7PA2
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![BU of 7pa2 by Molmil](/molmil-images/mine/7pa2) | PARK7 with inhibitor 8RK64 | Descriptor: | (3~{S})-~{N}-[5-[2-[(azanylidene-$l^{4}-azanylidene)amino]ethanoyl]-6,7-dihydro-4~{H}-[1,3]thiazolo[5,4-c]pyridin-2-yl]-1-(iminomethyl)pyrrolidine-3-carboxamide, Parkinson disease protein 7 | Authors: | Kim, R.Q, Jia, Y, Sapmaz, A, Geurink, P.P. | Deposit date: | 2021-07-28 | Release date: | 2022-08-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.21 Å) | Cite: | Chemical Toolkit for PARK7: Potent, Selective, and High-Throughput. J.Med.Chem., 65, 2022
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7PA3
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![BU of 7pa3 by Molmil](/molmil-images/mine/7pa3) | PARK7 with covalent inhibitor JYQ-88 | Descriptor: | (3~{S})-~{N}-[5-[2-[(azanylidene-$l^{4}-azanylidene)amino]ethanoyl]-6,7-dihydro-4~{H}-[1,3]thiazolo[5,4-c]pyridin-2-yl]-1-(iminomethyl)pyrrolidine-3-carboxamide, Parkinson disease protein 7 | Authors: | Kim, R.Q, Jia, Y, Sapmaz, A, Geurink, P.P. | Deposit date: | 2021-07-28 | Release date: | 2022-08-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Chemical Toolkit for PARK7: Potent, Selective, and High-Throughput. J.Med.Chem., 65, 2022
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4BMZ
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![BU of 4bmz by Molmil](/molmil-images/mine/4bmz) | Structure of futalosine hydrolase mutant of Helicobacter pylori strain 26695 | Descriptor: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, MTA/SAH NUCLEOSIDASE | Authors: | Kim, R.Q, Offen, W.A, Stubbs, K.A, Davies, G.J. | Deposit date: | 2013-05-12 | Release date: | 2013-09-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Structural Enzymology of Helicobacter Pylori Methylthioadenosine Nucleosidase in the Futalosine Pathway Acta Crystallogr.,Sect.D, 70, 2014
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4BN0
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![BU of 4bn0 by Molmil](/molmil-images/mine/4bn0) | Structure of futalosine hydrolase mutant of Helicobacter pylori strain 26695 | Descriptor: | MTA/SAH NUCLEOSIDASE | Authors: | Kim, R.Q, Offen, W.A, Stubbs, K.A, Davies, G.J. | Deposit date: | 2013-05-12 | Release date: | 2013-09-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Structural Enzymology of Helicobacter Pylori Methylthioadenosine Nucleosidase in the Futalosine Pathway Acta Crystallogr.,Sect.D, 70, 2014
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4BMY
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![BU of 4bmy by Molmil](/molmil-images/mine/4bmy) | Structure of futalosine hydrolase mutant of Helicobacter pylori strain 26695 | Descriptor: | MTA/SAH NUCLEOSIDASE, SULFATE ION | Authors: | Kim, R.Q, Offen, W.A, Stubbs, K.A, Davies, G.J. | Deposit date: | 2013-05-12 | Release date: | 2013-09-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural Enzymology of Helicobacter Pylori Methylthioadenosine Nucleosidase in the Futalosine Pathway Acta Crystallogr.,Sect.D, 70, 2014
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4BMX
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![BU of 4bmx by Molmil](/molmil-images/mine/4bmx) | Native structure of futalosine hydrolase of Helicobacter pylori strain 26695 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENINE, MTA/SAH NUCLEOSIDASE | Authors: | Kim, R.Q, Offen, W.A, Stubbs, K.A, Davies, G.J. | Deposit date: | 2013-05-12 | Release date: | 2013-09-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Structural Enzymology of Helicobacter Pylori Methylthioadenosine Nucleosidase in the Futalosine Pathway Acta Crystallogr.,Sect.D, 70, 2014
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5FWI
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![BU of 5fwi by Molmil](/molmil-images/mine/5fwi) | |
6T9D
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![BU of 6t9d by Molmil](/molmil-images/mine/6t9d) | Crystal structure of a bispecific DutaFab in complex with human VEGF121 | Descriptor: | VP mat DutaFab VH chain, VP mat DutaFab VL chain, Vascular endothelial growth factor A | Authors: | Kimbung, R, Logan, D.T, Beckmann, R, Jensen, K, Speck, J, Fenn, S, Kettenberger, H. | Deposit date: | 2019-10-28 | Release date: | 2020-12-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.905 Å) | Cite: | DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously. Nat Commun, 12, 2021
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6T9E
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![BU of 6t9e by Molmil](/molmil-images/mine/6t9e) | Crystal structure of a bispecific DutaFab in complex with human PDGF | Descriptor: | DutaFab mat VH chain, DutaFab mat VL chain, Platelet-derived growth factor subunit B | Authors: | Kimbung, R, Logan, D.T, Beckmann, R, Jensen, K, Speck, J, Fenn, S, Kettenberger, H. | Deposit date: | 2019-10-28 | Release date: | 2020-12-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.989 Å) | Cite: | DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously. Nat Commun, 12, 2021
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1KJY
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![BU of 1kjy by Molmil](/molmil-images/mine/1kjy) | Crystal Structure of Human G[alpha]i1 Bound to the GoLoco Motif of RGS14 | Descriptor: | CESIUM ION, GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-1 SUBUNIT, ... | Authors: | Kimple, R.J, Kimple, M.E, Betts, L, Sondek, J, Siderovski, D.P. | Deposit date: | 2001-12-05 | Release date: | 2002-05-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits. Nature, 416, 2002
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6CDX
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![BU of 6cdx by Molmil](/molmil-images/mine/6cdx) | High-resolution crystal structure of fluoropropylated cystine knot, binding to alpha-5 beta-6 integrin | Descriptor: | cystine knot (fluoropropylated) | Authors: | Kimura, R, Nix, J, Bongura, C, Chakraborti, S, Gambhir, S, Filipp, F.V. | Deposit date: | 2018-02-09 | Release date: | 2019-08-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Evaluation of integrin alpha v beta6cystine knot PET tracers to detect cancer and idiopathic pulmonary fibrosis. Nat Commun, 10, 2019
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1MRZ
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![BU of 1mrz by Molmil](/molmil-images/mine/1mrz) | Crystal structure of a flavin binding protein from Thermotoga Maritima, TM379 | Descriptor: | CITRIC ACID, Riboflavin kinase/FMN adenylyltransferase | Authors: | Wang, W, Kim, R, Jancarik, J, Yokota, H, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) | Deposit date: | 2002-09-19 | Release date: | 2003-09-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of a flavin-binding protein from Thermotoga Maritima Proteins, 52, 2003
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1EKE
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![BU of 1eke by Molmil](/molmil-images/mine/1eke) | CRYSTAL STRUCTURE OF CLASS II RIBONUCLEASE H (RNASE HII) WITH MES LIGAND | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, RIBONUCLEASE HII | Authors: | Lai, L.H, Yokota, H, Hung, L.W, Kim, R, Kim, S.H, Berkeley Structural Genomics Center (BSGC) | Deposit date: | 2000-03-07 | Release date: | 2000-09-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of archaeal RNase HII: a homologue of human major RNase H Structure, 8, 2000
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1N0F
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![BU of 1n0f by Molmil](/molmil-images/mine/1n0f) | CRYSTAL STRUCTURE OF A CELL DIVISION AND CELL WALL BIOSYNTHESIS PROTEIN UPF0040 FROM MYCOPLASMA PNEUMONIAE: INDICATION OF A NOVEL FOLD WITH A POSSIBLE NEW CONSERVED SEQUENCE MOTIF | Descriptor: | Protein mraZ | Authors: | Chen, S, Jancrick, J, Yokota, H, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) | Deposit date: | 2002-10-13 | Release date: | 2003-10-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of a protein associated with cell division from Mycoplasma pneumoniae (GI: 13508053): a novel fold with a conserved sequence motif. Proteins, 55, 2004
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1N0E
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![BU of 1n0e by Molmil](/molmil-images/mine/1n0e) | CRYSTAL STRUCTURE OF A CELL DIVISION AND CELL WALL BIOSYNTHESIS PROTEIN UPF0040 FROM MYCOPLASMA PNEUMONIAE: INDICATION OF A NOVEL FOLD WITH A POSSIBLE NEW CONSERVED SEQUENCE MOTIF | Descriptor: | Protein mraZ | Authors: | Chen, S, Jancrick, J, Yokota, H, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) | Deposit date: | 2002-10-13 | Release date: | 2003-10-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of a protein associated with cell division from Mycoplasma pneumoniae (GI: 13508053): a novel fold with a conserved sequence motif. Proteins, 55, 2004
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1N0G
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![BU of 1n0g by Molmil](/molmil-images/mine/1n0g) | Crystal Structure of A Cell Division and Cell Wall Biosynthesis Protein UPF0040 from Mycoplasma pneumoniae: Indication of A Novel Fold with A Possible New Conserved Sequence Motif | Descriptor: | Protein mraZ | Authors: | Chen, S, Jancarik, J, Yokota, H, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) | Deposit date: | 2002-10-13 | Release date: | 2003-10-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of a protein associated with cell division from Mycoplasma pneumoniae (GI: 13508053): a novel fold with a conserved sequence motif. Proteins, 55, 2004
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4R3R
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![BU of 4r3r by Molmil](/molmil-images/mine/4r3r) | Crystal structures of EGFR in complex with Mig6 | Descriptor: | Epidermal growth factor receptor, peptide from ERBB receptor feedback inhibitor 1' | Authors: | Park, E, Kim, N, Yi, Z, Cho, A, Kim, K, Ficarro, S.B, Park, A, Park, W.Y, Murray, B, Meyerson, M, Beroukim, R, Marto, J.A, Cho, J, Eck, M.J. | Deposit date: | 2014-08-17 | Release date: | 2015-08-12 | Last modified: | 2015-09-16 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6. Nat.Struct.Mol.Biol., 22, 2015
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4R3P
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![BU of 4r3p by Molmil](/molmil-images/mine/4r3p) | Crystal structures of EGFR in complex with Mig6 | Descriptor: | Epidermal growth factor receptor, peptide from ERBB receptor feedback inhibitor 1 | Authors: | Park, E, Kim, N, Yi, Z, Cho, A, Kim, K, Ficarro, S.B, Park, A, Park, W.Y, Murray, B, Meyerson, M, Beroukim, R, Marto, J.A, Cho, J, Eck, M.J. | Deposit date: | 2014-08-17 | Release date: | 2015-08-12 | Last modified: | 2015-09-16 | Method: | X-RAY DIFFRACTION (2.905 Å) | Cite: | Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6. Nat.Struct.Mol.Biol., 22, 2015
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1EIF
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![BU of 1eif by Molmil](/molmil-images/mine/1eif) | EUKARYOTIC TRANSLATION INITIATION FACTOR 5A FROM METHANOCOCCUS JANNASCHII | Descriptor: | EUKARYOTIC TRANSLATION INITIATION FACTOR 5A | Authors: | Kim, K.K, Hung, L.W, Yokota, H, Kim, R, Kim, S.H. | Deposit date: | 1998-07-29 | Release date: | 1998-10-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structures of eukaryotic translation initiation factor 5A from Methanococcus jannaschii at 1.8 A resolution. Proc.Natl.Acad.Sci.USA, 95, 1998
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1FBN
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![BU of 1fbn by Molmil](/molmil-images/mine/1fbn) | CRYSTAL STRUCTURE OF A FIBRILLARIN HOMOLOGUE FROM METHANOCOCCUS JANNASCHII, A HYPERTHERMOPHILE, AT 1.6 A | Descriptor: | MJ FIBRILLARIN HOMOLOGUE | Authors: | Wang, H, Boisvert, D, Kim, K.K, Kim, R, Kim, S.H, Berkeley Structural Genomics Center (BSGC) | Deposit date: | 1999-04-25 | Release date: | 2000-04-26 | Last modified: | 2014-11-26 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of a fibrillarin homologue from Methanococcus jannaschii, a hyperthermophile, at 1.6 A resolution. EMBO J., 19, 2000
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2EIF
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![BU of 2eif by Molmil](/molmil-images/mine/2eif) | Eukaryotic translation initiation factor 5A from Methanococcus jannaschii | Descriptor: | PROTEIN (EUKARYOTIC TRANSLATION INITIATION FACTOR 5A) | Authors: | Kim, K.K, Hung, L.W, Kim, R, Kim, S.H, Berkeley Structural Genomics Center (BSGC) | Deposit date: | 1998-10-12 | Release date: | 1999-10-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structures of eukaryotic translation initiation factor 5A from Methanococcus jannaschii at 1.8 A resolution. Proc.Natl.Acad.Sci.USA, 95, 1998
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1F5S
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![BU of 1f5s by Molmil](/molmil-images/mine/1f5s) | CRYSTAL STRUCTURE OF PHOSPHOSERINE PHOSPHATASE FROM METHANOCOCCUS JANNASCHII | Descriptor: | MAGNESIUM ION, PHOSPHATE ION, PHOSPHOSERINE PHOSPHATASE (PSP) | Authors: | Wang, W, Kim, R, Jancarik, J, Yokota, H, Kim, S.H, Berkeley Structural Genomics Center (BSGC) | Deposit date: | 2000-06-15 | Release date: | 2001-06-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of phosphoserine phosphatase from Methanococcus jannaschii, a hyperthermophile, at 1.8 A resolution. Structure, 9, 2001
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1G2I
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![BU of 1g2i by Molmil](/molmil-images/mine/1g2i) | CRYSTAL STRUCTURE OF A NOVEL INTRACELLULAR PROTEASE FROM PYROCOCCUS HORIKOSHII AT 2 A RESOLUTION | Descriptor: | PROTEASE I, SULFATE ION | Authors: | Du, X, Choi, I.-G, Kim, R, Jancarik, J, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) | Deposit date: | 2000-10-19 | Release date: | 2000-11-08 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of an intracellular protease from Pyrococcus horikoshii at 2-A resolution. Proc.Natl.Acad.Sci.USA, 97, 2000
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1STZ
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![BU of 1stz by Molmil](/molmil-images/mine/1stz) | Crystal structure of a hypothetical protein at 2.2 A resolution | Descriptor: | Heat-inducible transcription repressor hrcA homolog | Authors: | Liu, J, Adams, P.D, Shin, D.-H, Huang, C, Yokota, H, Jancarik, J, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) | Deposit date: | 2004-03-25 | Release date: | 2004-08-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a heat-inducible transcriptional repressor HrcA from Thermotoga maritima: structural insight into DNA binding and dimerization. J.Mol.Biol., 350, 2005
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1Q8C
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![BU of 1q8c by Molmil](/molmil-images/mine/1q8c) | A conserved hypothetical protein from Mycoplasma genitalium shows structural homology to NusB proteins | Descriptor: | CHLORIDE ION, Hypothetical protein MG027, IODIDE ION, ... | Authors: | Liu, J, Yokota, H, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) | Deposit date: | 2003-08-20 | Release date: | 2003-09-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A conserved hypothetical protein from Mycoplasma genitalium shows structural homology to nusb proteins Proteins, 55, 2004
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