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PDB: 322 件
3NYJ
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Crystal Structure Analysis of APP E2 domain
分子名称: Amyloid beta A4 protein, OSMIUM ION
著者Ha, Y, Hu, J, Lee, S, Liu, X.
登録日2010-07-15
公開日2011-06-01
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The E2 Domains of APP and APLP1 Share a Conserved Mode of Dimerization.
Biochemistry, 50, 2011
2AG4
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BU of 2ag4 by Molmil
Crystal Structure Analysis of GM2-activator protein complexed with phosphatidylcholine
分子名称: (7R)-4,7-DIHYDROXY-N,N,N-TRIMETHYL-10-OXO-3,5,9-TRIOXA-4-PHOSPHAHEPTACOSAN-1-AMINIUM 4-OXIDE, Ganglioside GM2 activator, ISOPROPYL ALCOHOL, ...
著者Wright, C.S, Mi, L.Z, Lee, S, Rastinejad, F.
登録日2005-07-26
公開日2005-10-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
3OH9
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AlkA Undamaged DNA Complex: Interrogation of a T:A base pair
分子名称: 5'-D(*AP*CP*AP*(BRU)P*GP*AP*AP*(BRU)P*GP*CP*C)-3', 5'-D(*GP*GP*CP*AP*TP*TP*CP*AP*TP*GP*T)-3', DNA-3-methyladenine glycosylase 2
著者Bowman, B.R, Lee, S, Wang, S, Verdine, G.L.
登録日2010-08-17
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.802 Å)
主引用文献Structure of Escherichia coli AlkA in Complex with Undamaged DNA.
J.Biol.Chem., 285, 2010
2SNW
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BU of 2snw by Molmil
SINDBIS VIRUS CAPSID PROTEIN, TYPE3 CRYSTAL FORM
分子名称: COAT PROTEIN C
著者Choi, H.-K, Lee, S, Zhang, Y.-P, Mckinney, B.R, Wengler, G, Rossmann, M.G, Kuhn, R.J.
登録日1998-02-17
公開日1998-04-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis.
J.Mol.Biol., 262, 1996
5IS1
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BU of 5is1 by Molmil
Crystal structure of the extracellular domain of sensor histidine kinase YycG from Staphylococcus aureus at 2.0 Angstrom resolution
分子名称: Histidine kinase
著者Kim, T, Choi, J, Lee, S, Kim, K.K.
登録日2016-03-15
公開日2016-07-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献Structural Studies on the Extracellular Domain of Sensor Histidine Kinase YycG from Staphylococcus aureus and Its Functional Implications
J.Mol.Biol., 428, 2016
5I3D
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BU of 5i3d by Molmil
Sulfolobus solfataricus beta-glycosidase - E387Y mutant
分子名称: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ACETATE ION, Beta-galactosidase
著者Iglesias-Fernandez, J, Hancock, S.M, Lee, S.S, McAuley, K.E, Fordham-Skelton, A, Rovira, C, Davis, B.D.
登録日2016-02-10
公開日2017-02-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献A front-face 'SNi synthase' engineered from a retaining 'double-SN2' hydrolase.
Nat. Chem. Biol., 13, 2017
3OH6
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AlkA Undamaged DNA Complex: Interrogation of a C:G base pair
分子名称: 5'-D(*GP*AP*CP*AP*(BRU)P*GP*AP*AP*(BRU)P*GP*CP*C)-3', 5'-D(*GP*CP*AP*TP*TP*CP*AP*TP*GP*TP*C)-3', DNA-3-methyladenine glycosylase 2
著者Bowman, B.R, Lee, S, Wang, S, Verdine, G.L.
登録日2010-08-17
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.894 Å)
主引用文献Structure of Escherichia coli AlkA in Complex with Undamaged DNA.
J.Biol.Chem., 285, 2010
7C11
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Formate--tetrahydrofolate ligase from Methylobacterium extorquens CM4 strain
分子名称: ACETATE ION, CITRATE ANION, Formate-tetrahydrofolate ligase, ...
著者Kim, K.-J, Kim, S, Seo, H, Lee, S.
登録日2020-05-02
公開日2020-10-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.815 Å)
主引用文献Biochemical properties and crystal structure of formate-tetrahydrofolate ligase from Methylobacterium extorquens CM4.
Biochem.Biophys.Res.Commun., 528, 2020
7FD4
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A complete three-dimensional structure of the Lon protease translocating a protein substrate (conformation 1)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Lon protease, ...
著者Li, S, Hsieh, K, Kuo, C, Lee, S, Pintilie, G, Zhang, K, Chang, C.
登録日2021-07-16
公開日2021-11-03
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Complete three-dimensional structures of the Lon protease translocating a protein substrate.
Sci Adv, 7, 2021
7FD5
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A complete three-dimensional structure of the Lon protease translocating a protein substrate (conformation 2)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Lon protease, ...
著者Li, S, Hsieh, K, Kuo, C, Lee, S, Pintilie, G, Zhang, K, Chang, C.
登録日2021-07-16
公開日2021-11-03
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Complete three-dimensional structures of the Lon protease translocating a protein substrate.
Sci Adv, 7, 2021
3OGD
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AlkA Undamaged DNA Complex: Interrogation of a G*:C base pair
分子名称: 5'-D(*CP*AP*(BRU)P*GP*AP*CP*(BRU)P*GP*C)-3', 5'-D(*GP*CP*AP*GP*TP*CP*AP*TP*G)-3', DNA-3-methyladenine glycosylase 2
著者Bowman, B.R, Lee, S, Wang, S, Verdine, G.L.
登録日2010-08-16
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of Escherichia coli AlkA in Complex with Undamaged DNA.
J.Biol.Chem., 285, 2010
1YD8
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BU of 1yd8 by Molmil
COMPLEX OF HUMAN GGA3 GAT DOMAIN AND UBIQUITIN
分子名称: ADP-RIBOSYLATION FACTOR BINDING PROTEIN GGA3, UBIQUIN
著者Prag, G, Lee, S, Mattera, R, Arighi, C.N, Beach, B.M, Bonifacino, J.S, Hurley, J.H.
登録日2004-12-23
公開日2005-02-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural mechanism for ubiquitinated-cargo recognition by the Golgi-localized, {gamma}-ear-containing, ADP-ribosylation-factor-binding proteins
Proc.Natl.Acad.Sci.USA, 102, 2005
4NM2
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BU of 4nm2 by Molmil
Structure of human DNA polymerase beta complexed with a nicked DNA containing a 8BrG-G at N-1 position and G-C at N position
分子名称: 5'-D(*CP*CP*GP*AP*CP*GP*(BGM)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*GP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ...
著者Koag, M.-C, Min, K, Monzingo, A.F, Lee, S.
登録日2013-11-14
公開日2014-01-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.524 Å)
主引用文献Structural basis for promutagenicity of 8-halogenated Guanine.
J.Biol.Chem., 289, 2014
4NLK
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Structure of human DNA polymerase beta complexed with 8BrG in the template base-paired with incoming non-hydrolyzable CTP
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, 5'-D(*CP*CP*GP*AP*CP*(BGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', ...
著者Koag, M.-C, Min, K, Monzingo, A.F, Lee, S.
登録日2013-11-14
公開日2014-01-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.494 Å)
主引用文献Structural basis for promutagenicity of 8-halogenated Guanine.
J.Biol.Chem., 289, 2014
4NXZ
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BU of 4nxz by Molmil
DNA polymerase beta with O6mG in the template base opposite to incoming non-hydrolyzable TTP with manganese in the active site
分子名称: 5'-D(*CP*CP*GP*AP*CP*(6OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ...
著者Koag, M.-C, Min, K, Monzingo, A.F, Lee, S.
登録日2013-12-09
公開日2014-04-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.557 Å)
主引用文献Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta.
J.Am.Chem.Soc., 136, 2014
4NY8
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BU of 4ny8 by Molmil
DNA polymerase beta with O6mG in the template base opposite to incoming non-hydrolyzable CTP with manganese in the active site
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, 5'-D(*CP*CP*GP*AP*CP*(6OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', ...
著者Koag, M.-C, Min, K, Monzingo, A.F, Lee, S.
登録日2013-12-10
公開日2014-04-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.246 Å)
主引用文献Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta.
J.Am.Chem.Soc., 136, 2014
4F4B
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Structure of OSH4 with a cholesterol analog
分子名称: (3beta,9beta,25R)-3-hydroxy-26-iodocholest-5-ene-16,22-dione, Protein KES1
著者Koag, M.C, Monzingo, A.F, Cheun, Y, Lee, S.
登録日2012-05-10
公開日2013-05-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Synthesis and structure of 16,22-diketocholesterol bound to oxysterol-binding protein Osh4.
Steroids, 78, 2013
4O5E
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BU of 4o5e by Molmil
Structure of human DNA polymerase complexed with N7MG in the template base paired with incoming non-hydrolyzable TTP
分子名称: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*CP*CP*GP*AP*CP*(FMG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
著者Koag, M.C, Lee, S.
登録日2013-12-19
公開日2014-07-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.532 Å)
主引用文献Transition-state destabilization reveals how human DNA polymerase beta proceeds across the chemically unstable lesion N7-methylguanine.
Nucleic Acids Res., 42, 2014
4O5K
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Structure of human DNA polymerase complexed with N7MG in the template base paired with incoming non-hydrolyzable CTP
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*(FMG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
著者Koag, M.C, Lee, S.
登録日2013-12-19
公開日2014-07-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.058 Å)
主引用文献Transition-state destabilization reveals how human DNA polymerase beta proceeds across the chemically unstable lesion N7-methylguanine.
Nucleic Acids Res., 42, 2014
4OFH
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Structural basis for thymine glycosylase activity on T:O6-methylG mismatch by methyl-CpG binding domain protein 4: Implications for roles of Arg468 in mismatch recognition and catalysis
分子名称: 12-mer DNA(O6MeG), 12-mer DNA(T), MAGNESIUM ION, ...
著者Ouzon-Shubeita, H, Lin, Y.-L, Lee, S.
登録日2014-01-14
公開日2015-04-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structure of MBD4 bound to O6MeG:T mispair DNA
To be Published
4OFE
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Structural basis for thymine glycosylase activity on T:O6-methylG mismatch by methyl-CpG binding domain protein 4: Implications for roles of Arg468 in mismatch recognition and catalysis
分子名称: 12-mer DNA(G), 12-mer DNA(T), MAGNESIUM ION, ...
著者Ouzon-Shubeita, H, Lin, Y.-L, Lee, S.
登録日2014-01-14
公開日2015-04-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure of R468K/D560N MBD4 bound to G:T mispair DNA
To be Published
4O5C
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Structure of human DNA polymerase complexed with N7-MG as the template base in a 1-nucleotide gapped DNA
分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*(FMG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
著者Koag, M.C, Lee, S.
登録日2013-12-19
公開日2014-07-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.363 Å)
主引用文献Transition-state destabilization reveals how human DNA polymerase beta proceeds across the chemically unstable lesion N7-methylguanine.
Nucleic Acids Res., 42, 2014
4FCV
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Crystal structure of the C-terminal domain of ClpB
分子名称: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB
著者Biter, A.B, Lee, S, Sung, N, Tsai, F.T.F.
登録日2012-05-25
公開日2012-07-18
最終更新日2012-08-22
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural basis for intersubunit signaling in a protein disaggregating machine.
Proc.Natl.Acad.Sci.USA, 109, 2012
4PGQ
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Structure of human DNA polymerase beta complexed with G in the template base paired with incoming non-hydrolyzable TTP
分子名称: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
著者Koag, M.C, Lee, S.
登録日2014-05-02
公開日2014-10-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The spontaneous replication error and the mismatch discrimination mechanisms of human DNA polymerase beta.
Nucleic Acids Res., 42, 2015
4PHP
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Structure of human DNA polymerase beta complexed with T in the template base paired with incoming non-hydrolyzable GTP and MANGANESE
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*CP*GP*AP*CP*TP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ...
著者Koag, M.C, Lee, S.
登録日2014-05-06
公開日2015-05-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The spontaneous base substitution mechanisms of human DNA polymerase beta
To Be Published

221716

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