1D9W
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1XK4
| Crystal structure of human calprotectin(S100A8/S100A9) | 分子名称: | CALCIUM ION, CHLORIDE ION, CITRATE ANION, ... | 著者 | Korndoerfer, I.P, Brueckner, F, Skerra, A. | 登録日 | 2004-09-26 | 公開日 | 2005-10-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The crystal structure of the human (S100A8/S100A9)2 heterotetramer, calprotectin, illustrates how conformational changes of interacting alpha-helices can determine specific association of two EF-hand proteins J.Mol.Biol., 370, 2007
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1XOV
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1KXO
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1LNM
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1LKE
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3INW
| HSP90 N-TERMINAL DOMAIN with pochoxime A | 分子名称: | (5E,9E,11E)-13-chloro-14,16-dihydroxy-3,4,7,8-tetrahydro-1H-2-benzoxacyclotetradecine-1,11(12H)-dione 11-[O-(2-oxo-2-piperidin-1-ylethyl)oxime], DIMETHYL SULFOXIDE, Heat shock protein HSP 90-alpha | 著者 | Korndoerfer, I.P. | 登録日 | 2009-08-13 | 公開日 | 2010-08-18 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Inhibition of HSP90 with pochoximes: SAR and structure-based insights. Chembiochem, 10, 2009
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3INX
| HSP90 N-TERMINAL DOMAIN with pochoxime B | 分子名称: | (5E,9E,11E)-14,16-dihydroxy-3,4,7,8-tetrahydro-1H-2-benzoxacyclotetradecine-1,11(12H)-dione 11-[O-(2-oxo-2-piperidin-1-ylethyl)oxime], DIMETHYL SULFOXIDE, Heat shock protein HSP 90-alpha | 著者 | Korndoerfer, I.P. | 登録日 | 2009-08-13 | 公開日 | 2010-08-18 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Inhibition of HSP90 with pochoximes: SAR and structure-based insights. Chembiochem, 10, 2009
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1KL4
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1KL3
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1KFF
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1KL5
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1N0S
| ENGINEERED LIPOCALIN FLUA IN COMPLEX WITH FLUORESCEIN | 分子名称: | 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, Bilin-binding protein, SULFATE ION | 著者 | Korndoerfer, I.P, Skerra, A. | 登録日 | 2002-10-15 | 公開日 | 2003-08-05 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystallographic analysis of an "anticalin" with tailored specificity for fluorescein reveals high structural plasticity of the lipocalin loop region. Proteins, 53, 2003
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1XKI
| Crystal structure of human tear lipocalin/von Ebners gland protein | 分子名称: | CHLORIDE ION, Von Ebner's gland protein, ZINC ION | 著者 | Breustedt, D.A, Korndoerfer, I.P, Redl, B, Skerra, A. | 登録日 | 2004-09-29 | 公開日 | 2004-10-19 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The 1.8-A crystal structure of human tear lipocalin reveals an extended branched cavity with capacity for multiple ligands J.Biol.Chem., 280, 2005
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5LGE
| Crystal Structure of human IDH1 mutant (R132H) in complex with NADP+ and an Inhibitor related to BAY 1436032 | 分子名称: | 1,2-ETHANEDIOL, 2-[(4-propan-2-ylphenyl)amino]-1-[(1~{S},5~{S})-3,3,5-trimethylcyclohexyl]benzimidazole-5-carboxylic acid, ACETATE ION, ... | 著者 | Hillig, R.C, Hars, U, Korndoerfer, I.P. | 登録日 | 2016-07-07 | 公開日 | 2017-02-08 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo. Acta Neuropathol., 133, 2017
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