6OTT
 
 | | Structure of PurF in complex with ppApp | | Descriptor: | Amidophosphoribosyltransferase, PurF, MAGNESIUM ION, ... | | Authors: | Grant, R.A, Wang, B, Laub, M.T. | | Deposit date: | 2019-05-03 | | Release date: | 2019-11-06 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | An interbacterial toxin inhibits target cell growth by synthesizing (p)ppApp.
Nature, 575, 2019
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6X0A
 | | X-ray structure of a chimeric ParDE toxin-antitoxin complex from Mesorhizobium opportunistum | | Descriptor: | 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Plasmid stabilization system, Putative addiction module antidote protein, ... | | Authors: | Lite, T.L, Grant, R.A, Laub, M.T. | | Deposit date: | 2020-05-15 | | Release date: | 2020-11-25 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Uncovering the basis of protein-protein interaction specificity with a combinatorially complete library.
Elife, 9, 2020
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5CEG
 | | X-ray structure of toxin/anti-toxin complex from Mesorhizobium opportunistum | | Descriptor: | Addiction module antidote protein, CopG/Arc/MetJ family, GLYCEROL, ... | | Authors: | Aakre, C.D, Herrou, J, Crosson, S, Laub, M.T. | | Deposit date: | 2015-07-06 | | Release date: | 2015-11-11 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | Evolving New Protein-Protein Interaction Specificity through Promiscuous Intermediates.
Cell, 163, 2015
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6CZF
 | | The structure of E. coli PurF in complex with ppGpp-Mg | | Descriptor: | Amidophosphoribosyltransferase, GUANOSINE-5',3'-TETRAPHOSPHATE, MAGNESIUM ION | | Authors: | Wang, B, Grant, R.A, Laub, M.T. | | Deposit date: | 2018-04-09 | | Release date: | 2018-10-10 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.949 Å) | | Cite: | Affinity-based capture and identification of protein effectors of the growth regulator ppGpp.
Nat. Chem. Biol., 15, 2019
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4JAS
 | | Structural basis of a rationally rewired protein-protein interface (HK853mutant A268V, A271G, T275M, V294T and D297E and RR468mutant V13P, L14I, I17M and N21V) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Histidine kinase, MAGNESIUM ION, ... | | Authors: | Podgornaia, A.I, Casino, P, Marina, A, Laub, M.T. | | Deposit date: | 2013-02-19 | | Release date: | 2013-09-04 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling
Structure, 21, 2013
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4JAU
 | | Structural basis of a rationally rewired protein-protein interface (HK853mutant A268V, A271G, T275M, V294T and D297E) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Histidine kinase | | Authors: | Podgornaia, A.I, Casino, P, Marina, A, Laub, M.T. | | Deposit date: | 2013-02-19 | | Release date: | 2013-09-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling
Structure, 21, 2013
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4JA2
 | | Structural basis of a rationally rewired protein-protein interface (RR468mutant V13P, L14I, I17M and N21V) | | Descriptor: | ACETATE ION, MAGNESIUM ION, Response regulator, ... | | Authors: | Podgornaia, A.I, Casino, P, Marina, A, Laub, M.T. | | Deposit date: | 2013-02-18 | | Release date: | 2013-09-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling
Structure, 21, 2013
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4JAV
 | | Structural basis of a rationally rewired protein-protein interface (HK853wt and RR468mutant V13P, L14I, I17M and N21V) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Histidine kinase, ... | | Authors: | Podgornaia, A.I, Casino, P, Marina, A, Laub, M.T. | | Deposit date: | 2013-02-19 | | Release date: | 2013-09-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling
Structure, 21, 2013
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6VWP
 | | Crystal structure of E. coli guanosine kinase in complex with ppGpp | | Descriptor: | GUANOSINE, GUANOSINE-5',3'-TETRAPHOSPHATE, Inosine-guanosine kinase, ... | | Authors: | Wang, B, Grant, R.A, Laub, M.T. | | Deposit date: | 2020-02-20 | | Release date: | 2020-10-07 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.45 Å) | | Cite: | ppGpp Coordinates Nucleotide and Amino-Acid Synthesis in E. coli During Starvation.
Mol.Cell, 80, 2020
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6VWO
 | | Crystal structure of E. coli guanosine kinase | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE, Inosine-guanosine kinase, ... | | Authors: | Wang, B, Grant, R.A, Laub, M.T. | | Deposit date: | 2020-02-20 | | Release date: | 2020-10-07 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | ppGpp Coordinates Nucleotide and Amino-Acid Synthesis in E. coli During Starvation.
Mol.Cell, 80, 2020
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