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PDB: 38 件
3JA9
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Structure of native human PCNA
分子名称: Proliferating cell nuclear antigen
著者Lau, W.C.Y, Li, Y, Zhang, Q, Huen, M.S.Y.
登録日2015-05-19
公開日2015-12-09
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (22 Å)
主引用文献Molecular architecture of the Ub-PCNA/Pol eta complex bound to DNA
Sci Rep, 5, 2015
3JAA
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HUMAN DNA POLYMERASE ETA in COMPLEX WITH NORMAL DNA AND INCO NUCLEOTIDE (NRM)
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*T*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3, DNA (5'-D(*TP*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
著者Lau, W.C.Y, Li, Y, Zhang, Q, Huen, M.S.Y.
登録日2015-05-19
公開日2015-12-23
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (22 Å)
主引用文献Molecular architecture of the Ub-PCNA/Pol eta complex bound to DNA
Sci Rep, 5, 2015
3JBZ
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Crystal structure of mTOR docked into EM map of dimeric ATM kinase
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Serine/threonine-protein kinase mTOR, ...
著者Lau, W.C.Y.
登録日2015-11-03
公開日2016-11-16
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (28 Å)
主引用文献Structure of the human dimeric ATM kinase.
Cell Cycle, 15, 2016
3J0J
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BU of 3j0j by Molmil
Fitted atomic models of Thermus thermophilus V-ATPase subunits into cryo-EM map
分子名称: ADENOSINE-5'-DIPHOSPHATE, V-type ATP synthase alpha chain, V-type ATP synthase beta chain, ...
著者Lau, W.C.Y, Rubinstein, J.L.
登録日2011-08-24
公開日2011-12-14
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (9.7 Å)
主引用文献Subnanometre-resolution structure of the intact Thermus thermophilus H+-driven ATP synthase.
Nature, 481, 2012
7BZW
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Structure of Hsp21
分子名称: Heat shock protein 21, chloroplastic
著者Lau, W.C.Y.
登録日2020-04-28
公開日2021-04-28
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural basis of substrate recognition and thermal protection by a small heat shock protein.
Nat Commun, 12, 2021
7BZY
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Hsp21-DXPS
分子名称: 1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic, Heat shock protein 21
著者Lau, W.C.Y.
登録日2020-04-29
公開日2021-07-28
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis of substrate recognition and thermal protection by a small heat shock protein.
Nat Commun, 12, 2021
7BZX
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DXPS
分子名称: 1-deoxy-D-xylulose-5-phosphate synthase, chloroplastic
著者Lau, W.C.Y.
登録日2020-04-28
公開日2021-11-17
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis of substrate recognition and thermal protection by a small heat shock protein.
Nat Commun, 12, 2021
1ITF
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BU of 1itf by Molmil
INTERFERON ALPHA-2A, NMR, 24 STRUCTURES
分子名称: INTERFERON ALPHA-2A
著者Klaus, W, Gsell, B, Labhardt, A.M, Wipf, B, Senn, H.
登録日1997-08-22
公開日1997-12-03
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献The three-dimensional high resolution structure of human interferon alpha-2a determined by heteronuclear NMR spectroscopy in solution.
J.Mol.Biol., 274, 1997
2Q8Z
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BU of 2q8z by Molmil
Crystal structure of Plasmodium falciparum orotidine 5'-phosphate decarboxylase complexed with 6-amino-UMP
分子名称: 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 6-AMINOURIDINE 5'-MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
著者Liu, Y, Lau, W, Bello, A.M, Kotra, L.P, Hui, R, Pai, E.F.
登録日2007-06-12
公開日2008-01-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure-Activity Relationships of C6-Uridine Derivatives Targeting Plasmodia Orotidine Monophosphate Decarboxylase.
J.Med.Chem., 51, 2008
2Q8L
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Crystal structure of orotidine 5'-phosphate decarboxylase from Plasmodium falciparum
分子名称: Orotidine-monophosphate-decarboxylase, PHOSPHATE ION
著者Liu, Y, Lau, W, Lew, J, Amani, M, Hui, R, Pai, E.F, Structural Genomics Consortium (SGC)
登録日2007-06-11
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of orotidine 5'-phosphate decarboxylase from Plasmodium falciparum.
To be Published
4CDJ
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BU of 4cdj by Molmil
Structure of ZNRF3 ectodomain
分子名称: 1,2-ETHANEDIOL, E3 UBIQUITIN-PROTEIN LIGASE ZNRF3, FORMIC ACID
著者Peng, W.C, de Lau, W, Madoori, P.K, Forneris, F, Granneman, J.C.M, Clevers, H, Gros, P.
登録日2013-11-01
公開日2014-01-08
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structures of Wnt-Antagonist Znrf3 and its Complex with R-Spondin 1 and Implications for Signaling.
Plos One, 8, 2013
4CDK
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Structure of ZNRF3-RSPO1
分子名称: E3 UBIQUITIN-PROTEIN LIGASE ZNRF3, R-SPONDIN-1
著者Peng, W.C, de Lau, W, Madoori, P.K, Forneris, F, Granneman, J.C.M, Clevers, H, Gros, P.
登録日2013-11-01
公開日2014-01-08
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of Wnt-Antagonist Znrf3 and its Complex with R-Spondin 1 and Implications for Signaling.
Plos One, 8, 2013
4BSS
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Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in P21 crystal form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, ...
著者Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P.
登録日2013-06-11
公開日2013-06-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
4BSU
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Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in C2 crystal form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, ...
著者Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P.
登録日2013-06-11
公開日2013-06-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
4BSP
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BU of 4bsp by Molmil
Crystal structure of R-spondin 1 (Fu1Fu2) - Holmium soak
分子名称: HOLMIUM ATOM, R-SPONDIN-1, SULFATE ION
著者Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P.
登録日2013-06-11
公開日2013-06-19
最終更新日2013-07-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
4BSR
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BU of 4bsr by Molmil
Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in P22121 crystal form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, ...
著者Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P.
登録日2013-06-11
公開日2013-06-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
4BSO
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BU of 4bso by Molmil
Crystal structure of R-spondin 1 (Fu1Fu2) - Native
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, R-SPONDIN-1
著者Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P.
登録日2013-06-11
公開日2013-06-19
最終更新日2013-07-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
4BST
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BU of 4bst by Molmil
Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in P6122 crystal form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, R-SPONDIN-1, ...
著者Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P.
登録日2013-06-11
公開日2013-06-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
3BPW
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BU of 3bpw by Molmil
Crystal Structure of P. falciparum Orotidine 5'-monophosphate Decarboxylase Complexed with XMP
分子名称: DI(HYDROXYETHYL)ETHER, Orotidine 5'-phosphate decarboxylase, PHOSPHATE ION, ...
著者Liu, Y, Lau, W, Pai, E.F.
登録日2007-12-19
公開日2008-11-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of P. falciparum Orotidine 5'-monophosphate Decarboxylase Complexed with XMP
To be Published
2QAF
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Crystal structure of Plasmodium falciparum orotidine 5'-phosphate decarboxylase covalently modified by 6-iodo-UMP
分子名称: Orotidine 5' monophosphate decarboxylase, SULFATE ION, URIDINE-5'-MONOPHOSPHATE
著者Liu, Y, Lau, W, Bello, A.M, Kotra, L.P, Hui, R, Pai, E.F.
登録日2007-06-15
公開日2008-04-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure-activity relationships of C6-uridine derivatives targeting plasmodia orotidine monophosphate decarboxylase
J.Med.Chem., 51, 2008
3BAR
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BU of 3bar by Molmil
Crystal structure of Plasmodium falciparum orotidine 5'-phosphate decarboxylase covalently modified by 6-azido-UMP
分子名称: Orotidine 5'-phosphate decarboxylase, URIDINE-5'-MONOPHOSPHATE
著者Liu, Y, Bello, A.M, Poduch, E, Lau, W, Kotra, L.P, Pai, E.F.
登録日2007-11-08
公開日2008-01-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure-Activity Relationships of C6-Uridine Derivatives Targeting Plasmodia Orotidine Monophosphate Decarboxylase.
J.Med.Chem., 51, 2008
2UX1
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BU of 2ux1 by Molmil
Identification of two zinc-binding sites in the Streptococcus suis Dpr protein
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ...
著者Havukainen, H, Kauko, A, Pulliainen, A.T, Haataja, S, Meyer-Klaucke, W, Finne, J, Papageorgiou, A.C.
登録日2007-03-26
公開日2008-05-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis of the Zinc- and Terbium-Mediated Inhibition of Ferroxidase Activity in Dps Ferritin- Like Proteins.
Protein Sci., 17, 2008
2L62
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Protein and metal cluster structure of the wheat metallothionein domain g-Ec-1. The second part of the puzzle.
分子名称: EC protein I/II, ZINC ION
著者Loebus, J, Peroza, E.A, Bluethgen, N, Fox, T, Meyer-Klaucke, W, Zerbe, O, Freisinger, E.
登録日2010-11-12
公開日2011-05-25
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Protein and metal cluster structure of the wheat metallothionein domain gamma-E(c)-1: the second part of the puzzle.
J.Biol.Inorg.Chem., 16, 2011
2CBN
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Crystal structure of ZipD from Escherichia coli
分子名称: RIBONUCLEASE Z, ZINC ION
著者Pohl, E, Meyer-Klaucke, W, Kostelecky, B.
登録日2006-01-06
公開日2006-02-15
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Crystal Structure of the Zinc Phosphodiesterase from Escherichia Coli Provides Insight Into Function and Cooperativity of Trnase Z-Family Proteins.
J.Bacteriol., 188, 2006
2L61
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Protein and metal cluster structure of the wheat metallothionein domain g-Ec-1. The second part of the puzzle.
分子名称: CADMIUM ION, EC protein I/II
著者Loebus, J, Peroza, E.A, Bluethgen, N, Fox, T, Meyer-Klaucke, W, Zerbe, O, Freisinger, E.
登録日2010-11-12
公開日2011-05-25
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Protein and metal cluster structure of the wheat metallothionein domain gamma-E(c)-1: the second part of the puzzle.
J.Biol.Inorg.Chem., 16, 2011

 

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