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PDB: 17 件

1JPS
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Crystal structure of tissue factor in complex with humanized Fab D3h44
分子名称: immunoglobulin Fab D3H44, heavy chain, light chain, ...
著者Faelber, K, Kirchhofer, D, Presta, L, Kelley, R.F, Muller, Y.A.
登録日2001-08-03
公開日2002-02-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The 1.85 A resolution crystal structures of tissue factor in complex with humanized Fab D3h44 and of free humanized Fab D3h44: revisiting the solvation of antigen combining sites.
J.Mol.Biol., 313, 2001
1JPT
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Crystal Structure of Fab D3H44
分子名称: immunoglobulin Fab D3H44, heavy chain, immunoglobulin Fab D3h44, ...
著者Faelber, K, Kirchhofer, D, Presta, L, Kelley, R.F, Muller, Y.A.
登録日2001-08-03
公開日2002-02-03
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The 1.85 A resolution crystal structures of tissue factor in complex with humanized Fab D3h44 and of free humanized Fab D3h44: revisiting the solvation of antigen combining sites.
J.Mol.Biol., 313, 2001
3U30
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Crystal structure of a linear-specific Ubiquitin fab bound to linear ubiquitin
分子名称: Heavy chain Fab, Light chain Fab, linear di-ubiquitin
著者Matsumoto, M.L, Dong, K.C, Yu, C, Phu, L, Gao, X, Hannoush, R.N, Hymowitz, S.G, Kirkpatrick, D.S, Dixit, V.M, Kelley, R.F.
登録日2011-10-04
公開日2012-01-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.428 Å)
主引用文献Engineering and structural characterization of a linear polyubiquitin-specific antibody.
J.Mol.Biol., 418, 2012
1K6Q
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Crystal structure of antibody Fab fragment D3
分子名称: immunoglobulin Fab D3, heavy chain, light chain
著者Faelber, K, Kelley, R.F, Kirchhofer, D, Muller, Y.A.
登録日2001-10-17
公開日2002-04-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structure of murine Fab D3 at 2.4 A resolution in comparison with the humanised Fab D3h44 (1.85A) provides structural insight into the humanisation process of the D3 anti-tissue factor antibody
To be Published
1XU2
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The crystal structure of APRIL bound to BCMA
分子名称: NICKEL (II) ION, Tumor necrosis factor ligand superfamily member 13, Tumor necrosis factor receptor superfamily member 17
著者Hymowitz, S.G, Patel, D.R, Wallweber, H.J.A, Runyon, S, Yan, M, Yin, J, Shriver, S.K, Gordon, N.C, Pan, B, Skelton, N.J, Kelley, R.F, Starovasnik, M.A.
登録日2004-10-25
公開日2004-11-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structures of APRIL-receptor complexes: Like BCMA, TACI employs only a single cysteine-rich domain for high-affinity ligand binding
J.Biol.Chem., 280, 2005
4LMQ
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Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12
分子名称: Stromal cell-derived factor 1, hu30D8 Fab heavy chain, hu30D8 Fab light chain
著者Zhong, Z, Wang, J, Li, B, Xiang, H, Ultsch, M, Coons, M, Wong, T, Chiang, N.Y, Clark, S, Clark, R, Quintana, L, Gribling, P, Suto, E, Barck, K, Corpuz, R, Yao, J, Takkar, R, Lee, W.P, Damico-Beyer, L.A, Carano, R.D, Adams, C, Kelley, R.F, Wang, W, Ferrara, N.
登録日2013-07-10
公開日2013-08-14
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.773 Å)
主引用文献Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12.
Clin.Cancer Res., 19, 2013
1OSX
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Solution Structure of the Extracellular Domain of BLyS Receptor 3 (BR3)
分子名称: Tumor necrosis factor receptor superfamily member 13C
著者Gordon, N.C, Pan, B, Hymowitz, S.G, Yin, J.P, Kelley, R.F, Cochran, A.G, Yan, M, Dixit, V.M, Fairbrother, W.J, Starovasnik, M.A.
登録日2003-03-20
公開日2003-05-27
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献BAFF/BLyS receptor 3 comprises a minimal TNF receptor-like module that encodes a highly focused ligand-binding site
Biochemistry, 42, 2003
1OSG
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Complex between BAFF and a BR3 derived peptide presented in a beta-hairpin scaffold
分子名称: BR3 derived PEPTIDE, MAGNESIUM ION, Tumor necrosis factor ligand superfamily member 13B
著者Gordon, N.C, Pan, B, Hymowitz, S.G, Yin, J.P, Kelley, R.F, Cochran, A.G, Yan, M, Dixit, V.M, Fairbrother, W.J, Starovasnik, M.A.
登録日2003-03-19
公開日2003-05-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献BAFF/BLyS receptor 3 comprises a minimal TNF receptor-like module that encodes a highly focused ligand-binding site
Biochemistry, 42, 2003
1TPK
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CRYSTAL STRUCTURE OF THE KRINGLE-2 DOMAIN OF TISSUE PLASMINOGEN ACTIVATOR AT 2.4-ANGSTROMS RESOLUTION
分子名称: CHLORIDE ION, TISSUE PLASMINOGEN ACTIVATOR
著者De vos, A.M, Ultsch, M.H, Kelley, R.F, Padmanabhan, K, Tulinsky, A, Westbrook, M.L, Kossiakoff, A.A.
登録日1991-09-24
公開日1992-07-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the kringle 2 domain of tissue plasminogen activator at 2.4-A resolution.
Biochemistry, 31, 1992
1XUT
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Solution structure of TACI-CRD2
分子名称: Tumor necrosis factor receptor superfamily member 13B
著者Hymowitz, S.G, Patel, D.R, Wallweber, H.J, Runyon, S, Yan, M, Yin, J, Shriver, S.K, Gordon, N.C, Pan, B, Skelton, N.J, Kelley, R.F, Starovasnik, M.A.
登録日2004-10-26
公開日2004-11-09
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Structures of APRIL-receptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding.
J.Biol.Chem., 280, 2005
1XU1
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The crystal structure of APRIL bound to TACI
分子名称: NICKEL (II) ION, Tumor necrosis factor ligand superfamily member 13, Tumor necrosis factor receptor superfamily member 13B
著者Hymowitz, S.G, Patel, D.R, Wallweber, H.J.A, Runyon, S, Yan, M, Yin, J, Shriver, S.K, Gordon, N.C, Pan, B, Skelton, N.J, Kelley, R.F, Starovasnik, M.A.
登録日2004-10-25
公開日2004-11-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of APRIL-receptor complexes: Like BCMA, TACI employs only a single cysteine-rich domain for high-affinity ligand binding
J.Biol.Chem., 280, 2005
1DG6
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CRYSTAL STRUCTURE OF APO2L/TRAIL
分子名称: APO2L/TNF-RELATED APOPOTIS INDUCING LIGAND (TRAIL), CHLORIDE ION, ZINC ION
著者Hymowitz, S.G, O'ConnelL, M.P, Ultsch, M.H, de Vos, A.M, Kelley, R.F.
登録日1999-11-23
公開日2000-01-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL.
Biochemistry, 39, 2000
1D0G
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CRYSTAL STRUCTURE OF DEATH RECEPTOR 5 (DR5) BOUND TO APO2L/TRAIL
分子名称: APOPTOSIS-2 LIGAND, CHLORIDE ION, DEATH RECEPTOR-5, ...
著者Hymowitz, S.G, Christinger, H.W, Fuh, G, O'Connell, M.P, Kelley, R.F, Ashkenazi, A, de Vos, A.M.
登録日1999-09-09
公開日1999-10-22
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5.
Mol.Cell, 4, 1999
1F7M
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THE FIRST EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FVII, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: PROTEIN (Blood Coagulation Factor VII)
著者Kao, Y.-H, Lee, G.F, Wang, Y, Starovasnik, M.A, Kelley, R.F, Spellman, M.W, Lerner, L.
登録日1999-02-19
公開日1999-06-16
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII.
Biochemistry, 38, 1999
1F7E
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THE FIRST EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FVII, NMR, 20 STRUCTURES
分子名称: PROTEIN (Blood Coagulation Factor VII)
著者Kao, Y.-H, Lee, G.F, Wang, Y, Starovasnik, M.A, Kelley, R.F, Spellman, M.W, Lerner, L.
登録日1999-02-19
公開日1999-06-16
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII.
Biochemistry, 38, 1999
1FFM
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THE FIRST EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FVII (FUCOSYLATED AT SER-60), NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: PROTEIN (Blood Coagulation Factor VII), alpha-L-fucopyranose
著者Kao, Y.-H, Lee, G.F, Wang, Y, Starovasnik, M.A, Kelley, R.F, Spellman, M.W, Lerner, L.
登録日1999-02-19
公開日1999-06-16
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII.
Biochemistry, 38, 1999
1FF7
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THE FIRST EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FVII (FUCOSYLATED AT SER-60), NMR, 20 STRUCTURES
分子名称: PROTEIN (Blood Coagulation Factor VII), alpha-L-fucopyranose
著者Kao, Y.-H, Lee, G.F, Wang, Y, Starovasnik, M.A, Kelley, R.F, Spellman, M.W, Lerner, L.
登録日1999-02-19
公開日1999-06-16
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII.
Biochemistry, 38, 1999

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