5N6I
 
 | | Crystal structure of mouse cGAS in complex with 39 bp DNA | | 分子名称: | Cyclic GMP-AMP synthase, DNA (36-MER), DNA (37-MER), ... | | 著者 | Andreeva, L, Kostrewa, D, Hopfner, K.-P. | | 登録日 | 2017-02-15 | | 公開日 | 2017-09-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders.
Nature, 549, 2017
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5HCI
 | | GPN-loop GTPase Npa3 in complex with GDP | | 分子名称: | GLYCEROL, GPN-loop GTPase 1, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Niesser, J, Wagner, F.R, Kostrewa, D, Muehlbacher, W, Cramer, P. | | 登録日 | 2016-01-04 | | 公開日 | 2016-01-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of GPN-Loop GTPase Npa3 and Implications for RNA Polymerase II Assembly.
Mol.Cell.Biol., 36, 2015
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5HCN
 | | GPN-loop GTPase Npa3 in complex with GMPPCP | | 分子名称: | GLYCEROL, GPN-loop GTPase 1, LAURIC ACID, ... | | 著者 | Niesser, J, Wagner, F.R, Kostrewa, D, Muehlbacher, W, Cramer, P. | | 登録日 | 2016-01-04 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of GPN-Loop GTPase Npa3 and Implications for RNA Polymerase II Assembly.
Mol.Cell.Biol., 36, 2015
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4C2M
 | | Structure of RNA polymerase I at 2.8 A resolution | | 分子名称: | DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA14, ... | | 著者 | Engel, C, Sainsbury, S, Cheung, A.C, Kostrewa, D, Cramer, P. | | 登録日 | 2013-08-19 | | 公開日 | 2013-10-23 | | 最終更新日 | 2015-08-19 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | RNA Polymerase I Structure and Transcription Regulation.
Nature, 502, 2013
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3OTX
 | | Crystal Structure of Trypanosoma brucei rhodesiense Adenosine Kinase Complexed with Inhibitor AP5A | | 分子名称: | Adenosine kinase, putative, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, ... | | 著者 | Kuettel, S, Greenwald, J, Kostrewa, D, Ahmed, S, Scapozza, L, Perozzo, R. | | 登録日 | 2010-09-14 | | 公開日 | 2011-06-29 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal Structures of T. b. rhodesiense Adenosine Kinase Complexed with Inhibitor and Activator: Implications for Catalysis and Hyperactivation
Plos Negl Trop Dis, 5, 2011
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3QT1
 | | RNA polymerase II variant containing A Chimeric RPB9-C11 subunit | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | 著者 | Ruan, W, Lehmann, E, Thomm, M, Kostrewa, D, Cramer, P. | | 登録日 | 2011-02-22 | | 公開日 | 2011-03-23 | | 最終更新日 | 2017-08-23 | | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | | 主引用文献 | Evolution of two modes of intrinsic RNA polymerase transcript cleavage.
J.Biol.Chem., 286, 2011
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3N8B
 | | Crystal Structure of Borrelia burgdorferi Pur-alpha | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, Uncharacterized protein | | 著者 | Graebsch, A, Roche, S, Kostrewa, D, Niessing, D. | | 登録日 | 2010-05-28 | | 公開日 | 2010-10-06 | | 最終更新日 | 2018-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Of bits and bugs--on the use of bioinformatics and a bacterial crystal structure to solve a eukaryotic repeat-protein structure.
Plos One, 5, 2010
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3NM7
 | | Crystal Structure of Borrelia burgdorferi Pur-alpha | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, Uncharacterized protein | | 著者 | Graebsch, A, Roche, S, Kostrewa, D, Niessing, D. | | 登録日 | 2010-06-22 | | 公開日 | 2010-10-06 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Of Bits and Bugs - on the use of bioinformatics and a bacterial crystal structure to solve a eukaryotic repeat-protein structure.
Plos One, 5, 2010
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6SKY
 | | FAT and kinase domain of CtTel1 | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase Tel1 | | 著者 | Jansma, M, Eustermann, S.E, Kostrewa, D, Lammens, K, Hopfner, K.P. | | 登録日 | 2019-08-16 | | 公開日 | 2019-10-30 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State.
Structure, 28, 2020
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6SL0
 | | Complete CtTel1 dimer with C2 symmetry | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase Tel1 | | 著者 | Jansma, M, Eustermann, S.E, Kostrewa, D, Lammens, K, Hopfner, K.P. | | 登録日 | 2019-08-16 | | 公開日 | 2019-10-30 | | 最終更新日 | 2020-01-15 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State.
Structure, 28, 2020
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1S9Z
 | | SYNTHETIC 17 AMINO ACID LONG PEPTIDE THAT FORMS A NATIVE-LIKE COILED-COIL AT AMBIENT TEMPERATURE AND AGGREGATES INTO AMYLOID-LIKE FIBRILS AT HIGHER TEMPERATURES. | | 分子名称: | SODIUM ION, SYNTHETIC COILED-COIL PEPTIDE, ZINC ION | | 著者 | Kammerer, R.A, Kostrewa, D, Zurdo, J, Detken, A, Garcia-Echeverria, C, Green, J.D, Muller, S.A, Meier, B.H, Winkler, F.K, Dobson, C.M, Steinmetz, M.O. | | 登録日 | 2004-02-06 | | 公開日 | 2004-04-06 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Exploring amyloid formation by a de novo design
Proc.Natl.Acad.Sci.USA, 101, 2004
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6SL1
 | | Structure of the open conformation of CtTel1 | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase Tel1 | | 著者 | Jansma, M, Eustermann, S.E, Kostrewa, D, Lammens, K, Hopfner, K.P. | | 登録日 | 2019-08-16 | | 公開日 | 2019-10-30 | | 最終更新日 | 2020-05-13 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State.
Structure, 28, 2020
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6SKZ
 | | Structure of the closed conformation of CtTel1 | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase Tel1 | | 著者 | Jansma, M, Eustermann, S.E, Kostrewa, D, Lammens, K, Hopfner, K.P. | | 登録日 | 2019-08-16 | | 公開日 | 2019-10-30 | | 最終更新日 | 2020-01-15 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State.
Structure, 28, 2020
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3NFF
 | | Crystal structure of extended Dimerization module of RNA polymerase I subcomplex A49/A34.5 | | 分子名称: | RNA polymerase I subunit A34.5, RNA polymerase I subunit A49 | | 著者 | Geiger, S.R, Lorenzen, K, Schreieck, A, Hanecker, P, Kostrewa, D, Heck, A.J.R, Cramer, P. | | 登録日 | 2010-06-10 | | 公開日 | 2010-09-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.24 Å) | | 主引用文献 | RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex.
Mol.Cell, 39, 2010
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3NFH
 | | Crystal structure of tandem winged helix domain of RNA polymerase I subunit A49 (P4) | | 分子名称: | DNA-directed RNA polymerase I subunit RPA49 | | 著者 | Geiger, S.R, Lorenzen, K, Schreieck, A, Hanecker, P, Kostrewa, D, Heck, A.J.R, Cramer, P. | | 登録日 | 2010-06-10 | | 公開日 | 2010-09-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex.
Mol.Cell, 39, 2010
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3NFI
 | | Crystal structure of tandem winged helix domain of RNA polymerase I subunit A49 | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DNA-directed RNA polymerase I subunit RPA49 | | 著者 | Geiger, S.R, Lorenzen, K, Schreieck, A, Hanecker, P, Kostrewa, D, Heck, A.J.R, Cramer, P. | | 登録日 | 2010-06-10 | | 公開日 | 2010-09-08 | | 最終更新日 | 2015-03-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex.
Mol.Cell, 39, 2010
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1WU9
 | | Crystal structure of the C-terminal domain of the end-binding protein 1 (EB1) | | 分子名称: | Microtubule-associated protein RP/EB family member 1 | | 著者 | Honnappa, S, John, C.M, Kostrewa, D, Winkler, F.K, Steinmetz, M.O. | | 登録日 | 2004-12-02 | | 公開日 | 2005-02-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Structural insights into the EB1-APC interaction
Embo J., 24, 2005
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8A5Q
 | | Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of Chaetomium thermophilum INO80 on straight DNA | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin related protein 4 (Arp4), ... | | 著者 | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | | 登録日 | 2022-06-15 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
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8A5P
 | | Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of Chaetomium thermophilum INO80 on curved DNA | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin related protein 4 (Arp4), ... | | 著者 | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | | 登録日 | 2022-06-15 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
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8A5A
 | | Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of INO80 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-like protein ARP8, ... | | 著者 | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | | 登録日 | 2022-06-14 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
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8A5O
 | | Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of S. cerevisiae INO80 | | 分子名称: | Actin, Actin-like protein ARP8, Actin-related protein 4, ... | | 著者 | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | | 登録日 | 2022-06-15 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
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8A5D
 | | Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of Chaetomium thermophilum INO80 | | 分子名称: | Actin, Actin related protein 4 (Arp4), Actin-related protein 8, ... | | 著者 | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | | 登録日 | 2022-06-14 | | 公開日 | 2022-12-28 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
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8ATF
 | | Nucleosome-bound Ino80 ATPase | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (226-MER), DNA (227-MER), ... | | 著者 | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | | 登録日 | 2022-08-23 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
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8AV6
 | | CryoEM structure of INO80 core nucleosome complex in closed grappler conformation | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DASH complex subunit DAD4, ... | | 著者 | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | | 登録日 | 2022-08-26 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (4.68 Å) | | 主引用文献 | Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
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1YNQ
 | | aldo-keto reductase AKR11C1 from Bacillus halodurans (holo form) | | 分子名称: | GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SODIUM ION, ... | | 著者 | Marquardt, T, Kostrewa, D, Winkler, F.K, Li, X.D. | | 登録日 | 2005-01-25 | | 公開日 | 2005-12-06 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | High-resolution Crystal Structure of AKR11C1 from Bacillus halodurans: An NADPH-dependent 4-Hydroxy-2,3-trans-nonenal Reductase
J.Mol.Biol., 354, 2005
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