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5O15

Crystal structure of bifunctional dehydratase-cyclase domain in ambruticin biosynthesis

Summary for 5O15
Entry DOI10.2210/pdb5o15/pdb
DescriptorAmbC, GLYCEROL (3 entities in total)
Functional Keywordsbiocatalysis, cyclases, dehydratases, heterocycles, polyketides, double hotdog fold, lyase
Biological sourceSorangium cellulosum
Total number of polymer chains2
Total formula weight64366.31
Authors
Sung, K.H.,Berkhan, G.,Hollmann, T.,Wagner, L.,Hahn, F.,Blankenfeldt, W. (deposition date: 2017-05-18, release date: 2017-11-08, Last modification date: 2024-01-17)
Primary citationSung, K.H.,Berkhan, G.,Hollmann, T.,Wagner, L.,Blankenfeldt, W.,Hahn, F.
Insights into the Dual Activity of a Bifunctional Dehydratase-Cyclase Domain.
Angew. Chem. Int. Ed. Engl., 57:343-347, 2018
Cited by
PubMed: 29084363
DOI: 10.1002/anie.201707774
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.174 Å)
Structure validation

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