1NIH
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7PCR
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![BU of 7pcr by Molmil](/molmil-images/mine/7pcr) | Helicobacter pylori RNase J | Descriptor: | Ribonuclease J | Authors: | Luisi, B.F, Pei, X.Y. | Deposit date: | 2021-08-03 | Release date: | 2022-05-25 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Acetylation regulates the oligomerization state and activity of RNase J, the Helicobacter pylori major ribonuclease. Nat Commun, 14, 2023
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1GLU
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![BU of 1glu by Molmil](/molmil-images/mine/1glu) | CRYSTALLOGRAPHIC ANALYSIS OF THE INTERACTION OF THE GLUCOCORTICOID RECEPTOR WITH DNA | Descriptor: | DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*TP*CP*GP*AP*TP*GP*TP*TP*C P*TP*G)-3'), PROTEIN (GLUCOCORTICOID RECEPTOR), ZINC ION | Authors: | Luisi, B.F, Xu, W.X, Otwinowski, Z, Freedman, L.P, Yamamoto, K.R, Sigler, P.B. | Deposit date: | 1992-08-30 | Release date: | 1994-01-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA. Nature, 352, 1991
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1R4O
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![BU of 1r4o by Molmil](/molmil-images/mine/1r4o) | Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA | Descriptor: | 5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*TP*CP*GP*AP*TP*GP*TP*TP*CP*TP*G)-3', Glucocorticoid receptor, ZINC ION | Authors: | Luisi, B.F, Xu, W.X, Otwinowski, Z, Freedman, L.P, Yamamoto, K.R, Sigler, P.B. | Deposit date: | 2003-10-07 | Release date: | 2003-10-21 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystallographic Analysis of the Interaction of The Glucocorticoid Receptor with DNA Nature, 352, 1991
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1R4R
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![BU of 1r4r by Molmil](/molmil-images/mine/1r4r) | Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA | Descriptor: | 5'-D(*CP*TP*GP*AP*GP*AP*AP*CP*AP*TP*CP*AP*TP*GP*TP*TP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*AP*AP*CP*AP*TP*GP*AP*TP*GP*TP*TP*CP*TP*CP*A)-3', Glucocorticoid receptor, ... | Authors: | Luisi, B.F, Xu, W.X, Otwinowski, Z, Freedman, L.P, Yamamoto, K.R, Sigler, P.B. | Deposit date: | 2003-10-07 | Release date: | 2003-10-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystallographic Analysis of the Interaction of the Glucocorticoid Receptor with DNA Nature, 352, 1991
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5NQB
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5NQQ
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1COH
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1YC9
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![BU of 1yc9 by Molmil](/molmil-images/mine/1yc9) | The crystal structure of the outer membrane protein VceC from the bacterial pathogen Vibrio cholerae at 1.8 resolution | Descriptor: | MERCURY (II) ION, multidrug resistance protein, octyl beta-D-glucopyranoside | Authors: | Federici, L, Du, D, Walas, F, Matsumura, H, Fernandez-Recio, J, McKeegan, K.S, Borges-Walmsley, M.I, Luisi, B.F, Walmsley, A.R. | Deposit date: | 2004-12-22 | Release date: | 2005-03-01 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structure of the outer membrane protein VCEC from the bacterial pathogen vibrio cholerae at 1.8 A resolution J.Biol.Chem., 280, 2005
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4V2S
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![BU of 4v2s by Molmil](/molmil-images/mine/4v2s) | Crystal structure of Hfq in complex with the sRNA RydC | Descriptor: | RNA-BINDING PROTEIN HFQ, RYDC | Authors: | Dimastrogiovanni, D, Frohlich, K.S, Bruce, H.A, Bandyra, K.J, Hohensee, S, Vogel, J, Luisi, B.F. | Deposit date: | 2014-10-14 | Release date: | 2015-01-14 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.48 Å) | Cite: | Recognition of the small regulatory RNA RydC by the bacterial Hfq protein. Elife, 3, 2014
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6TNN
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![BU of 6tnn by Molmil](/molmil-images/mine/6tnn) | Mini-RNase III (Mini-III) bound to 50S ribosome with precursor 23S rRNA | Descriptor: | 50S ribosomal protein L10, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Oerum, S, Dendooven, T, Gilet, L, Catala, M, Degut, C, Trinquier, A, Barraud, P, Luisi, B, Condon, C, Tisne, C. | Deposit date: | 2019-12-09 | Release date: | 2020-09-30 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Structures of B. subtilis Maturation RNases Captured on 50S Ribosome with Pre-rRNAs. Mol.Cell, 80, 2020
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6O1L
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![BU of 6o1l by Molmil](/molmil-images/mine/6o1l) | Architectural principles for Hfq/Crc-mediated regulation of gene expression Hfq-Crc-amiE 2:3:2 complex | Descriptor: | Catabolite repression control protein, RNA (5'-R(*AP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*CP*AP*AP*GP*AP*GP*G)-3'), RNA-binding protein Hfq | Authors: | Pei, X.Y, Dendooven, T, Sonnleitner, E, Chen, S, Blasi, U, Luisi, B.F. | Deposit date: | 2019-02-20 | Release date: | 2019-03-13 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Architectural principles for Hfq/Crc-mediated regulation of gene expression. Elife, 8, 2019
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6O1K
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![BU of 6o1k by Molmil](/molmil-images/mine/6o1k) | Architectural principles for Hfq/Crc-mediated regulation of gene expression. Hfq-Crc-amiE 2:2:2 complex (core complex) | Descriptor: | Catabolite repression control protein, RNA (5'-R(*AP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*CP*AP*AP*GP*AP*GP*G)-3'), RNA-binding protein Hfq | Authors: | Pei, X.Y, Dendooven, T, Sonnleitner, E, Chen, S, Blasi, U, Luisi, B.F. | Deposit date: | 2019-02-20 | Release date: | 2019-03-13 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.13 Å) | Cite: | Architectural principles for Hfq/Crc-mediated regulation of gene expression Elife, 8, 2019
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6TMS
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![BU of 6tms by Molmil](/molmil-images/mine/6tms) | Crystal structure of a de novo designed hexameric helical-bundle protein | Descriptor: | SULFATE ION, a novel designed pore protein, affinity purification tag | Authors: | Xu, C, Pei, X.Y, Luisi, B.F, Baker, D. | Deposit date: | 2019-12-05 | Release date: | 2020-04-29 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Computational design of transmembrane pores. Nature, 585, 2020
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6O1M
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![BU of 6o1m by Molmil](/molmil-images/mine/6o1m) | Architectural principles for Hfq/Crc-mediated regulation of gene expression. Hfq-Crc-amiE 2:4:2 complex | Descriptor: | Catabolite repression control protein, RNA (5'-R(*AP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*CP*AP*AP*GP*AP*GP*G)-3'), RNA-binding protein Hfq | Authors: | Pei, X.Y, Dendooven, T, Sonnleitner, E, Chen, S, Blasi, U, Luisi, B.F. | Deposit date: | 2019-02-20 | Release date: | 2019-03-13 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Architectural principles for Hfq/Crc-mediated regulation of gene expression. Elife, 8, 2019
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6TJ1
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![BU of 6tj1 by Molmil](/molmil-images/mine/6tj1) | Crystal structure of a de novo designed hexameric helical-bundle protein | Descriptor: | De novo designed WSHC6, purification tag | Authors: | Xu, C, Pei, X.Y, Luisi, B.F, Baker, D. | Deposit date: | 2019-11-23 | Release date: | 2020-04-29 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Computational design of transmembrane pores. Nature, 585, 2020
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6G63
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![BU of 6g63 by Molmil](/molmil-images/mine/6g63) | RNase E in complex with sRNA RrpA | Descriptor: | RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), Ribonuclease E, URIDINE-5'-MONOPHOSPHATE, ... | Authors: | Bandyra, K.B, Luisi, B.F. | Deposit date: | 2018-03-31 | Release date: | 2018-10-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.95 Å) | Cite: | Substrate Recognition and Autoinhibition in the Central Ribonuclease RNase E. Mol. Cell, 72, 2018
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6TPQ
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![BU of 6tpq by Molmil](/molmil-images/mine/6tpq) | RNase M5 bound to 50S ribosome with precursor 5S rRNA | Descriptor: | 50S ribosomal protein L10, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Oerum, S, Dendooven, T, Gilet, L, Catala, M, Degut, C, Trinquier, A, Barraud, P, Luisi, B, Condon, C, Tisne, C. | Deposit date: | 2019-12-13 | Release date: | 2020-09-30 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Structures of B. subtilis Maturation RNases Captured on 50S Ribosome with Pre-rRNAs. Mol.Cell, 80, 2020
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7AU2
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![BU of 7au2 by Molmil](/molmil-images/mine/7au2) | Cryo-EM structure of human exostosin-like 3 (EXTL3) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Exostosin-like 3, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Wilson, L.F.L, Dendooven, T, Hardwick, S.W, Chirgadze, D.Y, Luisi, B.F, Logan, D.T, Mani, K, Dupree, P. | Deposit date: | 2020-11-02 | Release date: | 2022-05-18 | Last modified: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (2.43 Å) | Cite: | The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis. Nat Commun, 13, 2022
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7AUA
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![BU of 7aua by Molmil](/molmil-images/mine/7aua) | Cryo-EM structure of human exostosin-like 3 (EXTL3) in complex with UDP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Exostosin-like 3, MANGANESE (II) ION, ... | Authors: | Wilson, L.F.L, Dendooven, T, Hardwick, S.W, Chirgadze, D.Y, Luisi, B.F, Logan, D.T, Mani, K, Dupree, P. | Deposit date: | 2020-11-02 | Release date: | 2022-05-18 | Last modified: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis. Nat Commun, 13, 2022
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2JGD
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![BU of 2jgd by Molmil](/molmil-images/mine/2jgd) | E. COLI 2-oxoglutarate dehydrogenase (E1o) | Descriptor: | 2-OXOGLUTARATE DEHYDROGENASE E1 COMPONENT, ADENOSINE MONOPHOSPHATE | Authors: | Frank, R.A.W, Price, A.J, Northrop, F.D, Perham, R.N, Luisi, B.F. | Deposit date: | 2007-02-12 | Release date: | 2007-02-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of the E1 Component of the Escherichia Coli 2-Oxoglutarate Dehydrogenase Multienzyme Complex. J.Mol.Biol., 368, 2007
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8B0I
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![BU of 8b0i by Molmil](/molmil-images/mine/8b0i) | CryoEM structure of bacterial RapZ.GlmZ complex central to the control of cell envelope biogenesis | Descriptor: | GlmZ small regulatory RNA, RNase adapter protein RapZ | Authors: | Islam, M.S, Hardwick, H.W, Chirgadze, D.Y, Luisi, B.F. | Deposit date: | 2022-09-07 | Release date: | 2022-10-05 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (4.28 Å) | Cite: | Structure of a bacterial ribonucleoprotein complex central to the control of cell envelope biogenesis. Embo J., 42, 2023
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8B0J
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![BU of 8b0j by Molmil](/molmil-images/mine/8b0j) | CryoEM structure of bacterial RNaseE.RapZ.GlmZ complex central to the control of cell envelope biogenesis | Descriptor: | GlmZ small RNA, RNase adapter protein RapZ, Ribonuclease E | Authors: | Islam, M.S, Hardwick, H.W, Chirgadze, D.Y, Luisi, B.F. | Deposit date: | 2022-09-07 | Release date: | 2022-10-05 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.99 Å) | Cite: | Structure of a bacterial ribonucleoprotein complex central to the control of cell envelope biogenesis. Embo J., 42, 2023
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6HCK
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![BU of 6hck by Molmil](/molmil-images/mine/6hck) | The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with dipeptide Leu-Leu | Descriptor: | LEUCINE, Listeriolysin regulatory protein, SODIUM ION | Authors: | Grundstrom, C, Oelker, M, Krypotou, E, Scortti, M, Luisi, B.F, Vazquez-Boland, J, Sauer-Eriksson, A.E. | Deposit date: | 2018-08-15 | Release date: | 2019-02-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Control of Bacterial Virulence through the Peptide Signature of the Habitat. Cell Rep, 26, 2019
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6GWK
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![BU of 6gwk by Molmil](/molmil-images/mine/6gwk) | The crystal structure of Hfq from Caulobacter crescentus | Descriptor: | RNA-binding protein Hfq | Authors: | Santiago-Frangos, A, Frohlich, K.S, Jeliazkov, J.R, Gray, J.R, Luisi, B.F, Woodson, S.A, Hardwick, S.W. | Deposit date: | 2018-06-25 | Release date: | 2019-05-22 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Caulobacter crescentusHfq structure reveals a conserved mechanism of RNA annealing regulation. Proc.Natl.Acad.Sci.USA, 116, 2019
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