3SJX
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![BU of 3sjx by Molmil](/molmil-images/mine/3sjx) | X-ray structure of human glutamate carboxypeptidase II (the E424A inactive mutant) in complex with N-acetyl-aspartyl-methionine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Plechanovova, A, Byun, Y, Alquicer, G, Skultetyova, L, Mlcochova, P, Nemcova, A, Kim, H, Navratil, M, Mease, R, Lubkowski, J, Pomper, M, Konvalinka, J, Rulisek, L, Barinka, C. | Deposit date: | 2011-06-22 | Release date: | 2011-10-05 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Novel Substrate-Based Inhibitors of Human Glutamate Carboxypeptidase II with Enhanced Lipophilicity. J.Med.Chem., 54, 2011
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2R1N
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![BU of 2r1n by Molmil](/molmil-images/mine/2r1n) | OpdA from Agrobacterium radiobacter with bound slow substrate diethyl 4-methoxyphenyl phosphate (20h)- 1.7 A | Descriptor: | COBALT (II) ION, DIETHYL 4-METHOXYPHENYL PHOSPHATE, FE (II) ION, ... | Authors: | Ollis, D.L, Jackson, C.J, Foo, J.L, Kim, H.K, Carr, P.D, Liu, J.W, Salem, G. | Deposit date: | 2007-08-23 | Release date: | 2008-02-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | In crystallo capture of a Michaelis complex and product-binding modes of a bacterial phosphotriesterase J.Mol.Biol., 375, 2008
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2R1P
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![BU of 2r1p by Molmil](/molmil-images/mine/2r1p) | OpdA from Agrobacterium radiobacter with bound product diethyl thiophosphate from co-crystallisation with tetraethyl dithiopyrophosphate- 1.8 A | Descriptor: | 1,2-ETHANEDIOL, COBALT (II) ION, FE (II) ION, ... | Authors: | Ollis, D.L, Jackson, C.J, Foo, J.L, Kim, H.K, Carr, P.D, Liu, J.W, Salem, G. | Deposit date: | 2007-08-23 | Release date: | 2008-02-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | In crystallo capture of a Michaelis complex and product-binding modes of a bacterial phosphotriesterase J.Mol.Biol., 375, 2008
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2XJ3
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![BU of 2xj3 by Molmil](/molmil-images/mine/2xj3) | High resolution structure of the T55C mutant of CylR2. | Descriptor: | CYLR2 SYNONYM CYTOLYSIN REPRESSOR 2, GLYCEROL | Authors: | Gruene, T, Cho, M.K, Karyagina, I, Kim, H.Y, Grosse, C, Giller, K, Zweckstetter, M, Becker, S. | Deposit date: | 2010-07-02 | Release date: | 2011-02-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.23 Å) | Cite: | Integrated Analysis of the Conformation of a Protein-Linked Spin Label by Crystallography, Epr and NMR Spectroscopy. J.Biomol.NMR, 49, 2011
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1PVE
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![BU of 1pve by Molmil](/molmil-images/mine/1pve) | |
5GLC
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![BU of 5glc by Molmil](/molmil-images/mine/5glc) | Crystal structure of the class A beta-lactamase PenL-tTR11 containing 20 residues insertion in omega-loop | Descriptor: | Beta-lactamase | Authors: | Choi, J.M, Yi, H, Kim, H.S, Lee, S.H. | Deposit date: | 2016-07-10 | Release date: | 2017-02-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.601 Å) | Cite: | High adaptability of the omega loop underlies the substrate-spectrum-extension evolution of a class A beta-lactamase, PenL Sci Rep, 6, 2016
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5GLD
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![BU of 5gld by Molmil](/molmil-images/mine/5gld) | Crystal structure of the class A beta-lactamase PenL-tTR11 in complex with CBA | Descriptor: | Beta-lactamase, PINACOL[[2-AMINO-ALPHA-(1-CARBOXY-1-METHYLETHOXYIMINO)-4-THIAZOLEACETYL]AMINO]METHANEBORONATE | Authors: | Choi, J.M, Yi, H, Kim, H.S, Lee, S.H. | Deposit date: | 2016-07-10 | Release date: | 2017-02-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | High adaptability of the omega loop underlies the substrate-spectrum-extension evolution of a class A beta-lactamase, PenL Sci Rep, 6, 2016
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7ML3
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![BU of 7ml3 by Molmil](/molmil-images/mine/7ml3) | General transcription factor TFIIH (weak binding) | Descriptor: | BJ4_G0050160.mRNA.1.CDS.1, General transcription and DNA repair factor IIH, General transcription and DNA repair factor IIH helicase subunit XPB, ... | Authors: | Yang, C, Fujiwara, R, Kim, H.J, Gorbea Colon, J.J, Steimle, S, Garcia, B.A, Murakami, K. | Deposit date: | 2021-04-27 | Release date: | 2022-02-02 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (7.6 Å) | Cite: | Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II. Mol.Cell, 82, 2022
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2R1K
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![BU of 2r1k by Molmil](/molmil-images/mine/2r1k) | OpdA from Agrobacterium radiobacter with bound diethyl phosphate from crystal soaking with the compound- 1.9 A | Descriptor: | 1,2-ETHANEDIOL, COBALT (II) ION, DIETHYL HYDROGEN PHOSPHATE, ... | Authors: | Ollis, D.L, Jackson, C.J, Foo, J.L, Kim, H.K, Carr, P.D, Liu, J.W, Salem, G. | Deposit date: | 2007-08-23 | Release date: | 2008-02-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | In crystallo capture of a Michaelis complex and product-binding modes of a bacterial phosphotriesterase J.Mol.Biol., 375, 2008
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1UAK
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![BU of 1uak by Molmil](/molmil-images/mine/1uak) | Crystal structure of tRNA(m1G37)methyltransferase: Insight into tRNA recognition | Descriptor: | S-ADENOSYLMETHIONINE, tRNA (Guanine-N(1)-)-methyltransferase | Authors: | Ahn, H.J, Kim, H.-W, Yoon, H.-J, Lee, B.I, Suh, S.W, Yang, J.K. | Deposit date: | 2003-03-11 | Release date: | 2003-06-17 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structure of tRNA(m(1)G37)methyltransferase: insights into tRNA recognition EMBO J., 22, 2003
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1UAL
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![BU of 1ual by Molmil](/molmil-images/mine/1ual) | Crystal structure of tRNA(m1G37)methyltransferase: Insight into tRNA recognition | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, tRNA (Guanine-N(1)-)-methyltransferase | Authors: | Ahn, H.J, Kim, H.-W, Yoon, H.-J, Lee, B.I, Suh, S.W, Yang, J.K. | Deposit date: | 2003-03-11 | Release date: | 2003-06-17 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of tRNA(m(1)G37)methyltransferase: insights into tRNA recognition EMBO J., 22, 2003
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2K7W
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![BU of 2k7w by Molmil](/molmil-images/mine/2k7w) | BAX Activation is Initiated at a Novel Interaction Site | Descriptor: | Apoptosis regulator BAX, Bcl-2-like protein 11 | Authors: | Gavathiotis, E, Suzuki, M, Davis, M.L, Pitter, K, Bird, G.H, Katz, S.G, Tu, H.C, Kim, H, Cheng, E.H, Tjandra, N, Walensky, L.D. | Deposit date: | 2008-08-27 | Release date: | 2008-10-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | BAX activation is initiated at a novel interaction site. Nature, 455, 2008
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2KDC
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![BU of 2kdc by Molmil](/molmil-images/mine/2kdc) | NMR Solution Structure of E. coli diacylglycerol kinase (DAGK) in DPC micelles | Descriptor: | Diacylglycerol kinase | Authors: | Van Horn, W.D, Kim, H, Ellis, C.D, Hadziselimovic, A, Sulistijo, E.S, Karra, M.D, Tian, C, Sonnichsen, F.D, Sanders, C.R. | Deposit date: | 2009-01-06 | Release date: | 2009-07-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution nuclear magnetic resonance structure of membrane-integral diacylglycerol kinase Science, 324, 2009
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7KPW
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![BU of 7kpw by Molmil](/molmil-images/mine/7kpw) | Structure of the H-lobe of yeast CKM | Descriptor: | Mediator of RNA polymerase II transcription subunit 12 | Authors: | Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L. | Deposit date: | 2020-11-12 | Release date: | 2021-01-27 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module. Sci Adv, 7, 2021
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3FXI
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![BU of 3fxi by Molmil](/molmil-images/mine/3fxi) | Crystal structure of the human TLR4-human MD-2-E.coli LPS Ra complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-HYDROXY-TETRADECANOIC ACID, ... | Authors: | Park, B.S, Song, D.H, Kim, H.M, Lee, J.-O. | Deposit date: | 2009-01-21 | Release date: | 2009-03-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex Nature, 458, 2009
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2LYQ
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![BU of 2lyq by Molmil](/molmil-images/mine/2lyq) | NOE-based 3D structure of the monomeric intermediate of CylR2 at 262K (-11 Celsius degrees) | Descriptor: | CylR2 | Authors: | Jaremko, M, Jaremko, L, Kim, H, Cho, M, Schwieters, C.D, Giller, K, Becker, S, Zweckstetter, M. | Deposit date: | 2012-09-19 | Release date: | 2013-02-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Cold denaturation of a protein dimer monitored at atomic resolution. Nat.Chem.Biol., 9, 2013
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2LYP
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![BU of 2lyp by Molmil](/molmil-images/mine/2lyp) | NOE-based 3D structure of the monomer of CylR2 in equilibrium with predissociated homodimer at 266K (-7 Celsius degrees) | Descriptor: | CylR2 | Authors: | Jaremko, M, Jaremko, L, Kim, H, Cho, M, Schwieters, C.D, Giller, K, Becker, S, Zweckstetter, M. | Deposit date: | 2012-09-19 | Release date: | 2013-02-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Cold denaturation of a protein dimer monitored at atomic resolution. Nat.Chem.Biol., 9, 2013
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2LYJ
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![BU of 2lyj by Molmil](/molmil-images/mine/2lyj) | NOE-based 3D structure of the CylR2 homodimer at 298K | Descriptor: | CylR2 | Authors: | Jaremko, M, Jaremko, L, Kim, H, Cho, M, Giller, K, Becker, S, Zweckstetter, M, Schwieters, C.D. | Deposit date: | 2012-09-19 | Release date: | 2013-02-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Cold denaturation of a protein dimer monitored at atomic resolution. Nat.Chem.Biol., 9, 2013
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2LYK
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![BU of 2lyk by Molmil](/molmil-images/mine/2lyk) | NOE-based 3D structure of the CylR2 homodimer at 270K (-3 Celsius degrees) | Descriptor: | CylR2 | Authors: | Jaremko, M, Jaremko, L, Kim, H, Cho, M, Schwieters, C.D, Giller, K, Becker, S, Zweckstetter, M. | Deposit date: | 2012-09-19 | Release date: | 2013-02-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Cold denaturation of a protein dimer monitored at atomic resolution. Nat.Chem.Biol., 9, 2013
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3UYU
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![BU of 3uyu by Molmil](/molmil-images/mine/3uyu) | Structural basis for the antifreeze activity of an ice-binding protein (LeIBP) from Arctic yeast | Descriptor: | Antifreeze protein, GLYCEROL | Authors: | Lee, J.H, Park, A.K, Do, H, Park, K.S, Moh, S.H, Chi, Y.M, Kim, H.J. | Deposit date: | 2011-12-06 | Release date: | 2012-02-15 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Structural basis for the antifreeze activity of an ice-binding protein from an Arctic yeast. J.Biol.Chem., 2012
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2K21
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![BU of 2k21 by Molmil](/molmil-images/mine/2k21) | NMR structure of human KCNE1 in LMPG micelles at pH 6.0 and 40 degree C | Descriptor: | Potassium voltage-gated channel subfamily E member | Authors: | Kang, C, Tian, C, Sonnichsen, F.D, Smith, J.A, Meiler, J, George, A.L, Vanoye, C.G, Sanders, C.R, Kim, H. | Deposit date: | 2008-03-19 | Release date: | 2008-12-09 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of KCNE1 and implications for how it modulates the KCNQ1 potassium channel. Biochemistry, 47, 2008
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3UYV
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![BU of 3uyv by Molmil](/molmil-images/mine/3uyv) | Crystal structure of a glycosylated ice-binding protein (LeIBP) from Arctic yeast | Descriptor: | Antifreeze protein, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Lee, J.H, Park, A.K, Do, H, Park, K.S, Moh, S.H, Chi, Y.M, Kim, H.J. | Deposit date: | 2011-12-06 | Release date: | 2012-02-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Structural basis for the antifreeze activity of an ice-binding protein from an Arctic yeast. J.Biol.Chem., 2012
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3GN4
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![BU of 3gn4 by Molmil](/molmil-images/mine/3gn4) | Myosin lever arm | Descriptor: | CALCIUM ION, Calmodulin, MAGNESIUM ION, ... | Authors: | Mukherjea, M, Llinas, P, Kim, H, Travaglia, M, Safer, D, Zong, A.B, Menetrey, J, Franzini-Armstrong, C, Selvin, P.R, Houdusse, A, Sweeney, H.L. | Deposit date: | 2009-03-16 | Release date: | 2009-09-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Myosin VI dimerization triggers an unfolding of a three-helix bundle in order to extend its reach Mol.Cell, 35, 2009
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3QJM
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![BU of 3qjm by Molmil](/molmil-images/mine/3qjm) | Structural flexibility of Shank PDZ domain is important for its binding to different ligands | Descriptor: | Beta-PIX, SH3 and multiple ankyrin repeat domains protein 1 | Authors: | Lee, J.H, Park, H, Park, S.J, Kim, H.J, Eom, S.H. | Deposit date: | 2011-01-30 | Release date: | 2011-04-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.311 Å) | Cite: | The structural flexibility of the shank1 PDZ domain is important for its binding to different ligands Biochem.Biophys.Res.Commun., 407, 2011
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2LYL
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![BU of 2lyl by Molmil](/molmil-images/mine/2lyl) | NOE-based 3D structure of the predissociated homodimer of CylR2 in equilibrium with monomer at 266K (-7 Celsius degrees) | Descriptor: | CylR2 | Authors: | Jaremko, M, Jaremko, L, Kim, H, Cho, M, Schwieters, C.D, Giller, K, Becker, S, Zweckstetter, M. | Deposit date: | 2012-09-19 | Release date: | 2013-02-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Cold denaturation of a protein dimer monitored at atomic resolution. Nat.Chem.Biol., 9, 2013
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