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PDB: 3 件

6C1O
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BU of 6c1o by Molmil
FGFR1 kinase domain complexed with FIIN-1
分子名称: Fibroblast growth factor receptor 1, N-(3-{[3-(2,6-dichloro-3,5-dimethoxyphenyl)-7-{[4-(diethylamino)butyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl}phenyl)prop-2-enamide, SULFATE ION
著者Kalyukina, M, Yosaatmadja, Y, Smaill, J.B, Squire, C.J.
登録日2018-01-05
公開日2019-01-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献A new class of FGFR1 inhibitors
To Be Published
6MZQ
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BU of 6mzq by Molmil
TAS-120 in reversible binding mode with FGFR1
分子名称: 1-[(3S)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-one, Fibroblast growth factor receptor 1
著者Kalyukina, M, Squire, C.J.
登録日2018-11-05
公開日2019-01-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献TAS-120 Cancer Target Binding: Defining Reactivity and Revealing the First Fibroblast Growth Factor Receptor 1 (FGFR1) Irreversible Structure.
ChemMedChem, 14, 2019
6MZW
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BU of 6mzw by Molmil
TAS-120 covalent complex with FGFR1
分子名称: 1-[(3S)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-one, Fibroblast growth factor receptor 1, SULFATE ION
著者Kalyukina, M, Squire, C.J.
登録日2018-11-05
公開日2019-01-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献TAS-120 Cancer Target Binding: Defining Reactivity and Revealing the First Fibroblast Growth Factor Receptor 1 (FGFR1) Irreversible Structure.
ChemMedChem, 14, 2019

222036

件を2024-07-03に公開中

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