6CJO
 
 | | Crystal Structure of Chalcone Isomerase from Medicago Sativa with the G95S mutation. | | 分子名称: | Chalcone--flavonone isomerase 1, SULFATE ION | | 著者 | Burke, J.R, La Clair, J.J, Philippe, R.N, Pabis, A, Jez, J.M, Cortina, G, Kaltenbach, M, Bowman, M.E, Woods, K.B, Nelson, A.T, Tawfik, D.S, Kamerlin, S.C.L, Noel, J.P. | | 登録日 | 2018-02-26 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Bifunctional Substrate Activation via an Arginine Residue Drives Catalysis in Chalcone Isomerases
Acs Catalysis, 2019
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6CJN
 | | Crystal Structure of Chalcone Isomerase from Medicago Sativa with the G95T mutation | | 分子名称: | Chalcone--flavonone isomerase 1, SULFATE ION | | 著者 | Burke, J.R, La Clair, J.J, Philippe, R.N, Pabis, A, Jez, J.M, Cortina, G, Kaltenbach, M, Bowman, M.E, Woods, K.B, Nelson, A.T, Tawfik, D.S, Kamerlin, S.C.L, Noel, J.P. | | 登録日 | 2018-02-26 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Bifunctional Substrate Activation via an Arginine Residue Drives Catalysis in Chalcone Isomerases
Acs Catalysis, 2019
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6MS8
 | | Crystal Structure of Chalcone Isomerase from Medicago Truncatula Complexed with (2S) Naringenin | | 分子名称: | Chalcone-flavonone isomerase family protein, NARINGENIN | | 著者 | Burke, J.R, La Clair, J.J, Philippe, R.N, Pabis, A, Jez, J.M, Cortina, G, Kaltenbach, M, Bowman, M.E, Woods, K.B, Nelson, A.T, Tawfik, D.S, Kamerlin, S.C.L, Noel, J.P. | | 登録日 | 2018-10-16 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Bifunctional Substrate Activation via an Arginine Residue Drives Catalysis in Chalcone Isomerases
Acs Catalysis, 2019
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4PCP
 | | Crystal structure of Phosphotriesterase variant R0 | | 分子名称: | CACODYLATE ION, Phosphotriesterase variant PTE-R0, ZINC ION | | 著者 | Campbell, E, Kaltenbach, M, Tokuriki, N, Jackson, C.J. | | 登録日 | 2014-04-16 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | The role of protein dynamics in the evolution of new enzyme function.
Nat. Chem. Biol., 12, 2016
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4PBF
 | | Phosphotriesterase variant Rev12 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase variant PTE-revR12, ... | | 著者 | Campbell, E, Kaltenbach, M, Tokuriki, N, Jackson, C.J. | | 登録日 | 2014-04-12 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The role of protein dynamics in the evolution of new enzyme function.
Nat. Chem. Biol., 12, 2016
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4PCN
 | | Phosphotriesterase variant R22 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Phosphotriesterase variant PTE-R22, ZINC ION | | 著者 | Jackson, C.J, Campbell, E, Kaltenbach, M, Tokuriki, N. | | 登録日 | 2014-04-16 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | The role of protein dynamics in the evolution of new enzyme function.
Nat. Chem. Biol., 12, 2016
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4PBE
 | | Phosphotriesterase Variant Rev6 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase variant PTE-revR6, ... | | 著者 | Campbell, E, Kaltenbach, M, Tokuriki, N, Jackson, C.J. | | 登録日 | 2014-04-12 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | The role of protein dynamics in the evolution of new enzyme function.
Nat. Chem. Biol., 12, 2016
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4XD4
 | | Phosphotriesterase variant E2b | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase variant PTE-R3, ... | | 著者 | Jackson, C.J, Campbell, E, Kaltenbach, M, Tokuriki, N. | | 登録日 | 2014-12-19 | | 公開日 | 2015-12-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The role of protein dynamics in the evolution of new enzyme function.
Nat.Chem.Biol., 12, 2016
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4XAG
 | | Cycles of destabilization and repair underlie the evolution of new enzyme function | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase variant PTE-R6, ... | | 著者 | Jackson, C.J, Campbell, E, Kaltenbach, M, Tokuriki, N. | | 登録日 | 2014-12-14 | | 公開日 | 2015-12-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The role of protein dynamics in the evolution of new enzyme function.
Nat.Chem.Biol., 12, 2016
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4XD3
 | | Phosphotriesterase variant E3 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase variant PTE-E1, ... | | 著者 | Jackson, C.J, Campbell, E, Kaltenbach, M, Tokuriki, N. | | 登録日 | 2014-12-19 | | 公開日 | 2015-12-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | The role of protein dynamics in the evolution of new enzyme function.
Nat.Chem.Biol., 12, 2016
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4XD6
 | | Phosphotriesterase Variant E2a | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase variant PTE-E2, ... | | 著者 | Jackson, C.J, Campbell, E, Kaltenbach, M, Tokuriki, N. | | 登録日 | 2014-12-19 | | 公開日 | 2015-12-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | The role of protein dynamics in the evolution of new enzyme function.
Nat.Chem.Biol., 12, 2016
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4XD5
 | | Phosphotriesterase variant R2 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase variant PTE-R2, ... | | 著者 | Campbell, E, Kaltenbach, M, Tokuriki, N, Jackson, C.J. | | 登録日 | 2014-12-19 | | 公開日 | 2015-12-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | The role of protein dynamics in the evolution of new enzyme function.
Nat.Chem.Biol., 12, 2016
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4XAY
 | | Cycles of destabilization and repair underlie evolutionary transitions in enzymes | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase variant PTE-R8, ... | | 著者 | Jackson, C.J, Campbell, E, Kaltenbach, M, Tokuriki, N. | | 登録日 | 2014-12-16 | | 公開日 | 2015-12-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | The role of protein dynamics in the evolution of new enzyme function.
Nat.Chem.Biol., 12, 2016
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4XAZ
 | | Cycles of destabilization and repair underlie evolutionary transitions in enzymes | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Phosphotriesterase variant PTE-R18, ZINC ION | | 著者 | Jackson, C.J, Campbell, E, Kaltenbach, M, Tokuriki, N. | | 登録日 | 2014-12-16 | | 公開日 | 2015-12-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | The role of protein dynamics in the evolution of new enzyme function.
Nat.Chem.Biol., 12, 2016
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4XAF
 | | Cycles of destabilization and repair underlie evolutionary transitions in enzymes | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase variant PTE-R1, ... | | 著者 | Jackson, C.J, Campbell, E, Kaltenbach, M, Tokuriki, N. | | 登録日 | 2014-12-14 | | 公開日 | 2015-12-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | The role of protein dynamics in the evolution of new enzyme function.
Nat.Chem.Biol., 12, 2016
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5WL8
 | | Crystal structure of chalcone isomerase engineered from ancestral inference (epR4) | | 分子名称: | Engineered Chalcone Isomerase epR4, FORMIC ACID | | 著者 | Burke, J.R, Kaltenbach, M, Tawfik, D.S, Noel, J.P. | | 登録日 | 2017-07-25 | | 公開日 | 2018-05-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Evolution of chalcone isomerase from a noncatalytic ancestor.
Nat. Chem. Biol., 14, 2018
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5WKR
 | | Crystal structure of chalcone isomerase engineered from ancestral inference complexed with naringenin (ancCC) | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Engineered Chalcone Isomerase ancCC, ... | | 著者 | Burke, J.R, Kaltenbach, M, Tawfik, D.S, Noel, J.P. | | 登録日 | 2017-07-25 | | 公開日 | 2018-05-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Evolution of chalcone isomerase from a noncatalytic ancestor.
Nat. Chem. Biol., 14, 2018
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5WL4
 | | Crystal structure of chalcone isomerase engineered from ancestral inference (ancR3) | | 分子名称: | Engineered Chalcone Isomerase ancR3, FORMIC ACID | | 著者 | Burke, J.R, Kaltenbach, M, Tawfik, D.S, Noel, J.P. | | 登録日 | 2017-07-25 | | 公開日 | 2018-05-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Evolution of chalcone isomerase from a noncatalytic ancestor.
Nat. Chem. Biol., 14, 2018
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5WL6
 | | Crystal structure of chalcone isomerase engineered from ancestral inference (AncR7) | | 分子名称: | CHLORIDE ION, Engineered Chalcone Isomerase AncR7 | | 著者 | Burke, J.R, Kaltenbach, M, Tawfik, D.S, Noel, J.P. | | 登録日 | 2017-07-25 | | 公開日 | 2018-05-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Evolution of chalcone isomerase from a noncatalytic ancestor.
Nat. Chem. Biol., 14, 2018
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5WL3
 | | Crystal structure of chalcone isomerase engineered from ancestral inference (ancR2) | | 分子名称: | CHLORIDE ION, Engineered Chalcone Isomerase ancR2 | | 著者 | Burke, J.R, Kaltenbach, M, Tawfik, D.S, Noel, J.P. | | 登録日 | 2017-07-25 | | 公開日 | 2018-05-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Evolution of chalcone isomerase from a noncatalytic ancestor.
Nat. Chem. Biol., 14, 2018
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5WKS
 | | Crystal structure of chalcone isomerase engineered from ancestral inference complexed with naringenin (ancR1) | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Engineered Chalcone Isomerase ancR1, FORMIC ACID, ... | | 著者 | Burke, J.R, Kaltenbach, M, Tawfik, D.S, Noel, J.P. | | 登録日 | 2017-07-25 | | 公開日 | 2018-05-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Evolution of chalcone isomerase from a noncatalytic ancestor.
Nat. Chem. Biol., 14, 2018
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5WL5
 | | Crystal structure of chalcone isomerase engineered from ancestral inference (ancR5) | | 分子名称: | CHLORIDE ION, Engineered Chalcone Isomerase ancR5, SULFATE ION | | 著者 | Burke, J.R, Kaltenbach, M, Tawfik, D.S, Noel, J.P. | | 登録日 | 2017-07-25 | | 公開日 | 2018-05-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.513 Å) | | 主引用文献 | Evolution of chalcone isomerase from a noncatalytic ancestor.
Nat. Chem. Biol., 14, 2018
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5WL7
 | | Crystal structure of chalcone isomerase engineered from ancestral inference (ancCHI*) | | 分子名称: | CHLORIDE ION, Engineered Chalcone Isomerase ancCHI* | | 著者 | Burke, J.R, Kaltenbach, M, Tawfik, D.S, Noel, J.P. | | 登録日 | 2017-07-25 | | 公開日 | 2018-05-09 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Evolution of chalcone isomerase from a noncatalytic ancestor.
Nat. Chem. Biol., 14, 2018
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