil](/molmil-images/mine/6exh) | Crystal structure of the complex Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO5 with Fe(II)/succinate/(4R)-4-hydroxy-L-lysine | 分子名称: | 4-HYDROXY-LYSINE, FE (III) ION, GLYCEROL, ... | 著者 | Isabet, T, Stura, E, Legrand, P, Zaparucha, A, Bastard, K. | 登録日 | 2017-11-08 | 公開日 | 2018-11-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family. Sci Rep, 8, 2018
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6EUO
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![BU of 6euo by Molmil](/molmil-images/mine/6euo) | Crystal structure of APO Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO5 | 分子名称: | D-MALATE, FE (III) ION, GLYCEROL, ... | 著者 | Isabet, T, Stura, E, Legrand, P, Zaparucha, A, Bastard, K. | 登録日 | 2017-10-30 | 公開日 | 2018-11-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family. Sci Rep, 8, 2018
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6EUR
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![BU of 6eur by Molmil](/molmil-images/mine/6eur) | Crystal structure of the complex Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO5 with Fe(II)/alpha-ketoglutarate | 分子名称: | 2-OXOGLUTARIC ACID, FE (III) ION, GLYCEROL, ... | 著者 | Isabet, T, Stura, E, Legrand, P, Zaparucha, A, Bastard, K. | 登録日 | 2017-10-31 | 公開日 | 2018-11-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family. Sci Rep, 8, 2018
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6F6J
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![BU of 6f6j by Molmil](/molmil-images/mine/6f6j) | Crystal structure of the Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO1 with Fe(II)/succinate/(3S)-3-hydroxy-L-lysine | 分子名称: | (2~{S},3~{R})-2,6-bis(azanyl)-3-oxidanyl-hexanoic acid, ACETATE ION, FE (III) ION, ... | 著者 | Isabet, T, Stura, E.A, Legrand, P, Zaparucha, A, Bastard, K. | 登録日 | 2017-12-05 | 公開日 | 2018-11-14 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family. Sci Rep, 8, 2018
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8B8D
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![BU of 8b8d by Molmil](/molmil-images/mine/8b8d) | multimerization domain of Gaboon Viper Virus 1 | 分子名称: | Phosphoprotein | 著者 | Tarbouriech, N, Legrand, P, Bouhris, J.M, Horie, M, Tomonaga, K, Crepin, T. | 登録日 | 2022-10-04 | 公開日 | 2022-11-23 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Borna Disease Virus 1 Phosphoprotein Forms a Tetramer and Interacts with Host Factors Involved in DNA Double-Strand Break Repair and mRNA Processing. Viruses, 14, 2022
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6ZP9
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![BU of 6zp9 by Molmil](/molmil-images/mine/6zp9) | |
8A51
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![BU of 8a51 by Molmil](/molmil-images/mine/8a51) | Crystal structure of HSF2BP-BRME1 complex | 分子名称: | 1,2-ETHANEDIOL, Break repair meiotic recombinase recruitment factor 1, CHLORIDE ION, ... | 著者 | Miron, S, Legrand, P, Ropars, V, Ghouil, R, Zinn-Justin, S. | 登録日 | 2022-06-13 | 公開日 | 2023-07-05 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | BRCA2-HSF2BP oligomeric ring disassembly by BRME1 promotes homologous recombination. Sci Adv, 9, 2023
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8BV1
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![BU of 8bv1 by Molmil](/molmil-images/mine/8bv1) | Peptide inhibitor P4 in complex with ASF1 histone chaperone | 分子名称: | GLYCEROL, Histone chaperone ASF1A, P4 peptide inhibitor of histone chaperone ASF1 | 著者 | Perrin, M.E, Li, B, Mbianda, J, Ropars, V, Legrand, P, Douat, C, Ochsenbein, F, Guichard, G. | 登録日 | 2022-12-01 | 公開日 | 2023-07-05 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.834 Å) | 主引用文献 | Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach. Chem.Commun.(Camb.), 59, 2023
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7ANQ
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![BU of 7anq by Molmil](/molmil-images/mine/7anq) | Complete PCSK9 C-ter domain in complex with VHH P1.40 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Proprotein convertase subtilisin/kexin type 9, SULFATE ION, ... | 著者 | Ciccone, L, Legrand, P, Stura, E.A, Dive, V, Seidahn, N.G, Fruchart Gaillard, C. | 登録日 | 2020-10-12 | 公開日 | 2021-10-20 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Molecular interactions of PCSK9 with an inhibitory nanobody, CAP1 and HLA-C: Functional regulation of LDLR levels. Mol Metab, 67, 2022
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6T1Z
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![BU of 6t1z by Molmil](/molmil-images/mine/6t1z) | LmrP from L. lactis, in an outward-open conformation, bound to Hoechst 33342 | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DODECYL-ALPHA-D-MALTOSIDE, ... | 著者 | Hutchin, A, Debruycker, V, Masureel, M, Legrand, P, Remaut, H, Govaerts, C. | 登録日 | 2019-10-07 | 公開日 | 2020-07-29 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity. Nat.Struct.Mol.Biol., 27, 2020
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6F2E
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![BU of 6f2e by Molmil](/molmil-images/mine/6f2e) | Crystal structure of the APO Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO1 | 分子名称: | ACETIC ACID, L-lysine 3-hydroxylase | 著者 | Isabet, T, Stura, E.A, Legrand, P, Zaparucha, A, Bastard, K. | 登録日 | 2017-11-24 | 公開日 | 2018-11-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family. Sci Rep, 8, 2018
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6ZPA
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![BU of 6zpa by Molmil](/molmil-images/mine/6zpa) | Cyanophage S-2L HD phosphohydrolase (DatZ) bound to dA and one catalytic Zn2+ ion | 分子名称: | (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, DatZ, LITHIUM ION, ... | 著者 | Czernecki, D, Legrand, P, Delarue, M. | 登録日 | 2020-07-08 | 公開日 | 2021-03-03 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (0.86000258 Å) | 主引用文献 | How cyanophage S-2L rejects adenine and incorporates 2-aminoadenine to saturate hydrogen bonding in its DNA. Nat Commun, 12, 2021
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6ZPC
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![BU of 6zpc by Molmil](/molmil-images/mine/6zpc) | Cyanophage S-2L HD phosphohydrolase (DatZ) bound to dATP | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DatZ, LITHIUM ION, ... | 著者 | Czernecki, D, Legrand, P, Delarue, M. | 登録日 | 2020-07-08 | 公開日 | 2021-03-03 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.2683593 Å) | 主引用文献 | How cyanophage S-2L rejects adenine and incorporates 2-aminoadenine to saturate hydrogen bonding in its DNA. Nat Commun, 12, 2021
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6ZPB
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![BU of 6zpb by Molmil](/molmil-images/mine/6zpb) | Cyanophage S-2L HD phosphohydrolase (DatZ) bound to dA and two catalytic Co2+ ions | 分子名称: | (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, COBALT (II) ION, DatZ | 著者 | Czernecki, D, Legrand, P, Delarue, M. | 登録日 | 2020-07-08 | 公開日 | 2021-03-03 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.72097385 Å) | 主引用文献 | How cyanophage S-2L rejects adenine and incorporates 2-aminoadenine to saturate hydrogen bonding in its DNA. Nat Commun, 12, 2021
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6ZUF
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![BU of 6zuf by Molmil](/molmil-images/mine/6zuf) | Urea-based Foldamer Inhibitor chimera C2 in complex with ASF1 Histone chaperone | 分子名称: | C2 foldamer/peptide hybrid inhibitor of histone chaperone ASF1, GLYCEROL, Histone chaperone ASF1A, ... | 著者 | Bakail, M, Mbianda, J, Perrin, E.M, Guerois, R, Legrand, P, Traore, S, Douat, C, Guichard, G, Ochsenbein, F. | 登録日 | 2020-07-22 | 公開日 | 2021-06-09 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.798 Å) | 主引用文献 | Optimal anchoring of a foldamer inhibitor of ASF1 histone chaperone through backbone plasticity. Sci Adv, 7, 2021
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7AWP
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![BU of 7awp by Molmil](/molmil-images/mine/7awp) | Structure of the thermostabilized EAAT1 cryst-II mutant in complex with rubidium and barium ions and the allosteric inhibitor UCPH101 | 分子名称: | 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, BARIUM ION, Excitatory amino acid transporter 1,Neutral amino acid transporter B(0),Excitatory amino acid transporter 1, ... | 著者 | Canul-Tec, J.C, Legrand, P, Reyes, N. | 登録日 | 2020-11-08 | 公開日 | 2021-10-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.91 Å) | 主引用文献 | The ion-coupling mechanism of human excitatory amino acid transporters. Embo J., 41, 2022
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7AWM
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![BU of 7awm by Molmil](/molmil-images/mine/7awm) | Structure of the thermostabilized EAAT1 cryst mutant in complex with L-ASP, three sodium ions and the allosteric inhibitor UCPH101 | 分子名称: | 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, ASPARTIC ACID, BARIUM ION, ... | 著者 | Canul-Tec, J.C, Legrand, P, Reyes, N. | 登録日 | 2020-11-08 | 公開日 | 2021-10-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | The ion-coupling mechanism of human excitatory amino acid transporters. Embo J., 41, 2022
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7AWL
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![BU of 7awl by Molmil](/molmil-images/mine/7awl) | Structure of the thermostabilized EAAT1 cryst-II mutant in complex with barium and the allosteric inhibitor UCPH101 | 分子名称: | 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, BARIUM ION, Excitatory amino acid transporter 1, ... | 著者 | Canul-Tec, J.C, Legrand, P, Reyes, N. | 登録日 | 2020-11-08 | 公開日 | 2021-10-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | The ion-coupling mechanism of human excitatory amino acid transporters. Embo J., 41, 2022
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