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PDB: 98 件

4Z1H
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Crystal structure of human Trap1 with SMTIN-P01
分子名称: 8-[(6-iodo-1,3-benzodioxol-5-yl)sulfanyl]-9-[6-(triphenyl-lambda~5~-phosphanyl)hexyl]-9H-purin-6-amine, Heat shock protein 75 kDa, mitochondrial
著者Lee, C, Park, H.K, Ryu, J.H, Kang, B.H.
登録日2015-03-27
公開日2015-04-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1
J.Am.Chem.Soc., 137, 2015
4Z1I
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Crystal structure of human Trap1 with AMPPNP
分子名称: Heat shock protein 75 kDa, mitochondrial, MAGNESIUM ION, ...
著者Lee, C, Park, H.K, Ryu, J.H, Kang, B.H.
登録日2015-03-27
公開日2015-04-29
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1
J.Am.Chem.Soc., 137, 2015
1IZ3
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Dimeric structure of FIH (Factor inhibiting HIF)
分子名称: FIH, SULFATE ION
著者Lee, C, Kim, S.-J, Jeong, D.-G, Lee, S.M, Ryu, S.-E.
登録日2002-09-19
公開日2003-06-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and von Hippel-Lindau.
J.Biol.Chem., 278, 2003
1N4M
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Structure of Rb tumor suppressor bound to the transactivation domain of E2F-2
分子名称: Retinoblastoma Pocket, Transcription factor E2F2
著者Lee, C, Chang, J.H, Lee, H.S, Cho, Y.
登録日2002-10-31
公開日2003-01-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor
GENES DEV., 16, 2002
2KCC
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Solution Structure of biotinoyl domain from human acetyl-CoA carboxylase 2
分子名称: Acetyl-CoA carboxylase 2
著者Lee, C, Cheong, H, Ryu, K, Lee, J, Lee, W, Jeon, Y, Cheong, C.
登録日2008-12-19
公開日2009-02-17
最終更新日2023-09-27
実験手法SOLUTION NMR
主引用文献Biotinoyl domain of human acetyl-CoA carboxylase: Structural insights into the carboxyl transfer mechanism.
Proteins, 72, 2008
4Z1F
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Crystal structure of human Trap1 with PU-H71
分子名称: 8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE, Heat shock protein 75 kDa, mitochondrial
著者Lee, C, Park, H.K, Ryu, J.H, Kang, B.H.
登録日2015-03-27
公開日2015-04-22
実験手法X-RAY DIFFRACTION (2.703 Å)
主引用文献Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1
J.Am.Chem.Soc., 137, 2015
4Z1G
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Crystal structure of human Trap1 with BIIB-021
分子名称: 6-chloro-9-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-9H-purin-2-amine, Heat shock protein 75 kDa, mitochondrial
著者Lee, C, Park, H.K, Ryu, J.H, Kang, B.H.
登録日2015-03-27
公開日2015-04-22
最終更新日2022-10-05
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1
J.Am.Chem.Soc., 137, 2015
1QH2
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CHYMOTRYPSIN INHIBITOR (C2) FROM NICOTIANA ALATA
分子名称: PROTEIN (TRYPSIN INHIBITOR C2)
著者Lee, M.C.S, Scanlon, M.J, Anderson, M.A, Craik, D.J.
登録日1999-05-11
公開日1999-05-24
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献A novel two-chain proteinase inhibitor generated by circularization of a multidomain precursor protein.
Nat.Struct.Biol., 6, 1999
4BWZ
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Crystal structure of the sodium proton antiporter, NapA
分子名称: NA(+)/H(+) ANTIPORTER, ZINC ION
著者Lee, C, Drew, D, Cameron, A.D.
登録日2013-07-05
公開日2013-08-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.984 Å)
主引用文献A two-domain elevator mechanism for sodium/proton antiport.
Nature, 501, 2013
3L9P
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Crystal Structure of the Anaplastic Lymphoma Kinase Catalytic Domain
分子名称: Anaplastic lymphoma kinase, GLYCEROL
著者Lee, C.
登録日2010-01-05
公開日2010-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain.
Biochem.J., 430, 2010
5VRE
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Crystal structure of a lysosomal potassium-selective channel TMEM175 homolog from Chamaesiphon Minutus
分子名称: Putative integral membrane protein
著者Lee, C, Guo, J, Jiang, Y.
登録日2017-05-10
公開日2017-07-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.299 Å)
主引用文献The lysosomal potassium channel TMEM175 adopts a novel tetrameric architecture.
Nature, 547, 2017
2JTN
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NMR Solution Structure of a ldb1-LID:Lhx3-LIM complex
分子名称: LIM domain-binding protein 1, LIM/homeobox protein Lhx3, ZINC ION
著者Lee, C, Nancarrow, A.L, Mackay, J.P, Matthews, J.M.
登録日2007-08-03
公開日2008-06-17
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes
Embo J., 27, 2008
6ABQ
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Crystal structure of transcription factor from Listeria monocytogenes
分子名称: CHLORIDE ION, PadR family transcriptional regulator
著者Lee, C, Hong, M.
登録日2018-07-23
公開日2019-06-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-based molecular characterization and regulatory mechanism of the LftR transcription factor from Listeria monocytogenes: Conformational flexibilities and a ligand-induced regulatory mechanism.
Plos One, 14, 2019
3MKQ
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Crystal structure of yeast alpha/betaprime-COP subcomplex of the COPI vesicular coat
分子名称: Coatomer beta'-subunit, Coatomer subunit alpha
著者Lee, C, Goldberg, J.
登録日2010-04-15
公開日2010-07-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of coatomer cage proteins and the relationship among COPI, COPII, and clathrin vesicle coats.
Cell(Cambridge,Mass.), 142, 2010
3MKR
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Crystal structure of yeast alpha/epsilon-COP subcomplex of the COPI vesicular coat
分子名称: Coatomer subunit alpha, Coatomer subunit epsilon
著者Lee, C, Goldberg, J.
登録日2010-04-15
公開日2010-07-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of coatomer cage proteins and the relationship among COPI, COPII, and clathrin vesicle coats.
Cell(Cambridge,Mass.), 142, 2010
5H20
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X-ray structure of PadR-like Transcription factor from bacteroid fragilis
分子名称: ISOPROPYL ALCOHOL, PHOSPHATE ION, Putative PadR-family transcriptional regulatory protein, ...
著者Lee, C, Hong, M.
登録日2016-10-13
公開日2017-03-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and functional analysis of BF2549, a PadR-like transcription factor from Bacteroides fragilis.
Biochem. Biophys. Res. Commun., 483, 2017
5XEF
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BU of 5xef by Molmil
Crystal structure of flagellar chaperone from bacteria
分子名称: Flagellar protein fliS
著者Lee, C, Hong, M.
登録日2017-04-05
公開日2018-06-27
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the flagellar chaperone FliS from Bacillus cereus and an invariant proline critical for FliS dimerization and flagellin recognition
Biochem. Biophys. Res. Commun., 487, 2017
6ABT
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Crystal structure of transcription factor from Listeria monocytogenes
分子名称: PadR family transcriptional regulator
著者Lee, C, Hong, M.
登録日2018-07-23
公開日2019-06-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-based molecular characterization and regulatory mechanism of the LftR transcription factor from Listeria monocytogenes: Conformational flexibilities and a ligand-induced regulatory mechanism.
Plos One, 14, 2019
2JRL
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BU of 2jrl by Molmil
Solution structure of the beryllofluoride-activated NtrC4 receiver domain dimer
分子名称: Transcriptional regulator (NtrC family)
著者Lee, C, Hong, E, Doucleff, M, Pelton, J.G, Wemmer, D.E, Berkeley Structural Genomics Center (BSGC)
登録日2007-06-27
公開日2008-07-01
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution Structure of the Beryllofluoride-Activated NtrC4 Receiver Domain Dimer.
To be Published
2HIW
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Crystal Structure of Inactive Conformation Abl Kinase Catalytic Domain Complexed with Type II Inhibitor
分子名称: 7-AMINO-1-METHYL-3-(2-METHYL-5-{[3-(TRIFLUOROMETHYL)BENZOYL]AMINO}PHENYL)-2-OXO-2,3-DIHYDROPYRIMIDO[4,5-D]PYRIMIDIN-1-IUM, Proto-oncogene tyrosine-protein kinase ABL1
著者Lee, C.
登録日2006-06-29
公開日2006-08-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A general strategy for creating
Chem.Biol., 13, 2006
2L14
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Structure of CBP nuclear coactivator binding domain in complex with p53 TAD
分子名称: CREB-binding protein, Cellular tumor antigen p53
著者Lee, C, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
登録日2010-07-22
公開日2010-11-03
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the p53 transactivation domain in complex with the nuclear receptor coactivator binding domain of CREB binding protein.
Biochemistry, 49, 2010
2LKP
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solution structure of apo-NmtR
分子名称: HTH-type transcriptional regulator NmtR
著者Lee, C, Giedroc, D.
登録日2011-10-18
公開日2012-04-18
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structure of Mycobacterium tuberculosis NmtR in the Apo State: Insights into Ni(II)-Mediated Allostery.
Biochemistry, 51, 2012
2L6I
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Solution structure of coronaviral stem-loop 2 (SL2)
分子名称: RNA (5'-R(*GP*AP*UP*CP*UP*CP*UP*UP*GP*UP*AP*GP*AP*UP*CP*A)-3')
著者Lee, C, Li, L, Giedroc, D.P.
登録日2010-11-21
公開日2011-03-23
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The solution structure of coronaviral stem-loop 2 (SL2) reveals a canonical CUYG tetraloop fold.
Febs Lett., 585, 2011
7MCI
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MoFe protein from Azotobacter vinelandii with a sulfur-replenished cofactor
分子名称: 3-HYDROXY-3-CARBOXY-ADIPIC ACID, CALCIUM ION, FE(8)-S(7) CLUSTER, ...
著者Kang, W, Lee, C, Hu, Y, Ribbe, M.W.
登録日2021-04-02
公開日2022-05-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Evidence of substrate binding and product release via belt-sulfur mobilization of the nitrogenase cofactor
Nat Catal, 5, 2022
2FS4
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Ketopiperazine-Based Renin Inhibitors: Optimization of the C ring
分子名称: (6R)-6-({[1-(3-HYDROXYPROPYL)-1,7-DIHYDROQUINOLIN-7-YL]OXY}METHYL)-1-(4-{3-[(2-METHOXYBENZYL)OXY]PROPOXY}PHENYL)PIPERAZIN-2-ONE, Renin
著者Holsworth, D.D, Cai, C, Cheng, X.-M, Cody, W.L, Downing, D.M, Erasga, N, Lee, C, Powell, N.A, Edmunds, J.J, Stier, M, Jalaie, M, Zhang, E, McConnell, P, Ryan, M.J, Bryant, J, Li, T, Kasani, A, Hall, E, Subedi, R, Rahim, M, Maiti, S.
登録日2006-01-20
公開日2006-06-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Ketopiperazine-Based Renin Inhibitors: Optimization of the "C" Ring
BIOORG.MED.CHEM.LETT., 16, 2006

 

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