1U2R
 
 | | Crystal Structure of ADP-ribosylated Ribosomal Translocase from Saccharomyces cerevisiae | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Jorgensen, R, Yates, S.P, Nilsson, J, Prentice, G.A, Teal, D.J, Merrill, A.R, Andersen, G.R. | | 登録日 | 2004-07-20 | | 公開日 | 2004-09-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of ADP-ribosylated Ribosomal Translocase from Saccharomyces cerevisiae
J.Biol.Chem., 279, 2004
|
|
2Q5T
 | | Full-length Cholix toxin from Vibrio Cholerae | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Cholix toxin | | 著者 | Jorgensen, R, Fieldhouse, R.J, Merrill, A.R. | | 登録日 | 2007-06-01 | | 公開日 | 2008-02-12 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Cholix Toxin, a Novel ADP-ribosylating Factor from Vibrio cholerae.
J.Biol.Chem., 283, 2008
|
|
4X2C
 | | Clostridium difficile Fic protein_0569 mutant S31A, E35A | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Fic family protein putative filamentation induced by cAMP protein, GLYCEROL, ... | | 著者 | Jorgensen, R, Dedic, E. | | 登録日 | 2014-11-26 | | 公開日 | 2015-12-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of Clostridium difficile Fic_0569 S31A, E35A mutant at 1.8 Angstroms resolution
To Be Published
|
|
4X2E
 | |
4X2D
 | |
2ZIT
 | | Structure of the eEF2-ExoA-NAD+ complex | | 分子名称: | Elongation factor 2, Exotoxin A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Jorgensen, R, Merrill, A.R. | | 登録日 | 2008-02-24 | | 公開日 | 2008-06-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The nature and character of the transition state for the ADP-ribosyltransferase reaction.
Embo Rep., 9, 2008
|
|
3KI2
 | |
3KI4
 | | Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-P | | 分子名称: | (11bR)-3-oxo-1,2,3,11b-tetrahydrochromeno[4,3,2-de]isoquinoline-10-sulfonic acid, Cholix toxin, GLYCEROL | | 著者 | Jorgensen, R, Edwards, P.R, Merrill, A.R. | | 登録日 | 2009-10-31 | | 公開日 | 2010-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae
To be Published
|
|
3KI1
 | | Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-F | | 分子名称: | 2-{4-[3-(dimethylamino)propoxy]phenyl}-5,6-dihydroimidazo[4,5,1-jk][1,4]benzodiazepin-7(4H)-one, Cholix toxin | | 著者 | Jorgensen, R, Edwards, P.R, Merrill, A.R. | | 登録日 | 2009-10-31 | | 公開日 | 2010-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae
To be Published
|
|
3DOJ
 | |
3KI0
 | | Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-D | | 分子名称: | 3-(morpholin-4-ylmethyl)-1,5-dihydro-6H-[1,2]diazepino[4,5,6-cd]indol-6-one, CHLORIDE ION, Cholix toxin | | 著者 | Jorgensen, R, Edwards, P.R, Merrill, A.R. | | 登録日 | 2009-10-31 | | 公開日 | 2010-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | | 主引用文献 | Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae
To be Published
|
|
3KI7
 | | Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-I | | 分子名称: | 2-{2-[4-(pyrrolidin-1-ylmethyl)phenyl]ethyl}-5,6-dihydroimidazo[4,5,1-jk][1,4]benzodiazepin-7(4H)-one, Cholix toxin | | 著者 | Jorgensen, R, Edwards, P.R, Merrill, A.R. | | 登録日 | 2009-10-31 | | 公開日 | 2010-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | | 主引用文献 | Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae
To be Published
|
|
3B82
 | |
3KI3
 | | Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-H | | 分子名称: | 2-[(dimethylamino)methyl]-5,6-dihydroimidazo[4,5,1-jk][1,4]benzodiazepin-7(4H)-one, Cholix toxin | | 著者 | Jorgensen, R, Edwards, P.R, Merrill, A.R. | | 登録日 | 2009-10-31 | | 公開日 | 2010-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | | 主引用文献 | Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae
To be Published
|
|
3KI6
 | | Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-L | | 分子名称: | 8-fluoro-2-(3-piperidin-1-ylpropanoyl)-1,3,4,5-tetrahydrobenzo[c][1,6]naphthyridin-6(2H)-one, Cholix toxin | | 著者 | Jorgensen, R, Edwards, P.R, Merrill, A.R. | | 登録日 | 2009-10-31 | | 公開日 | 2010-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae
To be Published
|
|
3KI5
 | |
3B8H
 | |
3B78
 | |
3ZGG
 | | Crystal structure of the Fucosylgalactoside alpha N- acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with NPE caged UDP-Gal (C222(1) space group) | | 分子名称: | 1-(2-NITROPHENYL)ETHYL UDP-GALACTOSE, GLYCEROL, HISTO-BLOOD GROUP ABO SYSTEM TRANSFERASE, ... | | 著者 | Jorgensen, R, Batot, G.O, Hindsgaul, O, Tanaka, H, Perez, S, Imberty, A, Breton, C, Royant, A, Palcic, M.M. | | 登録日 | 2012-12-17 | | 公開日 | 2014-01-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structures of a Human Blood Group Glycosyltransferase in Complex with a Photo-Activatable Udp-Gal Derivative Reveal Two Different Binding Conformations
Acta Crystallogr.,Sect.F, 70, 2014
|
|
3ZGF
 | | Crystal structure of the Fucosylgalactoside alpha N- acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with in complex with NPE caged UDP-Gal (P2(1)2(1)2(1) space group) | | 分子名称: | 1-(2-NITROPHENYL)ETHYL UDP-GALACTOSE, HISTO-BLOOD GROUP ABO SYSTEM TRANSFERASE, MANGANESE (II) ION, ... | | 著者 | Jorgensen, R, Batot, G.O, Hindsgaul, O, Tanaka, H, Perez, S, Imberty, A, Breton, C, Royant, A, Palcic, M.M. | | 登録日 | 2012-12-17 | | 公開日 | 2013-01-23 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | | 主引用文献 | Structures of a Human Blood Group Glycosyltransferase in Complex with a Photo-Activatable Udp-Gal Derivative Reveal Two Different Binding Conformations
Acta Crystallogr.,Sect.F, 70, 2014
|
|
3NY6
 | | Catalytic fragment of cholix toxin from vibrio cholerae in complex with inhibitor V30 | | 分子名称: | 2-[(5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)sulfanyl]-N-(2-hydroxyethyl)acetamide, Cholix toxin, GLYCEROL, ... | | 著者 | Merrill, A.R, Jorgensen, R. | | 登録日 | 2010-07-14 | | 公開日 | 2010-12-29 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Newly discovered and characterized antivirulence compounds inhibit bacterial mono-ADP-ribosyltransferase toxins.
Antimicrob.Agents Chemother., 55, 2011
|
|
3Q9O
 | |
2Q6M
 | |
4V4B
 | | Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models for RNA and protein components into a 11.7 A cryo-EM map. | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S11, ... | | 著者 | Spahn, C.M, Gomez-Lorenzo, M.G, Grassucci, R.A, Jorgensen, R, Andersen, G.R, Beckmann, R, Penczek, P.A, Ballesta, J.P.G, Frank, J. | | 登録日 | 2004-01-06 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (11.7 Å) | | 主引用文献 | Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation.
Embo J., 23, 2004
|
|
3IOI
 | | Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with a novel UDP-Gal derived inhibitor (1GW) | | 分子名称: | 5-(2-FORMYLTHIEN-5-YL)-URIDINE-5'-DIPHOSPHATE-ALPHA-D-GALACTOSE, Histo-blood group ABO system transferase, MANGANESE (II) ION, ... | | 著者 | Pesnot, T, Jorgensen, R, Palcic, M.M, Wagner, G.K. | | 登録日 | 2009-08-14 | | 公開日 | 2010-04-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structural and mechanistic basis for a new mode of glycosyltransferase inhibition.
Nat.Chem.Biol., 6, 2010
|
|
