5JBX
| Crystal structure of LiuC in complex with coenzyme A and malonic acid | 分子名称: | 3-hydroxybutyryl-CoA dehydratase, COENZYME A, MALONATE ION | 著者 | Bock, T, Reichelt, J, Mueller, R, Blankenfeldt, W. | 登録日 | 2016-04-14 | 公開日 | 2016-06-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | The Structure of LiuC, a 3-Hydroxy-3-Methylglutaconyl CoA Dehydratase Involved in Isovaleryl-CoA Biosynthesis in Myxococcus xanthus, Reveals Insights into Specificity and Catalysis. Chembiochem, 17, 2016
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5K1S
| crystal structure of AibC | 分子名称: | Oxidoreductase, zinc-binding dehydrogenase family, ZINC ION | 著者 | Bock, T, Mueller, R, Blankenfeldt, W. | 登録日 | 2016-05-18 | 公開日 | 2016-08-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Crystal structure of AibC, a reductase involved in alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus. Acta Crystallogr.,Sect.F, 72, 2016
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5K7Z
| Crystal structure of AibR in complex with isovaleryl coenzyme A and operator DNA | 分子名称: | DNA (32-MER), Isovaleryl-coenzyme A, Transcriptional regulator, ... | 著者 | Bock, T, Volz, C, Mueller, R, Blankenfeldt, W. | 登録日 | 2016-05-27 | 公開日 | 2016-12-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | Crystal structure of AibR in complex with isovaleryl coenzyme A and operator DNA to be published
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5O16
| Crystal structure of bifunctional dehydratase-cyclase domain in ambruticin biosynthesis | 分子名称: | AmbC, SULFATE ION | 著者 | Sung, K.H, Berkhan, G, Hollmann, T, Wagner, L, Hahn, F, Blankenfeldt, W. | 登録日 | 2017-05-18 | 公開日 | 2017-11-08 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.745 Å) | 主引用文献 | Insights into the Dual Activity of a Bifunctional Dehydratase-Cyclase Domain. Angew. Chem. Int. Ed. Engl., 57, 2018
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5K7H
| Crystal structure of AibR in complex with the effector molecule isovaleryl coenzyme A | 分子名称: | CHLORIDE ION, Isovaleryl-coenzyme A, NICKEL (II) ION, ... | 著者 | Bock, T, Volz, C, Mueller, R, Blankenfeldt, W. | 登録日 | 2016-05-26 | 公開日 | 2016-12-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | The AibR-isovaleryl coenzyme A regulator and its DNA binding site - a model for the regulation of alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus. Nucleic Acids Res., 45, 2017
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5JBW
| Crystal structure of LiuC | 分子名称: | 3-hydroxybutyryl-CoA dehydratase | 著者 | Bock, T, Reichelt, J, Mueller, R, Blankenfeldt, W. | 登録日 | 2016-04-14 | 公開日 | 2016-06-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The Structure of LiuC, a 3-Hydroxy-3-Methylglutaconyl CoA Dehydratase Involved in Isovaleryl-CoA Biosynthesis in Myxococcus xanthus, Reveals Insights into Specificity and Catalysis. Chembiochem, 17, 2016
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4X8B
| Ergothioneine-biosynthetic sulfoxide synthase EgtB, apo form | 分子名称: | CALCIUM ION, CHLORIDE ION, FE (III) ION, ... | 著者 | Vit, A, Goncharenko, K.V, Blankenfeldt, W, Seebeck, F.P. | 登録日 | 2014-12-10 | 公開日 | 2015-01-28 | 最終更新日 | 2017-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of the Sulfoxide Synthase EgtB from the Ergothioneine Biosynthetic Pathway. Angew.Chem.Int.Ed.Engl., 54, 2015
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4X8D
| Ergothioneine-biosynthetic sulfoxide synthase EgtB in complex with N,N-dimethyl-histidine and gamma-glutamyl-cysteine | 分子名称: | CALCIUM ION, CHLORIDE ION, GAMMA-GLUTAMYLCYSTEINE, ... | 著者 | Vit, A, Goncharenko, K.V, Blankenfeldt, W, Seebeck, F.P. | 登録日 | 2014-12-10 | 公開日 | 2015-01-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structure of the Sulfoxide Synthase EgtB from the Ergothioneine Biosynthetic Pathway. Angew.Chem.Int.Ed.Engl., 54, 2015
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4X8E
| Ergothioneine-biosynthetic sulfoxide synthase EgtB in complex with N,N,N-trimethyl-histidine | 分子名称: | CALCIUM ION, CHLORIDE ION, FE (III) ION, ... | 著者 | Vit, A, Goncharenko, K.V, Blankenfeldt, W, Seebeck, F.P. | 登録日 | 2014-12-10 | 公開日 | 2015-01-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of the Sulfoxide Synthase EgtB from the Ergothioneine Biosynthetic Pathway. Angew.Chem.Int.Ed.Engl., 54, 2015
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5IWE
| E45Q mutant of phenazine biosynthesis protein PhzF in complex with (5R,6R)-6-azaniumyl-5-ethoxycyclohexa-1,3-diene-1-carboxylate | 分子名称: | (5R,6R)-6-azaniumyl-5-ethoxycyclohexa-1,3-diene-1-carboxylate, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... | 著者 | Diederich, C, Blankenfeldt, W. | 登録日 | 2016-03-22 | 公開日 | 2017-03-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Mechanisms and Specificity of Phenazine Biosynthesis Protein PhzF. Sci Rep, 7, 2017
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5K7F
| Crystal structure of apo AibR | 分子名称: | ACETATE ION, Transcriptional regulator, TetR family | 著者 | Bock, T, Volz, C, Mueller, R, Blankenfeldt, W. | 登録日 | 2016-05-26 | 公開日 | 2016-12-21 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The AibR-isovaleryl coenzyme A regulator and its DNA binding site - a model for the regulation of alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus. Nucleic Acids Res., 45, 2017
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4ZFL
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5O15
| Crystal structure of bifunctional dehydratase-cyclase domain in ambruticin biosynthesis | 分子名称: | AmbC, GLYCEROL | 著者 | Sung, K.H, Berkhan, G, Hollmann, T, Wagner, L, Hahn, F, Blankenfeldt, W. | 登録日 | 2017-05-18 | 公開日 | 2017-11-08 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.174 Å) | 主引用文献 | Insights into the Dual Activity of a Bifunctional Dehydratase-Cyclase Domain. Angew. Chem. Int. Ed. Engl., 57, 2018
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5O30
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3ZUO
| OMCI in complex with leukotriene B4 | 分子名称: | COMPLEMENT INHIBITOR, LEUKOTRIENE B4 | 著者 | Roversi, P, Maillet, I, Togbe, D, Couillin, I, Quesniaux, V.F.J, Teixeira, M, Ahmat, N, Lissina, O, Boland, W, Ploss, K, Caesar, J.J.E, Leonhartsberger, S, Ryffel, B, Lea, S.M, Nunn, M.A. | 登録日 | 2011-07-19 | 公開日 | 2012-08-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Bifunctional Lipocalin Ameliorates Murine Immune Complex-Induced Acute Lung Injury. J.Biol.Chem., 288, 2013
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3ZUI
| OMCI in complex with palmitoleic acid | 分子名称: | COMPLEMENT INHIBITOR, PALMITOLEIC ACID | 著者 | Roversi, P, Maillet, I, Togbe, D, Couillin, I, Quesniaux, V.F.J, Teixeira, M, Ahmat, N, Lissina, O, Boland, W, Ploss, K, Caesar, J.J.E, Leonhartsberger, S, Ryffel, B, Lea, S.M, Nunn, M.A. | 登録日 | 2011-07-19 | 公開日 | 2012-08-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Bifunctional Lipocalin Ameliorates Murine Immune Complex-Induced Acute Lung Injury. J.Biol.Chem., 288, 2013
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3B4O
| Crystal structure of phenazine biosynthesis protein PhzA/B from Burkholderia cepacia R18194, apo form | 分子名称: | ACETATE ION, Phenazine biosynthesis protein A/B | 著者 | Ahuja, E.G, Janning, P, Mentel, M, Graebsch, A, Breinbauer, R, Blankenfeldt, W. | 登録日 | 2007-10-24 | 公開日 | 2008-12-30 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | PhzA/B catalyzes the formation of the tricycle in phenazine biosynthesis. J.Am.Chem.Soc., 130, 2008
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5X9O
| Crystal structure of the BCL6 BTB domain in complex with Compound 1a | 分子名称: | 1,2-ETHANEDIOL, 5-[(2-chloranyl-4-nitro-phenyl)amino]-1,3-dihydrobenzimidazol-2-one, B-cell lymphoma 6 protein, ... | 著者 | Sogabe, S, Ida, K, Lane, W, Snell, G. | 登録日 | 2017-03-08 | 公開日 | 2017-08-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Discovery of a novel B-cell lymphoma 6 (BCL6)-corepressor interaction inhibitor by utilizing structure-based drug design Bioorg. Med. Chem., 25, 2017
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5X4N
| Crystal structure of the BCL6 BTB domain in complex with Compound 4 | 分子名称: | 1,2-ETHANEDIOL, 5-chloro-N4-phenylpyrimidine-2,4-diamine, B-cell lymphoma 6 protein | 著者 | Sogabe, S, Ida, K, Lane, W, Snell, G. | 登録日 | 2017-02-13 | 公開日 | 2017-05-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Discovery of a B-Cell Lymphoma 6 Protein-Protein Interaction Inhibitor by a Biophysics-Driven Fragment-Based Approach J. Med. Chem., 60, 2017
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5X4O
| Crystal structure of the BCL6 BTB domain in complex with Compound 5 | 分子名称: | B-cell lymphoma 6 protein, N-methyl-N-{3-[({2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]pyridin-2-yl}methanesulfonamide | 著者 | Sogabe, S, Ida, K, Lane, W, Snell, G. | 登録日 | 2017-02-13 | 公開日 | 2017-05-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Discovery of a B-Cell Lymphoma 6 Protein-Protein Interaction Inhibitor by a Biophysics-Driven Fragment-Based Approach J. Med. Chem., 60, 2017
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5X4Q
| Crystal structure of the BCL6 BTB domain in complex with Compound 7 | 分子名称: | 1,2-ETHANEDIOL, 5-[[5-chloranyl-2-(pyridin-3-ylmethylamino)pyrimidin-4-yl]amino]-1,3-dihydroindol-2-one, B-cell lymphoma 6 protein, ... | 著者 | Sogabe, S, Ida, K, Lane, W, Snell, G. | 登録日 | 2017-02-13 | 公開日 | 2017-05-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of a B-Cell Lymphoma 6 Protein-Protein Interaction Inhibitor by a Biophysics-Driven Fragment-Based Approach J. Med. Chem., 60, 2017
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5X9P
| Crystal structure of the BCL6 BTB domain in complex with Compound 5 | 分子名称: | 3-[[4-chloranyl-2-nitro-5-[(2-oxidanylidene-1,3-dihydrobenzimidazol-5-yl)amino]phenyl]amino]propanoic acid, B-cell lymphoma 6 protein | 著者 | Sogabe, S, Ida, K, Lane, W, Snell, G. | 登録日 | 2017-03-08 | 公開日 | 2017-08-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Discovery of a novel B-cell lymphoma 6 (BCL6)-corepressor interaction inhibitor by utilizing structure-based drug design Bioorg. Med. Chem., 25, 2017
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5X4M
| Crystal structure of the BCL6 BTB domain in complex with Compound 1 | 分子名称: | B-cell lymphoma 6 protein, N-phenyl-1,3,5-triazine-2,4-diamine | 著者 | Sogabe, S, Ida, K, Lane, W, Snell, G. | 登録日 | 2017-02-13 | 公開日 | 2017-05-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Discovery of a B-Cell Lymphoma 6 Protein-Protein Interaction Inhibitor by a Biophysics-Driven Fragment-Based Approach J. Med. Chem., 60, 2017
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7AL5
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7AL6
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