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PDB: 784 件

7C4X
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Crystal structure of germination protease from the spore-forming bacterium Paenisporosarcina sp. TG-20 in its inactive form
分子名称: germination protease
著者Lee, J.H, Lee, C.W.
登録日2020-05-18
公開日2021-03-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural insights into the psychrophilic germinal protease PaGPR and its autoinhibitory loop.
J.Microbiol, 58, 2020
2B02
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BU of 2b02 by Molmil
Crystal Structure of ARNT PAS-B Domain
分子名称: Aryl hydrocarbon receptor nuclear translocator
著者Lee, J, Botuyan, M.V, Nomine, Y, Ohh, M, Thompson, J.R, Mer, G.
登録日2005-09-12
公開日2006-10-24
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure and Binding Properties of ARNT PAS-B Heterodimerization Domain
To be Published
5AWN
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BU of 5awn by Molmil
Crystal structure of Human anti-HIV-1 broadly neutralizing antibody 3BC176 Fab
分子名称: Heavy chain of 3BC176 Fab, Light chain of 3BC176 Fab
著者Lee, J.H, Wilson, I.A, Ward, A.B.
登録日2015-07-06
公開日2015-11-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.887 Å)
主引用文献Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike.
Nat Commun, 6, 2015
2QHR
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BU of 2qhr by Molmil
Crystal structure of the 13F6-1-2 Fab fragment bound to its Ebola virus glycoprotein peptide epitope.
分子名称: 13F6-1-2 Fab fragment V lambda x light chain, 13F6-1-2 Fab fragment heavy chain, Envelope glycoprotein peptide
著者Lee, J.E, Kuehne, A, Abelson, D.M, Fusco, M.L, Hart, M.K, Saphire, E.O.
登録日2007-07-02
公開日2008-01-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Complex of a protective antibody with its Ebola virus GP peptide epitope: unusual features of a V lambda x light chain.
J.Mol.Biol., 375, 2008
2QQR
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BU of 2qqr by Molmil
JMJD2A hybrid tudor domains
分子名称: JmjC domain-containing histone demethylation protein 3A, SULFATE ION
著者Lee, J, Botuyan, M.V, Mer, G.
登録日2007-07-26
公開日2007-12-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor.
Nat.Struct.Mol.Biol., 15, 2008
5CCK
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BU of 5cck by Molmil
Crystal structure of Human anti-HIV-1 broadly neutralizing antibody 3BC315 Fab
分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Antibody 3BC315 Fab heavy chain, Antibody 3BC315 Fab light chain
著者Lee, J.H, Ward, A.B, Wilson, I.A.
登録日2015-07-02
公開日2015-10-07
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike.
Nat Commun, 6, 2015
2F2B
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BU of 2f2b by Molmil
Crystal structure of integral membrane protein Aquaporin AqpM at 1.68A resolution
分子名称: Aquaporin aqpM, GLYCEROL
著者Lee, J.K, Kozono, D, Remis, J, Kitagawa, Y, Agre, P, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP)
登録日2005-11-15
公開日2005-12-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structural basis for conductance by the archaeal aquaporin AqpM at 1.68 A.
Proc.Natl.Acad.Sci.Usa, 102, 2005
3H2V
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BU of 3h2v by Molmil
Human raver1 RRM1 domain in complex with human vinculin tail domain Vt
分子名称: Raver-1, Vinculin
著者Lee, J.H, Rangarajan, E.S, Yogesha, S.D, Izard, T.
登録日2009-04-14
公開日2009-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Raver1 interactions with vinculin and RNA suggest a feed-forward pathway in directing mRNA to focal adhesions
Structure, 17, 2009
3BAV
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BU of 3bav by Molmil
Crystal structure of L26A/D28N mutant of Human acidic fibroblast growth factor
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Lee, J, Blaber, M.
登録日2007-11-08
公開日2008-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3BB2
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Crystal structure of L26D/D28N mutant of Human acidic fibroblast growth factor
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Lee, J, Blaber, M.
登録日2007-11-09
公開日2008-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3UYV
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BU of 3uyv by Molmil
Crystal structure of a glycosylated ice-binding protein (LeIBP) from Arctic yeast
分子名称: Antifreeze protein, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Lee, J.H, Park, A.K, Do, H, Park, K.S, Moh, S.H, Chi, Y.M, Kim, H.J.
登録日2011-12-06
公開日2012-02-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Structural basis for the antifreeze activity of an ice-binding protein from an Arctic yeast.
J.Biol.Chem., 2012
3UYU
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Structural basis for the antifreeze activity of an ice-binding protein (LeIBP) from Arctic yeast
分子名称: Antifreeze protein, GLYCEROL
著者Lee, J.H, Park, A.K, Do, H, Park, K.S, Moh, S.H, Chi, Y.M, Kim, H.J.
登録日2011-12-06
公開日2012-02-15
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Structural basis for the antifreeze activity of an ice-binding protein from an Arctic yeast.
J.Biol.Chem., 2012
3VF0
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BU of 3vf0 by Molmil
Raver1 in complex with metavinculin L954 deletion mutant
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Ribonucleoprotein PTB-binding 1, ...
著者Lee, J.H, Vonrhein, C, Bricogne, G, Izard, T.
登録日2012-01-09
公開日2012-07-25
最終更新日2012-09-19
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献The Metavinculin Tail Domain Directs Constitutive Interactions with Raver1 and vinculin RNA.
J.Mol.Biol., 422, 2012
3QJN
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BU of 3qjn by Molmil
Structural flexibility of Shank PDZ domain is important for its binding to different ligands
分子名称: Beta-PIX, SH3 and multiple ankyrin repeat domains protein 1
著者Lee, J.H, Park, H, Park, S.J, Kim, H.J, Eom, S.H.
登録日2011-01-30
公開日2011-04-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献The structural flexibility of the shank1 PDZ domain is important for its binding to different ligands
Biochem.Biophys.Res.Commun., 407, 2011
7K1W
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BU of 7k1w by Molmil
PIKfyve/Fig4/Vac14 complex centered on Fig4 - map3
分子名称: Fig4 Sac homology model
著者Lees, J.A, Reinisch, K.M, Li, P.
登録日2020-09-08
公開日2020-10-21
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (5.1 Å)
主引用文献Insights into Lysosomal PI(3,5)P 2 Homeostasis from a Structural-Biochemical Analysis of the PIKfyve Lipid Kinase Complex.
Mol.Cell, 80, 2020
7K2V
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BU of 7k2v by Molmil
PIKfyve/Fig4/Vac14 complex centered on PIKfyve - map2
分子名称: 1-phosphatidylinositol 3-phosphate 5-kinase
著者Lees, J.A, Reinisch, K.M, Li, P.
登録日2020-09-09
公開日2020-10-21
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (6.6 Å)
主引用文献Insights into Lysosomal PI(3,5)P 2 Homeostasis from a Structural-Biochemical Analysis of the PIKfyve Lipid Kinase Complex.
Mol.Cell, 80, 2020
7K1Y
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BU of 7k1y by Molmil
PIKfyve/Fig4/Vac14 complex centered on Vac14 - map1
分子名称: Vac14
著者Lees, J.A, Reinisch, K.M, Li, P.
登録日2020-09-08
公開日2020-10-21
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (5.25 Å)
主引用文献Insights into Lysosomal PI(3,5)P 2 Homeostasis from a Structural-Biochemical Analysis of the PIKfyve Lipid Kinase Complex.
Mol.Cell, 80, 2020
7CM0
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BU of 7cm0 by Molmil
Crystal structure of a glutaminyl cyclase in complex with NHV-1009
分子名称: 1-(cyclopentylmethyl)-1-[3-methoxy-4-(2-morpholin-4-ylethoxy)phenyl]-3-[3-(5-methylimidazol-1-yl)propyl]urea, Glutaminyl-peptide cyclotransferase, ZINC ION
著者Lee, J.W, Song, J.Y, Jang, T.H, Ha, J.H.
登録日2020-07-23
公開日2021-12-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of highly potent human glutaminyl cyclase (QC) inhibitors as anti-Alzheimer's agents by the combination of pharmacophore-based and structure-based design.
Eur.J.Med.Chem., 226, 2021
5ACO
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BU of 5aco by Molmil
Cryo-EM structure of PGT128 Fab in complex with BG505 SOSIP.664 Env trimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 ENVELOPE GLYCOPROTEIN, ...
著者Lee, J.H, Ward, A.B.
登録日2015-08-17
公開日2015-09-30
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.36 Å)
主引用文献Model Building and Refinement of a Natively Glycosylated HIV-1 Env Protein by High-Resolution Cryoelectron Microscopy.
Structure, 23, 2015
3QJM
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BU of 3qjm by Molmil
Structural flexibility of Shank PDZ domain is important for its binding to different ligands
分子名称: Beta-PIX, SH3 and multiple ankyrin repeat domains protein 1
著者Lee, J.H, Park, H, Park, S.J, Kim, H.J, Eom, S.H.
登録日2011-01-30
公開日2011-04-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.311 Å)
主引用文献The structural flexibility of the shank1 PDZ domain is important for its binding to different ligands
Biochem.Biophys.Res.Commun., 407, 2011
2QQS
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BU of 2qqs by Molmil
JMJD2A tandem tudor domains in complex with a trimethylated histone H4-K20 peptide
分子名称: JmjC domain-containing histone demethylation protein 3A, METHYLATED HISTONE H4 PEPTIDE
著者Lee, J, Botuyan, M.V, Mer, G.
登録日2007-07-26
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor.
Nat.Struct.Mol.Biol., 15, 2008
1YTO
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BU of 1yto by Molmil
Crystal Structure of Gly19 deletion Mutant of Human Acidic Fibroblast Growth Factor
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Lee, J, Blaber, M.
登録日2005-02-10
公開日2006-01-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Conversion of type I 4:6 to 3:5 beta-turn types in human acidic fibroblast growth factor: Effects upon structure, stability, folding, and mitogenic function.
Proteins, 62, 2006
1Z4S
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BU of 1z4s by Molmil
Crystal Structure of Gly19 and Glu60 deletion mutant of Human Acidic Fibroblast Growth Factor
分子名称: Heparin-binding growth factor 1, SULFATE ION
著者Lee, J, Blaber, M.
登録日2005-03-16
公開日2006-02-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Conversion of type I 4:6 to 3:5 beta-turn types in human acidic fibroblast growth factor: Effects upon structure, stability, folding, and mitogenic function.
Proteins, 62, 2005
4MRN
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BU of 4mrn by Molmil
Structure of a bacterial Atm1-family ABC transporter
分子名称: ABC transporter related protein, LAURYL DIMETHYLAMINE-N-OXIDE, PHOSPHATE ION
著者Lee, J.Y, Yang, J.G, Zhitnitsky, D, Lewinson, O, Rees, D.C.
登録日2013-09-17
公開日2014-03-19
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for heavy metal detoxification by an Atm1-type ABC exporter.
Science, 343, 2014
4MRS
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BU of 4mrs by Molmil
Structure of a bacterial Atm1-family ABC transporter
分子名称: ABC transporter related protein, LAURYL DIMETHYLAMINE-N-OXIDE, OXIDIZED GLUTATHIONE DISULFIDE, ...
著者Lee, J.Y, Yang, J.G, Zhitnitsky, D, Lewinson, O, Rees, D.C.
登録日2013-09-17
公開日2014-03-19
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural basis for heavy metal detoxification by an Atm1-type ABC exporter.
Science, 343, 2014

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