6XNG
| MHC-like protein complex structure | 分子名称: | (3R)-N-[(2S,3R)-1-(alpha-D-galactopyranosyloxy)-3-hydroxyheptadecan-2-yl]-3-hydroxyheptadecanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | 著者 | Thirunavukkarasu, P, Le Nours, J, Rossjohn, J. | 登録日 | 2020-07-02 | 公開日 | 2021-11-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Host immunomodulatory lipids created by symbionts from dietary amino acids. Nature, 600, 2021
|
|
8SGM
| |
8SGB
| |
5L2J
| Crystal Structure of human CD1b in complex with C36-GMM | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-O-[(2R,3R)-3-hydroxy-2-tetradecyldocosanoyl]-alpha-L-idopyranose, ACETATE ION, ... | 著者 | Gras, S, Shahine, A, Le Nours, J, Rossjohn, J. | 登録日 | 2016-08-02 | 公開日 | 2016-11-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | T cell receptor recognition of CD1b presenting a mycobacterial glycolipid. Nat Commun, 7, 2016
|
|
5L2K
| Crystal structure of GEM42 TCR-CD1b-GMM complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-O-[(2R,3R)-3-hydroxy-2-tetradecyldocosanoyl]-alpha-L-idopyranose, Beta-2-microglobulin, ... | 著者 | Gras, S, Shahine, A, Le Nours, J, Rossjohn, J. | 登録日 | 2016-08-02 | 公開日 | 2016-11-16 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | T cell receptor recognition of CD1b presenting a mycobacterial glycolipid. Nat Commun, 7, 2016
|
|
7RYN
| CD1a-sulfatide-gdTCR complex | 分子名称: | (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wegrecki, M, Le Nours, J, Rossjohn, J. | 登録日 | 2021-08-25 | 公開日 | 2022-05-18 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Atypical sideways recognition of CD1a by autoreactive gamma delta T cell receptors. Nat Commun, 13, 2022
|
|
7RYO
| CD1a-dideoxymycobactin-gdTCR complex | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, SULFATE ION, ... | 著者 | Wegrecki, M, Le Nours, J, Rossjohn, J. | 登録日 | 2021-08-25 | 公開日 | 2022-05-18 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Atypical sideways recognition of CD1a by autoreactive gamma delta T cell receptors. Nat Commun, 13, 2022
|
|
7RYM
| CD1a-endo-gdTCR complex | 分子名称: | Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... | 著者 | Wegrecki, M, Le Nours, J, Rossjohn, J. | 登録日 | 2021-08-25 | 公開日 | 2022-05-18 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Atypical sideways recognition of CD1a by autoreactive gamma delta T cell receptors. Nat Commun, 13, 2022
|
|
7RYL
| T cell receptor CO3 | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, T cell receptor delta variable 1,T cell receptor alpha chain constant, ... | 著者 | Wegrecki, M, Le Nours, J, Rossjohn, J. | 登録日 | 2021-08-25 | 公開日 | 2022-05-18 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Atypical sideways recognition of CD1a by autoreactive gamma delta T cell receptors. Nat Commun, 13, 2022
|
|
6MRA
| Diversity in the type II Natural Killer T cell receptor repertoire and antigen specificity leads to differing CD1d docking strategies | 分子名称: | TCR alpha chain, TCR beta-chain | 著者 | Sundararaj, S, Le Nours, J, Praveena, T, Rossjohn, J. | 登録日 | 2018-10-12 | 公開日 | 2019-09-18 | 最終更新日 | 2020-01-22 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Distinct CD1d docking strategies exhibited by diverse Type II NKT cell receptors. Nat Commun, 10, 2019
|
|
6NUX
| CD1a-lipid binary complex | 分子名称: | (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol, 1,2-ETHANEDIOL, Beta-2-microglobulin, ... | 著者 | Wegrecki, M, Le Nours, J, Rossjohn, J. | 登録日 | 2019-02-03 | 公開日 | 2020-01-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Human T cell response to CD1a and contact dermatitis allergens in botanical extracts and commercial skin care products. Sci Immunol, 5, 2020
|
|
6MSS
| Diversity in the type II Natural Killer T cell receptor repertoire and antigen specificity leads to differing CD1d docking strategies | 分子名称: | (2S)-2-(heptadecanoyloxy)-3-{[(10S)-10-methyloctadecanoyl]oxy}propyl alpha-D-glucopyranosiduronic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Sundararaj, S, Le Nours, J, Praveena, T, Rossjohn, J. | 登録日 | 2018-10-18 | 公開日 | 2019-10-02 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Distinct CD1d docking strategies exhibited by diverse Type II NKT cell receptors. Nat Commun, 10, 2019
|
|
6BMK
| Crystal structure of MHC-I like protein | 分子名称: | (2R)-1-(decanoyloxy)-3-(phosphonooxy)propan-2-yl octadecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Khandokar, Y.B, Le Nours, J, Rossjohn, J. | 登録日 | 2017-11-15 | 公開日 | 2018-01-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Differing roles of CD1d2 and CD1d1 proteins in type I natural killer T cell development and function. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6BMH
| Crystal structure of MHC-I like protein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d2, ... | 著者 | Khandokar, Y.B, Le Nours, J, Rossjohn, J. | 登録日 | 2017-11-14 | 公開日 | 2018-01-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.298 Å) | 主引用文献 | Differing roles of CD1d2 and CD1d1 proteins in type I natural killer T cell development and function. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
7K0Z
| Marsupial T cell receptor Spl_157 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, T cell receptor gamma chain, T cell receptor mu chain | 著者 | Wegrecki, M, Kannan Sivaraman, K, Le Nours, J, Rossjohn, J. | 登録日 | 2020-09-06 | 公開日 | 2021-03-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | The molecular assembly of the marsupial gamma mu T cell receptor defines a third T cell lineage. Science, 371, 2021
|
|
7K0X
| Marsupial T cell receptor Spl_145 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, T cell receptor gamma chain, T cell receptor mu chain, ... | 著者 | Wegrecki, M, Kannan Sivaraman, K, Le Nours, J, Rossjohn, J. | 登録日 | 2020-09-06 | 公開日 | 2021-03-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | The molecular assembly of the marsupial gamma mu T cell receptor defines a third T cell lineage. Science, 371, 2021
|
|
7L15
| Marsupial T cell receptor Spl_118 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, T cell receptor gamma chain, ... | 著者 | Wegrecki, M, Kannan Sivaraman, K, Praveena, T, Le Nours, J, Rossjohn, J. | 登録日 | 2020-12-14 | 公開日 | 2021-03-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | The molecular assembly of the marsupial gamma mu T cell receptor defines a third T cell lineage. Science, 371, 2021
|
|
4APQ
| Crystal structure of autoreactive-Valpha14-Vbeta6 NKT TCR in complex with CD1d-sulfatide | 分子名称: | (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIGEN-PRESENTING GLYCOPROTEIN CD1D1, ... | 著者 | Clarke, A.J, Le Nours, J, Rossjohn, J. | 登録日 | 2012-04-05 | 公開日 | 2013-04-24 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Type-II Natural Killer T Cell Antigen Receptor Mediated Recognition of Cd1D-Sulfatide To be Published
|
|
7KP1
| CD1a-42:2 SM binary complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-2-microglobulin, T-cell surface glycoprotein CD1a, ... | 著者 | Wegrecki, M, Le Nours, J, Rossjohn, J. | 登録日 | 2020-11-10 | 公開日 | 2021-05-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | CD1a selectively captures endogenous cellular lipids that broadly block T cell response. J.Exp.Med., 218, 2021
|
|
7KP0
| CD1a-42:1 SM binary complex | 分子名称: | (4R,7S)-4-hydroxy-7-[(1S,2E)-1-hydroxyhexadec-2-en-1-yl]-N,N,N-trimethyl-4,9-dioxo-3,5-dioxa-8-aza-4lambda~5~-phosphadotriacontan-1-aminium, 1,2-ETHANEDIOL, Beta-2-microglobulin, ... | 著者 | Wegrecki, M, Le Nours, J, Rossjohn, J. | 登録日 | 2020-11-10 | 公開日 | 2021-05-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | CD1a selectively captures endogenous cellular lipids that broadly block T cell response. J.Exp.Med., 218, 2021
|
|
7KOZ
| CD1a-36:2 SM binary complex | 分子名称: | (4S,7S,17Z)-4-hydroxy-7-[(1S,2E)-1-hydroxyhexadec-2-en-1-yl]-N,N,N-trimethyl-4,9-dioxo-3,5-dioxa-8-aza-4lambda~5~-phosphahexacos-17-en-1-aminium, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wegrecki, M, Le Nours, J, Rossjohn, J. | 登録日 | 2020-11-10 | 公開日 | 2021-05-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | CD1a selectively captures endogenous cellular lipids that broadly block T cell response. J.Exp.Med., 218, 2021
|
|
4L4T
| Structure of human MAIT TCR in complex with human MR1-6-FP | 分子名称: | 2-amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde, Beta-2-microglobulin, MAIT T-cell receptor alpha chain, ... | 著者 | Patel, O, Kjer-Nielsen, L, Le Nours, J, Eckle, S.B.G, Birkinshaw, R.W, Beddoe, T, Corbett, A.J, Liu, L, Miles, J.J, Meehan, B, Reantragoon, R, Sandoval-Romero, M.L, Sullivan, L.C, Brooks, A.G, Chen, Z, Fairlie, D.P, McCluskey, J, Rossjohn, J. | 登録日 | 2013-06-09 | 公開日 | 2013-07-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Recognition of vitamin B metabolites by mucosal-associated invariant T cells. Nat Commun, 4, 2013
|
|
4L4V
| Structure of human MAIT TCR in complex with human MR1-RL-6-Me-7-OH | 分子名称: | 1-deoxy-1-(7-hydroxy-6-methyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Patel, O, Kjer-Nielsen, L, Le Nours, J, Eckle, S.B.G, Birkinshaw, R.W, Beddoe, T, Corbett, A.J, Liu, L, Miles, J.J, Meehan, B, Reantragoon, R, Sandoval-Romero, M.L, Sullivan, L.C, Brooks, A.G, Chen, Z, Fairlie, D.P, McCluskey, J, Rossjohn, J. | 登録日 | 2013-06-09 | 公開日 | 2013-07-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Recognition of vitamin B metabolites by mucosal-associated invariant T cells. Nat Commun, 4, 2013
|
|
4LFH
| Crystal Structure of 9C2 TCR | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 9C2 TCR delta chain, 9C2 TCR gamma chain, ... | 著者 | Uldrich, A.P, Le Nours, J, Pellicci, D.G, Gras, S, Rossjohn, J, Godfrey, D.I. | 登録日 | 2013-06-26 | 公開日 | 2013-10-02 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | CD1d-lipid antigen recognition by the gamma delta TCR. Nat.Immunol., 14, 2013
|
|
4LHU
| Crystal Structure of 9C2 TCR bound to CD1d | 分子名称: | (15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]tetracos-15-enamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Uldrich, A.P, Le Nours, J, Pellicci, D.G, Gras, S, Rossjohn, J, Godfrey, D.I. | 登録日 | 2013-07-01 | 公開日 | 2013-10-02 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | 主引用文献 | CD1d-lipid antigen recognition by the gamma delta TCR. Nat.Immunol., 14, 2013
|
|