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PDB: 30 件
1HVU
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HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE COMPLEXED WITH A 33-BASE NUCLEOTIDE RNA PSEUDOKNOT
分子名称: PROTEIN (HIV-1 REVERSE TRANSCRIPTASE), RNA (33 NUCLEOTIDE RNA PSEUDOKNOT)
著者Jaeger, J, Restle, T, Steitz, T.A.
登録日1998-06-30
公開日1999-01-13
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (4.75 Å)
主引用文献The structure of HIV-1 reverse transcriptase complexed with an RNA pseudoknot inhibitor.
EMBO J., 17, 1998
4RY6
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C-terminal mutant (W550A) of HCV/J4 RNA polymerase
分子名称: HCV J4 RNA polymerase (NS5B)
著者Jaeger, J, Cherry, A, Dennis, C.
登録日2014-12-13
公開日2014-12-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Hydrophobic and Charged Residues in the C-Terminal Arm of Hepatitis C Virus RNA-Dependent RNA Polymerase Regulate Initiation and Elongation.
J.Virol., 89, 2015
4RY4
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C-terminal mutant (Y448F) of HCV/J4 RNA polymerase
分子名称: HCV J4 RNA polymerase (NS5B)
著者Jaeger, J, Cherry, A, Dennis, C.
登録日2014-12-13
公開日2014-12-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Hydrophobic and Charged Residues in the C-Terminal Arm of Hepatitis C Virus RNA-Dependent RNA Polymerase Regulate Initiation and Elongation.
J.Virol., 89, 2015
4RY7
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C-terminal mutant (D559E) of HCV/J4 RNA polymerase
分子名称: HCV J4 RNA polymerase (NS5B)
著者Jaeger, J, Cherry, A, Dennis, C.
登録日2014-12-13
公開日2014-12-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Hydrophobic and Charged Residues in the C-Terminal Arm of Hepatitis C Virus RNA-Dependent RNA Polymerase Regulate Initiation and Elongation.
J.Virol., 89, 2015
4RY5
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C-terminal mutant (W550N) of HCV/J4 RNA polymerase
分子名称: HCV J4 RNA polymerase (NS5B), MANGANESE (II) ION, URIDINE 5'-TRIPHOSPHATE
著者Jaeger, J, Cherry, A, Dennis, C.
登録日2014-12-13
公開日2014-12-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Hydrophobic and Charged Residues in the C-Terminal Arm of Hepatitis C Virus RNA-Dependent RNA Polymerase Regulate Initiation and Elongation.
J.Virol., 89, 2015
1ASM
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CRYSTAL STRUCTURES OF ESCHERICHIA COLI ASPARTATE AMINOTRANSFERASE IN TWO CONFORMATIONS: COMPARISON OF AN UNLIGANDED OPEN AND TWO LIGANDED CLOSED FORMS
分子名称: ASPARTATE AMINOTRANSFERASE, MALEIC ACID, PYRIDOXAL-5'-PHOSPHATE
著者Jaeger, J, Jansonius, J.N.
登録日1993-09-16
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structures of Escherichia coli aspartate aminotransferase in two conformations. Comparison of an unliganded open and two liganded closed forms.
J.Mol.Biol., 239, 1994
1ASN
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CRYSTAL STRUCTURES OF ESCHERICHIA COLI ASPARTATE AMINOTRANSFERASE IN TWO CONFORMATIONS: COMPARISON OF AN UNLIGANDED OPEN AND TWO LIGANDED CLOSED FORMS
分子名称: ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION
著者Jaeger, J, Jansonius, J.N.
登録日1993-09-16
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of Escherichia coli aspartate aminotransferase in two conformations. Comparison of an unliganded open and two liganded closed forms.
J.Mol.Biol., 239, 1994
1ASL
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CRYSTAL STRUCTURES OF ESCHERICHIA COLI ASPARTATE AMINOTRANSFERASE IN TWO CONFORMATIONS: COMPARISON OF AN UNLIGANDED OPEN AND TWO LIGANDED CLOSED FORMS
分子名称: 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID, ASPARTATE AMINOTRANSFERASE
著者Jaeger, J, Jansonius, J.N.
登録日1993-09-16
公開日1994-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of Escherichia coli aspartate aminotransferase in two conformations. Comparison of an unliganded open and two liganded closed forms.
J.Mol.Biol., 239, 1994
1AIA
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STRUCTURAL BASIS FOR THE CATALYTIC ACTIVITY OF ASPARTATE AMINOTRANSFERASE K258H LACKING THE PYRIDOXAL-5'-PHOSPHATE BINDING LYSINE RESIDUE
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ASPARTATE AMINOTRANSFERASE
著者Jaeger, J, Jansonius, J.N.
登録日1994-05-10
公開日1994-10-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for the catalytic activity of aspartate aminotransferase K258H lacking the pyridoxal 5'-phosphate-binding lysine residue.
Biochemistry, 34, 1995
1AIC
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STRUCTURAL BASIS FOR THE CATALYTIC ACTIVITY OF ASPARTATE AMINOTRANSFERASE K258H LACKING THE PYRIDOXAL-5'-PHOSPHATE BINDING LYSINE RESIDUE
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ASPARTATE AMINOTRANSFERASE, SULFATE ION
著者Jaeger, J, Jansonius, J.N.
登録日1994-05-10
公開日1994-10-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the catalytic activity of aspartate aminotransferase K258H lacking the pyridoxal 5'-phosphate-binding lysine residue.
Biochemistry, 34, 1995
1AIB
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STRUCTURAL BASIS FOR THE CATALYTIC ACTIVITY OF ASPARTATE AMINOTRANSFERASE K258H LACKING THE PYRIDOXAL-5'-PHOSPHATE BINDING LYSINE RESIDUE
分子名称: 2-OXOGLUTARIC ACID, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ASPARTATE AMINOTRANSFERASE
著者Jaeger, J, Jansonius, J.N.
登録日1994-05-10
公開日1994-10-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for the catalytic activity of aspartate aminotransferase K258H lacking the pyridoxal 5'-phosphate-binding lysine residue.
Biochemistry, 34, 1995
1NB4
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HC-J4 RNA polymerase apo-form
分子名称: polyprotein
著者Jaeger, J, O'Farrell, D.J, Trowbridge, R, Rowlands, D.J.
登録日2002-12-02
公開日2003-03-25
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Substrate complexes of hepatitis C virus RNA polymerase (HC-J4): structural evidence for nucleotide import and de-novo initiation.
J.Mol.Biol., 326, 2003
3HVT
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BU of 3hvt by Molmil
STRUCTURAL BASIS OF ASYMMETRY IN THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE HETERODIMER
分子名称: 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P51), HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66)
著者Steitz, T.A, Smerdon, S.J, Jaeger, J, Wang, J, Kohlstaedt, L.A, Chirino, A.J, Friedman, J.M, Rice, P.A.
登録日1994-07-25
公開日1994-10-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1.
Proc.Natl.Acad.Sci.Usa, 91, 1994
1JN3
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BU of 1jn3 by Molmil
FIDELITY PROPERTIES AND STRUCTURE OF M282L MUTATOR MUTANT OF DNA POLYMERASE: SUBTLE STRUCTURAL CHANGES INFLUENCE THE MECHANISM OF NUCLEOTIDE DISCRIMINATION
分子名称: DNA POLYMERASE BETA
著者Conn, D.A, Sweasy, J.B, Jaeger, J.
登録日2001-07-22
公開日2001-08-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献A DNA polymerase beta mutator mutant with reduced nucleotide discrimination and increased protein stability
Biochemistry, 40, 2001
6SY4
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TetR in complex with the TetR-binding RNA-aptamer K1
分子名称: TetR-binding aptamer K1 (43-MER), Tetracycline repressor protein class B from transposon Tn10
著者Grau, F.C, Muller, Y.A, Suess, B, Groher, F, Jaeger, J.
登録日2019-09-27
公開日2020-02-05
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.695 Å)
主引用文献The complex formed between a synthetic RNA aptamer and the transcription repressor TetR is a structural and functional twin of the operator DNA-TetR regulator complex.
Nucleic Acids Res., 48, 2020
6SY6
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TetR in complex with the TetR-binding RNA-aptamer K2
分子名称: RNA (36-MER), Tetracycline repressor protein class B from transposon Tn10
著者Grau, F.C, Muller, Y.A, Suess, B, Groher, F, Jaeger, J.
登録日2019-09-27
公開日2020-02-05
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The complex formed between a synthetic RNA aptamer and the transcription repressor TetR is a structural and functional twin of the operator DNA-TetR regulator complex.
Nucleic Acids Res., 48, 2020
3TB8
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Crystal structure of full-length myristoylated HIV-1 Nef
分子名称: Protein Nef
著者Dennis, C.A, Harris, M, Jaeger, J.
登録日2011-08-05
公開日2012-10-03
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.71 Å)
主引用文献Crystal structure of full-length myristoylated HIV-1 Nef
To be Published
1DYU
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BU of 1dyu by Molmil
The active site base controls cofactor reactivity in Escherichia coli amine oxidase: X-ray crystallographic studies with mutational variants.
分子名称: CALCIUM ION, COPPER (II) ION, COPPER AMINE OXIDASE
著者Murray, J.M, Wilmot, C.M, Saysell, C.G, Jaeger, J, Knowles, P.F, Phillips, S.E.V, McPherson, M.J.
登録日2000-02-08
公開日2000-02-29
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献The Active Site Base Controls Cofactor Reactivity in Escherichia Coli Amine Oxidase : X-Ray Crystallographicstudies with Mutational Variants
Biochemistry, 38, 1999
3V7J
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Co-crystal structure of Wild Type Rat polymerase beta: Enzyme-DNA binary complex
分子名称: CHLORIDE ION, DNA (5'-D(P*AP*TP*GP*TP*GP*AP*GP*T)-3'), DNA (5'-D(P*CP*AP*AP*AP*CP*TP*CP*AP*CP*AP*TP*A)-3'), ...
著者Rangarajan, S, Jaeger, J.
登録日2011-12-21
公開日2013-01-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystallographic studies of K72E mutant DNA polymerase explain loss of lyase function and reveal changes in the overall conformational state of the polymerase domain
To be Published
3V7K
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Co-crystal structure of K72E variant of rat polymerase beta: Enzyme-DNA binary complex
分子名称: DNA (5'-D(P*AP*TP*GP*TP*GP*AP*GP*T)-3'), DNA (5'-D(P*CP*AP*AP*AP*CP*TP*CP*AP*CP*AP*A)-3'), DNA polymerase beta, ...
著者Rangarajan, S, Jaeger, J.
登録日2011-12-21
公開日2013-01-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.271 Å)
主引用文献Crystallographic studies of K72E mutant DNA polymerase explain loss of lyase function and reveal changes in the overall conformational state of the polymerase domain
To be Published
3V7L
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Apo Structure of Rat DNA polymerase beta K72E variant
分子名称: CHLORIDE ION, DNA polymerase beta, SODIUM ION, ...
著者Rangarajan, S, Jaeger, J.
登録日2011-12-21
公開日2013-01-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Crystallographic studies of K72E mutant DNA polymerase explain loss of lyase function and reveal changes in the overall conformational state of the polymerase domain
To be Published
3V72
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Crystal Structure of Rat DNA polymerase beta Mutator E295K: Enzyme-dsDNA
分子名称: CHLORIDE ION, DNA 5'-D(P*AP*AP*AP*CP*TP*CP*AP*CP*AP*T)-3', DNA 5'-D(P*AP*TP*GP*TP*GP*AP*GP*T)-3', ...
著者Gridley, C.L, Jaeger, J.
登録日2011-12-20
公開日2012-07-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Unfavorable Electrostatic and Steric Interactions in DNA Polymerase beta E295K Mutant Interfere with the Enzyme s Pathway
J.Am.Chem.Soc., 134, 2012
3UXO
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Crystal Structure of Rat DNA Polymerase Beta Mutator I260Q Apoenzyme
分子名称: DNA polymerase beta
著者Gridley, C.L, Jaeger, J.
登録日2011-12-05
公開日2012-12-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Changes in the Hydrophobic Hinge Region Adversely Affect the Activity and Fidelity of the I260Q Mutator DNA Polymerase beta.
Biochemistry, 52, 2013
3UXP
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Co-crystal Structure of Rat DNA polymerase beta Mutator I260Q: Enzyme-DNA-ddTTP
分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA 5'-D(P*AP*CP*TP*CP*AP*CP*AP*TP*A)-3', DNA 5'-D(P*AP*TP*GP*TP*GP*AP*G)-3', ...
著者Gridley, C.L, Jaeger, J.
登録日2011-12-05
公開日2012-12-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.723 Å)
主引用文献Structural Changes in the Hydrophobic Hinge Region Adversely Affect the Activity and Fidelity of the I260Q Mutator DNA Polymerase beta.
Biochemistry, 52, 2013
3UXN
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Crystal Structure of Rat DNA Polymerase Beta, Wild Type Apoenzyme
分子名称: DNA polymerase beta
著者Gridley, C.L, Firbank, S, Jaeger, J.
登録日2011-12-05
公開日2012-12-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Changes in the Hydrophobic Hinge Region Adversely Affect the Activity and Fidelity of the I260Q Mutator DNA Polymerase beta.
Biochemistry, 52, 2013

 

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