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PDB: 64 件
3ZO0
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BU of 3zo0 by Molmil
Mouse IgG2a in complex with mouse TRIM21 PRYSPRY
分子名称: E3 UBIQUITIN-PROTEIN LIGASE TRIM21, IG GAMMA-2A CHAIN C REGION, A ALLELE, ...
著者James, L.C.
登録日2013-02-19
公開日2013-05-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Trim21 is an Igg Receptor that is Structurally, Thermodynamically, and Kinetically Conserved.
Proc.Natl.Acad.Sci.USA, 105, 2008
4V1P
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BU of 4v1p by Molmil
BTN3 Structure
分子名称: BUTYROPHILIN SUBFAMILY 3 MEMBER A1
著者James, L.C.
登録日2014-09-30
公開日2015-07-22
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Activation of Human Gammadelta T Cells by Cytosolic Interactions of Btn3A1 with Soluble Phosphoantigens and the Cytoskeletal Adaptor Periplakin.
J.Immunol., 194, 2015
6H09
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BU of 6h09 by Molmil
HIV capsid hexamer with IP6 ligand
分子名称: Gag polyprotein, INOSITOL HEXAKISPHOSPHATE
著者James, L.C.
登録日2018-07-06
公開日2018-08-15
最終更新日2020-10-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献IP6 is an HIV pocket factor that prevents capsid collapse and promotes DNA synthesis.
Elife, 7, 2018
6ES8
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BU of 6es8 by Molmil
HIV capsid hexamer with IP6 ligand
分子名称: Gag protein, INOSITOL HEXAKISPHOSPHATE
著者James, L.C.
登録日2017-10-19
公開日2018-08-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献IP6 is an HIV pocket factor that prevents capsid collapse and promotes DNA synthesis.
Elife, 7, 2018
6ERN
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BU of 6ern by Molmil
HIV Hexamer with ligand
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Gag polyprotein
著者James, L.C.
登録日2017-10-18
公開日2018-11-07
最終更新日2020-04-01
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献HIV hexamer
To Be Published
6ERM
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BU of 6erm by Molmil
HIV Hexamer with ligand
分子名称: 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-TRIPHOSPHATE, Gag polyprotein
著者James, L.C.
登録日2017-10-18
公開日2018-11-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献HIV hexamer
To Be Published
5OLM
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BU of 5olm by Molmil
TRIM21
分子名称: E3 ubiquitin-protein ligase TRIM21, ZINC ION
著者James, L.C.
登録日2017-07-28
公開日2018-04-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21.
Elife, 7, 2018
6R8C
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BU of 6r8c by Molmil
HIV capsid hexamer with IP5 ligand
分子名称: Gag polyprotein, MYO-INOSITOL-(1,3,4,5,6)-PENTAKISPHOSPHATE
著者James, L.C.
登録日2019-04-01
公開日2020-05-06
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献HIV hexamer
to be published
6R6Q
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BU of 6r6q by Molmil
HIV capsid hexamer with IP5 ligand
分子名称: Gag polyprotein
著者James, L.C.
登録日2019-03-27
公開日2020-05-06
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献HIV hexamer
to be published
8A58
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BU of 8a58 by Molmil
X-ray structure of TRIM21 RING E3 ligase in complex with E2 enzyme Ube2W
分子名称: E3 ubiquitin-protein ligase TRIM21, Ubiquitin-conjugating enzyme E2 W, ZINC ION
著者James, L.C, Kiss, L.
登録日2022-06-14
公開日2023-04-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates.
Nat Commun, 14, 2023
7OVX
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BU of 7ovx by Molmil
E3 RING ligase binding domain
分子名称: E3 ubiquitin-protein ligase TRIM7, Peptide G
著者James, L.C.
登録日2021-06-15
公開日2022-06-22
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献E3 ligase targeting domain
To Be Published
7OW2
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BU of 7ow2 by Molmil
E3 RING ligase binding domain with peptide
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase RNF187 peptide, E3 ubiquitin-protein ligase TRIM7, ...
著者James, L.C.
登録日2021-06-16
公開日2022-07-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献E3 ligase targeting domain
To Be Published
1CE1
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BU of 1ce1 by Molmil
1.9A STRUCTURE OF THE THERAPEUTIC ANTIBODY CAMPATH-1H FAB IN COMPLEX WITH A SYNTHETIC PEPTIDE ANTIGEN
分子名称: PROTEIN (CAMPATH-1H:HEAVY CHAIN), PROTEIN (CAMPATH-1H:LIGHT CHAIN), PROTEIN (PEPTIDE ANTIGEN)
著者James, L.C, Hale, G, Waldmann, H, Bloomer, A.C.
登録日1999-03-12
公開日1999-06-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献1.9 A structure of the therapeutic antibody CAMPATH-1H fab in complex with a synthetic peptide antigen.
J.Mol.Biol., 289, 1999
2BJM
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BU of 2bjm by Molmil
SPE7:Anthrone Complex
分子名称: ANTHRONE, IGE SPE7 HEAVY CHAIN, IGE SPE7 LIGHT CHAIN
著者James, L.C, Tawfik, D.S.
登録日2005-02-04
公開日2005-08-18
最終更新日2013-10-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure and Kinetics of a Transient Antibody Binding Intermediate Reveal a Kinetic Discrimination Mechanism in Antigen Recognition
Proc.Natl.Acad.Sci.USA, 102, 2005
2BX5
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BU of 2bx5 by Molmil
Is FR1 the antibody's Achillies heel
分子名称: VD9 VKI LIGHT-CHAIN
著者James, L.C.
登録日2005-07-22
公開日2006-11-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Beta-Edge Interactions in a Pentadecameric Human Antibody Vkappa Domain.
J.Mol.Biol., 367, 2007
2IWG
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BU of 2iwg by Molmil
COMPLEX BETWEEN THE PRYSPRY DOMAIN OF TRIM21 AND IGG FC
分子名称: 52 KDA RO PROTEIN, IG GAMMA-1 CHAIN C, alpha-L-fucopyranose, ...
著者James, L.C, Keeble, A.H, Rhodes, D.A, Trowsdale, J.
登録日2006-06-30
公開日2007-03-27
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural Basis for Pryspry-Mediated Tripartite Motif (Trim) Protein Function.
Proc.Natl.Acad.Sci.USA, 104, 2007
1OAZ
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BU of 1oaz by Molmil
IgE Fv SPE7 complexed with a recombinant thioredoxin
分子名称: IMMUNOGLOBULIN E, THIOREDOXIN 1
著者James, L.C, Roversi, P, Tawfik, D.
登録日2003-01-21
公開日2004-01-15
最終更新日2013-10-30
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Antibody Multispecificity Mediated by Conformational Diversity
Science, 299, 2003
1OAX
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BU of 1oax by Molmil
Fv Structure of the IgE SPE-7 in complex with acenaphthenequinone
分子名称: ACENAPHTHENEQUINONE, IMMUNOGLOBULIN E
著者James, L.C, Roversi, P, Tawfik, D.
登録日2003-01-21
公開日2004-01-15
最終更新日2013-10-30
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Antibody Multispecificity Mediated by Conformational Diversity
Science, 299, 2003
1OAR
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BU of 1oar by Molmil
Fv IgE SPE-7 in complex with Alizarin Red
分子名称: 1,2-ETHANEDIOL, ALIZARIN RED, CACODYLATE ION, ...
著者James, L.C, Roversi, P, Tawfik, D.
登録日2003-01-21
公開日2004-01-15
最終更新日2013-10-30
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Antibody Multispecificity Mediated by Conformational Diversity
Science, 299, 2003
1OAU
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BU of 1oau by Molmil
Fv Structure of the IgE SPE-7 in complex with DNP-Ser (immunising hapten)
分子名称: 2,4-DINITROPHENOL, IMIDAZOLE, IMMUNOGLOBULIN E, ...
著者James, L.C, Roversi, P, Tawfik, D.
登録日2003-01-21
公開日2004-01-15
最終更新日2013-10-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Antibody Multispecificity Mediated by Conformational Diversity
Science, 299, 2003
1OAY
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BU of 1oay by Molmil
Antibody multispecificity mediated by conformational diversity
分子名称: Furazolidone, IMMUNOGLOBULIN E
著者James, L.C, Roversi, P, Tawfik, D.
登録日2003-01-21
公開日2004-01-15
最終更新日2013-10-30
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Antibody Multispecificity Mediated by Conformational Diversity
Science, 299, 2003
1OAQ
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BU of 1oaq by Molmil
Free conformation Ab1 of the IgE SPE-7
分子名称: HEAVY CHAIN, LIGHT CHAIN
著者James, L.C, Roversi, P, Tawfik, D.
登録日2003-01-21
公開日2004-01-15
最終更新日2013-10-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Antibody Multispecificity Mediated by Conformational Diversity
Science, 299, 2003
1OCW
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BU of 1ocw by Molmil
Free conformation Ab2 of the IgE SPE-7
分子名称: IMMUNOGLOBULIN E
著者James, L.C, Roversi, P, Tawfik, D.
登録日2003-02-11
公開日2004-02-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Antibody Multispecificity Mediated by Conformational Diversity
Science, 299, 2003
4U0F
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BU of 4u0f by Molmil
Hexameric HIV-1 CA in Complex with BI-2
分子名称: (4S)-4-(4-hydroxyphenyl)-3-phenyl-4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-one, 1,2-ETHANEDIOL, Capsid protein p24
著者Price, A.J, Jacques, D.A, James, L.C.
登録日2014-07-11
公開日2014-11-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly.
Plos Pathog., 10, 2014
4U0D
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BU of 4u0d by Molmil
Hexameric HIV-1 CA in complex with Nup153 peptide, P212121 crystal form
分子名称: CHLORIDE ION, Gag polyprotein, Nuclear pore complex protein Nup153
著者Price, A.J, Jacques, D.A, James, L.C.
登録日2014-07-11
公開日2014-11-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly.
Plos Pathog., 10, 2014

 

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