6WJJ
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![BU of 6wjj by Molmil](/molmil-images/mine/6wjj) | Anthrax octamer prechannel bound to full-length lethal factor | Descriptor: | CALCIUM ION, Lethal factor, Protective antigen, ... | Authors: | Zhou, K, Hardenbrook, N.J, Liu, S, Cui, Y.X, Krantz, B.A, Zhou, Z.H. | Deposit date: | 2020-04-13 | Release date: | 2020-12-16 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Atomic Structures of Anthrax Prechannel Bound with Full-Length Lethal and Edema Factors. Structure, 28, 2020
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6PSN
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![BU of 6psn by Molmil](/molmil-images/mine/6psn) | Anthrax toxin protective antigen channels bound to lethal factor | Descriptor: | CALCIUM ION, Lethal factor, Protective antigen | Authors: | Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A. | Deposit date: | 2019-07-12 | Release date: | 2020-03-04 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors. Nat Commun, 11, 2020
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1BH1
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![BU of 1bh1 by Molmil](/molmil-images/mine/1bh1) | STRUCTURAL STUDIES OF D-PRO MELITTIN, NMR, 20 STRUCTURES | Descriptor: | MELITTIN | Authors: | Barnham, K.J, Hewish, D, Werkmeister, J, Curtain, C, Kirkpatrick, A, Bartone, N, Liu, S.T, Norton, R, Rivett, D. | Deposit date: | 1998-06-11 | Release date: | 1999-01-06 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Structure and activity of D-Pro14 melittin. J.Protein Chem., 21, 2002
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4WUY
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![BU of 4wuy by Molmil](/molmil-images/mine/4wuy) | Crystal Structure of Protein Lysine Methyltransferase SMYD2 in complex with LLY-507, a Cell-Active, Potent and Selective Inhibitor | Descriptor: | 5-cyano-2'-{4-[2-(3-methyl-1H-indol-1-yl)ethyl]piperazin-1-yl}-N-[3-(pyrrolidin-1-yl)propyl]biphenyl-3-carboxamide, GLYCEROL, N-lysine methyltransferase SMYD2, ... | Authors: | Nguyen, H, Allali-Hassani, A, Antonysamy, S, Chang, S, Chen, L.H, Curtis, C, Emtage, S, Fan, L, Gheyi, T, Li, F, Liu, S, Martin, J.R, Mendel, D, Olsen, J.B, Pelletier, L, Shatseva, T, Wu, S, Zhang, F.F, Arrowsmith, C.H, Brown, P.J, Campbell, R.M, Garcia, B.A, Barsyte-Lovejoy, D, Mader, M, Vedadi, M. | Deposit date: | 2014-11-04 | Release date: | 2015-04-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2. J.Biol.Chem., 290, 2015
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6WO0
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![BU of 6wo0 by Molmil](/molmil-images/mine/6wo0) | human Artemis/SNM1C catalytic domain, crystal form 1 | Descriptor: | GLYCEROL, Protein artemis, ZINC ION | Authors: | Karim, F, Liu, S, Laciak, A.R, Volk, L, Rosenblum, M, Curtis, R, Huang, N, Carr, G, Zhu, G. | Deposit date: | 2020-04-23 | Release date: | 2020-07-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structural analysis of the catalytic domain of Artemis endonuclease/SNM1C reveals distinct structural features. J.Biol.Chem., 295, 2020
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6WNL
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![BU of 6wnl by Molmil](/molmil-images/mine/6wnl) | human Artemis/SNM1C catalytic domain, crystal form 2 | Descriptor: | Protein artemis, ZINC ION | Authors: | Karim, F, Liu, S, Laciak, A.R, Volk, L, Rosenblum, M, Curtis, R, Huang, N, Carr, G, Zhu, G. | Deposit date: | 2020-04-22 | Release date: | 2020-07-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Structural analysis of the catalytic domain of Artemis endonuclease/SNM1C reveals distinct structural features. J.Biol.Chem., 295, 2020
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4ZMU
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![BU of 4zmu by Molmil](/molmil-images/mine/4zmu) | Dcsbis, a diguanylate cyclase from Pseudomonas aeruginosa | Descriptor: | diguanylate cyclase | Authors: | Chen, Y, Liu, C, Liu, S, Chi, K, Gu, L. | Deposit date: | 2015-05-04 | Release date: | 2016-05-04 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.502 Å) | Cite: | crystal structure of Dcsbis from Pseudomonas aeruginosa To Be Published
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4ZMM
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![BU of 4zmm by Molmil](/molmil-images/mine/4zmm) | GGDEF domain of Dcsbis complexed with c-di-GMP | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), diguanylate cyclase | Authors: | Chen, Y, Liu, C, Liu, S, Chi, K, Gu, L. | Deposit date: | 2015-05-04 | Release date: | 2016-05-04 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.503 Å) | Cite: | Crystal structure of Dcsbis GGDEF domain complexed with c-di-GMP To Be Published
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1KBL
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![BU of 1kbl by Molmil](/molmil-images/mine/1kbl) | PYRUVATE PHOSPHATE DIKINASE | Descriptor: | AMMONIUM ION, PYRUVATE PHOSPHATE DIKINASE, SULFATE ION | Authors: | Herzberg, O, Chen, C.C, Liu, S. | Deposit date: | 2001-11-06 | Release date: | 2002-01-30 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Pyruvate site of pyruvate phosphate dikinase: crystal structure of the enzyme-phosphonopyruvate complex, and mutant analysis Biochemistry, 41, 2002
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1BUD
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![BU of 1bud by Molmil](/molmil-images/mine/1bud) | ACUTOLYSIN A FROM SNAKE VENOM OF AGKISTRODON ACUTUS AT PH 5.0 | Descriptor: | CALCIUM ION, PROTEIN (ACUTOLYSIN A), ZINC ION | Authors: | Gong, W, Zhu, X, Liu, S, Teng, M, Niu, L. | Deposit date: | 1998-09-03 | Release date: | 1999-09-07 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structures of acutolysin A, a three-disulfide hemorrhagic zinc metalloproteinase from the snake venom of Agkistrodon acutus. J.Mol.Biol., 283, 1998
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6F0P
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![BU of 6f0p by Molmil](/molmil-images/mine/6f0p) | Botulinum neurotoxin A4 Hc domain | Descriptor: | 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... | Authors: | Davies, J.R, Rees, J, Liu, S.M, Acharya, K.R. | Deposit date: | 2017-11-20 | Release date: | 2018-01-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | High resolution crystal structures of Clostridium botulinum neurotoxin A3 and A4 binding domains. J. Struct. Biol., 202, 2018
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1EPT
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![BU of 1ept by Molmil](/molmil-images/mine/1ept) | REFINED 1.8 ANGSTROMS RESOLUTION CRYSTAL STRUCTURE OF PORCINE EPSILON-TRYPSIN | Descriptor: | CALCIUM ION, PORCINE E-TRYPSIN | Authors: | Huang, Q, Wang, Z, Li, Y, Liu, S, Tang, Y. | Deposit date: | 1994-06-07 | Release date: | 1995-02-07 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Refined 1.8 A resolution crystal structure of the porcine epsilon-trypsin. Biochim.Biophys.Acta, 1209, 1994
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6F0O
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![BU of 6f0o by Molmil](/molmil-images/mine/6f0o) | Botulinum neurotoxin A3 Hc domain | Descriptor: | 1,2-ETHANEDIOL, Bontoxilysin A, PENTAETHYLENE GLYCOL, ... | Authors: | Davies, J.R, Liu, S.M, Acharya, K.R. | Deposit date: | 2017-11-20 | Release date: | 2018-01-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | High resolution crystal structures of Clostridium botulinum neurotoxin A3 and A4 binding domains. J. Struct. Biol., 202, 2018
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1BSW
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![BU of 1bsw by Molmil](/molmil-images/mine/1bsw) | ACUTOLYSIN A FROM SNAKE VENOM OF AGKISTRODON ACUTUS AT PH 7.5 | Descriptor: | CALCIUM ION, PROTEIN (ACUTOLYSIN A), ZINC ION | Authors: | Gong, W, Zhu, X, Liu, S, Teng, M, Niu, L. | Deposit date: | 1998-08-31 | Release date: | 1999-08-26 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structures of acutolysin A, a three-disulfide hemorrhagic zinc metalloproteinase from the snake venom of Agkistrodon acutus. J.Mol.Biol., 283, 1998
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3BM8
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1MRH
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![BU of 1mrh by Molmil](/molmil-images/mine/1mrh) | STUDIES ON CRYSTAL STRUCTURES ACTIVE CENTER GEOMETRY AND DEPURINE MECHANISM OF TWO RIBOSOME-INACTIVATING PROTEINS | Descriptor: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, ALPHA-MOMORCHARIN | Authors: | Huang, Q, Liu, S, Tang, Y, Jin, S, Wang, Y. | Deposit date: | 1994-07-01 | Release date: | 1995-02-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Studies on crystal structures, active-centre geometry and depurinating mechanism of two ribosome-inactivating proteins. Biochem.J., 309, 1995
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1MRK
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![BU of 1mrk by Molmil](/molmil-images/mine/1mrk) | STUDIES ON CRYSTAL STRUCTURES ACTIVE CENTER GEOMETRY AND DEPURINE MECHANISM OF TWO RIBOSOME-INACTIVATING PROTEINS | Descriptor: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, ALPHA-TRICHOSANTHIN | Authors: | Huang, Q, Liu, S, Tang, Y, Jin, S, Wang, Y. | Deposit date: | 1994-07-01 | Release date: | 1995-02-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Studies on crystal structures, active-centre geometry and depurinating mechanism of two ribosome-inactivating proteins. Biochem.J., 309, 1995
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1MRG
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![BU of 1mrg by Molmil](/molmil-images/mine/1mrg) | STUDIES ON CRYSTAL STRUCTURES ACTIVE CENTER GEOMETRY AND DEPURINE MECHANISM OF TWO RIBOSOME-INACTIVATING PROTEINS | Descriptor: | ADENOSINE, ALPHA-MOMORCHARIN | Authors: | Huang, Q, Liu, S, Tang, Y, Jin, S, Wang, Y. | Deposit date: | 1994-07-01 | Release date: | 1995-02-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Studies on crystal structures, active-centre geometry and depurinating mechanism of two ribosome-inactivating proteins. Biochem.J., 309, 1995
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1MRI
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![BU of 1mri by Molmil](/molmil-images/mine/1mri) | STUDIES ON CRYSTAL STRUCTURES ACTIVE CENTER GEOMETRY AND DEPURINE MECHANISM OF TWO RIBOSOME-INACTIVATING PROTEINS | Descriptor: | ALPHA-MOMORCHARIN | Authors: | Huang, Q, Liu, S, Tang, Y, Jin, S, Wang, Y. | Deposit date: | 1994-07-01 | Release date: | 1995-02-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Studies on crystal structures, active-centre geometry and depurinating mechanism of two ribosome-inactivating proteins. Biochem.J., 309, 1995
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3QIC
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![BU of 3qic by Molmil](/molmil-images/mine/3qic) | The structure of human glucokinase E339K mutation | Descriptor: | GLYCEROL, Glucokinase, alpha-D-glucopyranose | Authors: | Liu, Q, Liu, S, Liu, J. | Deposit date: | 2011-01-27 | Release date: | 2011-06-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of E339K mutated human glucokinase reveals changes in the ATP binding site. Febs Lett., 585, 2011
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4WHW
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![BU of 4whw by Molmil](/molmil-images/mine/4whw) | Direct photocapture of bromodomains using tropolone chemical probes | Descriptor: | 1,2-ETHANEDIOL, 2-methoxy-4-{1-[2-(morpholin-4-yl)ethyl]-2-(2-phenylethyl)-1H-benzimidazol-5-yl}cyclohepta-2,4,6-trien-1-one, Bromodomain-containing protein 4 | Authors: | Hett, E.C, Piatnitski Chekler, E.L, Basak, A, Bonin, P.D, Denny, R.A, Flick, A.C, Geoghegan, K.F, Liu, S, Pletcher, M.T, Robinson, R.P, Sahasrabudhe, P, Salter, S, Stock, I.A, Jones, L.H. | Deposit date: | 2014-09-23 | Release date: | 2015-10-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.345 Å) | Cite: | Direct photocapture of bromodomains using tropolone chemical probes To Be Published
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4B4A
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![BU of 4b4a by Molmil](/molmil-images/mine/4b4a) | Structure of the TatC core of the twin arginine protein translocation system | Descriptor: | Lauryl Maltose Neopentyl Glycol, SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATC | Authors: | Rollauer, S.E, Tarry, M.J, Jaaskelainen, M, Graham, J.E, Jaeger, F, Krehenbrink, M, Roversi, P, McDowell, M.A, Stansfeld, P.J, Johnson, S, Liu, S.M, Lukey, M.J, Marcoux, J, Robinson, C.V, Sansom, M.S, Palmer, T, Hogbom, M, Berks, B.C, Lea, S.M. | Deposit date: | 2012-07-30 | Release date: | 2012-12-05 | Last modified: | 2012-12-19 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structure of the Tatc Core of the Twin-Arginine Protein Transport System. Nature, 49, 2012
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3PFT
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![BU of 3pft by Molmil](/molmil-images/mine/3pft) | Crystal Structure of Untagged C54A Mutant Flavin Reductase (DszD) in Complex with FMN From Mycobacterium goodii | Descriptor: | FLAVIN MONONUCLEOTIDE, Flavin reductase | Authors: | Li, Q, Xu, P, Ma, C, Gu, L, Liu, X, Zhang, C, Li, N, Su, J, Li, B, Liu, S. | Deposit date: | 2010-10-29 | Release date: | 2011-11-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.601 Å) | Cite: | The flavin reductase DSZD from a desulfurizing mycobacterium goodii strain: systemic manipulation and investigation based on the crystal structure To be Published
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3HSM
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![BU of 3hsm by Molmil](/molmil-images/mine/3hsm) | Crystal structure of distal N-terminal beta-trefoil domain of Ryanodine Receptor type 1 | Descriptor: | Ryanodine receptor 1 | Authors: | Amador, F.J, Liu, S, Ishiyama, N, Plevin, M.J, Wilson, A, MacLennan, D.H, Ikura, M. | Deposit date: | 2009-06-10 | Release date: | 2009-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of type I ryanodine receptor amino-terminal beta-trefoil domain reveals a disease-associated mutation "hot spot" loop Proc.Natl.Acad.Sci.USA, 106, 2009
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4WXM
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![BU of 4wxm by Molmil](/molmil-images/mine/4wxm) | FleQ REC domain from Pseudomonas aeruginosa PAO1 | Descriptor: | Transcriptional regulator FleQ | Authors: | Su, T, Liu, S, Gu, L. | Deposit date: | 2014-11-14 | Release date: | 2015-09-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The REC domain mediated dimerization is critical for FleQ from Pseudomonas aeruginosa to function as a c-di-GMP receptor and flagella gene regulator J.Struct.Biol., 192, 2015
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