3WOE
 
 | | Crystal structure of P23-45 gp39 (6-109) bound to Thermus thermophilus RNA polymerase beta-flap domain | | 分子名称: | DNA-directed RNA polymerase subunit beta, Putative uncharacterized protein | | 著者 | Tagami, S, Sekine, S, Minakhin, L, Esyunina, D, Akasaka, R, Shirouzu, M, Kulbachinskiy, A, Severinov, K, Yokoyama, S. | | 登録日 | 2013-12-26 | | 公開日 | 2014-03-12 | | 最終更新日 | 2015-03-25 | | 実験手法 | X-RAY DIFFRACTION (2.351 Å) | | 主引用文献 | Structural basis for promoter specificity switching of RNA polymerase by a phage factor.
Genes Dev., 28, 2014
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8IFJ
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2SXL
 | | SEX-LETHAL RBD1, NMR, MINIMIZED AVERAGE STRUCTURE | | 分子名称: | SEX-LETHAL PROTEIN | | 著者 | Inoue, M, Muto, Y, Sakamoto, H, Kigawa, T, Takio, K, Shimura, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 1997-07-16 | | 公開日 | 1998-07-22 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A characteristic arrangement of aromatic amino acid residues in the solution structure of the amino-terminal RNA-binding domain of Drosophila sex-lethal.
J.Mol.Biol., 272, 1997
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3WEX
 | | Crystal structure of HLA-DP5 in complex with Cry j 1-derived peptide (residues 214-222) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II antigen | | 著者 | Kusano, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S. | | 登録日 | 2013-07-16 | | 公開日 | 2014-07-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for the specific recognition of the major antigenic peptide from the Japanese cedar pollen allergen Cry j 1 by HLA-DP5
J. Mol. Biol., 426, 2014
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3CPQ
 | | Crystal Structure of L30e a ribosomal protein from Methanocaldococcus jannaschii DSM2661 (MJ1044) | | 分子名称: | 50S ribosomal protein L30e | | 著者 | Jeyakanthan, J, Sarani, R, Mridula, P, Sekar, K, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2008-04-01 | | 公開日 | 2009-04-07 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal Structure of L30e a ribosomal protein from Methanocaldococcus jannaschii DSM2661 (MJ1044)
To be Published
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6KGL
 | | LSD1-CoREST-S2101 N5 adduct model | | 分子名称: | 3-[3,5-bis(fluoranyl)-2-phenylmethoxy-phenyl]propanal, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | 著者 | Niwa, H, Sato, S, Sengoku, S, Umehara, T, Yokoyama, S. | | 登録日 | 2019-07-12 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Development and Structural Evaluation of N-Alkylated trans-2-Phenylcyclopropylamine-Based LSD1 Inhibitors.
Chemmedchem, 15, 2020
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4YZO
 | | Crystal Structure Analysis of Thiolase-like protein, ST0096 from Sulfolobus Tokodaii | | 分子名称: | ACETATE ION, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Padmanabhan, B, Manjula, R, Yokoyama, S, Bessho, Y. | | 登録日 | 2015-03-25 | | 公開日 | 2016-03-30 | | 最終更新日 | 2020-02-19 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structure Analysis of Thiolase-like protein, ST0096 from Sulfolobus Tokodaii
To Be Published
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3NJP
 | | The Extracellular and Transmembrane Domain Interfaces in Epidermal Growth Factor Receptor Signaling | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor, Epidermal growth factor receptor, ... | | 著者 | Lu, C, Mi, L.-Z, Grey, M.J, Zhu, J, Graef, E, Yokoyama, S, Springer, T.A. | | 登録日 | 2010-06-17 | | 公開日 | 2010-10-13 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.304 Å) | | 主引用文献 | Structural evidence for loose linkage between ligand binding and kinase activation in the epidermal growth factor receptor.
Mol.Cell.Biol., 30, 2010
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3VS2
 | | Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 7-[cis-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine | | 分子名称: | 7-[cis-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Kuratani, M, Tomabechi, Y, Niwa, H, Parker, J.L, Handa, N, Yokoyama, S. | | 登録日 | 2012-04-21 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.609 Å) | | 主引用文献 | A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo
Sci Transl Med, 5, 2013
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6KGK
 | | LSD1-CoREST-S2101 five-membered ring adduct model | | 分子名称: | 3-[3,5-bis(fluoranyl)-2-phenylmethoxy-phenyl]propanal, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | 著者 | Niwa, H, Sato, S, Sengoku, S, Umehara, T, Yokoyama, S. | | 登録日 | 2019-07-12 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Development and Structural Evaluation of N-Alkylated trans-2-Phenylcyclopropylamine-Based LSD1 Inhibitors.
Chemmedchem, 15, 2020
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3VRZ
 | | Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 1-[4-(4-amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-3-benzylurea | | 分子名称: | 1-[4-(4-amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-3-benzylurea, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Kuratani, M, Tomabechi, Y, Handa, N, Yokoyama, S. | | 登録日 | 2012-04-21 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.218 Å) | | 主引用文献 | A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo
Sci Transl Med, 5, 2013
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3VRY
 | | Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 4-Amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl-cyclopentane | | 分子名称: | 4-Amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl-cyclopentane, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Kuratani, M, Tomabechi, Y, Niwa, H, Handa, N, Yokoyama, S. | | 登録日 | 2012-04-21 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.481 Å) | | 主引用文献 | A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo
Sci Transl Med, 5, 2013
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3BOY
 | | Crystal structure of the HutP antitermination complex bound to the HUT mRNA | | 分子名称: | 5'-R(*UP*UP*UP*AP*GP*UP*UP*UP*UP*UP*AP*GP*UP*UP*UP*UP*UP*AP*GP*UP*UP*U)-3', HISTIDINE, Hut operon positive regulatory protein, ... | | 著者 | Kumarevel, T.S, Balasundaresan, D, Jeyakanthan, J, Shinkai, A, Yokoyama, S, Kumar, P.K.R, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-12-18 | | 公開日 | 2008-01-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structure of HutP complexed with the 55-mer RNA
To be Published
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3VS7
 | | Crystal structure of HCK complexed with a pyrazolo-pyrimidine inhibitor 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | | 分子名称: | 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Kuratani, M, Honda, K, Niwa, H, Toyama, M, Handa, N, Yokoyama, S. | | 登録日 | 2012-04-21 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (3.001 Å) | | 主引用文献 | A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo
Sci Transl Med, 5, 2013
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3W1I
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3W1K
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3SUS
 | | Crystal structure of beta-hexosaminidase from Paenibacillus sp. TS12 in complex with Gal-NAG-thiazoline | | 分子名称: | (3aR,5R,6R,7R,7aR)-5-(hydroxymethyl)-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol, Beta-hexosaminidase, SULFATE ION | | 著者 | Sumida, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2011-07-11 | | 公開日 | 2012-06-06 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Gaining insight into the inhibition of glycoside hydrolase family 20 exo-beta-N-acetylhexosaminidases using a structural approach
Org.Biomol.Chem., 10, 2012
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1FL0
 | | CRYSTAL STRUCTURE OF THE EMAP2/RNA-BINDING DOMAIN OF THE P43 PROTEIN FROM HUMAN AMINOACYL-TRNA SYNTHETASE COMPLEX | | 分子名称: | ENDOTHELIAL-MONOCYTE ACTIVATING POLYPEPTIDE II | | 著者 | Renault, L, Kerjan, P, Pasqualato, S, Menetrey, J, Robinson, J.-C, Kawaguchi, S, Vassylyev, D.G, Yokoyama, S, Mirande, M, Cherfils, J. | | 登録日 | 2000-08-11 | | 公開日 | 2000-12-06 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of the EMAPII domain of human aminoacyl-tRNA synthetase complex reveals evolutionary dimer mimicry.
EMBO J., 20, 2001
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6AAC
 | | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with mAzZLys | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | | 著者 | Yanagisawa, T, Kuratani, M, Yokoyama, S. | | 登録日 | 2018-07-18 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.479 Å) | | 主引用文献 | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
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6AB1
 | | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with oAzZLys | | 分子名称: | (2S)-2-azanyl-6-[(2-azidophenyl)methoxycarbonylamino]hexanoic acid, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Yanagisawa, T, Kuratani, M, Yokoyama, S. | | 登録日 | 2018-07-19 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.381 Å) | | 主引用文献 | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
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6ABL
 | | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with oBrZLys | | 分子名称: | (2S)-2-azanyl-6-[(2-bromophenyl)methoxycarbonylamino]hexanoic acid, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Yanagisawa, T, Kuratani, M, Yokoyama, S. | | 登録日 | 2018-07-22 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
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6ABM
 | | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with pTmdZLys | | 分子名称: | (2S)-2-azanyl-6-[[4-[3-(trifluoromethyl)-1,2-diazirin-3-yl]phenyl]methoxycarbonylamino]hexanoic acid, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Yanagisawa, T, Kuratani, M, Yokoyama, S. | | 登録日 | 2018-07-22 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.368 Å) | | 主引用文献 | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
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5AV5
 | | human nucleosome core particle | | 分子名称: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Wakamori, M, Fujii, Y, Umehara, T, Yokoyama, S. | | 登録日 | 2015-06-11 | | 公開日 | 2015-12-23 | | 最終更新日 | 2020-02-19 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation
Sci Rep, 5, 2015
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6AAZ
 | | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with pNO2ZLys | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CITRIC ACID, MAGNESIUM ION, ... | | 著者 | Yanagisawa, T, Kuratani, M, Yokoyama, S. | | 登録日 | 2018-07-19 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.842 Å) | | 主引用文献 | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
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6AB8
 | | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with ZLys | | 分子名称: | (2S)-2-azanyl-6-(phenylmethoxycarbonylamino)hexanoic acid, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Yanagisawa, T, Kuratani, M, Yokoyama, S. | | 登録日 | 2018-07-20 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.753 Å) | | 主引用文献 | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
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