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PDB: 56 件

1QFU
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BU of 1qfu by Molmil
INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (HEMAGGLUTININ (HA1 CHAIN)), ...
著者Fleury, D, Gigant, B, Bizebard, T, Daniels, R.S, Skehel, J.J, Knossow, M.
登録日1999-04-14
公開日1999-04-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A complex of influenza hemagglutinin with a neutralizing antibody that binds outside the virus receptor binding site.
Nat.Struct.Biol., 6, 1999
4Y05
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KIF2C short Loop2 construct
分子名称: ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF2C, MAGNESIUM ION, ...
著者Wang, W, Knossow, M, Gigant, B.
登録日2015-02-05
公開日2015-06-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献New Insights into the Coupling between Microtubule Depolymerization and ATP Hydrolysis by Kinesin-13 Protein Kif2C.
J.Biol.Chem., 290, 2015
5EYP
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TUBULIN-DARPIN COMPLEX
分子名称: DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN), GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ...
著者Ahmad, S, Knossow, M, Gigant, B.
登録日2015-11-25
公開日2016-07-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Destabilizing an interacting motif strengthens the association of a designed ankyrin repeat protein with tubulin.
Sci Rep, 6, 2016
2VIU
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BU of 2viu by Molmil
INFLUENZA VIRUS HEMAGGLUTININ
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Bizebard, T, Fleury, D, Gigant, B, Wharton, S.A, Skehel, J.J, Knossow, M.
登録日1997-12-22
公開日1998-04-29
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Antigen distortion allows influenza virus to escape neutralization.
Nat.Struct.Biol., 5, 1998
2VIR
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BU of 2vir by Molmil
INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY
分子名称: HEMAGGLUTININ, IMMUNOGLOBULIN (IGG1, LAMBDA), ...
著者Bizebard, T, Fleury, D, Gigant, B, Wharton, S.A, Skehel, J.J, Knossow, M.
登録日1997-12-22
公開日1998-04-29
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Antigen distortion allows influenza virus to escape neutralization.
Nat.Struct.Biol., 5, 1998
2VIS
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BU of 2vis by Molmil
INFLUENZA VIRUS HEMAGGLUTININ, (ESCAPE) MUTANT WITH THR 131 REPLACED BY ILE, COMPLEXED WITH A NEUTRALIZING ANTIBODY
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, IMMUNOGLOBULIN (IGG1, ...
著者Bizebard, T, Fleury, D, Gigant, B, Wharton, S.A, Skehel, J.J, Knossow, M.
登録日1997-12-22
公開日1998-04-29
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Antigen distortion allows influenza virus to escape neutralization.
Nat.Struct.Biol., 5, 1998
4LNU
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Nucleotide-free kinesin motor domain in complex with tubulin and a DARPin
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Designed ankyrin repeat protein (DARPIN) D1, GLYCEROL, ...
著者Cao, L, Gigant, B, Knossow, M.
登録日2013-07-12
公開日2014-12-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献The structure of apo-kinesin bound to tubulin links the nucleotide cycle to movement
Nat Commun, 5, 2014
2VIT
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BU of 2vit by Molmil
INFLUENZA VIRUS HEMAGGLUTININ, MUTANT WITH THR 155 REPLACED BY ILE, COMPLEXED WITH A NEUTRALIZING ANTIBODY
分子名称: HEMAGGLUTININ, IMMUNOGLOBULIN (IGG1, LAMBDA), ...
著者Bizebard, T, Fleury, D, Gigant, B, Wharton, S.A, Skehel, J.J, Knossow, M.
登録日1997-12-22
公開日1998-04-29
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Antigen distortion allows influenza virus to escape neutralization.
Nat.Struct.Biol., 5, 1998
4DRX
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BU of 4drx by Molmil
GTP-Tubulin in complex with a DARPIN
分子名称: Designed ankyrin repeat protein (DARPIN) D1, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Pecqueur, L, Gigant, B, Knossow, M.
登録日2012-02-17
公開日2012-07-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end.
Proc.Natl.Acad.Sci.USA, 109, 2012
3E22
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BU of 3e22 by Molmil
Tubulin-colchicine-soblidotin: Stathmin-like domain complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Cormier, A, Marchand, M, Ravelli, R.B, Knossow, M, Gigant, B.
登録日2008-08-05
公開日2008-10-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural insight into the inhibition of tubulin by vinca domain peptide ligands
Embo Rep., 9, 2008
3DU7
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BU of 3du7 by Molmil
Tubulin-colchicine-phomopsin A: Stathmin-like domain complex
分子名称: 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Cormier, A, Marchand, M, Ravelli, R.B, Knossow, M, Gigant, B.
登録日2008-07-17
公開日2008-10-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Structural insight into the inhibition of tubulin by vinca domain peptide ligands
Embo Rep., 9, 2008
1LG7
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BU of 1lg7 by Molmil
Crystal structure of Vesicular Stomatitis Virus Matrix Protein
分子名称: VSV matrix protein
著者Gaudier, M, Gaudin, Y, Knossow, M.
登録日2002-04-15
公開日2002-06-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal structure of vesicular stomatitis virus matrix protein.
EMBO J., 21, 2002
2GFB
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BU of 2gfb by Molmil
CRYSTAL STRUCTURE OF A CATALYTIC FAB HAVING ESTERASE-LIKE ACTIVITY
分子名称: IGG2A CNJ206 FAB (HEAVY CHAIN), IGG2A CNJ206 FAB (LIGHT CHAIN)
著者Golinelli-Pimpaneau, B, Knossow, M.
登録日1994-07-07
公開日1994-09-30
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of a catalytic antibody Fab with esterase-like activity.
Structure, 2, 1994
3N2K
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BU of 3n2k by Molmil
TUBULIN-NSC 613862: RB3 Stathmin-like domain complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Barbier, P, Dorleans, A, Devred, F, Sanz, L, Allegro, D, Alfonso, C, Knossow, M, Peyrot, V, Andreu, J.M.
登録日2010-05-18
公開日2010-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Stathmin and interfacial microtubule inhibitors recognize a naturally curved conformation of tubulin dimers.
J.Biol.Chem., 285, 2010
3N2G
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TUBULIN-NSC 613863: RB3 Stathmin-like domain complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Barbier, P, Dorleans, A, Devred, F, Sanz, L, Allegro, D, Alfonso, C, Knossow, M, Peyrot, V, Andreu, J.M.
登録日2010-05-18
公開日2010-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Stathmin and interfacial microtubule inhibitors recognize a naturally curved conformation of tubulin dimers.
J.Biol.Chem., 285, 2010
3UT5
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BU of 3ut5 by Molmil
Tubulin-Colchicine-Ustiloxin: Stathmin-like domain complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Ranaivoson, F.M, Gigant, B, Knossow, M.
登録日2011-11-25
公開日2012-08-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Structural plasticity of tubulin assembly probed by vinca-domain ligands.
Acta Crystallogr.,Sect.D, 68, 2012
4P40
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BU of 4p40 by Molmil
Chlamydia pneumoniae CopN
分子名称: CHLORIDE ION, CopN, DIMETHYLAMINE, ...
著者Nawrotek, A, Guimaraes, B.G, Knossow, M, Gigant, B.
登録日2014-03-10
公開日2014-07-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Biochemical and Structural Insights into Microtubule Perturbation by CopN from Chlamydia pneumoniae.
J.Biol.Chem., 289, 2014
4P3Z
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BU of 4p3z by Molmil
Chlamydia pneumoniae CopN (D29 construct)
分子名称: CopN, GLYCEROL, SULFATE ION
著者Nawrotek, A, Guimaraes, B.G, Knossow, M, Gigant, B.
登録日2014-03-10
公開日2014-07-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Biochemical and Structural Insights into Microtubule Perturbation by CopN from Chlamydia pneumoniae.
J.Biol.Chem., 289, 2014
1KNO
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BU of 1kno by Molmil
CRYSTAL STRUCTURE OF THE COMPLEX OF A CATALYTIC ANTIBODY FAB WITH A TRANSITION STATE ANALOG: STRUCTURAL SIMILARITIES IN ESTERASE-LIKE ABZYMES
分子名称: IGG2A FAB FRAGMENT CNJ206, METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTER, ZINC ION
著者Charbonnier, J.-B, Gigant, B, Knossow, M.
登録日1995-09-11
公開日1996-01-29
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of the complex of a catalytic antibody Fab fragment with a transition state analog: structural similarities in esterase-like catalytic antibodies.
Proc.Natl.Acad.Sci.USA, 92, 1995
1KEN
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BU of 1ken by Molmil
INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH AN ANTIBODY THAT PREVENTS THE HEMAGGLUTININ LOW PH FUSOGENIC TRANSITION
分子名称: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin HA1, hemagglutinin HA2, ...
著者Barbey-Martin, C, Gigant, B, Bizebard, T, Calder, L.J, Wharto, S.A, Skehel, J.J, Knossow, M.
登録日2001-11-16
公開日2002-04-24
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献An Antibody that Prevents the Hemagglutinin Low pH Fusogenic Transition
VIROLOGY, 294, 2002
1SQK
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CRYSTAL STRUCTURE OF CIBOULOT IN COMPLEX WITH SKELETAL ACTIN
分子名称: ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-DIPHOSPHATE, ...
著者Hertzog, M, Van Heijenoort, C, Didry, D, Gaudier, M, Gigant, B, Coutant, J, Didelot, G, Preat, T, Knossow, M, Guittet, E, Carlier, M.F.
登録日2004-03-19
公開日2004-06-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The beta-Thymosin/WH2 Domain; Structural Basis for the Switch from Inhibition to Promotion of Actin Assembly
Cell(Cambridge,Mass.), 117, 2004
4F6R
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BU of 4f6r by Molmil
Tubulin:Stathmin-like domain complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Designed ankyrin repeat protein (DARPIN) D2, GUANOSINE-5'-DIPHOSPHATE, ...
著者Gigant, B, Mignot, I, Knossow, M.
登録日2012-05-15
公開日2012-07-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Design and characterization of modular scaffolds for tubulin assembly.
J.Biol.Chem., 287, 2012
4EB6
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BU of 4eb6 by Molmil
Tubulin-Vinblastine: Stathmin-like complex
分子名称: (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Ranaivoson, F.M, Gigant, B, Knossow, M.
登録日2012-03-23
公開日2012-08-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.47 Å)
主引用文献Structural plasticity of tubulin assembly probed by vinca-domain ligands.
Acta Crystallogr.,Sect.D, 68, 2012
4F61
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Tubulin:Stathmin-like domain complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Gigant, B, Mignot, I, Knossow, M.
登録日2012-05-14
公開日2012-07-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (4.17 Å)
主引用文献Design and characterization of modular scaffolds for tubulin assembly.
J.Biol.Chem., 287, 2012
1EO8
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INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY (HEAVY CHAIN), ...
著者Fleury, D, Gigant, B, Daniels, R.S, Skehel, J.J, Knossow, M, Bizebard, T.
登録日2000-03-22
公開日2000-04-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural evidence for recognition of a single epitope by two distinct antibodies.
Proteins, 40, 2000

 

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