6G4F
 
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6G4B
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6G4D
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6G4E
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1FXH
 | | MUTANT OF PENICILLIN ACYLASE IMPAIRED IN CATALYSIS WITH PHENYLACETIC ACID IN THE ACTIVE SITE | | 分子名称: | 2-PHENYLACETIC ACID, CALCIUM ION, PENICILLIN ACYLASE | | 著者 | Alkema, W.B, Hensgens, C.M, Kroezinga, E.H, de Vries, E, Floris, R, van der Laan, J.M, Dijkstra, B.W, Janssen, D.B. | | 登録日 | 2000-09-26 | | 公開日 | 2001-03-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Characterization of the beta-lactam binding site of penicillin acylase of Escherichia coli by structural and site-directed mutagenesis studies.
Protein Eng., 13, 2000
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1FXV
 | | PENICILLIN ACYLASE MUTANT IMPAIRED IN CATALYSIS WITH PENICILLIN G IN THE ACTIVE SITE | | 分子名称: | CALCIUM ION, PENICILLIN ACYLASE, PENICILLIN G | | 著者 | Alkema, W.B, Hensgens, C.M, Kroezinga, E.H, de Vries, E, Floris, R, van der Laan, J.M, Dijkstra, B.W, Janssen, D.B. | | 登録日 | 2000-09-27 | | 公開日 | 2001-03-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Characterization of the beta-lactam binding site of penicillin acylase of Escherichia coli by structural and site-directed mutagenesis studies.
Protein Eng., 13, 2000
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2YKV
 | | Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase | | 分子名称: | 1,2-ETHANEDIOL, 4'-DEOXY-4'-ACETYLYAMINO-PYRIDOXAL-5'-PHOSPHATE, BETA-TRANSAMINASE | | 著者 | Wybenga, G.G, Crismaru, C.G, Janssen, D.B, Dijkstra, B.W. | | 登録日 | 2011-05-30 | | 公開日 | 2012-05-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase.
J.Biol.Chem., 287, 2012
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2YKU
 | | Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase | | 分子名称: | 1,2-ETHANEDIOL, BETA-TRANSAMINASE, GLYCEROL, ... | | 著者 | Wybenga, G.G, Crismaru, C.G, Janssen, D.B, Dijkstra, B.W. | | 登録日 | 2011-05-30 | | 公開日 | 2012-05-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase.
J.Biol.Chem., 287, 2012
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2YKX
 | | Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase | | 分子名称: | 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, BETA-TRANSAMINASE, ... | | 著者 | Wybenga, G.G, Crismaru, C.G, Janssen, D.B, Dijkstra, B.W. | | 登録日 | 2011-05-30 | | 公開日 | 2012-05-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase.
J.Biol.Chem., 287, 2012
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2YKY
 | | Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase | | 分子名称: | (3S)-3-amino-3-phenylpropanoic acid, 1,2-ETHANEDIOL, BENZENE, ... | | 著者 | Wybenga, G.G, Crismaru, C.G, Janssen, D.B, Dijkstra, B.W. | | 登録日 | 2011-05-30 | | 公開日 | 2012-05-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase.
J.Biol.Chem., 287, 2012
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2YII
 | | Manipulating the regioselectivity of phenylalanine aminomutase: new insights into the reaction mechanism of MIO-dependent enzymes from structure-guided directed evolution | | 分子名称: | BETA-MERCAPTOETHANOL, FORMIC ACID, GLYCEROL, ... | | 著者 | Wu, B, Szymanski, W, Wybenga, G.G, Heberling, M.M, Bartsch, S, Wildeman, S, Poelarends, G.J, Feringa, B.L, Dijkstra, B.W, Janssen, D.B. | | 登録日 | 2011-05-13 | | 公開日 | 2011-11-09 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Mechanism-Inspired Engineering of Phenylalanine Aminomutase for Enhanced Beta-Regioselective Asymmetric Amination of Cinnamates.
Angew.Chem.Int.Ed.Engl., 51, 2012
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1PX0
 | | Crystal structure of the haloalcohol dehalogenase HheC complexed with the haloalcohol mimic (R)-1-para-nitro-phenyl-2-azido-ethanol | | 分子名称: | (R)-1-PARA-NITRO-PHENYL-2-AZIDO-ETHANOL, halohydrin dehalogenase | | 著者 | de Jong, R.M, Tiesinga, J.J.W, Rozeboom, H.J, Kalk, K.H, Tang, L, Janssen, D.B, Dijkstra, B.W. | | 登録日 | 2003-07-02 | | 公開日 | 2003-10-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure and Mechanism of a Bacterial Haloalcohol Dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site
EMBO J., 22, 2003
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1NX9
 | | Acetobacter turbidans alpha-amino acid ester hydrolase S205A mutant complexed with ampicillin | | 分子名称: | (2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, GLYCEROL, alpha-amino acid ester hydrolase | | 著者 | Barends, T.R.M, Polderman-Tijmes, J.J, Jekel, P.A, Janssen, D.B, Dijkstra, B.W. | | 登録日 | 2003-02-10 | | 公開日 | 2004-03-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Acetobacter turbidans {alpha}-Amino Acid Ester Hydrolase: HOW A SINGLE MUTATION IMPROVES AN ANTIBIOTIC-PRODUCING ENZYME.
J.Biol.Chem., 281, 2006
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1PWX
 | | Crystal structure of the haloalcohol dehalogenase HheC complexed with bromide | | 分子名称: | BROMIDE ION, halohydrin dehalogenase | | 著者 | de Jong, R.M, Tiesinga, J.J.W, Rozeboom, H.J, Kalk, K.H, Tang, L, Janssen, D.B, Dijkstra, B.W. | | 登録日 | 2003-07-02 | | 公開日 | 2003-10-07 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure and Mechanism of a Bacterial Haloalcohol Dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site
EMBO J., 22, 2003
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1PWZ
 | | Crystal structure of the haloalcohol dehalogenase HheC complexed with (R)-styrene oxide and chloride | | 分子名称: | CHLORIDE ION, R-STYRENE OXIDE, halohydrin dehalogenase | | 著者 | de Jong, R.M, Tiesinga, J.J.W, Rozeboom, H.J, Kalk, K.H, Tang, L, Janssen, D.B, Dijkstra, B.W. | | 登録日 | 2003-07-02 | | 公開日 | 2003-10-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure and Mechanism of a Bacterial Haloalcohol Dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site
EMBO J., 22, 2003
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4C6G
 | | Structural Investigations into the Stereochemistry and Activity of a Phenylalanine-2,3-Aminomutase from Taxus chinensis | | 分子名称: | PHENYLALANINE AMMONIA-LYASE | | 著者 | Wybenga, G.G, Szymanski, W, Wu, B, Feringa, B.L, Janssen, D.B, Dijkstra, B.W. | | 登録日 | 2013-09-18 | | 公開日 | 2014-05-07 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Investigations Into the Stereochemistry and Activity of a Phenylalanine-2,3-Aminomutase from Taxus Chinensis.
Biochemistry, 53, 2014
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4C5U
 | | Structural Investigations into the Stereochemistry and Activity of a Phenylalanine-2,3-Aminomutase from Taxus chinensis | | 分子名称: | PHENYLALANINE AMMONIA-LYASE | | 著者 | Wybenga, G.G, Szymanski, W, Wu, B, Feringa, B.L, Janssen, D.B, Dijkstra, B.W. | | 登録日 | 2013-09-16 | | 公開日 | 2014-05-07 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Structural Investigations Into the Stereochemistry and Activity of a Phenylalanine-2,3-Aminomutase from Taxus Chinensis.
Biochemistry, 53, 2014
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4CQ5
 | | Structural Investigations into the Stereochemistry and Activity of a Phenylalanine-2,3-Aminomutase from Taxus chinensis | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, PHENYLALANINE AMINOMUTASE, ... | | 著者 | Wybenga, G.G, Szymanski, W, Wu, B, Feringa, B.L, Janssen, D.B, Dijkstra, B.W. | | 登録日 | 2014-02-11 | | 公開日 | 2014-05-07 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Investigations Into the Stereochemistry and Activity of a Phenylalanine-2,3-Aminomutase from Taxus Chinensis.
Biochemistry, 53, 2014
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4BAA
 | | Redesign of a Phenylalanine Aminomutase into a beta-Phenylalanine Ammonia Lyase | | 分子名称: | PHENYLALANINE AMMONIA-LYASE | | 著者 | Bartsch, S, Wybenga, G.G, Jansen, M, Heberling, M.M, Wu, B, Dijkstra, B.W, Janssen, D.B. | | 登録日 | 2012-09-12 | | 公開日 | 2013-01-16 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Redesign of a Phenylalanine Aminomutase Into a Phenylalanine Ammonia Lyase
To be Published
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4AO4
 | | Structural Determinants of the beta-Selectivity of a Bacterial Aminotransferase | | 分子名称: | (3R)-3-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]-5-METHYLHEXANOIC ACID, 1,2-ETHANEDIOL, Beta-transaminase | | 著者 | Wybenga, G.G, Crismaru, C.G, Janssen, D.B, Dijkstra, B.W. | | 登録日 | 2012-03-23 | | 公開日 | 2012-06-06 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural determinants of the beta-selectivity of a bacterial aminotransferase.
J. Biol. Chem., 287, 2012
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6T8F
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6TB0
 | | Crystal structure of thermostable omega transaminase 4-fold mutant from Pseudomonas jessenii | | 分子名称: | Aspartate aminotransferase family protein, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Capra, N, Rozeboom, H.J, Thunnissen, A.M.W.H, Janssen, D.B. | | 登録日 | 2019-10-31 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Robust omega-Transaminases by Computational Stabilization of the Subunit Interface.
Acs Catalysis, 10, 2020
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6TB1
 | | Crystal structure of thermostable omega transaminase 6-fold mutant from Pseudomonas jessenii | | 分子名称: | Aspartate aminotransferase family protein, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Capra, N, Rozeboom, H.J, Thunnissen, A.M.W.H, Janssen, D.B. | | 登録日 | 2019-10-31 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Robust omega-Transaminases by Computational Stabilization of the Subunit Interface.
Acs Catalysis, 10, 2020
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4BAB
 | | Redesign of a Phenylalanine Aminomutase into a beta-Phenylalanine Ammonia Lyase | | 分子名称: | PHENYLALANINE AMINOMUTASE | | 著者 | Bartsch, S, Wybenga, G.G, Jansen, M, Heberling, M.M, Wu, B, Dijkstra, B.W, Janssen, D.B. | | 登録日 | 2012-09-12 | | 公開日 | 2013-01-16 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | Redesign of a Phenylalanine Aminomutase Into a Phenylalanine Ammonia Lyase
To be Published
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6TOZ
 | | Crystal structure of Bacillus paralicheniformis alpha-amylase in complex with acarbose | | 分子名称: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ACETIC ACID, Amylase, ... | | 著者 | Rozeboom, H.J, Janssen, D.B. | | 登録日 | 2019-12-12 | | 公開日 | 2020-10-14 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Characterization of the starch surface binding site on Bacillus paralicheniformis alpha-amylase.
Int.J.Biol.Macromol., 165, 2020
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