7L9E
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![BU of 7l9e by Molmil](/molmil-images/mine/7l9e) | Crystal structure of apo-alpha glucosidase | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Karade, S.S, Mariuzza, R.A. | Deposit date: | 2021-01-03 | Release date: | 2021-12-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum alpha-Glucosidases I and II with Antiviral Activity. J.Med.Chem., 64, 2021
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8EUR
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![BU of 8eur by Molmil](/molmil-images/mine/8eur) | Co-crystal structure of Chaetomium glucosidase with compound 26 | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-{[2-nitro-4-(triazan-1-yl)phenyl]amino}ethyl (2-{[(1S,2S,3R,4S,5S)-2,3,4,5-tetrahydroxy-5-(hydroxymethyl)cyclohexyl]amino}ethyl)carbamate, Chaetomium alpha glucosidase, ... | Authors: | Karade, S.S, Mariuzza, R.A. | Deposit date: | 2022-10-19 | Release date: | 2023-02-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Structure-Based Design of Potent Iminosugar Inhibitors of Endoplasmic Reticulum alpha-Glucosidase I with Anti-SARS-CoV-2 Activity. J.Med.Chem., 66, 2023
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8EUX
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![BU of 8eux by Molmil](/molmil-images/mine/8eux) | Co-crystal structure of Chaetomium glucosidase with compound 28 | Descriptor: | (2R,3R,4R,5S)-2-(hydroxymethyl)-1-{5-[4-(2-methoxyethyl)phenyl]pentyl}piperidine-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Chaetomium alpha glucosidase, ... | Authors: | Karade, S.S, Mariuzza, R.A. | Deposit date: | 2022-10-19 | Release date: | 2023-02-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-Based Design of Potent Iminosugar Inhibitors of Endoplasmic Reticulum alpha-Glucosidase I with Anti-SARS-CoV-2 Activity. J.Med.Chem., 66, 2023
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6ICR
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![BU of 6icr by Molmil](/molmil-images/mine/6icr) | LdCoroCC mutant- C482A | Descriptor: | 1,2-ETHANEDIOL, Coronin-like protein | Authors: | Karade, S.S, Srivastava, V.K, Ansari, A, Pratap, J.V. | Deposit date: | 2018-09-06 | Release date: | 2019-10-09 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Molecular and structural analysis of a mechanical transition of helices in the L. donovani coronin coiled-coil domain. Int.J.Biol.Macromol., 143, 2020
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6ADO
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![BU of 6ado by Molmil](/molmil-images/mine/6ado) | LdCoroCC mutant-I486A | Descriptor: | Coronin-like protein | Authors: | Karade, S.S, Ansari, A, Pratap, J.V. | Deposit date: | 2018-08-01 | Release date: | 2019-10-09 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.502 Å) | Cite: | Molecular and structural analysis of a mechanical transition of helices in the L. donovani coronin coiled-coil domain. Int.J.Biol.Macromol., 143, 2020
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3O3C
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![BU of 3o3c by Molmil](/molmil-images/mine/3o3c) | Glycogen synthase basal state UDP complex | Descriptor: | Glycogen [starch] synthase isoform 2, SULFATE ION, URIDINE-5'-DIPHOSPHATE | Authors: | Baskaran, S, Hurley, T.D. | Deposit date: | 2010-07-23 | Release date: | 2010-10-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.512 Å) | Cite: | Structural basis for glucose-6-phosphate activation of glycogen synthase. Proc.Natl.Acad.Sci.USA, 107, 2010
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3NCH
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3NAZ
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![BU of 3naz by Molmil](/molmil-images/mine/3naz) | Basal state form of Yeast Glycogen Synthase | Descriptor: | Glycogen [starch] synthase isoform 2, PEPTIDE, SULFATE ION | Authors: | Baskaran, S, Hurley, T.D. | Deposit date: | 2010-06-02 | Release date: | 2010-10-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for glucose-6-phosphate activation of glycogen synthase. Proc.Natl.Acad.Sci.USA, 107, 2010
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3NB0
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3RSZ
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![BU of 3rsz by Molmil](/molmil-images/mine/3rsz) | Maltodextran bound basal state conformation of yeast glycogen synthase isoform 2 | Descriptor: | Glycogen [starch] synthase isoform 2, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Baskaran, S, Hurley, T.D. | Deposit date: | 2011-05-02 | Release date: | 2011-08-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.009 Å) | Cite: | Multiple Glycogen-binding Sites in Eukaryotic Glycogen Synthase Are Required for High Catalytic Efficiency toward Glycogen. J.Biol.Chem., 286, 2011
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5SUK
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3RT1
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4EXV
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![BU of 4exv by Molmil](/molmil-images/mine/4exv) | Structure of Kluyveromyces lactis Hsv2p | Descriptor: | SULFATE ION, SVP1-like protein 2 | Authors: | Baskaran, S, Hurley, J.H. | Deposit date: | 2012-05-01 | Release date: | 2012-07-04 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Two-Site Recognition of Phosphatidylinositol 3-Phosphate by PROPPINs in Autophagy. Mol.Cell, 47, 2012
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1WB8
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![BU of 1wb8 by Molmil](/molmil-images/mine/1wb8) | Iron Superoxide Dismutase (FE-SOD) from the Hyperthermophile SULFOLOBUS SOLFATARICUS. 2.3 A Resolution Structure of Recombinant Protein with a Covalently Modified Tyrosine in the Active Site. | Descriptor: | FE (III) ION, SUPEROXIDE DISMUTASE [FE], phenylmethanesulfonic acid | Authors: | Ursby, T, Adinolfi, B.S, Al-Karadaghi, S, De Vendittis, E, Bocchini, V. | Deposit date: | 2004-10-31 | Release date: | 2004-11-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Iron Superoxide Dismutase from the Archaeon Sulfolobus Solfataricus: Analysis of Structure and Thermostability J.Mol.Biol., 286, 1999
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1EPL
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![BU of 1epl by Molmil](/molmil-images/mine/1epl) | A STRUCTURAL COMPARISON OF 21 INHIBITOR COMPLEXES OF THE ASPARTIC PROTEINASE FROM ENDOTHIA PARASITICA | Descriptor: | ENDOTHIAPEPSIN, PS1, PRO-LEU-GLU-PSA-ARG-LEU | Authors: | Al-Karadaghi, S, Cooper, J.B, Strop, P, Blundell, T.L. | Deposit date: | 1994-07-27 | Release date: | 1994-12-20 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A structural comparison of 21 inhibitor complexes of the aspartic proteinase from Endothia parasitica. Protein Sci., 3, 1994
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3M4Z
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![BU of 3m4z by Molmil](/molmil-images/mine/3m4z) | Crystal Structure of B. subtilis ferrochelatase with Cobalt bound at the active site | Descriptor: | CHLORIDE ION, COBALT (II) ION, Ferrochelatase, ... | Authors: | Soderberg, C.A.G, Hansson, M.D, Sreekanth, R, Al-Karadaghi, S, Hansson, M. | Deposit date: | 2010-03-12 | Release date: | 2010-11-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Bacterial ferrochelatase goes human: Tyr13 determines the apparent metal specificity of Bacillus subtilis ferrochelatase To be Published
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7DGX
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4UOE
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![BU of 4uoe by Molmil](/molmil-images/mine/4uoe) | Crystal Structure of Plasmodium Falciparum Spermidine Synthase in Complex with 5'-Deoxy-5'-Methylioadenosine and 4-Aminomethylaniline | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 4-(aminomethyl)aniline, 5'-DEOXY-5'-METHYLTHIOADENOSINE, ... | Authors: | Sprenger, J, Halander, J.C, Svensson, B, Al-Karadaghi, S, Person, L. | Deposit date: | 2014-06-03 | Release date: | 2014-10-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Three-Dimensional Structures of Plasmodium Falciparum Spermidine Synthase with Bound Inhibitors Suggest New Strategies for Drug Design. Acta Crystallogr.,Sect.D, 71, 2015
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4G2B
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7NCY
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![BU of 7ncy by Molmil](/molmil-images/mine/7ncy) | Dual specificity phosphatase from Sulfolobales Beppu filamentous virus 3 | Descriptor: | Dual specificity phosphatase, GLYCEROL, NICKEL (II) ION | Authors: | Welin, M, Akutsu, M, Hakansson, M, Al-Karadaghi, S, Jasilionis, A, Nordberg Karlsson, E. | Deposit date: | 2021-01-29 | Release date: | 2022-03-02 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Dual specificity phosphatase from Sulfolobales Beppu filamentous virus 3 To Be Published
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1FEU
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![BU of 1feu by Molmil](/molmil-images/mine/1feu) | CRYSTAL STRUCTURE OF RIBOSOMAL PROTEIN TL5, ONE OF THE CTC FAMILY PROTEINS, COMPLEXED WITH A FRAGMENT OF 5S RRNA. | Descriptor: | 19 NT FRAGMENT OF 5S RRNA, 21 NT FRAGMENT OF 5S RRNA, 50S RIBOSOMAL PROTEIN L25, ... | Authors: | Fedorov, R.V, Meshcheryakov, V.A, Gongadze, G.M, Fomenkova, N.P, Nevskaya, N.A, Selmer, M, Laurberg, M, Kristensen, O, Al-Karadaghi, S, Liljas, A, Garber, M.B, Nikonov, S.V. | Deposit date: | 2000-07-23 | Release date: | 2001-06-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of ribosomal protein TL5 complexed with RNA provides new insights into the CTC family of stress proteins. Acta Crystallogr.,Sect.D, 57, 2001
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1G8P
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![BU of 1g8p by Molmil](/molmil-images/mine/1g8p) | CRYSTAL STRUCTURE OF BCHI SUBUNIT OF MAGNESIUM CHELATASE | Descriptor: | MAGNESIUM-CHELATASE 38 KDA SUBUNIT | Authors: | Fodje, M.N, Hansson, A, Hansson, M, Olsen, J.G, Gough, S, Willows, R.D, Al-Karadaghi, S. | Deposit date: | 2000-11-20 | Release date: | 2001-08-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Interplay between an AAA module and an integrin I domain may regulate the function of magnesium chelatase. J.Mol.Biol., 311, 2001
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7R0T
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![BU of 7r0t by Molmil](/molmil-images/mine/7r0t) | Crystal structure of exonuclease ExnV1 | Descriptor: | CHLORIDE ION, Exonuclease ExnV1, MAGNESIUM ION, ... | Authors: | Welin, M, Svensson, A, Hakansson, M, Al-Karadaghi, S, Jasilionis, A, Linares-Pasten, J.A, Wang, L, Nordberg Karlsson, E, Ahlqvist, J. | Deposit date: | 2022-02-02 | Release date: | 2022-11-02 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.194 Å) | Cite: | Crystal structure of DNA polymerase I from Thermus phage G20c. Acta Crystallogr D Struct Biol, 78, 2022
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7R0K
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![BU of 7r0k by Molmil](/molmil-images/mine/7r0k) | Crystal structure of Polymerase I from phage G20c | Descriptor: | DNA polymerase I | Authors: | Welin, M, Svensson, A, Hakansson, M, Al-Karadaghi, S, Linares-Pasten, J.A, Jasilionis, A, Nordberg Karlsson, E, Ahlqvist, J. | Deposit date: | 2022-02-02 | Release date: | 2022-11-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.972 Å) | Cite: | Crystal structure of DNA polymerase I from Thermus phage G20c. Acta Crystallogr D Struct Biol, 78, 2022
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7R4W
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![BU of 7r4w by Molmil](/molmil-images/mine/7r4w) | Single stranded DNA binding protein SSB M5 from Fervidobacterium gondwanense | Descriptor: | ACETIC ACID, PHOSPHATE ION, Single-stranded DNA-binding protein | Authors: | Hakansson, M, Svensson, L.A, Werbowy, O, Al-Karadaghi, S, Kaczorowski, T, Kaczorowska, A.K, Dorawa, S. | Deposit date: | 2022-02-09 | Release date: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Molecular characterization of a single stranded DNA binding protein from Fervidobacterium gondwanense To Be Published
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