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PDB: 1778 件

6BS5
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Crystal structure of AMP-PNP-bound bacterial Get3-like A and B in Mycobacterium tuberculosis
分子名称: Anion transporter, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Li, H, Hu, K, Kovach, A.
登録日2017-12-01
公開日2019-05-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Characterization of Guided Entry of Tail-Anchored Proteins 3 Homologues in Mycobacterium tuberculosis.
J.Bacteriol., 201, 2019
3QZV
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BU of 3qzv by Molmil
Crystal Structure of BPTF PHD-linker-bromo in complex with histone H4K12ac peptide
分子名称: Histone H4, Nucleosome-remodeling factor subunit BPTF, ZINC ION
著者Li, H, Ruthenburg, A.J, Patel, D.J.
登録日2011-03-07
公開日2011-06-01
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions.
Cell(Cambridge,Mass.), 145, 2011
2D9U
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BU of 2d9u by Molmil
Solution structure of the Chromo domain of chromobox homolog 2 from human
分子名称: Chromobox protein homolog 2 (isoform 2)
著者Li, H, Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-13
公開日2007-01-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the Chromo domain of chromobox homolog 2 from human
To be Published
2CO9
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BU of 2co9 by Molmil
Solution structure of the HMG_box domain of thymus high mobility group box protein TOX from mouse
分子名称: thymus high mobility group box protein TOX
著者Li, H, Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-17
公開日2005-11-17
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the HMG_box domain of thymus high mobility group box protein TOX from mouse
To be Published
2COF
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BU of 2cof by Molmil
Solution structure of the C-terminal PH domain of hypothetical protein KIAA1914 from human
分子名称: Protein KIAA1914
著者Li, H, Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-17
公開日2005-11-17
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the C-terminal PH domain of hypothetical protein KIAA1914 from human
To be Published
3QZT
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BU of 3qzt by Molmil
Crystal Structure of BPTF bromo in complex with histone H4K16ac - Form II
分子名称: GLYCEROL, Histone H4, Nucleosome-remodeling factor subunit BPTF
著者Li, H, Ruthenburg, A.J, Patel, D.J.
登録日2011-03-07
公開日2011-06-01
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions.
Cell(Cambridge,Mass.), 145, 2011
2COA
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BU of 2coa by Molmil
Solution structure of the PH domain of protein kinase C, D2 type from human
分子名称: Protein kinase C, D2 type
著者Li, H, Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-17
公開日2005-11-17
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the PH domain of protein kinase C, D2 type from human
To be Published
2DHJ
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BU of 2dhj by Molmil
Solution structure of the PH domain of Rho GTPase activating protein 21 from human
分子名称: Rho GTPase activating protein 21
著者Li, H, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-03-24
公開日2006-09-24
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the PH domain of Rho GTPase activating protein 21 from human
To be Published
2DHK
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BU of 2dhk by Molmil
Solution structure of the PH domain of TBC1 domain family member 2 protein from human
分子名称: TBC1 domain family member 2
著者Li, H, Tochio, N, Koshiba, S, Harada, T, Watanabe, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-03-24
公開日2006-09-24
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the PH domain of TBC1 domain family member 2 protein from human
To be Published
2D9V
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BU of 2d9v by Molmil
Solution structure of the PH domain of Pleckstrin homology domain-containing protein family B member 1 from mouse
分子名称: Pleckstrin homology domain-containing protein family B member 1
著者Li, H, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-13
公開日2006-06-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the PH domain of Pleckstrin homology domain-containing protein family B member 1 from mouse
To be Published
2D9Z
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BU of 2d9z by Molmil
Solution structure of the PH domain of Protein kinase C, nu type from human
分子名称: Protein kinase C, nu type
著者Li, H, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-13
公開日2007-01-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the PH domain of Protein kinase C, nu type from human
To be Published
2D9X
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BU of 2d9x by Molmil
Solution structure of the PH domain of Oxysterol binding protein-related protein 11 from human
分子名称: Oxysterol binding protein-related protein 11
著者Li, H, Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-13
公開日2006-06-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the PH domain of Oxysterol binding protein-related protein 11 from human
To be Published
2D9W
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BU of 2d9w by Molmil
Solution structure of the PH domain of Docking protein 2 from human
分子名称: Docking protein 2
著者Li, H, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-13
公開日2006-06-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the PH domain of Docking protein 2 from human
To be Published
2DA0
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BU of 2da0 by Molmil
Solution structure of the PH domain of PIP2-dependent ARF1 GTPase-activating protein from human
分子名称: 130-kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein
著者Li, H, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-13
公開日2006-06-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the PH domain of PIP2-dependent ARF1 GTPase-activating protein from human
To be Published
2D9Y
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BU of 2d9y by Molmil
Solution structure of the PH domain of PEPP-3 from human
分子名称: Pleckstrin homology domain-containing protein family A member 6
著者Li, H, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-13
公開日2006-06-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the PH domain of PEPP-3 from human
To be Published
2D9T
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BU of 2d9t by Molmil
Solution structure of the Tudor domain of Tudor domain containing protein 3 from mouse
分子名称: Tudor domain-containing protein 3
著者Li, H, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-13
公開日2006-06-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the Tudor domain of Tudor domain containing protein 3 from mouse
To be Published
7UAN
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BU of 7uan by Molmil
Structure of rat neuronal nitric oxide synthase R349A heme domain in complex with (6-(3-(4,4-difluoropiperidin-1-yl)propyl)-4-methylpyridin-2-amine)
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 6-[3-(4,4-difluoropiperidin-1-yl)propyl]-4-methylpyridin-2-amine, ACETATE ION, ...
著者Li, H, Poulos, T.L.
登録日2022-03-13
公開日2022-07-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.6969 Å)
主引用文献2-Aminopyridines with a shortened amino sidechain as potent, selective, and highly permeable human neuronal nitric oxide synthase inhibitors.
Bioorg.Med.Chem., 69, 2022
3S8M
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BU of 3s8m by Molmil
The Crystal Structure of FabV
分子名称: Enoyl-ACP Reductase
著者Li, H, Zhang, X.L, Bi, L.J, He, J, Jiang, T.
登録日2011-05-29
公開日2011-11-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Determination of the Crystal Structure and Active Residues of FabV, the Enoyl-ACP Reductase from Xanthomonas oryzae.
Plos One, 6, 2011
7TSE
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BU of 7tse by Molmil
Structure of rat neuronal nitric oxide synthase R349A mutant heme domain in complex with 6-(3-(3,3-difluoroazetidin-1-yl)propyl)-4-methylpyridin-2-amine
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 6-[3-(3,3-difluoroazetidin-1-yl)propyl]-4-methylpyridin-2-amine, ACETATE ION, ...
著者Li, H, Poulos, T.L.
登録日2022-01-31
公開日2022-07-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献2-Aminopyridines with a shortened amino sidechain as potent, selective, and highly permeable human neuronal nitric oxide synthase inhibitors.
Bioorg.Med.Chem., 69, 2022
7TSA
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BU of 7tsa by Molmil
Structure of rat neuronal nitric oxide synthase R349A/H692F mutant heme domain in complex with 4-methyl-6-(3-((methylamino)methyl)phenyl)pyridin-2-amine
分子名称: 4-methyl-6-{3-[(methylamino)methyl]phenyl}pyridin-2-amine, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ...
著者Li, H, Poulos, T.L.
登録日2022-01-31
公開日2022-07-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献2-Aminopyridines with a shortened amino sidechain as potent, selective, and highly permeable human neuronal nitric oxide synthase inhibitors.
Bioorg.Med.Chem., 69, 2022
7TSC
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BU of 7tsc by Molmil
Structure of rat neuronal nitric oxide synthase R349A mutant heme domain in complex with 4-methyl-6-(3-(4-methylpiperazin-1-yl)propyl)pyridin-2-amine
分子名称: 4-methyl-6-[3-(4-methylpiperazin-1-yl)propyl]pyridin-2-amine, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ...
著者Li, H, Poulos, T.L.
登録日2022-01-31
公開日2022-07-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.7959 Å)
主引用文献2-Aminopyridines with a shortened amino sidechain as potent, selective, and highly permeable human neuronal nitric oxide synthase inhibitors.
Bioorg.Med.Chem., 69, 2022
7TSD
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BU of 7tsd by Molmil
Structure of rat neuronal nitric oxide synthase R349A mutant heme domain in complex with 6-(3-(3,3-difluoroazetidin-1-yl)prop-1-yn-1-yl)-4-methylpyridin-2-amine
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 6-[3-(3,3-difluoroazetidin-1-yl)prop-1-yn-1-yl]-4-methylpyridin-2-amine, ACETATE ION, ...
著者Li, H, Poulos, T.L.
登録日2022-01-31
公開日2022-07-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.769 Å)
主引用文献2-Aminopyridines with a shortened amino sidechain as potent, selective, and highly permeable human neuronal nitric oxide synthase inhibitors.
Bioorg.Med.Chem., 69, 2022
7TS9
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Structure of rat neuronal nitric oxide synthase R349A heme domain in complex with 6-(3-(dimethylamino)propyl)-4-methylpyridin-2-amine
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 6-[3-(dimethylamino)propyl]-4-methylpyridin-2-amine, ACETATE ION, ...
著者Li, H, Poulos, T.L.
登録日2022-01-31
公開日2022-07-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8526 Å)
主引用文献2-Aminopyridines with a shortened amino sidechain as potent, selective, and highly permeable human neuronal nitric oxide synthase inhibitors.
Bioorg.Med.Chem., 69, 2022
7TSB
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BU of 7tsb by Molmil
Structure of rat neuronal nitric oxide synthase R349A heme domain in complex with 4-methyl-6-(3-(methylamino)prop-1-yn-1-yl)pyridin-2-amine
分子名称: 4-methyl-6-[3-(methylamino)prop-1-yn-1-yl]pyridin-2-amine, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ...
著者Li, H, Poulos, T.L.
登録日2022-01-31
公開日2022-07-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8177 Å)
主引用文献2-Aminopyridines with a shortened amino sidechain as potent, selective, and highly permeable human neuronal nitric oxide synthase inhibitors.
Bioorg.Med.Chem., 69, 2022
6LN1
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A natural inhibitor of DYRK1A for treatment of diabetes mellitus
分子名称: 1,3,5,8-tetrakis(oxidanyl)xanthen-9-one, Dual specificity tyrosine-phosphorylation-regulated kinase 1A
著者Li, H, Chen, L.X, Zheng, M.Z, Zhang, Q.Z, Zhang, C.L, Wu, C.R, Yang, K.Y, Song, Z.R, Wang, Q.Q, Li, C, Zhou, Y.R, Chen, J.C.
登録日2019-12-28
公開日2021-10-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.699 Å)
主引用文献A natural DYRK1A inhibitor as a potential stimulator for beta-cell proliferation in diabetes.
Clin Transl Med, 11, 2021

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