9BD2
 
 | | MAGE-A3 MHD crystal soaked with KL861 | | Descriptor: | (furan-2-yl)[4-({(5P)-5-(1H-indazol-4-yl)-2-[3-(morpholin-4-yl)propoxy]phenyl}methyl)piperazin-1-yl]methanone, Melanoma-associated antigen 3 | | Authors: | Butrin, A, Krone, M.W, Li, K, Bond, M.J, Linhares, B.M, Crews, C. | | Deposit date: | 2024-04-10 | | Release date: | 2024-09-18 | | Last modified: | 2024-09-25 | | Method: | X-RAY DIFFRACTION (2.24 Å) | | Cite: | Development of Ligands and Degraders Targeting MAGE-A3.
J.Am.Chem.Soc., 146, 2024
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6MHA
 | | dHP1 Chromodomain Y24W variant bound to histone H3 peptide containing trimethyllysine | | Descriptor: | Heterochromatin protein 1, histone H3 peptide containing trimethyllysine, H3K9me3 | | Authors: | Brustad, E.M, Krone, M.W, Albanese, K.I, Waters, M.L. | | Deposit date: | 2018-09-17 | | Release date: | 2019-09-25 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.497 Å) | | Cite: | Thermodynamic consequences of Tyr to Trp mutations in the cation-pi-mediated binding of trimethyllysine by the HP1 chromodomain
Chem Sci, 11, 2020
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