7SCQ
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7SC6
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7SAM
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1KH6
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![BU of 1kh6 by Molmil](/molmil-images/mine/1kh6) | Crystal Structure of an RNA Tertiary Domain Essential to HCV IRES-mediated Translation Initiation. | Descriptor: | JIIIabc | Authors: | Kieft, J.S, Zhou, K, Grech, A, Jubin, R, Doudna, J.A. | Deposit date: | 2001-11-29 | Release date: | 2002-04-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of an RNA tertiary domain essential to HCV IRES-mediated translation initiation. Nat.Struct.Biol., 9, 2002
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1AJF
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3B31
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![BU of 3b31 by Molmil](/molmil-images/mine/3b31) | Crystal structure of domain III of the Cricket Paralysis Virus IRES RNA | Descriptor: | IRIDIUM HEXAMMINE ION, PHOSPHATE ION, RNA (29-MER), ... | Authors: | Kieft, J.S, Costantino, D.A, Pfingsten, J.S, Rambo, R.P. | Deposit date: | 2007-10-19 | Release date: | 2007-12-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | tRNA-mRNA mimicry drives translation initiation from a viral IRES. Nat.Struct.Mol.Biol., 15, 2008
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3MJB
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![BU of 3mjb by Molmil](/molmil-images/mine/3mjb) | Cricket Paralysis Virus IGR IRES Domain 3 RNA bound to sulfate | Descriptor: | Domain 3 of the cricket paralysis virus intergenic region IRES RNA, RNA (5'-R(P*UP*AP*AP*GP*AP*AP*AP*UP*UP*UP*AP*CP*CP*U)-3'), SULFATE ION | Authors: | Kieft, J.S, Golden, B.L, Costantino, D.A, Chase, E. | Deposit date: | 2010-04-12 | Release date: | 2010-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Identification and characterization of anion binding sites in RNA. Rna, 16, 2010
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3MJ3
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![BU of 3mj3 by Molmil](/molmil-images/mine/3mj3) | Cricket Paralysis Virus IGR IRES Domain 3 RNA bound to selenate | Descriptor: | Domain 3 of the cricket paralysis virus intergenic region IRES RNA, RNA (5'-R(P*UP*AP*AP*GP*AP*AP*AP*UP*UP*UP*AP*CP*CP*U)-3'), SELENATE ION | Authors: | Kieft, J.S, Chase, E, Costantino, D.A, Golden, B.L. | Deposit date: | 2010-04-12 | Release date: | 2010-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Identification and characterization of anion binding sites in RNA. Rna, 16, 2010
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3MJA
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![BU of 3mja by Molmil](/molmil-images/mine/3mja) | Cricket Paralysis Virus IGR IRES Domain 3 RNA bound to selenate, structure #2 | Descriptor: | Domain 3 of the cricket paralysis virus intergenic region IRES RNA, RNA (5'-R(P*UP*AP*AP*GP*AP*AP*AP*UP*UP*UP*AP*CP*CP*U)-3'), SELENATE ION | Authors: | Kieft, J.S, Golden, B.L, Costantino, D.A, Chase, E. | Deposit date: | 2010-04-12 | Release date: | 2010-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Identification and characterization of anion binding sites in RNA. Rna, 16, 2010
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4V83
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![BU of 4v83 by Molmil](/molmil-images/mine/4v83) | Crystal structure of a complex containing domain 3 from the PSIV IGR IRES RNA bound to the 70S ribosome. | Descriptor: | 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Zhu, J, Korostelev, A, Costantino, D, Noller, H.F, Kieft, J.S. | Deposit date: | 2010-12-13 | Release date: | 2014-07-09 | Last modified: | 2014-12-10 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome. Proc.Natl.Acad.Sci.USA, 108, 2011
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4V84
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![BU of 4v84 by Molmil](/molmil-images/mine/4v84) | Crystal structure of a complex containing domain 3 of CrPV IGR IRES RNA bound to the 70S ribosome. | Descriptor: | 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Zhu, J, Korostelev, A, Costantino, D, Noller, H.F, Kieft, J.S. | Deposit date: | 2010-12-13 | Release date: | 2014-07-09 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome. Proc.Natl.Acad.Sci.USA, 108, 2011
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4PQV
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![BU of 4pqv by Molmil](/molmil-images/mine/4pqv) | Crystal structure of an Xrn1-resistant RNA from the 3' untranslated region of a flavivirus (Murray Valley Encephalitis virus) | Descriptor: | MAGNESIUM ION, XRN1-resistant flaviviral RNA | Authors: | Chapman, E.G, Costantino, D.A, Rabe, J.L, Moon, S.L, Wilusz, J, Nix, J.C, Kieft, J.S. | Deposit date: | 2014-03-04 | Release date: | 2014-04-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.463 Å) | Cite: | The structural basis of pathogenic subgenomic flavivirus RNA (sfRNA) production. Science, 344, 2014
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4P5J
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![BU of 4p5j by Molmil](/molmil-images/mine/4p5j) | Crystal structure of the tRNA-like structure from Turnip Yellow Mosaic Virus (TYMV), a tRNA mimicking RNA | Descriptor: | IRIDIUM HEXAMMINE ION, MAGNESIUM ION, SPERMINE, ... | Authors: | Colussi, T.M, Costantino, D.A, Hammond, J.A, Ruehle, G.M, Nix, J.C, Kieft, J.S. | Deposit date: | 2014-03-17 | Release date: | 2014-06-04 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9912 Å) | Cite: | The structural basis of transfer RNA mimicry and conformational plasticity by a viral RNA. Nature, 511, 2014
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7JJU
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![BU of 7jju by Molmil](/molmil-images/mine/7jju) | Crystal structure of en exoribonuclease-resistant RNA (xrRNA) from Potato leafroll virus (PLRV) | Descriptor: | CACODYLATE ION, Guanidinium, IRIDIUM HEXAMMINE ION, ... | Authors: | Steckelberg, A.-L, Vicens, Q, Auffinger, P, Costantino, D.C, Nix, J.C, Kieft, J.S. | Deposit date: | 2020-07-27 | Release date: | 2020-09-09 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.604 Å) | Cite: | The crystal structure of a Polerovirus exoribonuclease-resistant RNA shows how diverse sequences are integrated into a conserved fold. Rna, 26, 2020
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8FRU
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![BU of 8fru by Molmil](/molmil-images/mine/8fru) | 60S subunit of the Giardia lamblia 80S ribosome | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Eiler, D.R, Wimberly, B.T, Bilodeau, D.Y, Rissland, O.S, Kieft, J.S. | Deposit date: | 2023-01-08 | Release date: | 2024-01-31 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.49 Å) | Cite: | The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function. Structure, 32, 2024
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8G4S
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![BU of 8g4s by Molmil](/molmil-images/mine/8g4s) | 40S ribosomal subunit of the 80S Giardia intestinalis assemblage A ribosome with Emetine bound in V2 conformation with mRNA and three tRNAs. | Descriptor: | 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S25, ... | Authors: | Eiler, D.R, Wimberly, B.T, Bilodeau, D.Y, Rissland, O.S, Kieft, J.S. | Deposit date: | 2023-02-10 | Release date: | 2024-01-31 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function. Structure, 32, 2024
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8FVY
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![BU of 8fvy by Molmil](/molmil-images/mine/8fvy) | 40S subunit of the Giardia lamblia 80S ribosome | Descriptor: | 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S25, ... | Authors: | Eiler, D.R, Wimberly, B.T, Bilodeau, D.Y, Rissland, O.S, Kieft, J.S. | Deposit date: | 2023-01-20 | Release date: | 2024-01-24 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.94 Å) | Cite: | The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function. Structure, 32, 2024
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7UVT
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2IL9
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5TPY
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![BU of 5tpy by Molmil](/molmil-images/mine/5tpy) | Crystal structure of an exonuclease resistant RNA from Zika virus | Descriptor: | HEXANE-1,6-DIOL, MAGNESIUM ION, RNA (71-MER) | Authors: | Akiyama, B.M, Laurence, H.M, Massey, A.R, Costantino, D.A, Xie, X, Yang, Y, Shi, P.-Y, Nix, J.C, Beckham, J.D, Kieft, J.S. | Deposit date: | 2016-10-21 | Release date: | 2016-12-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.805 Å) | Cite: | Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease. Science, 354, 2016
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6MJ0
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![BU of 6mj0 by Molmil](/molmil-images/mine/6mj0) | Crystal structure of the complete turnip yellow mosaic virus 3'UTR | Descriptor: | RNA (101-MER) | Authors: | Hartwick, E.W, Costantino, D.A, MacFadden, A, Nix, J.C, Tian, S, Das, R, Kieft, J.S. | Deposit date: | 2018-09-20 | Release date: | 2019-01-09 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Ribosome-induced RNA conformational changes in a viral 3'-UTR sense and regulate translation levels. Nat Commun, 9, 2018
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7K16
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![BU of 7k16 by Molmil](/molmil-images/mine/7k16) | Tamana Bat Virus xrRNA1 | Descriptor: | MAGNESIUM ION, RNA (51-MER), SODIUM ION | Authors: | Jones, R.A, Kieft, J.S. | Deposit date: | 2020-09-07 | Release date: | 2020-10-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Different tertiary interactions create the same important 3D features in a distinct flavivirus xrRNA. Rna, 27, 2021
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7KGA
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![BU of 7kga by Molmil](/molmil-images/mine/7kga) | Crystal structure of a mosquito-borne flavivirus dumbbell RNA | Descriptor: | IRIDIUM HEXAMMINE ION, RNA (90-MER) | Authors: | Akiyama, B.M, Graham, M.E, O'Donoghue, Z, Beckham, J.D, Kieft, J.S. | Deposit date: | 2020-10-16 | Release date: | 2021-06-23 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Three-dimensional structure of a flavivirus dumbbell RNA reveals molecular details of an RNA regulator of replication. Nucleic Acids Res., 49, 2021
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6D3P
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![BU of 6d3p by Molmil](/molmil-images/mine/6d3p) | Crystal structure of an exoribonuclease-resistant RNA from Sweet clover necrotic mosaic virus (SCNMV) | Descriptor: | IRIDIUM HEXAMMINE ION, RNA (45-MER) | Authors: | Steckelberg, A.-L, Akiyama, B.M, Costantino, D.A, Sit, T.L, Nix, J.C, Kieft, J.S. | Deposit date: | 2018-04-16 | Release date: | 2018-06-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A folded viral noncoding RNA blocks host cell exoribonucleases through a conformationally dynamic RNA structure. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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8TJQ
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