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PDB: 229 件

1QQP
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FOOT-AND-MOUTH DISEASE VIRUS/ OLIGOSACCHARIDE RECEPTOR COMPLEX.
分子名称: 2-O-sulfo-alpha-L-gulopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-gulopyranuronic acid, PROTEIN (GENOME POLYPROTEIN)
著者Fry, E.E, Lea, S.M, Jackson, T, Newman, J.W.I, Ellard, F.M, Blakemore, W.E, Abu-Ghazaleh, R, Samuel, A, King, A.M.Q, Stuart, D.I.
登録日1999-05-20
公開日1999-06-18
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structure and function of a foot-and-mouth disease virus-oligosaccharide receptor complex.
EMBO J., 18, 1999
2BOU
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EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with barium.
分子名称: BARIUM ION, CACODYLATE ION, CALCIUM ION, ...
著者Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M.
登録日2005-04-14
公開日2006-10-18
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
2BOX
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EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with strontium.
分子名称: CACODYLATE ION, CHLORIDE ION, EGF-LIKE MODULE CONTAINING MUCIN-LIKE HORMONE RECEPTOR-LIKE 2 PRECURSOR, ...
著者Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M.
登録日2005-04-14
公開日2006-10-18
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
2BO2
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EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with calcium.
分子名称: CACODYLATE ION, CALCIUM ION, EGF-LIKE MODULE CONTAINING MUCIN-LIKE HORMONE RECEPTOR-LIKE 2 PRECURSOR
著者Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M.
登録日2005-04-07
公開日2006-08-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
1OJY
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Decay accelerating factor (cd55): the structure of an intact human complement regulator.
分子名称: ACETATE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, ...
著者Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, R.A, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
登録日2003-07-16
公開日2004-01-07
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
1OK2
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Decay accelerating factor (CD55): the structure of an intact human complement regulator.
分子名称: ACETATE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, ...
著者Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, R.A, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
登録日2003-07-16
公開日2004-01-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
1OJV
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Decay accelerating factor (CD55): the structure of an intact human complement regulator.
分子名称: ACETATE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, ...
著者Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, C.M, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
登録日2003-07-16
公開日2004-01-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
1OK1
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Decay accelerating factor (cd55) : the structure of an intact human complement regulator.
分子名称: ACETATE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, ...
著者Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, R.A, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
登録日2003-07-16
公開日2004-01-07
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
1OK3
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Decay accelerating factor (cd55): the structure of an intact human complement regulator.
分子名称: ACETATE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, ...
著者Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, R.A, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
登録日2003-07-16
公開日2004-01-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
2CA5
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MxiH needle protein of Shigella Flexneri (monomeric form, residues 1- 78)
分子名称: GLYCEROL, ISOPROPYL ALCOHOL, MXIH, ...
著者Deane, J.E, Roversi, P, Cordes, F.S, Johnson, S, Kenjale, R, Picking, W.L, Picking, W.D, Blocker, A.J, Lea, S.M.
登録日2005-12-16
公開日2006-08-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular Model of a Type III Secretion System Needle: Implications for Host-Cell Sensing
Proc.Natl.Acad.Sci.USA, 103, 2006
1OJW
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Decay accelerating factor (CD55): the structure of an intact human complement regulator.
分子名称: COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, SULFATE ION
著者Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, C.M, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
登録日2003-07-16
公開日2004-01-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
1OK9
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Decay accelerating factor (CD55): The structure of an intact human complement regulator.
分子名称: ACETATE ION, CHLORIDE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, ...
著者Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, R.A, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
登録日2003-07-21
公開日2004-01-07
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
3ZD1
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BU of 3zd1 by Molmil
STRUCTURE OF THE TWO C-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 2
分子名称: 1,2-ETHANEDIOL, COMPLEMENT FACTOR H-RELATED PROTEIN 2
著者Caesar, J.J.E, Goicoechea de Jorge, E, Pickering, M.C, Lea, S.M.
登録日2012-11-23
公開日2013-03-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Dimerization of Complement Factor H-Related Proteins Modulates Complement Activation in Vivo.
Proc.Natl.Acad.Sci.USA, 110, 2013
2YF2
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Crystal structure of the oligomerisation domain of C4b-binding protein from Gallus gallus
分子名称: 1,2-ETHANEDIOL, ACETATE ION, C4B BINDING PROTEIN
著者Caesar, J.J.E, Hill, F, Lea, S.M.
登録日2011-04-01
公開日2012-04-18
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Crystal Structure of the Oligomerisation Domain of C4B-Binding Protein from Gallus Gallus
To be Published
2XRC
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Human complement factor I
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, HUMAN COMPLEMENT FACTOR I
著者Roversi, P, Johnson, S, Lea, S.M.
登録日2010-09-13
公開日2011-07-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Structural Basis for Complement Factor I Control and its Disease-Associated Sequence Polymorphisms.
Proc.Natl.Acad.Sci.USA, 108, 2011
2XXS
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Solution structure of the N-terminal domain of the Shigella type III secretion protein MxiG
分子名称: PROTEIN MXIG
著者McDowell, M.A, Johnson, S, Deane, J.E, McDonnell, J.M, Lea, S.M.
登録日2010-11-11
公開日2011-07-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural and Functional Studies on the N-Terminal Domain of the Shigella Type III Secretion Protein Mxig.
J.Biol.Chem., 286, 2011
2XGA
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MTSL spin-labelled Shigella Flexneri Spa15
分子名称: S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, SURFACE PRESENTATION OF ANTIGENS PROTEIN SPAK
著者Lillington, J.E.D, Johnson, S, Lea, S.M.
登録日2010-06-02
公開日2010-12-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Shigella Flexneri Spa15 Crystal Structure Verified in Solution by Double Electron Electron Resonance.
J.Mol.Biol., 405, 2011
2YEZ
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COMPLEX OF A B21 CHICKEN MHC CLASS I MOLECULE AND A 10MER CHICKEN PEPTIDE
分子名称: 14-3-3 PROTEIN THETA, BETA-2-MICROGLOBULIN, MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I GLYCOPROTEIN HAPLOTYPE B21
著者Chappell, P, Roversi, P, Harrison, M.C, Mears, L.E, Kaufman, J.F, Lea, S.M.
登録日2011-03-31
公開日2012-04-11
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding.
Elife, 4, 2015
2YBY
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Structure of domains 6 and 7 of the mouse complement regulator Factor H
分子名称: 1,2-ETHANEDIOL, COMPLEMENT FACTOR H
著者Everett, R.J, Caesar, J.J.E, Johnson, S.J, Tang, C.M, Lea, S.M.
登録日2011-03-30
公開日2012-04-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Design and Evaluation of Meningococcal Vaccines Through Structure-Based Modification of Host and Pathogen Molecules.
Plos Pathog., 8, 2012
2CM4
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The complement inhibitor OmCI in complex with ricinoleic acid
分子名称: ACETATE ION, COMPLEMENT INHIBITOR, RICINOLEIC ACID
著者Roversi, P, Johnson, S, Lissina, O, Paesen, G.C, Boland, W, Nunn, M.A, Lea, S.M.
登録日2006-05-04
公開日2007-05-01
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Structure of Omci, a Novel Lipocalin Inhibitor of the Complement System.
J.Mol.Biol., 369, 2007
2YEQ
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Structure of PhoD
分子名称: 1,2-ETHANEDIOL, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ALKALINE PHOSPHATASE D, ...
著者Lillington, J.E.D, Rodriguez, F, Roversi, P, Johnson, S.J, Berks, B, Lea, S.M.
登録日2011-03-30
公開日2012-04-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal Structure of the Bacillus Subtilis Phosphodiesterase Phod Reveals an Iron and Calcium-Containing Active Site.
J.Biol.Chem., 289, 2014
2CM9
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The complement inhibitor OmCI in complex with ricinoleic acid
分子名称: ACETATE ION, COMPLEMENT INHIBITOR, RICINOLEIC ACID
著者Roversi, P, Johnson, S, Lissina, O, Paesen, G.C, Boland, W, Nunn, M.A, Lea, S.M.
登録日2006-05-04
公開日2007-05-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Structure of Omci, a Novel Lipocalin Inhibitor of the Complement System.
J.Mol.Biol., 369, 2007
2J8B
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High resolution structure of human CD59
分子名称: CD59 GLYCOPROTEIN
著者Leath, K.J, Johnson, S, Roversi, P, Morgan, B.P, Smith, R.A.G, Lea, S.M.
登録日2006-10-24
公開日2007-08-07
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献High-Resolution Structures of Bacterially Expressed Soluble Human Cd59.
Acta Crystallogr.,Sect.F, 63, 2007
1UOT
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HUMAN CD55 DOMAINS 3 & 4
分子名称: COMPLEMENT DECAY-ACCELERATING FACTOR
著者Williams, P, Chaudhry, Y, Goodfellow, I.G, Billington, J, Spiller, B, Evans, D.J, Lea, S.M.
登録日2003-09-23
公開日2003-09-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Mapping Cd55 Function. The Structure of Two Pathogen-Binding Domains at 1.7 A
J.Biol.Chem., 278, 2003
1W3Z
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SeMet derivative of BbCRASP-1 from Borrelia Burgdorferi
分子名称: BBCRASP-1
著者Cordes, F.S, Roversi, P, Goodstadt, L, Ponting, C, Kraiczy, P, Skerka, C, Kirschfink, M, Simon, M.M, Brade, V, Zipfel, P, Wallich, R, Lea, S.M.
登録日2004-07-21
公開日2005-02-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献A Novel Fold for the Factor H-Binding Protein Bbcrasp-1 of Borrelia Burgdorferi
Nat.Struct.Mol.Biol., 12, 2005

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