7M5X
| Human ATP13A2 in the outward-facing E2 state bound to spermine and beryllium fluoride | 分子名称: | (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, BERYLLIUM TRIFLUORIDE ION, ... | 著者 | Lee, K.P.K. | 登録日 | 2021-03-25 | 公開日 | 2022-03-30 | 最終更新日 | 2022-04-27 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structural mechanisms for gating and ion selectivity of the human polyamine transporter ATP13A2. Mol.Cell, 81, 2021
|
|
7M5Y
| human ATP13A2 in the outward-facing E2 state bound to spermine and magnesium fluoride | 分子名称: | (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | 著者 | Lee, K.P.K. | 登録日 | 2021-03-25 | 公開日 | 2022-03-30 | 最終更新日 | 2022-04-27 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural mechanisms for gating and ion selectivity of the human polyamine transporter ATP13A2. Mol.Cell, 81, 2021
|
|
7M5V
| human ATP13A2 in the AMPPNP-bound occluded state | 分子名称: | (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, 1-DODECANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Lee, K.P.K. | 登録日 | 2021-03-24 | 公開日 | 2022-03-30 | 最終更新日 | 2022-04-27 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural mechanisms for gating and ion selectivity of the human polyamine transporter ATP13A2. Mol.Cell, 81, 2021
|
|
6C3P
| Cryo-EM structure of human KATP bound to ATP and ADP in propeller form | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | 著者 | Lee, K.P.K, Chen, J, MacKinnon, R. | 登録日 | 2018-01-10 | 公開日 | 2018-01-24 | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | 主引用文献 | Molecular structure of human KATP in complex with ATP and ADP. Elife, 6, 2017
|
|
6C3O
| Cryo-EM structure of human KATP bound to ATP and ADP in quatrefoil form | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | 著者 | Lee, K.P.K, Chen, J, MacKinnon, R. | 登録日 | 2018-01-10 | 公開日 | 2018-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Molecular structure of human KATP in complex with ATP and ADP Elife, 6, 2017
|
|
3LJ1
| IRE1 complexed with Cdk1/2 Inhibitor III | 分子名称: | 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE, Serine/threonine-protein kinase/endoribonuclease IRE1 | 著者 | Lee, K.P.K, Sicheri, F. | 登録日 | 2010-01-25 | 公開日 | 2010-05-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.33 Å) | 主引用文献 | Flavonol activation defines an unanticipated ligand-binding site in the kinase-RNase domain of IRE1. Mol.Cell, 38, 2010
|
|
3LJ2
| IRE1 complexed with JAK Inhibitor I | 分子名称: | 2-TERT-BUTYL-9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLINE-7-ONE, Serine/threonine-protein kinase/endoribonuclease IRE1 | 著者 | Lee, K.P.K, Sicheri, F. | 登録日 | 2010-01-25 | 公開日 | 2010-05-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.33 Å) | 主引用文献 | Flavonol activation defines an unanticipated ligand-binding site in the kinase-RNase domain of IRE1. Mol.Cell, 38, 2010
|
|
3LJ0
| IRE1 complexed with ADP and Quercetin | 分子名称: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Lee, K.P.K, Sicheri, F. | 登録日 | 2010-01-25 | 公開日 | 2010-05-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Flavonol activation defines an unanticipated ligand-binding site in the kinase-RNase domain of IRE1. Mol.Cell, 38, 2010
|
|