2J4J
| Crystal structure of uridylate kinase from Sulfolobus solfataricus in complex with UMP and AMPPCP to 2.1 Angstrom resolution | 分子名称: | COBALT (II) ION, MAGNESIUM ION, P1-(5'-ADENOSINE)P4-(5'-URIDINE)-BETA,GAMMA-METHYLENE TETRAPHOSPHATE, ... | 著者 | Jensen, K.S, Johansson, E, Jensen, K.F. | 登録日 | 2006-09-01 | 公開日 | 2007-02-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural and Enzymatic Investigation of the Sulfolobus Solfataricus Uridylate Kinase Shows Competitive Utp Inhibition and the Lack of GTP Stimulation Biochemistry, 46, 2007
|
|
2J4L
| |
2J4K
| Crystal structure of uridylate kinase from Sulfolobus solfataricus in complex with UMP to 2.2 Angstrom resolution | 分子名称: | CADMIUM ION, MAGNESIUM ION, URIDINE-5'-MONOPHOSPHATE, ... | 著者 | Jensen, K.S, Johansson, E, Jensen, K.F. | 登録日 | 2006-09-01 | 公開日 | 2007-02-27 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and Enzymatic Investigation of the Sulfolobus Solfataricus Uridylate Kinase Shows Competitive Utp Inhibition and the Lack of GTP Stimulation Biochemistry, 46, 2007
|
|
4B5G
| Substrate bound Neisseria AP endonuclease in absence of metal ions (crystal form 2) | 分子名称: | 5'-D(*CP*GP*AP*TP*GP*GP*GP*TP*AP*GP*CP)-3', 5'-D(*GP*CP*TP*AP*CP*(3DR)P*CP*AP*TP*CP*GP)-3', EXODEOXYRIBONUCLEASE | 著者 | Lu, D, Silhan, J, MacDonald, J.T, Carpenter, E.P, Jensen, K, Tang, C.M, Baldwin, G.S, Freemont, P.S. | 登録日 | 2012-08-03 | 公開日 | 2012-10-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis. Proc. Natl. Acad. Sci. U.S.A., 109, 2012
|
|
4B5I
| Product complex of Neisseria AP endonuclease in presence of metal ions | 分子名称: | 5'-D(*3DRP*CP*AP*TP*CP*GP)-3', 5'-D(*CP*GP*AP*TP*GP*GP*GP*TP*AP*GP*CP)-3', 5'-D(*GP*CP*TP*AP*CP)-3', ... | 著者 | Lu, D, Silhan, J, MacDonald, J.T, Carpenter, E.P, Jensen, K, Tang, C.M, Baldwin, G.S, Freemont, P.S. | 登録日 | 2012-08-03 | 公開日 | 2012-10-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.555 Å) | 主引用文献 | Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis. Proc. Natl. Acad. Sci. U.S.A., 109, 2012
|
|
4B5J
| Neisseria AP endonuclease bound to the substrate with an orphan Adenine base | 分子名称: | 5'-D(*CP*GP*AP*TP*GP*AP*GP*TP*AP*GP*CP)-3', 5'-D(*GP*CP*TP*AP*CP*(3DR)P*CP*AP*TP*CP*GP)-3', PUTATIVE EXODEOXYRIBONUCLEASE | 著者 | Lu, D, Silhan, J, MacDonald, J.T, Carpenter, E.P, Jensen, K, Tang, C.M, Baldwin, G.S, Freemont, P.S. | 登録日 | 2012-08-03 | 公開日 | 2012-10-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis. Proc. Natl. Acad. Sci. U.S.A., 109, 2012
|
|
4B5F
| Substrate bound Neisseria AP endonuclease in absence of metal ions (crystal form 1) | 分子名称: | 5'-D(*CP*GP*AP*TP*CP*GP*GP*TP*AP*GP*CP)-3', 5'-D(*GP*CP*TP*AP*CP*3DRP*GP*AP*TP*CP*GP)-3', PUTATIVE EXODEOXYRIBONUCLEASE | 著者 | Lu, D, Silhan, J, MacDonald, J.T, Carpenter, E.P, Jensen, K, Tang, C.M, Baldwin, G.S, Freemont, P.S. | 登録日 | 2012-08-03 | 公開日 | 2012-10-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.005 Å) | 主引用文献 | Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis. Proc. Natl. Acad. Sci. U.S.A., 109, 2012
|
|
1OVD
| THE K136E MUTANT OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDROGENASE A IN COMPLEX WITH OROTATE | 分子名称: | DIHYDROOROTATE DEHYDROGENASE A, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | 著者 | Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S. | 登録日 | 2003-03-26 | 公開日 | 2003-08-19 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function. J.Biol.Chem., 278, 2003
|
|
1XTT
| Sulfolobus solfataricus uracil phosphoribosyltransferase in complex with uridine 5'-monophosphate (UMP) | 分子名称: | ACETIC ACID, Probable uracil phosphoribosyltransferase, URIDINE-5'-MONOPHOSPHATE | 著者 | Arent, S, Harris, P, Jensen, K.F, Larsen, S. | 登録日 | 2004-10-24 | 公開日 | 2005-02-08 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Allosteric Regulation and Communication between Subunits in Uracil Phosphoribosyltransferase from Sulfolobus solfataricus(,) Biochemistry, 44, 2005
|
|
1XTU
| Sulfolobus solfataricus uracil phosphoribosyltransferase in complex with uridine 5'-monophosphate (UMP) and cytidine 5'-triphosphate (CTP) | 分子名称: | CYTIDINE-5'-TRIPHOSPHATE, Probable uracil phosphoribosyltransferase, URIDINE-5'-MONOPHOSPHATE | 著者 | Arent, S, Harris, P, Jensen, K.F, Larsen, S. | 登録日 | 2004-10-24 | 公開日 | 2005-02-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Allosteric Regulation and Communication between Subunits in Uracil Phosphoribosyltransferase from Sulfolobus solfataricus(,) Biochemistry, 44, 2005
|
|
1XTV
| Sulfolobus solfataricus uracil phosphoribosyltransferase with uridine 5'-monophosphate (UMP) bound to half of the subunits | 分子名称: | Probable uracil phosphoribosyltransferase, URIDINE-5'-MONOPHOSPHATE | 著者 | Arent, S, Harris, P, Jensen, K.F, Larsen, S. | 登録日 | 2004-10-24 | 公開日 | 2005-02-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Allosteric Regulation and Communication between Subunits in Uracil Phosphoribosyltransferase from Sulfolobus solfataricus(,) Biochemistry, 44, 2005
|
|
6T9D
| Crystal structure of a bispecific DutaFab in complex with human VEGF121 | 分子名称: | VP mat DutaFab VH chain, VP mat DutaFab VL chain, Vascular endothelial growth factor A | 著者 | Kimbung, R, Logan, D.T, Beckmann, R, Jensen, K, Speck, J, Fenn, S, Kettenberger, H. | 登録日 | 2019-10-28 | 公開日 | 2020-12-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.905 Å) | 主引用文献 | DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously. Nat Commun, 12, 2021
|
|
1JQV
| The K213E mutant of Lactococcus lactis Dihydroorotate dehydrogenase A | 分子名称: | ACETIC ACID, Dihydroorotate dehydrogenase A, FLAVIN MONONUCLEOTIDE, ... | 著者 | Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S. | 登録日 | 2001-08-09 | 公開日 | 2003-09-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function J.Biol.Chem., 278, 2003
|
|
1JRB
| The P56A mutant of Lactococcus lactis dihydroorotate dehydrogenase A | 分子名称: | FLAVIN MONONUCLEOTIDE, OROTIC ACID, dihydroorotate dehydrogenase A | 著者 | Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S. | 登録日 | 2001-08-13 | 公開日 | 2003-09-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function J.Biol.Chem., 278, 2003
|
|
1JUB
| The K136E mutant of lactococcus lactis dihydroorotate dehydrogenase A | 分子名称: | FLAVIN MONONUCLEOTIDE, GLYCEROL, MAGNESIUM ION, ... | 著者 | Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S. | 登録日 | 2001-08-24 | 公開日 | 2003-09-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function J.Biol.Chem., 278, 2003
|
|
1JQX
| The R57A mutant of Lactococcus lactis dihydroorotate dehydrogenase A | 分子名称: | FLAVIN MONONUCLEOTIDE, GLYCEROL, MAGNESIUM ION, ... | 著者 | Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S. | 登録日 | 2001-08-09 | 公開日 | 2003-09-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function J.Biol.Chem., 278, 2003
|
|
1JRC
| The N67A mutant of Lactococcus lactis dihydroorotate dehydrogenase A | 分子名称: | FLAVIN MONONUCLEOTIDE, OROTIC ACID, dihydroorotate dehydrogenase A | 著者 | Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S. | 登録日 | 2001-08-13 | 公開日 | 2003-09-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function J.Biol.Chem., 278, 2003
|
|
1JUE
| 1.8 A resolution structure of native lactococcus lactis dihydroorotate dehydrogenase A | 分子名称: | ACETIC ACID, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | 著者 | Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S. | 登録日 | 2001-08-24 | 公開日 | 2003-09-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function J.Biol.Chem., 278, 2003
|
|
1F76
| ESCHERICHIA COLI DIHYDROOROTATE DEHYDROGENASE | 分子名称: | Dihydroorotate dehydrogenase (quinone), FLAVIN MONONUCLEOTIDE, FORMIC ACID, ... | 著者 | Norager, S, Jensen, K.F, Bjornberg, O, Larsen, S. | 登録日 | 2000-06-26 | 公開日 | 2002-10-16 | 最終更新日 | 2014-03-12 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | E. coli Dihydroorotate Dehydrogenase Reveals Structural and Functional Distinction between different classes of
dihydroorotate dehydrogenases Structure, 10, 2002
|
|
4XCM
| Crystal structure of the putative NlpC/P60 D,L endopeptidase from T. thermophilus | 分子名称: | Cell wall-binding endopeptidase-related protein | 著者 | Wong, J, Midtgaard, S, Gysel, K, Thygesen, M.B, Sorensen, K.K, Jensen, K.J, Stougaard, J, Thirup, S, Blaise, M. | 登録日 | 2014-12-18 | 公開日 | 2015-01-14 | 最終更新日 | 2018-01-17 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | An intermolecular binding mechanism involving multiple LysM domains mediates carbohydrate recognition by an endopeptidase. Acta Crystallogr.,Sect.D, 71, 2015
|
|
4GQI
| Synthesis of novel MT3 receptor ligands via unusual Knoevenagel condensation | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, N-{(3R)-3-[2-(acetylamino)ethyl]-2-oxo-2,3-dihydro-1H-indol-5-yl}acetamide, ... | 著者 | Volkova, M.S, Jensen, K.C, Lozinskaya, N.A, Sosonyuk, S.E, Proskurnina, M.V, Mesecar, A.D, Zefirov, N.S. | 登録日 | 2012-08-23 | 公開日 | 2013-07-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.948 Å) | 主引用文献 | Synthesis of novel МТ3 receptor ligands via an unusual Knoevenagel condensation. Bioorg.Med.Chem.Lett., 22, 2012
|
|
4GR9
| Synthesis of novel MT3 receptor ligands via unusual Knoevenagel condensation | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, N-[(3R)-3-(cyanomethyl)-1-methyl-2-oxo-2,3-dihydro-1H-indol-5-yl]acetamide, ... | 著者 | Volkova, M.S, Jensen, K.C, Lozinskaya, N.A, Sosonyuk, S.E, Proskurnina, M.V, Mesecar, A.D, Zefirov, N.S. | 登録日 | 2012-08-24 | 公開日 | 2013-07-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.291 Å) | 主引用文献 | Synthesis of novel МТ3 receptor ligands via an unusual Knoevenagel condensation. Bioorg.Med.Chem.Lett., 22, 2012
|
|
5JOL
| Calcium-free EF-hand domain of L-plastin | 分子名称: | Plastin-2 | 著者 | Ishida, H, Jensen, K.V, Woodman, A.G, Hyndman, M.E, Vogel, H.J. | 登録日 | 2016-05-02 | 公開日 | 2017-04-19 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The Calcium-Dependent Switch Helix of L-Plastin Regulates Actin Bundling. Sci Rep, 7, 2017
|
|
5JOJ
| Calcium-loaded EF-hand domain of L-plastin | 分子名称: | CALCIUM ION, Plastin-2 | 著者 | Ishida, H, Jensen, K.V, Woodman, G.W, Hyndman, M.E, Vogel, H.J. | 登録日 | 2016-05-02 | 公開日 | 2017-04-19 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The Calcium-Dependent Switch Helix of L-Plastin Regulates Actin Bundling. Sci Rep, 7, 2017
|
|
6T9E
| Crystal structure of a bispecific DutaFab in complex with human PDGF | 分子名称: | DutaFab mat VH chain, DutaFab mat VL chain, Platelet-derived growth factor subunit B | 著者 | Kimbung, R, Logan, D.T, Beckmann, R, Jensen, K, Speck, J, Fenn, S, Kettenberger, H. | 登録日 | 2019-10-28 | 公開日 | 2020-12-16 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.989 Å) | 主引用文献 | DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously. Nat Commun, 12, 2021
|
|