9BD2

MAGE-A3 MHD crystal soaked with KL861

This is a non-PDB format compatible entry.

Summary for 9BD2

• Entry DOI: 10.2210/pdb9bd2/pdb
• Descriptor: Melanoma-associated antigen 3, (furan-2-yl)[4-({(5P)-5-(1H-indazol-4-yl)-2-[3-(morpholin-4-yl)propoxy]phenyl}methyl)piperazin-1-yl]methanone (3 entities in total)
• Functional Keywords: mage-a3, melanoma-associated antigen 3, mage, mage-a3 mhd, kl861, oncoprotein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 71555.96

Authors

Butrin, A.,Krone, M.W.,Li, K.,Bond, M.J.,Linhares, B.M.,Crews, C. (deposition date: 2024-04-10, release date: 2024-09-18, Last modification date: 2024-09-25)

• Primary citation: Li, K.,Krone, M.W.,Butrin, A.,Bond, M.J.,Linhares, B.M.,Crews, C.M.; Development of Ligands and Degraders Targeting MAGE-A3.; J.Am.Chem.Soc., 146:24884-24891, 2024; PubMed: 39190582; DOI: 10.1021/jacs.4c05393

Experimental method

X-RAY DIFFRACTION (2.24 Å)