5KCR
 
 | | Cryo-EM structure of the Escherichia coli 70S ribosome in complex with antibiotic Avilamycin C, mRNA and P-site tRNA at 3.6A resolution | | 分子名称: | (2R,3S,4R,6S)-4-hydroxy-6-{[(2R,3aR,4R,4'R,5'S,6S,6'R,7aR)-4'-hydroxy-6-{[(2S,3R,4R,5S,6R)-3-hydroxy-2-{[(2R,3S,4S,5S,6S)-4-hydroxy-6-({(2R,3aS,3a'R,6S,6'R,7R,7'R,7aR,7a'R)-7'-hydroxy-7'-[(1S)-1-hydroxyethyl]-6'-methyl-7-[(2-methylpropanoyl)oxy]octahydro-4H-2,4'-spirobi[[1,3]dioxolo[4,5-c]pyran]-6-yl}oxy)-5-methoxy-2-(methoxymethyl)tetrahydro-2H-pyran-3-yl]oxy}-5-methoxy-6-methyltetrahydro-2H-pyran-4-yl]oxy}-4,6',7a-trimethyloctahydro-4H-spiro[1,3-dioxolo[4,5-c]pyran-2,2'-pyran]-5'-yl]oxy}-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate (non-preferred name), 16S Ribosomal RNA, 23S Ribosomal RNA, ... | | 著者 | Arenz, S, Juette, M.F, Graf, M, Nguyen, F, Huter, P, Polikanov, Y.S, Blanchard, S.C, Wilson, D.N. | | 登録日 | 2016-06-06 | | 公開日 | 2016-08-17 | | 最終更新日 | 2019-12-25 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome.
Proc.Natl.Acad.Sci.USA, 113, 2016
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1KK0
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5L3F
 | | LSD1-CoREST1 in complex with polymyxin B | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1A, Polmyxin B, ... | | 著者 | Speranzini, V, Rotili, D, Ciossani, G, Pilotto, S, Forgione, M, Lucidi, A, Forneris, F, Velankar, S, Mai, A, Mattevi, A. | | 登録日 | 2016-04-10 | | 公開日 | 2016-09-21 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features.
Sci Adv, 2, 2016
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1KK1
 | | Structure of the large gamma subunit of initiation factor eIF2 from Pyrococcus abyssi-G235D mutant complexed with GDPNP-Mg2+ | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ZINC ION, ... | | 著者 | Schmitt, E, Blanquet, S, Mechulam, Y. | | 登録日 | 2001-12-06 | | 公開日 | 2002-04-10 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors.
EMBO J., 21, 2002
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2KSP
 | | Mechanism for the selective interaction of C-terminal EH-domain proteins with specific NPF-containing partners | | 分子名称: | CALCIUM ION, EH domain-containing protein 1, MICAL L1 like peptide | | 著者 | Kieken, F, Sharma, M, Jovic, M, Giridharan, S.S, Naslavsky, N, Caplan, S, Sorgen, P.L. | | 登録日 | 2010-01-11 | | 公開日 | 2010-01-26 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mechanism for the selective interaction of C-terminal Eps15 homology domain proteins with specific Asn-Pro-Phe-containing partners.
J.Biol.Chem., 285, 2010
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1I3Y
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3U6X
 | | Phage TP901-1 baseplate tripod | | 分子名称: | BPP, BROMIDE ION, ORF48 | | 著者 | Veesler, D, Spinelli, S, Mahony, J, Lichiere, J, Blangy, S, Bricogne, G, Legrand, P, Ortiz-Lombardia, M, Campanacci, V.I, van Sinderen, D, Cambillau, C. | | 登録日 | 2011-10-13 | | 公開日 | 2012-07-04 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of the phage TP901-1 1.8 MDa baseplate suggests an alternative host adhesion mechanism.
Proc.Natl.Acad.Sci.USA, 109, 2012
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2J8O
 | | Structure of the immunoglobulin tandem repeat of titin A168-A169 | | 分子名称: | GLYCEROL, TITIN | | 著者 | Mueller, S, Lange, S, Kursula, I, Gautel, M, Wilmanns, M. | | 登録日 | 2006-10-26 | | 公開日 | 2007-08-21 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Rigid Conformation of an Immunoglobulin Domain Tandem Repeat in the A-Band of the Elastic Muscle Protein Titin
J.Mol.Biol., 371, 2007
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4R1H
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6B0D
 | | An E. coli DPS protein from ferritin superfamily | | 分子名称: | DNA protection during starvation protein, FORMIC ACID, SODIUM ION | | 著者 | Rui, W, Ruslan, S, Ronan, K, Adam, J.S. | | 登録日 | 2017-09-14 | | 公開日 | 2018-09-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | SIMBAD: a sequence-independent molecular-replacement pipeline.
Acta Crystallogr D Struct Biol, 74, 2018
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2J8H
 | | Structure of the immunoglobulin tandem repeat A168-A169 of titin | | 分子名称: | GLYCEROL, TITIN | | 著者 | Mueller, S, Lange, S, Kursula, I, Gautel, M, Wilmanns, M. | | 登録日 | 2006-10-25 | | 公開日 | 2007-08-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Rigid Conformation of an Immunoglobulin Domain Tandem Repeat in the A-Band of the Elastic Muscle Protein Titin
J.Mol.Biol., 371, 2007
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6HC6
 | | The structure of BSAP, a zinc aminopeptidase from Bacillus subtilis | | 分子名称: | ACETATE ION, Aminopeptidase YwaD, GLYCEROL, ... | | 著者 | Rogoulenko, E, Lansky, S, Faygenboim, R, Cohen, T, Alhadeff, R, Shoham, Y, Shoham, G. | | 登録日 | 2018-08-14 | | 公開日 | 2019-08-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | To be published
To Be Published
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3IP5
 | | Structure of Atu2422-GABA receptor in complex with alanine | | 分子名称: | ABC transporter, substrate binding protein (Amino acid), ALANINE, ... | | 著者 | Morera, S, Planamente, S, Vigouroux, A. | | 登録日 | 2009-08-17 | | 公開日 | 2010-07-14 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | A conserved mechanism of GABA binding and antagonism is revealed by structure-function analysis of the periplasmic binding protein Atu2422 in Agrobacterium tumefaciens.
J.Biol.Chem., 285, 2010
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4JI2
 | | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | | 分子名称: | 16S rRNA, MAGNESIUM ION, RIBOSOMAL PROTEIN S10, ... | | 著者 | Demirci, H, Wang, L, Murphy IV, F, Murphy, E, Carr, J, Blanchard, S, Jogl, G, Dahlberg, A.E, Gregory, S.T. | | 登録日 | 2013-03-05 | | 公開日 | 2013-11-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.64 Å) | | 主引用文献 | The central role of protein S12 in organizing the structure of the decoding site of the ribosome.
Rna, 19, 2013
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3IP7
 | | Structure of Atu2422-GABA receptor in complex with valine | | 分子名称: | ABC transporter, substrate binding protein (Amino acid), CALCIUM ION, ... | | 著者 | Morera, S, Planamente, S, Vigouroux, A. | | 登録日 | 2009-08-17 | | 公開日 | 2010-07-14 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | A conserved mechanism of GABA binding and antagonism is revealed by structure-function analysis of the periplasmic binding protein Atu2422 in Agrobacterium tumefaciens.
J.Biol.Chem., 285, 2010
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3IP6
 | | Structure of Atu2422-GABA receptor in complex with proline | | 分子名称: | ABC transporter, substrate binding protein (Amino acid), PROLINE, ... | | 著者 | Morera, S, Planamente, S, Vigouroux, A. | | 登録日 | 2009-08-17 | | 公開日 | 2010-07-14 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | A conserved mechanism of GABA binding and antagonism is revealed by structure-function analysis of the periplasmic binding protein Atu2422 in Agrobacterium tumefaciens.
J.Biol.Chem., 285, 2010
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3IPC
 | | Structure of ATU2422-GABA F77A mutant receptor in complex with leucine | | 分子名称: | ABC transporter, substrate binding protein (Amino acid), LEUCINE, ... | | 著者 | Morera, S, Planamente, S, Vigouroux, A. | | 登録日 | 2009-08-17 | | 公開日 | 2010-07-14 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | A conserved mechanism of GABA binding and antagonism is revealed by structure-function analysis of the periplasmic binding protein Atu2422 in Agrobacterium tumefaciens.
J.Biol.Chem., 285, 2010
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4RGP
 | | Crystal Structure of Uncharacterized CRISPR/Cas System-associated Protein Csm6 from Streptococcus mutans | | 分子名称: | CALCIUM ION, Csm6_III-A, GLYCEROL, ... | | 著者 | Kim, Y, Li, H, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2014-09-30 | | 公開日 | 2014-12-24 | | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | | 主引用文献 | Crystal Structure of Uncharacterized CRISPR/Cas System-associated Protein Csm6 from Streptococcus mutans
To be Published
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6Q2B
 | | Crystal Structure of Putative MarR Family Transcriptional Regulator from Listeria monocytogenes complexed with 26mer DNA | | 分子名称: | ACETIC ACID, DNA (26-MER), MarR family transcriptional regulator | | 著者 | Kim, Y, Tesar, C, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2019-08-07 | | 公開日 | 2019-08-21 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | Crystal Structure of Putative MarR Family Transcriptional Regulator from Listeria monocytogenes complexed with 26mer DNA.
To Be Published
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3IPA
 | | Structure of ATU2422-GABA receptor in complex with alanine | | 分子名称: | ABC transporter, substrate binding protein (Amino acid), ALANINE, ... | | 著者 | Morera, S, Planamente, S, Vigouroux, A. | | 登録日 | 2009-08-17 | | 公開日 | 2010-07-14 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | A conserved mechanism of GABA binding and antagonism is revealed by structure-function analysis of the periplasmic binding protein Atu2422 in Agrobacterium tumefaciens.
J.Biol.Chem., 285, 2010
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6GZ4
 | | tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis, Translocation-intermediate-POST-2 (TI-POST-2) | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | | 著者 | Flis, J, Holm, M, Rundlet, E.J, Loerke, J, Hilal, T, Dabrowski, M, Buerger, J, Mielke, T, Blanchard, S.C, Spahn, C.M.T, Budkevich, T.V. | | 登録日 | 2018-07-03 | | 公開日 | 2018-12-05 | | 最終更新日 | 2022-03-30 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis.
Cell Rep, 25, 2018
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6FBU
 | | Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli (E2Q) in complex with AP-site containing DNA substrate | | 分子名称: | ACETATE ION, DNA (5'-D(P*CP*CP*AP*GP*GP*AP*(PED)P*GP*AP*AP*GP*CP*C)-3'), DNA (5'-D(P*GP*GP*CP*TP*TP*CP*AP*TP*CP*CP*TP*G)-3'), ... | | 著者 | Pomyalov, S, Lansky, S, Golan, G, Zharkov, D.O, Grollman, A.P, Shoham, G. | | 登録日 | 2017-12-19 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli (E2Q) in complex with AP-site containing DNA substrate
To Be Published
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3IP9
 | | Structure of Atu2422-GABA receptor in complex with GABA | | 分子名称: | ABC transporter, substrate binding protein (Amino acid), GAMMA-AMINO-BUTANOIC ACID, ... | | 著者 | Morera, S, Planamente, S, Vigouroux, A. | | 登録日 | 2009-08-17 | | 公開日 | 2010-07-14 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A conserved mechanism of GABA binding and antagonism is revealed by structure-function analysis of the periplasmic binding protein Atu2422 in Agrobacterium tumefaciens.
J.Biol.Chem., 285, 2010
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2K4I
 | | Solution structure of HIV-2 myrMA bound to di-C4-PI(4,5)P2 | | 分子名称: | (2R)-3-{[(R)-HYDROXY{[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIHYDROXY-4,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}PROPANE-1,2-DIYL DIBUTANOATE, HIV-2 myristoylated matrix protein, MYRISTIC ACID | | 著者 | Saad, J.S, Ablan, S.D, Ghanam, R.H, Kim, A, Andrews, K, Nagashima, K, Freed, E.O, Summers, M.F. | | 登録日 | 2008-06-08 | | 公開日 | 2008-08-12 | | 最終更新日 | 2014-01-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the myristylated human immunodeficiency virus type 2 matrix protein and the role of phosphatidylinositol-(4,5)-bisphosphate in membrane targeting.
J.Mol.Biol., 382, 2008
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6XUI
 | | Crystal structure of human phosphoglucose isomerase in complex with inhibitor | | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 5-PHOSPHOARABINONIC ACID, GLYCEROL, ... | | 著者 | Li de la Sierra-Gallay, I, Ahmad, L, Plancqueel, S, van Tilbeurgh, H, Salmon, L. | | 登録日 | 2020-01-20 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Novel N-substituted 5-phosphate-d-arabinonamide derivatives as strong inhibitors of phosphoglucose isomerases: Synthesis, structure-activity relationship and crystallographic studies.
Bioorg.Chem., 102, 2020
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