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PDB: 1782 件
8UMU
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BU of 8umu by Molmil
Atomic model of the human CTF18-RFC-PCNA binary complex in the four-subunit binding state (state 3)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Chromosome transmission fidelity protein 18 homolog, MAGNESIUM ION, ...
著者Wang, F, He, Q, Li, H.
登録日2023-10-18
公開日2024-05-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC.
Proc.Natl.Acad.Sci.USA, 121, 2024
8UMW
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BU of 8umw by Molmil
Atomic model of the human CTF18-RFC-PCNA-DNA ternary complex in the five-subunit binding state (state 4)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Chromosome transmission fidelity protein 18 homolog, DNA (20-MER), ...
著者Wang, F, He, Q, Li, H.
登録日2023-10-18
公開日2024-05-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC.
Proc.Natl.Acad.Sci.USA, 121, 2024
1D1V
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BU of 1d1v by Molmil
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH S-ETHYL-N-PHENYL-ISOTHIOUREA (H4B BOUND)
分子名称: 2-ETHYL-1-PHENYL-ISOTHIOUREA, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ...
著者Raman, C.S, Li, H, Martasek, P, Southan, G.J, Masters, B.S.S, Poulos, T.L.
登録日1999-09-21
公開日2001-07-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Implications for isoform-selective inhibitor design derived from the binding mode of bulky isothioureas to the heme domain of endothelial nitric-oxide synthase.
J.Biol.Chem., 276, 2001
6LLX
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BU of 6llx by Molmil
Discovery of A Dual Inhibitor of NQO1 and GSTP1 for Treating Malignant Glioblastoma
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, Glutathione S-transferase P
著者Ye, K, Li, H, Lei, K.C.
登録日2019-12-24
公開日2020-11-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.581 Å)
主引用文献Discovery of a dual inhibitor of NQO1 and GSTP1 for treating glioblastoma.
J Hematol Oncol, 13, 2020
1RS8
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BU of 1rs8 by Molmil
Bovine endothelial NOS heme domain with D-lysine-D-nitroarginine amide bound
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, CACODYLATE ION, ...
著者Flinspach, M, Li, H, Jamal, J, Yang, W, Huang, H, Silverman, R.B, Poulos, T.L.
登録日2003-12-09
公開日2004-06-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of the neuronal and endothelial nitric oxide synthase heme domain with D-nitroarginine-containing dipeptide inhibitors bound.
Biochemistry, 43, 2004
2R7A
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BU of 2r7a by Molmil
Crystal Structure of a Periplasmic Heme Binding Protein from Shigella dysenteriae
分子名称: Bacterial heme binding protein, PROTOPORPHYRIN IX CONTAINING FE
著者Ho, W.W, Li, H, Poulos, T.L.
登録日2007-09-07
公開日2007-10-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Holo- and apo-bound structures of bacterial periplasmic heme-binding proteins.
J.Biol.Chem., 282, 2007
1NDG
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BU of 1ndg by Molmil
Crystal structure of Fab fragment of antibody HyHEL-8 complexed with its antigen lysozyme
分子名称: ACETIC ACID, Lysozyme C, antibody kappa light chain, ...
著者Mariuzza, R.A, Li, Y, Li, H, Yang, F, Smith-Gill, S.J.
登録日2002-12-09
公開日2003-06-03
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献X-ray snapshots of the maturation of an antibody response to a protein antigen
Nat.Struct.Biol., 10, 2003
6MWY
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BU of 6mwy by Molmil
The Prp8 intein of Cryptococcus gattii
分子名称: Pre-mRNA-processing-splicing factor 8
著者Li, Z, Fu, B, Green, C.M, Lang, Y, Zhang, J, Oven, T.S, Li, X, Callahan, B.P, Chaturvedi, S, Belfort, M, Liao, G, Li, H.
登録日2018-10-30
公開日2019-11-06
最終更新日2020-05-20
実験手法X-RAY DIFFRACTION (2.594 Å)
主引用文献Cisplatin protects mice from challenge ofCryptococcus neoformansby targeting the Prp8 intein.
Emerg Microbes Infect, 8, 2019
1RS6
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BU of 1rs6 by Molmil
Rat neuronal NOS heme domain with D-lysine-D-nitroarginine amide bound
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, D-MANNITOL, ...
著者Flinspach, M, Li, H, Jamal, J, Yang, W, Huang, H, Silverman, R.B, Poulos, T.L.
登録日2003-12-09
公開日2004-05-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of the Neuronal and Endothelial Nitric Oxide Synthase Heme Domain with d-Nitroarginine-Containing Dipeptide Inhibitors Bound.
Biochemistry, 43, 2004
8EVT
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BU of 8evt by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES) refined against a composite map
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Zhao, Y, Rai, J, Li, H.
登録日2022-10-20
公開日2023-09-06
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
3MKA
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BU of 3mka by Molmil
Crystal Structure of Mycobacterium Tuberculosis Proteasome with propetide and an T1A mutation at beta-subunit
分子名称: Proteasome subunit alpha, Proteasome subunit beta
著者Li, D, Li, H.
登録日2010-04-14
公開日2010-05-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structural basis for the assembly and gate closure mechanisms of the Mycobacterium tuberculosis 20S proteasome.
Embo J., 29, 2010
1NDM
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BU of 1ndm by Molmil
Crystal structure of Fab fragment of antibody HyHEL-26 complexed with lysozyme
分子名称: Lysozyme C, antibody kappa light chain, immunoglobulin gamma 1 chain
著者Mariuzza, R.A, Li, Y, Li, H.
登録日2002-12-09
公開日2003-06-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-ray snapshots of the maturation of an antibody response to a protein antigen
Nat.Struct.Biol., 10, 2003
1SN1
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BU of 1sn1 by Molmil
STRUCTURE OF SCORPION NEUROTOXIN BMK M1
分子名称: PROTEIN (NEUROTOXIN BMK M1)
著者He, X.L, Li, H.M, Liu, X.Q, Zeng, Z.H, Wang, D.C.
登録日1998-11-12
公開日1999-11-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of two alpha-like scorpion toxins: non-proline cis peptide bonds and implications for new binding site selectivity on the sodium channel.
J.Mol.Biol., 292, 1999
5H3O
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BU of 5h3o by Molmil
Structure of a eukaryotic cyclic nucleotide-gated channel
分子名称: CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel, SODIUM ION
著者Li, M, Zhou, X, Wang, S, Michailidis, I, Gong, Y, Su, D, Li, H, Li, X, Yang, J.
登録日2016-10-26
公開日2017-01-25
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of a eukaryotic cyclic-nucleotide-gated channel.
Nature, 542, 2017
8EVP
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BU of 8evp by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), Structure I
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Zhao, Y, Rai, J, Li, H.
登録日2022-10-20
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (2.38 Å)
主引用文献Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EUB
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BU of 8eub by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2 and GDP, Structure I
分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S0-A, ...
著者Zhao, Y, Rai, J, Li, H.
登録日2022-10-18
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (2.52 Å)
主引用文献Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EVR
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BU of 8evr by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2, GDP, and sordarin, Structure II
分子名称: (1S,3S,3aR,4S,4aR,7R,7aR,8aS)-8a-{[(6-deoxy-4-O-methyl-alpha-D-altropyranosyl)oxy]methyl}-4-formyl-7-methyl-3-(propan-2-yl)decahydro-1,4-methano-s-indacene-3a(1H)-carboxylate, 18S rRNA, 25S rRNA, ...
著者Zhao, Y, Rai, J, Li, H.
登録日2022-10-20
公開日2023-09-06
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (2.87 Å)
主引用文献Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
6VSI
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BU of 6vsi by Molmil
Crystal structure of FKBP12 of Candida auris
分子名称: Peptidylprolyl isomerase, SULFATE ION
著者Li, Z, Li, H, Hernandez, G, LeMaster, D.
登録日2020-02-11
公開日2020-04-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Crystal structure and transient dimerization for the FKBP12 protein from the pathogenic fungus Candida auris.
Biochem.Biophys.Res.Commun., 525, 2020
6PTO
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BU of 6pto by Molmil
Structure of Ctf4 trimer in complex with three CMG helicases
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, DNA polymerase alpha-binding protein, ...
著者Yuan, Z, Georgescu, R, Bai, L, Santos, R, Donnell, M, Li, H.
登録日2019-07-16
公開日2019-11-20
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (7 Å)
主引用文献Ctf4 organizes sister replisomes and Pol alpha into a replication factory.
Elife, 8, 2019
8EVQ
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BU of 8evq by Molmil
Hypopseudouridylated Ribosome bound with TSV IRES, eEF2, GDP, and sordarin, Structure I
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Zhao, Y, Rai, J, Li, H.
登録日2022-10-20
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (2.72 Å)
主引用文献Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EVS
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BU of 8evs by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2 and GDP, Structure II
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Zhao, Y, Rai, J, Li, H.
登録日2022-10-20
公開日2023-09-06
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (2.62 Å)
主引用文献Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EWB
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BU of 8ewb by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2 and GDP, Structure III
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Zhao, Y, Rai, J, Li, H.
登録日2022-10-22
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (2.87 Å)
主引用文献Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EWC
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BU of 8ewc by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), Structure II
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Zhao, Y, Rai, J, Li, H.
登録日2022-10-22
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (2.45 Å)
主引用文献Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
3MFE
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BU of 3mfe by Molmil
Crystal Structure of Mycobacterium Tuberculosis Proteasome open-gate mutant with H0 movement
分子名称: Proteasome subunit alpha, Proteasome subunit beta
著者Li, D, Li, H.
登録日2010-04-02
公開日2010-06-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for the assembly and gate closure mechanisms of the Mycobacterium tuberculosis 20S proteasome.
Embo J., 2010
6AYF
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BU of 6ayf by Molmil
TRPML3/ML-SA1 complex at pH 7.4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Mucolipin-3
著者Zhou, X, Li, M, Su, D, Jia, Q, Li, H, Li, X, Yang, J.
登録日2017-09-08
公開日2017-11-08
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Cryo-EM structures of the human endolysosomal TRPML3 channel in three distinct states.
Nat. Struct. Mol. Biol., 24, 2017

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