3KI1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ki1 by Molmil](/molmil-images/mine/3ki1) | Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-F | Descriptor: | 2-{4-[3-(dimethylamino)propoxy]phenyl}-5,6-dihydroimidazo[4,5,1-jk][1,4]benzodiazepin-7(4H)-one, Cholix toxin | Authors: | Jorgensen, R, Edwards, P.R, Merrill, A.R. | Deposit date: | 2009-10-31 | Release date: | 2010-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae To be Published
|
|
2Q5T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2q5t by Molmil](/molmil-images/mine/2q5t) | Full-length Cholix toxin from Vibrio Cholerae | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Cholix toxin | Authors: | Jorgensen, R, Fieldhouse, R.J, Merrill, A.R. | Deposit date: | 2007-06-01 | Release date: | 2008-02-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Cholix Toxin, a Novel ADP-ribosylating Factor from Vibrio cholerae. J.Biol.Chem., 283, 2008
|
|
4X2C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4x2c by Molmil](/molmil-images/mine/4x2c) | Clostridium difficile Fic protein_0569 mutant S31A, E35A | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Fic family protein putative filamentation induced by cAMP protein, GLYCEROL, ... | Authors: | Jorgensen, R, Dedic, E. | Deposit date: | 2014-11-26 | Release date: | 2015-12-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of Clostridium difficile Fic_0569 S31A, E35A mutant at 1.8 Angstroms resolution To Be Published
|
|
4X2E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4x2e by Molmil](/molmil-images/mine/4x2e) | Clostridium difficile wild type Fic protein | Descriptor: | Fic family protein putative filamentation induced by cAMP protein | Authors: | Jorgensen, R, Dedic, E. | Deposit date: | 2014-11-26 | Release date: | 2015-12-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.104 Å) | Cite: | Structure of wild type Clostridium difficile Fic_0569 at 3.1 Angstroms resolution To Be Published
|
|
4X2D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4x2d by Molmil](/molmil-images/mine/4x2d) | |
1U2R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1u2r by Molmil](/molmil-images/mine/1u2r) | Crystal Structure of ADP-ribosylated Ribosomal Translocase from Saccharomyces cerevisiae | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Jorgensen, R, Yates, S.P, Nilsson, J, Prentice, G.A, Teal, D.J, Merrill, A.R, Andersen, G.R. | Deposit date: | 2004-07-20 | Release date: | 2004-09-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of ADP-ribosylated Ribosomal Translocase from Saccharomyces cerevisiae J.Biol.Chem., 279, 2004
|
|
3DOJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3doj by Molmil](/molmil-images/mine/3doj) | Structure of Glyoxylate reductase 1 from Arabidopsis (AtGLYR1) | Descriptor: | CHLORIDE ION, Dehydrogenase-like protein | Authors: | Jorgensen, R. | Deposit date: | 2008-07-04 | Release date: | 2009-07-07 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.101 Å) | Cite: | Cytosolic NADPH-dependent Glyoxylate Reductase from Arabidopsis: Crystal Structure and Kinetic Characterization of Active Site Mutants To be Published
|
|
2ZIT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zit by Molmil](/molmil-images/mine/2zit) | Structure of the eEF2-ExoA-NAD+ complex | Descriptor: | Elongation factor 2, Exotoxin A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Jorgensen, R, Merrill, A.R. | Deposit date: | 2008-02-24 | Release date: | 2008-06-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The nature and character of the transition state for the ADP-ribosyltransferase reaction. Embo Rep., 9, 2008
|
|
3B8H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3b8h by Molmil](/molmil-images/mine/3b8h) | Structure of the eEF2-ExoA(E546A)-NAD+ complex | Descriptor: | Elongation factor 2, Exotoxin A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Jorgensen, R, Merrill, A.R. | Deposit date: | 2007-11-01 | Release date: | 2008-06-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The nature and character of the transition state for the ADP-ribosyltransferase reaction. Embo Rep., 9, 2008
|
|
3B78
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3b78 by Molmil](/molmil-images/mine/3b78) | Structure of the eEF2-ExoA(R551H)-NAD+ complex | Descriptor: | Elongation factor 2, Exotoxin A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Jorgensen, R, Merrill, A.R. | Deposit date: | 2007-10-30 | Release date: | 2008-06-17 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The nature and character of the transition state for the ADP-ribosyltransferase reaction. Embo Rep., 9, 2008
|
|
3B82
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3b82 by Molmil](/molmil-images/mine/3b82) | Structure of the eEF2-ExoA(E546H)-NAD+ complex | Descriptor: | Elongation factor 2, Exotoxin A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Jorgensen, R, Merrill, A.R. | Deposit date: | 2007-10-31 | Release date: | 2008-06-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The nature and character of the transition state for the ADP-ribosyltransferase reaction. Embo Rep., 9, 2008
|
|
3KI0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ki0 by Molmil](/molmil-images/mine/3ki0) | Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-D | Descriptor: | 3-(morpholin-4-ylmethyl)-1,5-dihydro-6H-[1,2]diazepino[4,5,6-cd]indol-6-one, CHLORIDE ION, Cholix toxin | Authors: | Jorgensen, R, Edwards, P.R, Merrill, A.R. | Deposit date: | 2009-10-31 | Release date: | 2010-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.29 Å) | Cite: | Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae To be Published
|
|
3KI7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ki7 by Molmil](/molmil-images/mine/3ki7) | Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-I | Descriptor: | 2-{2-[4-(pyrrolidin-1-ylmethyl)phenyl]ethyl}-5,6-dihydroimidazo[4,5,1-jk][1,4]benzodiazepin-7(4H)-one, Cholix toxin | Authors: | Jorgensen, R, Edwards, P.R, Merrill, A.R. | Deposit date: | 2009-10-31 | Release date: | 2010-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae To be Published
|
|
3KI2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ki2 by Molmil](/molmil-images/mine/3ki2) | |
3KI4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ki4 by Molmil](/molmil-images/mine/3ki4) | Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-P | Descriptor: | (11bR)-3-oxo-1,2,3,11b-tetrahydrochromeno[4,3,2-de]isoquinoline-10-sulfonic acid, Cholix toxin, GLYCEROL | Authors: | Jorgensen, R, Edwards, P.R, Merrill, A.R. | Deposit date: | 2009-10-31 | Release date: | 2010-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae To be Published
|
|
3KI6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ki6 by Molmil](/molmil-images/mine/3ki6) | Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-L | Descriptor: | 8-fluoro-2-(3-piperidin-1-ylpropanoyl)-1,3,4,5-tetrahydrobenzo[c][1,6]naphthyridin-6(2H)-one, Cholix toxin | Authors: | Jorgensen, R, Edwards, P.R, Merrill, A.R. | Deposit date: | 2009-10-31 | Release date: | 2010-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae To be Published
|
|
3KI3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ki3 by Molmil](/molmil-images/mine/3ki3) | Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-H | Descriptor: | 2-[(dimethylamino)methyl]-5,6-dihydroimidazo[4,5,1-jk][1,4]benzodiazepin-7(4H)-one, Cholix toxin | Authors: | Jorgensen, R, Edwards, P.R, Merrill, A.R. | Deposit date: | 2009-10-31 | Release date: | 2010-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.27 Å) | Cite: | Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae To be Published
|
|
3KI5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ki5 by Molmil](/molmil-images/mine/3ki5) | |
3ZGG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3zgg by Molmil](/molmil-images/mine/3zgg) | Crystal structure of the Fucosylgalactoside alpha N- acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with NPE caged UDP-Gal (C222(1) space group) | Descriptor: | 1-(2-NITROPHENYL)ETHYL UDP-GALACTOSE, GLYCEROL, HISTO-BLOOD GROUP ABO SYSTEM TRANSFERASE, ... | Authors: | Jorgensen, R, Batot, G.O, Hindsgaul, O, Tanaka, H, Perez, S, Imberty, A, Breton, C, Royant, A, Palcic, M.M. | Deposit date: | 2012-12-17 | Release date: | 2014-01-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structures of a Human Blood Group Glycosyltransferase in Complex with a Photo-Activatable Udp-Gal Derivative Reveal Two Different Binding Conformations Acta Crystallogr.,Sect.F, 70, 2014
|
|
3ZGF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3zgf by Molmil](/molmil-images/mine/3zgf) | Crystal structure of the Fucosylgalactoside alpha N- acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with in complex with NPE caged UDP-Gal (P2(1)2(1)2(1) space group) | Descriptor: | 1-(2-NITROPHENYL)ETHYL UDP-GALACTOSE, HISTO-BLOOD GROUP ABO SYSTEM TRANSFERASE, MANGANESE (II) ION, ... | Authors: | Jorgensen, R, Batot, G.O, Hindsgaul, O, Tanaka, H, Perez, S, Imberty, A, Breton, C, Royant, A, Palcic, M.M. | Deposit date: | 2012-12-17 | Release date: | 2013-01-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.701 Å) | Cite: | Structures of a Human Blood Group Glycosyltransferase in Complex with a Photo-Activatable Udp-Gal Derivative Reveal Two Different Binding Conformations Acta Crystallogr.,Sect.F, 70, 2014
|
|
3U0Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3u0y by Molmil](/molmil-images/mine/3u0y) | Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with compound 382 and UDP | Descriptor: | 1-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine, GLYCEROL, Histo-blood group ABO system transferase, ... | Authors: | Palcic, M.M, Jorgensen, R. | Deposit date: | 2011-09-29 | Release date: | 2012-10-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A novel compound from a molecular fragment library screen inhibits glycosyltransferases by displacing the metal ion and interfering with substrate binding To be Published
|
|
4V4B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v4b by Molmil](/molmil-images/mine/4v4b) | Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models for RNA and protein components into a 11.7 A cryo-EM map. | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S11, ... | Authors: | Spahn, C.M, Gomez-Lorenzo, M.G, Grassucci, R.A, Jorgensen, R, Andersen, G.R, Beckmann, R, Penczek, P.A, Ballesta, J.P.G, Frank, J. | Deposit date: | 2004-01-06 | Release date: | 2014-07-09 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (11.7 Å) | Cite: | Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation. Embo J., 23, 2004
|
|
3Q9O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3q9o by Molmil](/molmil-images/mine/3q9o) | |
3NY6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ny6 by Molmil](/molmil-images/mine/3ny6) | Catalytic fragment of cholix toxin from vibrio cholerae in complex with inhibitor V30 | Descriptor: | 2-[(5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)sulfanyl]-N-(2-hydroxyethyl)acetamide, Cholix toxin, GLYCEROL, ... | Authors: | Merrill, A.R, Jorgensen, R. | Deposit date: | 2010-07-14 | Release date: | 2010-12-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Newly discovered and characterized antivirulence compounds inhibit bacterial mono-ADP-ribosyltransferase toxins. Antimicrob.Agents Chemother., 55, 2011
|
|
2Q6M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2q6m by Molmil](/molmil-images/mine/2q6m) | |