7SHV
 
 | | Crystal structure of BRAF kinase domain bound to GDC0879 | | Descriptor: | 2-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-inden-5-yl]-3-(pyridin-4-yl)-1H-pyrazol-1-yl}ethanol, CHLORIDE ION, Serine/threonine-protein kinase B-raf | | Authors: | Kung, J.E, Sudhamsu, J. | | Deposit date: | 2021-10-11 | | Release date: | 2022-10-26 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.88 Å) | | Cite: | Clearing the Path to Rapid High-Quality Protein Purification
To Be Published
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7SI1
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8VGE
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8VGP
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8VGL
 | | CryoEM structure of Nav1.7 in complex with wild type Fab 7A9 | | Descriptor: | Chimeric Nav1.7-NavAb, Fab 7A9 heavy chain, Fab 7A9 light chain | | Authors: | Kung, J.E, Jao, C.C, Arthur, C.P, Sudhamsu, J. | | Deposit date: | 2023-12-27 | | Release date: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Disulfi de constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM.
Biorxiv, 2024
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8VEG
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8VGF
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8VGJ
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8VGM
 | | CryoEM structure of Nav1.7 in complex with engineered conformationally rigid Fab 7A9.4DS | | Descriptor: | Chimeric Nav1.7-NavAb, Fab 7A9.4DS heavy chain, Fab 7A9.4DS light chain | | Authors: | Kung, J.E, Jao, C.C, Arthur, C.P, Sudhamsu, J. | | Deposit date: | 2023-12-27 | | Release date: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Disulfi de constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM.
Biorxiv, 2024
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8VGG
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8VGK
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8VGQ
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8VGH
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8VGI
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8VGO
 | | CryoEM structure of CD20 in complex with engineered conformationally rigid Rituximab.4DS Fab | | Descriptor: | B-lymphocyte antigen CD20, Rituximab.4DS Fab heavy chain, Rituximab.4DS Fab light chain | | Authors: | Kung, J.E, Jao, C.C, Arthur, C.P, Sudhamsu, J. | | Deposit date: | 2023-12-27 | | Release date: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Disulfide constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM.
Biorxiv, 2024
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8VGN
 | | CryoEM structure of CD20 in complex with wild type Rituximab Fab | | Descriptor: | B-lymphocyte antigen CD20, Rituximab Fab heavy chain, Rituximab Fab light chain | | Authors: | Kung, J.E, Jao, C.C, Arthur, C.P, Sudhamsu, J. | | Deposit date: | 2023-12-27 | | Release date: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Disulfide constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM.
Biorxiv, 2024
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