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PDB: 9 件

7B5D
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BU of 7b5d by Molmil
Structure of calcium-free mTMEM16A(ac)-I551A chloride channel at 3.3 A resolution
分子名称: Anoctamin-1
著者Lam, A.K.M, Rheinberger, J, Paulino, C, Dutzler, R.
登録日2020-12-03
公開日2021-02-10
最終更新日2021-02-17
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Gating the pore of the calcium-activated chloride channel TMEM16A.
Nat Commun, 12, 2021
7B5E
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BU of 7b5e by Molmil
Structure of calcium-bound mTMEM16A(ac)-I551A chloride channel at 4.1 A resolution
分子名称: Anoctamin-1, CALCIUM ION
著者Lam, A.K.M, Rheinberger, J, Paulino, C, Dutzler, R.
登録日2020-12-03
公開日2021-02-10
最終更新日2021-02-17
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Gating the pore of the calcium-activated chloride channel TMEM16A.
Nat Commun, 12, 2021
7B5C
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BU of 7b5c by Molmil
Structure of calcium-bound mTMEM16A(ac) chloride channel at 3.7 A resolution
分子名称: Anoctamin-1, CALCIUM ION
著者Lam, A.K.M, Rheinberger, J, Paulino, C, Dutzler, R.
登録日2020-12-03
公開日2021-02-10
最終更新日2021-02-17
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Gating the pore of the calcium-activated chloride channel TMEM16A.
Nat Commun, 12, 2021
7ZK3
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BU of 7zk3 by Molmil
Structure of 1PBC- and calcium-bound mTMEM16A(ac) chloride channel at 2.85 A resolution
分子名称: 1-Hydroxy-3-(trifluoromethyl)pyrido[1,2-a]benzimidazole-4-carbonitrile, Anoctamin-1, CALCIUM ION
著者Lam, A.K.M, Rutz, S, Dutzler, R.
登録日2022-04-12
公開日2022-05-25
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献Inhibition mechanism of the chloride channel TMEM16A by the pore blocker 1PBC.
Nat Commun, 13, 2022
8QZC
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BU of 8qzc by Molmil
Structure of calcium-bound mTMEM16A(ac)-L647V/I733V chloride channel at 3.29 A resolution
分子名称: Anoctamin-1, CALCIUM ION
著者Lam, A.K.M, Dutzler, R.
登録日2023-10-26
公開日2023-12-06
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Mechanistic basis of ligand efficacy in the calcium-activated chloride channel TMEM16A.
Embo J., 42, 2023
6FNW
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BU of 6fnw by Molmil
Structure of a volume-regulated anion channel of the LRRC8 family
分子名称: 1,2-ETHANEDIOL, Volume-regulated anion channel subunit LRRC8A
著者Deneka, D, Sawicka, M, Lam, A.K.M, Paulino, C, Dutzler, R.
登録日2018-02-05
公開日2018-05-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of a volume-regulated anion channel of the LRRC8 family.
Nature, 558, 2018
6G9L
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BU of 6g9l by Molmil
Structure of homomeric mLRRC8A volume-regulated anion channel at 5.01 A resolution
分子名称: Volume-regulated anion channel subunit LRRC8A
著者Sawicka, M, Deneka, D, Lam, A.K.M, Paulino, C, Dutzler, R.
登録日2018-04-11
公開日2018-05-16
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (5.01 Å)
主引用文献Structure of a volume-regulated anion channel of the LRRC8 family.
Nature, 558, 2018
6G8Z
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BU of 6g8z by Molmil
Structure of the pore domain of homomeric mLRRC8A volume-regulated anion channel at 3.66 A resolution
分子名称: Volume-regulated anion channel subunit LRRC8A
著者Sawicka, M, Deneka, D, Lam, A.K.M, Paulino, C, Dutzler, R.
登録日2018-04-10
公開日2018-05-16
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献Structure of a volume-regulated anion channel of the LRRC8 family.
Nature, 558, 2018
6G9O
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BU of 6g9o by Molmil
Structure of full-length homomeric mLRRC8A volume-regulated anion channel at 4.25 A resolution
分子名称: Volume-regulated anion channel subunit LRRC8A
著者Sawicka, M, Deneka, D, Lam, A.K.M, Paulino, C, Dutzler, R.
登録日2018-04-11
公開日2018-05-16
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (4.25 Å)
主引用文献Structure of a volume-regulated anion channel of the LRRC8 family.
Nature, 558, 2018

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件を2024-08-28に公開中

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