Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 55 件
1D8G
DownloadVisualize
BU of 1d8g by Molmil
ULTRAHIGH RESOLUTION CRYSTAL STRUCTURE OF B-DNA DECAMER D(CCAGTACTGG)
分子名称: 5'-D(*CP*CP*AP*GP*TP*AP*CP*TP*GP*GP*)-3', CALCIUM ION
著者Kielkopf, C.L, Ding, S, Kuhn, P, Rees, D.C.
登録日1999-10-23
公開日2000-02-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (0.74 Å)
主引用文献Conformational flexibility of B-DNA at 0.74 A resolution: d(CCAGTACTGG)(2).
J.Mol.Biol., 296, 2000
1CVX
DownloadVisualize
BU of 1cvx by Molmil
CRYSTAL STRUCTURE OF POLYAMIDE DIMER (IMPYHPPYBETADP)2 BOUND TO B-DNA DECAMER CCAGATCTGG
分子名称: 5'-D(*CP*CP*AP*GP*AP*TP*CP*TP*GP*G)-3', HYDROXYPYRROLE-IMIDAZOLE-PYRROLE POLYAMIDE
著者Kielkopf, C.L, Bremer, R.E, White, S, Baird, E.E, Dervan, P.B, Rees, D.C.
登録日1999-08-24
公開日2000-01-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structural effects of DNA sequence on T.A recognition by hydroxypyrrole/pyrrole pairs in the minor groove.
J.Mol.Biol., 295, 2000
1CVY
DownloadVisualize
BU of 1cvy by Molmil
CRYSTAL STRUCTURE OF POLYAMIDE DIMER (IMPYPYPYBETADP)2 BOUND TO CCAGATCTGG
分子名称: 5'-D(*CP*CP*AP*GP*AP*TP*CP*TP*GP*G)-3', IMIDAZOLE-PYRROLE POLYAMIDE
著者Kielkopf, C.L, Bremer, R.E, White, S, Baird, E.E, Dervan, P.B, Rees, D.C.
登録日1999-08-24
公開日2000-01-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural effects of DNA sequence on T.A recognition by hydroxypyrrole/pyrrole pairs in the minor groove.
J.Mol.Biol., 295, 2000
365D
DownloadVisualize
BU of 365d by Molmil
STRUCTURAL BASIS FOR G C RECOGNITION IN THE DNA MINOR GROOVE
分子名称: DNA (5'-D(*CP*CP*AP*GP*GP*(CBR)P*CP*TP*GP*G)-3'), IMIDAZOLE-PYRROLE POLYAMIDE
著者Kielkopf, C.L, Baird, E.E, Dervan, P.B, Rees, D.C.
登録日1997-12-17
公開日1998-02-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for G.C recognition in the DNA minor groove.
Nat.Struct.Biol., 5, 1998
1JG8
DownloadVisualize
BU of 1jg8 by Molmil
Crystal Structure of Threonine Aldolase (Low-specificity)
分子名称: CALCIUM ION, L-allo-threonine aldolase, SODIUM ION
著者Kielkopf, C.L, Bonanno, J, Ray, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2001-06-23
公開日2001-07-04
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Low-specificity Threonine Aldolase, a Key Enzyme in Glycine Biosynthesis
To be published
1JMT
DownloadVisualize
BU of 1jmt by Molmil
X-ray Structure of a Core U2AF65/U2AF35 Heterodimer
分子名称: HEXANE-1,6-DIOL, SPLICING FACTOR U2AF 35 KDA SUBUNIT, SPLICING FACTOR U2AF 65 KDA SUBUNIT
著者Kielkopf, C.L, Rodionova, N.A, Green, M.R, Burley, S.K.
登録日2001-07-19
公開日2001-09-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A novel peptide recognition mode revealed by the X-ray structure of a core U2AF35/U2AF65 heterodimer.
Cell(Cambridge,Mass.), 106, 2001
1LW4
DownloadVisualize
BU of 1lw4 by Molmil
X-ray structure of L-Threonine Aldolase (low-specificity) in complex with L-allo-threonine
分子名称: 3-HYDROXY-2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-BUTYRIC ACID, CALCIUM ION, CHLORIDE ION, ...
著者Kielkopf, C.L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2002-05-30
公開日2002-12-11
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献X-ray Structures of Threonine Aldolase Complexes: Structural Basis of Substrate Recognition
Biochemistry, 41, 2002
1LW5
DownloadVisualize
BU of 1lw5 by Molmil
X-ray structure of L-Threonine Aldolase (low-specificity) in complex with glycine
分子名称: CALCIUM ION, CHLORIDE ION, L-allo-threonine aldolase, ...
著者Kielkopf, C.L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2002-05-30
公開日2002-12-11
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献X-ray Structures of Threonine Aldolase Complexes: Structural Basis of Substrate Recognition
Biochemistry, 41, 2002
408D
DownloadVisualize
BU of 408d by Molmil
STRUCTURAL BASIS FOR RECOGNITION OF A-T AND T-A BASE PAIRS IN THE MINOR GROOVE OF B-DNA
分子名称: DNA (5'-D(*CP*CP*AP*GP*TP*AP*CP*TP*GP*G)-3'), IMIDAZOLE-PYRROLE POLYAMIDE
著者Kielkopf, C.L, White, S, Szewczyk, J.W, Turner, J.M, Baird, E.E, Dervan, P.B, Rees, D.C.
登録日1998-06-24
公開日1998-10-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A structural basis for recognition of A.T and T.A base pairs in the minor groove of B-DNA.
Science, 282, 1998
454D
DownloadVisualize
BU of 454d by Molmil
INTERCALATION AND MAJOR GROOVE RECOGNITION IN THE 1.2 A RESOLUTION CRYSTAL STRUCTURE OF RH[ME2TRIEN]PHI BOUND TO 5'-G(5IU)TGCAAC-3'
分子名称: 5'-D(*GP*(5IU)P*TP*GP*CP*AP*AP*C)-3', DELTA-ALPHA-RH[2R,9R-DIAMINO-4,7-DIAZADECANE]9,10-PHENANTHRENEQUINONE DIIMINE
著者Kielkopf, C.L, Erkkila, K.E, Hudson, B.P, Barton, J.K, Rees, D.C.
登録日1999-03-03
公開日2000-02-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structure of a photoactive rhodium complex intercalated into DNA.
Nat.Struct.Biol., 7, 2000
1M6S
DownloadVisualize
BU of 1m6s by Molmil
Crystal Structure Of Threonine Aldolase
分子名称: CALCIUM ION, CHLORIDE ION, L-allo-threonine aldolase
著者Burley, S.K, Kielkopf, C.L.
登録日2002-07-17
公開日2002-12-11
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-ray Structures of Threonine Aldolase Complexes: Structural Basis of Substrate Recognition
Biochemistry, 41, 2002
2G4B
DownloadVisualize
BU of 2g4b by Molmil
Structure of U2AF65 variant with polyuridine tract
分子名称: 1,4-DIETHYLENE DIOXIDE, 5'-R(P*UP*UP*UP*UP*UP*UP*U)-3', Splicing factor U2AF 65 kDa subunit
著者Sickmier, E.A, Kielkopf, C.L.
登録日2006-02-21
公開日2006-07-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of polypyrimidine tract recognition by the essential splicing factor U2AF65.
Mol.Cell, 23, 2006
4OZ0
DownloadVisualize
BU of 4oz0 by Molmil
Crystal structure of human CAPERalpha U2AF homology motif (apo-state)
分子名称: CHLORIDE ION, RNA-binding protein 39
著者Loerch, S, Kielkopf, C.L.
登録日2014-02-13
公開日2014-05-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Cancer-relevant splicing factor CAPER alpha engages the essential splicing factor SF3b155 in a specific ternary complex.
J.Biol.Chem., 289, 2014
2HZC
DownloadVisualize
BU of 2hzc by Molmil
Crystal structure of the N-terminal RRM of the U2AF large subunit
分子名称: HEXAETHYLENE GLYCOL, Splicing factor U2AF 65 kDa subunit, ZINC ION
著者Thickman, K.R, Sickmier, E.A, Kielkopf, C.L.
登録日2006-08-08
公開日2006-08-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Alternative Conformations at the RNA-binding Surface of the N-terminal U2AF(65) RNA Recognition Motif.
J.Mol.Biol., 366, 2007
1XCB
DownloadVisualize
BU of 1xcb by Molmil
X-ray Structure of a Rex-Family Repressor/NADH Complex from Thermus Aquaticus
分子名称: CALCIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Redox-sensing transcriptional repressor rex
著者Sickmier, E.A, Brekasis, D, Paranawithana, S, Bonanno, J.B, Burley, S.K, Paget, M.S, Kielkopf, C.L, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2004-09-01
公開日2004-09-28
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献X-Ray Structure of a Rex-Family Repressor/NADH Complex: Insights into the Mechanism of Redox Sensing
Structure, 13, 2005
2OKS
DownloadVisualize
BU of 2oks by Molmil
X-ray Structure of a DNA Repair Substrate Containing an Alkyl Interstrand Crosslink at 1.65 Resolution
分子名称: 5'-D(*CP*CP*AP*AP*(C34)P*GP*TP*TP*GP*G)-3', CALCIUM ION
著者Swenson, M.C, Paranawithana, S.R, Miller, P.S, Kielkopf, C.L.
登録日2007-01-17
公開日2007-02-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of a DNA repair substrate containing an alkyl interstrand cross-link at 1.65 a resolution.
Biochemistry, 46, 2007
4FXX
DownloadVisualize
BU of 4fxx by Molmil
Structure of SF1 coiled-coil domain
分子名称: IMIDAZOLE, MALONATE ION, Splicing factor 1
著者Gupta, A, Bauer, W.J, Wang, W, Kielkopf, C.L.
登録日2012-07-03
公開日2013-01-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4801 Å)
主引用文献Structure of Phosphorylated SF1 Bound to U2AF(65) in an Essential Splicing Factor Complex.
Structure, 21, 2013
4FXW
DownloadVisualize
BU of 4fxw by Molmil
Structure of phosphorylated SF1 complex with U2AF65-UHM domain
分子名称: SULFATE ION, Splicing factor 1, Splicing factor U2AF 65 kDa subunit
著者Wang, W, Bauer, W.J, Wedekind, J.E, Kielkopf, C.L.
登録日2012-07-03
公開日2013-01-16
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structure of Phosphorylated SF1 Bound to U2AF(65) in an Essential Splicing Factor Complex.
Structure, 21, 2013
6XLW
DownloadVisualize
BU of 6xlw by Molmil
Crystal structure of U2AF65 bound to AdML splice site sequence
分子名称: DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(P*UP*UP*(UD)P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), GLYCEROL, ...
著者Maji, D, Jenkins, J.L, Kielkopf, C.L.
登録日2020-06-29
公開日2020-10-07
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing.
J.Biol.Chem., 295, 2020
5W0H
DownloadVisualize
BU of 5w0h by Molmil
Structure of U2AF65 (U2AF2) RRM2 at 1.11 Angstrom Resolution
分子名称: Splicing factor U2AF 65 kDa subunit
著者Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L.
登録日2017-05-30
公開日2018-04-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.11 Å)
主引用文献Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs.
Biochemistry, 56, 2017
5W0G
DownloadVisualize
BU of 5w0g by Molmil
Structure of U2AF65 (U2AF2) RRM1 at 1.07 resolution
分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ACETATE ION, Splicing factor U2AF 65 kDa subunit, ...
著者Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L.
登録日2017-05-30
公開日2018-04-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.07 Å)
主引用文献Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs.
Biochemistry, 56, 2017
7S3A
DownloadVisualize
BU of 7s3a by Molmil
Crystal structure of intact U2AF65 RRM-region bound to AdML-C5 oligonucleotide
分子名称: DNA/RNA (5'-R(P*UP*UP*(UD)P*CP*U)-D(P*(BRU))-R(P*CP*C)-3'), SODIUM ION, Splicing factor U2AF 65 kDa subunit
著者Jenkins, J.L, Henderson, S, Kielkopf, C.L.
登録日2021-09-05
公開日2022-05-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.
Nucleic Acids Res., 50, 2022
7SN6
DownloadVisualize
BU of 7sn6 by Molmil
U2AF65 UHM BOUND TO SF3B155 ULM5
分子名称: ISOPROPYL ALCOHOL, Splicing factor 3B subunit 1, Splicing factor U2AF 65 kDa subunit
著者Loerch, S, Jenkins, J.L, Kielkopf, C.L.
登録日2021-10-27
公開日2022-07-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A UHM-ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing.
J.Biol.Chem., 298, 2022
3BS9
DownloadVisualize
BU of 3bs9 by Molmil
X-ray structure of human TIA-1 RRM2
分子名称: IODIDE ION, Nucleolysin TIA-1 isoform p40
著者Kumar, A.O, Kielkopf, C.L.
登録日2007-12-22
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of the central RNA recognition motif of human TIA-1 at 1.95A resolution.
Biochem.Biophys.Res.Commun., 367, 2008
3CGR
DownloadVisualize
BU of 3cgr by Molmil
X-ray structure containing the pseudouridylated U2 snRNA and intron branch site consensus sequences
分子名称: RNA (5'-R(*CP*GP*CP*AP*CP*UP*AP*AP*CP*CP*GP*CP*G)-3'), RNA (5'-R(*GP*CP*GP*CP*GP*GP*(PSU)P*AP*GP*UP*GP*C)-3'), SULFATE ION
著者Lin, Y, Kielkopf, C.L.
登録日2008-03-06
公開日2008-07-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-ray structures of U2 snRNA-branchpoint duplexes containing conserved pseudouridines.
Biochemistry, 47, 2008

 

123>

222415

件を2024-07-10に公開中

PDB statisticsPDBj update infoContact PDBjnumon