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PDB: 4 件

8PM4
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BU of 8pm4 by Molmil
Cryo-EM structure of the Cas12m-crRNA-target DNA complex
分子名称: DNA oligoduplex, non-target strand, chain D, ...
著者Sasnauskas, G, Tamulaitiene, G, Karvelis, T, Bigelyte, G, Siksnys, V.
登録日2023-06-28
公開日2024-02-07
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Innate programmable DNA binding by CRISPR-Cas12m effectors enable efficient base editing.
Nucleic Acids Res., 52, 2024
8BF8
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BU of 8bf8 by Molmil
ISDra2 TnpB in complex with reRNA
分子名称: Deinococcus radiodurans R1 chromosome 1, RNA-guided DNA endonuclease TnpB
著者Sasnauskas, G, Tamulaitiene, G, Carabias, A, Siksnys, V, Montoya, G, Druteika, G, Silanskas, A, Venclovas, C, Karvelis, T, Kazlauskas, D.
登録日2022-10-24
公開日2023-04-12
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献TnpB structure reveals minimal functional core of Cas12 nuclease family.
Nature, 616, 2023
8EXA
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BU of 8exa by Molmil
ISDra2 TnpB in complex with reRNA and cognate DNA, conformation 1 (RuvC domain resolved)
分子名称: DNA (43-MER), RNA (150-MER), RNA-guided DNA endonuclease TnpB
著者Sasnauskas, G, Tamulaitiene, G, Carabias, A, Karvelis, T, Druteika, G, Silanskas, A, Montoya, G, Venclovas, C, Kazlauskas, D, Siksnys, V.
登録日2022-10-25
公開日2023-04-05
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献TnpB structure reveals minimal functional core of Cas12 nuclease family.
Nature, 616, 2023
8EX9
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BU of 8ex9 by Molmil
ISDra2 TnpB in complex with reRNA and cognate DNA, conformation 2 (RuvC domain unresolved)
分子名称: DNA (43-MER), RNA (150-MER), RNA-guided DNA endonuclease TnpB
著者Sasnauskas, G, Tamulaitiene, G, Carabias, A, Karvelis, T, Druteika, G, Silanskas, A, Montoya, G, Venclovas, C, Kazlauskas, D, Siksnys, V.
登録日2022-10-25
公開日2023-04-05
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.96 Å)
主引用文献TnpB structure reveals minimal functional core of Cas12 nuclease family.
Nature, 616, 2023

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件を2024-11-06に公開中

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