4U3X
| Structure of a human VH antibody domain binding to the cleft of hen egg lysozyme | Descriptor: | 1,2-ETHANEDIOL, Human VH domain antibody, Lysozyme C | Authors: | Rouet, R, Langley, D.B, Christ, D. | Deposit date: | 2014-07-23 | Release date: | 2015-03-11 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Fully Human VH Single Domains That Rival the Stability and Cleft Recognition of Camelid Antibodies J.Biol.Chem., 290, 2015
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3MMK
| The structural basis for partial redundancy in a class of transcription factors, the lim-homeodomain proteins, in neural cell type specification | Descriptor: | CHLORIDE ION, Fusion of LIM/homeobox protein Lhx4, linker, ... | Authors: | Gadd, M.S, Langley, D.B, Guss, J.M, Matthews, J.M. | Deposit date: | 2010-04-20 | Release date: | 2011-07-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.157 Å) | Cite: | The structural basis for partial redundancy in a class of transcription factors, the lim-homeodomain proteins, in neural cell type specification. J.Biol.Chem., 2011
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4YKB
| Structure of GUN4 from Chlamydomonas reinhardtii | Descriptor: | Tetrapyrrole-binding protein | Authors: | Tabriz, S.T, Langley, D.B, Willows, R.D, Duff, A.P, Harrop, S.J. | Deposit date: | 2015-03-04 | Release date: | 2015-08-12 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structure of GUN4 from Chlamydomonas reinhardtii. Acta Crystallogr F Struct Biol Commun, 71, 2015
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3UPC
| A general strategy for the generation of human antibody variable domains with increased aggregation resistance | Descriptor: | DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, TETRAETHYLENE GLYCOL, ... | Authors: | Dudgeon, K, Rouet, R, Kokmeijer, I, Langley, D.B, Christ, D. | Deposit date: | 2011-11-17 | Release date: | 2012-06-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | General strategy for the generation of human antibody variable domains with increased aggregation resistance Proc.Natl.Acad.Sci.USA, 109, 2012
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3UPA
| A general strategy for the generation of human antibody variable domains with increased aggregation resistance | Descriptor: | kappa light chain variable domain | Authors: | Dudgeon, K, Rouet, R, Kokmeijer, I, Langley, D.B, Christ, D. | Deposit date: | 2011-11-17 | Release date: | 2012-06-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | General strategy for the generation of human antibody variable domains with increased aggregation resistance Proc.Natl.Acad.Sci.USA, 109, 2012
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4PGJ
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1SII
| AGAO in covalent complex with the inhibitor NOBA ("4-(2-naphthyloxy)-2-butyn-1-amine") | Descriptor: | COPPER (II) ION, GLYCEROL, Phenylethylamine oxidase, ... | Authors: | Guss, J.M, Langley, D.B, Duff, A.P. | Deposit date: | 2004-02-29 | Release date: | 2004-09-07 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Differential Inhibition of Six Copper Amine Oxidases by a Family of 4-(Aryloxy)-2-butynamines: Evidence for a New Mode of Inactivation. Biochemistry, 43, 2004
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1SIH
| AGAO in covalent complex with the inhibitor MOBA ("4-(4-methylphenoxy)-2-butyn-1-amine") | Descriptor: | COPPER (II) ION, GLYCEROL, Phenylethylamine oxidase, ... | Authors: | Guss, J.M, Langley, D.B, Duff, A.P. | Deposit date: | 2004-02-29 | Release date: | 2004-09-07 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Differential Inhibition of Six Copper Amine Oxidases by a Family of 4-(Aryloxy)-2-butynamines: Evidence for a New Mode of Inactivation. Biochemistry, 43, 2004
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3FYR
| Crystal structure of the sporulation histidine kinase inhibitor Sda from Bacillus subtilis | Descriptor: | Sporulation inhibitor sda | Authors: | Jacques, D.A, Streamer, M, King, G.F, Guss, J.M, Trewhella, J, Langley, D.B. | Deposit date: | 2009-01-23 | Release date: | 2009-06-23 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structure of the sporulation histidine kinase inhibitor Sda from Bacillus subtilis and insights into its solution state Acta Crystallogr.,Sect.D, 65, 2009
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6MH2
| Structure of Herceptin Fab without antigen | Descriptor: | Herceptin Fab arm heavy chain, Herceptin Fab arm light chain | Authors: | Luthra, A, Langley, D.B, Christie, M, Christ, D. | Deposit date: | 2018-09-17 | Release date: | 2019-05-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Human Antibody Bispecifics through Phage Display Selection. Biochemistry, 58, 2019
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7T5O
| VFLIP Spike Trimer with GAR03 | Descriptor: | GAR03 Fab heavy chain, GAR03 Fab light chain, Spike glycoprotein | Authors: | Sobti, M, Stewart, A.G, Rouet, R, Langley, D.B. | Deposit date: | 2021-12-12 | Release date: | 2023-01-25 | Last modified: | 2023-08-09 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients. Nat Commun, 14, 2023
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3OEP
| Crystal structure of TTHA0988 in space group P43212 | Descriptor: | GLYCEROL, Putative uncharacterized protein TTHA0988, SULFATE ION | Authors: | Jacques, D.A, Langley, D.B, Trewhella, J, Guss, J.M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2010-08-13 | Release date: | 2010-11-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The structure of TTHA0988 from Thermus thermophilus, a KipI-KipA homologue incorrectly annotated as an allophanate hydrolase Acta Crystallogr.,Sect.D, 67, 2011
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3OVU
| Crystal Structure of Human Alpha-Haemoglobin Complexed with AHSP and the First NEAT Domain of IsdH from Staphylococcus aureus | Descriptor: | Alpha-hemoglobin-stabilizing protein, Hemoglobin subunit alpha, Iron-regulated surface determinant protein H, ... | Authors: | Jacques, D.A, Krishna Kumar, K, Caradoc-Davies, T.T, Langley, D.B, Mackay, J.P, Guss, J.M, Gell, D.A. | Deposit date: | 2010-09-17 | Release date: | 2011-09-21 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.83 Å) | Cite: | A new haem pocket structure in alpha-haemoglobin To be Published
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1WAR
| Recombinant Human Purple Acid Phosphatase expressed in Pichia Pastoris | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FE (III) ION, HUMAN PURPLE ACID PHOSPHATASE, ... | Authors: | Duff, A.P, Langley, D.B, Han, R, Averill, B.A, Freeman, H.C, Guss, J.M. | Deposit date: | 2004-10-28 | Release date: | 2005-07-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Crystal Structures of Recombinant Human Purple Acid Phosphatase with and without an Inhibitory Conformation of the Repression Loop. J.Mol.Biol., 351, 2005
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1W6C
| AGAO holoenzyme in a small cell, at 2.2 angstroms | Descriptor: | COPPER (II) ION, PHENYLETHYLAMINE OXIDASE, SODIUM ION | Authors: | Duff, A.P, Langley, D.B, Juda, G.A, Shepard, E.M, Dooley, D.M, Freeman, H.C, Guss, J.M. | Deposit date: | 2004-08-17 | Release date: | 2005-12-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Copper Containing Amine Oxidase from Arthrobacter Globiformis: Refinement at 1.55 And 2.20 A Resolution in Two Crystal Forms. Acta Crystallogr.,Sect.F, 62, 2006
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1W4N
| AGAO covalent complex with Tranylcypromine | Descriptor: | COPPER (II) ION, GLYCEROL, PHENYLETHYLAMINE OXIDASE, ... | Authors: | Duff, A.P, Trambaiolo, D.M, Langley, D.B, Juda, G.A, Shepard, E.M, Dooley, D.M, Freeman, H.C, Guss, J.M. | Deposit date: | 2004-07-27 | Release date: | 2005-12-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Complexes of the Copper-Containing Amine Oxidase from Arthrobacter Globiformis with the Inhibitors Benzylhydrazine and Tranylcypromine. Acta Crystallogr.,Sect.F, 64, 2008
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1W5Z
| AGAO covalent complex with Benzylhydrazine | Descriptor: | COPPER (II) ION, GLYCEROL, PHENYLETHYLAMINE OXIDASE, ... | Authors: | Duff, A.P, Trambaiolo, D.M, Langley, D.B, Juda, G.A, Shepard, E.M, Dooley, D.M, Freeman, H.C, Guss, J.M. | Deposit date: | 2004-08-11 | Release date: | 2005-12-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Complexes of the Copper-Containing Amine Oxidase from Arthrobacter Globiformis with the Inhibitors Benzylhydrazine and Tranylcypromine. Acta Crystallogr.,Sect.F, 64, 2008
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1W2Z
| PSAO and Xenon | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AMINE OXIDASE, COPPER CONTAINING, ... | Authors: | Duff, A.P, Trambaiolo, D.M, Cohen, A.E, Ellis, P.J, Juda, G.A, Shepard, E.M, Langley, D.B, Dooley, D.M, Freeman, H.C, Guss, J.M. | Deposit date: | 2004-07-11 | Release date: | 2004-11-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Using Xenon as a Probe for Dioxygen-Binding Sites in Copper Amine Oxidases. J.Mol.Biol., 344, 2004
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5VAS
| Pekin duck egg lysozyme isoform III (DEL-III), orthorhombic form | Descriptor: | GLYCEROL, Lysozyme, PHOSPHATE ION | Authors: | Christie, M, Christ, D, Langley, D.B. | Deposit date: | 2017-03-27 | Release date: | 2018-04-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural basis of antigen recognition: crystal structure of duck egg lysozyme. Acta Crystallogr D Struct Biol, 73, 2017
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