4GQI
Synthesis of novel MT3 receptor ligands via unusual Knoevenagel condensation
Summary for 4GQI
Entry DOI | 10.2210/pdb4gqi/pdb |
Related | 4GR9 |
Descriptor | Ribosyldihydronicotinamide dehydrogenase [quinone], ZINC ION, GLYCEROL, ... (6 entities in total) |
Functional Keywords | oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P16083 |
Total number of polymer chains | 2 |
Total formula weight | 54043.29 |
Authors | Volkova, M.S.,Jensen, K.C.,Lozinskaya, N.A.,Sosonyuk, S.E.,Proskurnina, M.V.,Mesecar, A.D.,Zefirov, N.S. (deposition date: 2012-08-23, release date: 2013-07-10, Last modification date: 2024-02-28) |
Primary citation | Volkova, M.S.,Jensen, K.C.,Lozinskaya, N.A.,Sosonyuk, S.E.,Proskurnina, M.V.,Mesecar, A.D.,Zefirov, N.S. Synthesis of novel МТ3 receptor ligands via an unusual Knoevenagel condensation. Bioorg.Med.Chem.Lett., 22:7578-7581, 2012 Cited by PubMed: 23131339DOI: 10.1016/j.bmcl.2012.10.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.948 Å) |
Structure validation
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