4PGX
 
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4NLN
 | | Structure of human DNA polymerase beta complexed with nicked DNA containing a template 8BrG and incoming CTP | | 分子名称: | 5'-D(*CP*CP*GP*AP*CP*(BGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | | 著者 | Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. | | 登録日 | 2013-11-14 | | 公開日 | 2014-01-22 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.261 Å) | | 主引用文献 | Structural basis for promutagenicity of 8-halogenated Guanine.
J.Biol.Chem., 289, 2014
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4NLZ
 | | Structure of human DNA polymerase beta complexed with nicked DNA containing a mismatched template 8BrG and incoming GTP | | 分子名称: | 5'-D(*CP*CP*GP*AP*CP*(BGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*AP*G)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | | 著者 | Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. | | 登録日 | 2013-11-14 | | 公開日 | 2014-01-22 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.683 Å) | | 主引用文献 | Structural basis for promutagenicity of 8-halogenated Guanine.
J.Biol.Chem., 289, 2014
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2Z99
 | | Crystal Structure of ScpB from Mycobacterium tuberculosis | | 分子名称: | Putative uncharacterized protein | | 著者 | Kim, J.-S, Lee, S, Kang, B.S, Kim, M.H, Lee, H.-S, Kim, K.J. | | 登録日 | 2007-09-18 | | 公開日 | 2007-10-09 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure and domain characterization of ScpB from Mycobacterium tuberculosis
Proteins, 71, 2008
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4OFA
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4FES
 | | Structure of OSH4 in complex with cholesterol analogs | | 分子名称: | (3S,8S,9S,10R,13S,14S,17R)-3-hydroxy-10,13-dimethyl-17-[(2S,6S)-6-methyl-3-oxooctan-2-yl]-1,2,3,4,7,8,9,10,11,12,13,14,15,17-tetradecahydro-16H-cyclopenta[a]phenanthren-16-one, Protein KES1 | | 著者 | Koag, M.C, Monzingo, A.F, Cheun, Y, Lee, S. | | 登録日 | 2012-05-30 | | 公開日 | 2013-06-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Synthesis and structure of 16,22-diketocholesterol bound to oxysterol-binding protein Osh4.
Steroids, 78, 2013
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4PGY
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4FCW
 | | Crystal structure of the C-terminal domain of ClpB | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB | | 著者 | Biter, A.B, Lee, S, Sung, N, Tsai, F.T.F. | | 登録日 | 2012-05-25 | | 公開日 | 2012-07-18 | | 最終更新日 | 2018-04-18 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural basis for intersubunit signaling in a protein disaggregating machine.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4NM1
 | | Structure of human DNA polymerase beta complexed with a nicked DNA containing a 8BrG-C at N-1 position and G-C at N position | | 分子名称: | 5'-D(*CP*CP*GP*AP*CP*GP*(BGM)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | | 著者 | Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. | | 登録日 | 2013-11-14 | | 公開日 | 2014-01-22 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.415 Å) | | 主引用文献 | Structural basis for promutagenicity of 8-halogenated Guanine.
J.Biol.Chem., 289, 2014
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4PHE
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4PHA
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4FCT
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4FD2
 | | Crystal structure of the C-terminal domain of ClpB | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB | | 著者 | Biter, A.B, Lee, S, Sung, N, Tsai, F.T.F. | | 登録日 | 2012-05-25 | | 公開日 | 2012-07-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis for intersubunit signaling in a protein disaggregating machine.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4PH5
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4PHD
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4JCH
 | | OSH4 bound to an electrophilic oxysterol | | 分子名称: | (3beta,9beta,22R,25R)-3-hydroxyfurost-5-en-27-yl propanoate, Protein KES1 | | 著者 | Koag, M.C, Kou, Y.I, Monzingo, A.F, Lee, S. | | 登録日 | 2013-02-21 | | 公開日 | 2014-03-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of OSH4 bound to an electrophilic oxysterol
To be Published
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5HHH
 | | Structure of human DNA polymerase beta Host-Guest complexed with the control G for N7-CBZ-platination | | 分子名称: | DNA (5'-D(*CP*CP*GP*AP*CP*GP*GP*AP*GP*GP*AP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*TP*CP*CP*TP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... | | 著者 | Koag, M.-C, Lee, S. | | 登録日 | 2016-01-11 | | 公開日 | 2017-01-18 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.363 Å) | | 主引用文献 | Synthesis, structure, and biological evaluation of a platinum-carbazole conjugate.
Chem Biol Drug Des, 91, 2018
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7FDC
 | | CryoEM Structures of Reconstituted V-ATPase, state3 | | 分子名称: | Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | | 著者 | Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H. | | 登録日 | 2021-07-16 | | 公開日 | 2021-12-22 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | | 主引用文献 | CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021
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7FDA
 | | CryoEM Structure of Reconstituted V-ATPase, state1 | | 分子名称: | Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | | 著者 | Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H. | | 登録日 | 2021-07-16 | | 公開日 | 2021-12-22 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021
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4M47
 | | structure of human DNA polymerase complexed with 8-BrG in the template base paired with incoming non-hydrolyzable GTP | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA polymerase beta, MAGNESIUM ION, ... | | 著者 | Koag, M.C, Min, K, Monzingo, A.F, Lee, S. | | 登録日 | 2013-08-06 | | 公開日 | 2014-01-22 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Structural basis for promutagenicity of 8-halogenated Guanine.
J.Biol.Chem., 289, 2014
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7FDB
 | | CryoEM Structures of Reconstituted V-ATPase,State2 | | 分子名称: | Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | | 著者 | Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H. | | 登録日 | 2021-07-16 | | 公開日 | 2021-12-22 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021
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7FDE
 | | CryoEM Structures of Reconstituted V-ATPase, Oxr1 bound V1 | | 分子名称: | Oxidation resistance protein 1, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | | 著者 | Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H. | | 登録日 | 2021-07-16 | | 公開日 | 2021-12-29 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021
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4MF2
 | | Structure of human DNA polymerase beta complexed with O6MG as the template base in a 1-nucleotide gapped DNA | | 分子名称: | DNA polymerase beta, SODIUM ION, synthetic downstream primer, ... | | 著者 | Koag, M.C, Min, K, Monzingo, A.F, Lee, S. | | 登録日 | 2013-08-27 | | 公開日 | 2014-04-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta.
J.Am.Chem.Soc., 136, 2014
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4MF8
 | | Structure of human DNA polymerase beta complexed with nicked DNA containing a mismatched template O6MG and incoming CTP | | 分子名称: | DNA polymerase beta, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Koag, M.C, Min, K, Monzingo, A.F, Lee, S. | | 登録日 | 2013-08-27 | | 公開日 | 2014-08-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Structures of human DNA polymerase beta inserting bases opposite templating O6MG
To be Published
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4MFF
 | | Structure of human DNA polymerase beta complexed with O6MG in the template base paired with incoming non-hydrolyzable TTP | | 分子名称: | 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA polymerase beta, MAGNESIUM ION, ... | | 著者 | Koag, M.C, Min, K, Monzingo, A.F, Lee, S. | | 登録日 | 2013-08-27 | | 公開日 | 2014-04-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta.
J.Am.Chem.Soc., 136, 2014
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