1SN1
| STRUCTURE OF SCORPION NEUROTOXIN BMK M1 | 分子名称: | PROTEIN (NEUROTOXIN BMK M1) | 著者 | He, X.L, Li, H.M, Liu, X.Q, Zeng, Z.H, Wang, D.C. | 登録日 | 1998-11-12 | 公開日 | 1999-11-17 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structures of two alpha-like scorpion toxins: non-proline cis peptide bonds and implications for new binding site selectivity on the sodium channel. J.Mol.Biol., 292, 1999
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2RFB
| Crystal Structure of a Cytochrome P450 from the Thermoacidophilic Archaeon Picrophilus Torridus | 分子名称: | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | 著者 | Ho, W.W, Li, H, Poulos, T.L, Nishida, C.R, Ortiz de Montellano, P.R. | 登録日 | 2007-09-28 | 公開日 | 2008-01-29 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structure and Properties of CYP231A2 from the Thermoacidophilic Archaeon Picrophilus torridus. Biochemistry, 47, 2008
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8K5R
| CDK9/cyclin T1 in complex with KB-0742 | 分子名称: | (1S,3S)-N3-(5-pentan-3-ylpyrazolo[1,5-a]pyrimidin-7-yl)cyclopentane-1,3-diamine, Cyclin-T1, Cyclin-dependent kinase 9 | 著者 | Zhou, M, Li, H, Gao, H, Trotter, B.W, Freeman, D. | 登録日 | 2023-07-24 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.751 Å) | 主引用文献 | Discovery of KB-0742, a Potent, Selective, Orally Bioavailable Small Molecule Inhibitor of CDK9 for MYC-Dependent Cancers. J.Med.Chem., 66, 2023
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5XVA
| Crystal Structure of PAK4 in complex with inhibitor CZH216 | 分子名称: | ETHANOL, Serine/threonine-protein kinase PAK 4, [6-chloranyl-4-[(5-methyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl]-[(3R)-3-methylpiperazin-1-yl]methanone | 著者 | Zhao, F, Li, H. | 登録日 | 2017-06-27 | 公開日 | 2018-02-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.847 Å) | 主引用文献 | Structure-Based Design of 6-Chloro-4-aminoquinazoline-2-carboxamide Derivatives as Potent and Selective p21-Activated Kinase 4 (PAK4) Inhibitors. J. Med. Chem., 61, 2018
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3ER8
| Crystal structure of the heterodimeric vaccinia virus mRNA polyadenylate polymerase complex with two fragments of RNA | 分子名称: | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, Poly(A) polymerase catalytic subunit, RNA/DNA chimera 5'-D(CP*CP*)R(UP*UP*)D(C)-3', ... | 著者 | Li, C, Li, H, Zhou, S, Poulos, T.L, Gershon, P.D. | 登録日 | 2008-10-01 | 公開日 | 2009-06-16 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | 主引用文献 | Polymerase Translocation with Respect to Single-Stranded Nucleic Acid: Looping or Wrapping of Primer around a Poly(A) Polymerase Structure, 17, 2009
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5H3O
| Structure of a eukaryotic cyclic nucleotide-gated channel | 分子名称: | CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel, SODIUM ION | 著者 | Li, M, Zhou, X, Wang, S, Michailidis, I, Gong, Y, Su, D, Li, H, Li, X, Yang, J. | 登録日 | 2016-10-26 | 公開日 | 2017-01-25 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure of a eukaryotic cyclic-nucleotide-gated channel. Nature, 542, 2017
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5XVF
| Crystal Structure of PAK4 in complex with inhibitor CZH062 | 分子名称: | 2-(4-azanylpiperidin-1-yl)-6-chloranyl-N-(1-methylimidazol-4-yl)quinazolin-4-amine, Serine/threonine-protein kinase PAK 4 | 著者 | Zhao, F, Li, H. | 登録日 | 2017-06-27 | 公開日 | 2018-02-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.655 Å) | 主引用文献 | Structure-Based Design of 6-Chloro-4-aminoquinazoline-2-carboxamide Derivatives as Potent and Selective p21-Activated Kinase 4 (PAK4) Inhibitors. J. Med. Chem., 61, 2018
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6IG9
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8DVF
| T4 Bacteriophage primosome with single strand DNA, state 1 | 分子名称: | DNA (5'-D(P*GP*GP*CP*TP*G)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA primase, ... | 著者 | Feng, X, Li, H. | 登録日 | 2022-07-28 | 公開日 | 2023-06-14 | 最終更新日 | 2023-08-23 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of the T4 bacteriophage primosome assembly and primer synthesis. Nat Commun, 14, 2023
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8DVI
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8DTP
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8DW6
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8DUE
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8DUO
| DNA-free T4 Bacteriophage gp41 hexamer | 分子名称: | DnaB-like replicative helicase, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | 著者 | Feng, X, Li, H. | 登録日 | 2022-07-27 | 公開日 | 2023-06-14 | 最終更新日 | 2023-08-23 | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | 主引用文献 | Structural basis of the T4 bacteriophage primosome assembly and primer synthesis. Nat Commun, 14, 2023
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1ZBY
| High-Resolution Crystal Structure of Native (Resting) Cytochrome c Peroxidase (CcP) | 分子名称: | Cytochrome c peroxidase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Bonagura, C.A, Bhaskar, B, Shimizu, H, Li, H, Sundaramoorthy, M, McRee, D.E, Goodin, D.B, Poulos, T.L. | 登録日 | 2005-04-09 | 公開日 | 2005-05-03 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | High-resolution crystal structures and spectroscopy of native and compound I cytochrome c peroxidase Biochemistry, 42, 2003
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4N4I
| Crystal structure of the Bromo-PWWP of the mouse zinc finger MYND-type containing 11 isoform alpha in complex with histone H3.3K36me3 | 分子名称: | DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, Peptide from Histone H3.3, ... | 著者 | Li, Y, Ren, Y, Li, H. | 登録日 | 2013-10-08 | 公開日 | 2014-03-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | 主引用文献 | ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression Nature, 508, 2014
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1H65
| Crystal structure of pea Toc34 - a novel GTPase of the chloroplast protein translocon | 分子名称: | CHLOROPLAST OUTER ENVELOPE PROTEIN OEP34, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | 著者 | Sun, Y.J, Forouhar, F, Li, H.M, Tu, S.L, Kao, S, Shr, H.L, Chou, C.C, Hsiao, C.D. | 登録日 | 2001-06-06 | 公開日 | 2002-01-29 | 最終更新日 | 2019-06-12 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Pea Toc34 - a Novel Gtpase of the Chloroplast Protein Translocon Nat.Struct.Biol., 9, 2002
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1ZBZ
| High-Resolution Crystal Structure of Compound I intermediate of Cytochrome c Peroxidase (CcP) | 分子名称: | Cytochrome c peroxidase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Bonagura, C.A, Bhaskar, B, Shimizu, H, Li, H, Sundaramoorthy, M, McRee, D.E, Goodin, D.B, Poulos, T.L. | 登録日 | 2005-04-09 | 公開日 | 2005-05-03 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | 主引用文献 | High-resolution crystal structures and spectroscopy of native and compound I cytochrome c peroxidase Biochemistry, 42, 2003
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6J3O
| Crystal structure of the human PCAF bromodomain in complex with compound 12 | 分子名称: | 3-methyl-2-[[(3~{R})-1-methylpiperidin-3-yl]amino]-5~{H}-pyrrolo[3,2-d]pyrimidin-4-one, Histone acetyltransferase KAT2B | 著者 | Huang, L.Y, Li, H, Li, L.L, Niu, L, Seupel, R, Wu, C.Y, Li, G.B, Yu, Y.M, Brennan, P.E, Yang, S.Y. | 登録日 | 2019-01-05 | 公開日 | 2019-05-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain. J.Med.Chem., 62, 2019
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6VSI
| Crystal structure of FKBP12 of Candida auris | 分子名称: | Peptidylprolyl isomerase, SULFATE ION | 著者 | Li, Z, Li, H, Hernandez, G, LeMaster, D. | 登録日 | 2020-02-11 | 公開日 | 2020-04-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Crystal structure and transient dimerization for the FKBP12 protein from the pathogenic fungus Candida auris. Biochem.Biophys.Res.Commun., 525, 2020
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8G0Z
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4N4H
| Crystal structure of the Bromo-PWWP of the mouse zinc finger MYND-type containing 11 isoform alpha in complex with histone H3.1K36me3 | 分子名称: | DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, Peptide from Histone H3.1, ... | 著者 | Li, Y, Ren, Y, Li, H. | 登録日 | 2013-10-08 | 公開日 | 2014-03-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.302 Å) | 主引用文献 | ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression Nature, 508, 2014
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1SN4
| STRUCTURE OF SCORPION NEUROTOXIN BMK M4 | 分子名称: | ACETATE ION, PROTEIN (NEUROTOXIN BMK M4) | 著者 | He, X.L, Li, H.M, Liu, X.Q, Zeng, Z.H, Wang, D.C. | 登録日 | 1998-11-11 | 公開日 | 1999-11-17 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Crystal structures of two alpha-like scorpion toxins: non-proline cis peptide bonds and implications for new binding site selectivity on the sodium channel. J.Mol.Biol., 292, 1999
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2NNW
| Alternative conformations of Nop56/58-fibrillarin complex and implication for induced-fit assenly of box C/D RNPs | 分子名称: | Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase, NOP5/NOP56 related protein | 著者 | Oruganti, S, Zhang, Y, Terns, R, Terns, M.P, Li, H. | 登録日 | 2006-10-24 | 公開日 | 2007-08-21 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Alternative Conformations of the Archaeal Nop56/58-Fibrillarin Complex Imply Flexibility in Box C/D RNPs. J.Mol.Biol., 371, 2007
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4N4G
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