3ZZ6
 
 | | Crystal structure of 3C protease of coxsackievirus B3 complexed with Michael receptor inhibitor 75 | | 分子名称: | ETHYL (4R)-4-({N-[(BENZYLOXY)CARBONYL]-L-PHENYLALANYL}AMINO)-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTANOATE, POLYPROTEIN 3BCD | | 著者 | Tan, J, Anand, K, Mesters, J.R, Hilgenfeld, R. | | 登録日 | 2011-08-31 | | 公開日 | 2012-09-19 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Peptidic Ab-Nonsaturated Ethyl Esters as Inhibitors of the 3C Protease of Coxsackie Virus B3: Crystal Structures, Antiviral Activities, and Resistance Mutations
To be Published
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3ZD8
 | | Potassium bound structure of E. coli ExoIX in P1 | | 分子名称: | POTASSIUM ION, PROTEIN XNI | | 著者 | Anstey-Gilbert, C.S, Hemsworth, G.R, Flemming, C.S, Hodskinson, M.R.G, Zhang, J, Sedelnikova, S.E, Stillman, T.J, Sayers, J.R, Artymiuk, P.J. | | 登録日 | 2012-11-26 | | 公開日 | 2013-07-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases
Nucleic Acids Res., 41, 2013
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4A82
 | | Fitted model of staphylococcus aureus sav1866 model ABC transporter in the human cystic fibrosis transmembrane conductance regulator volume map EMD-1966. | | 分子名称: | CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | | 著者 | Rosenberg, M.F, ORyan, L.P, Hughes, G, Zhao, Z, Aleksandrov, L.A, Riordan, J.R, Ford, R.C. | | 登録日 | 2011-11-18 | | 公開日 | 2012-01-11 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (9 Å) | | 主引用文献 | The Cystic Fibrosis Transmembrane Conductance Regulator (Cftr):3D Structure and Localisation of a Channel Gate.
J.Biol.Chem., 286, 2011
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1PAA
 | | STRUCTURE OF A HISTIDINE-X4-HISTIDINE ZINC FINGER DOMAIN: INSIGHTS INTO ADR1-UAS1 PROTEIN-DNA RECOGNITION | | 分子名称: | YEAST TRANSCRIPTION FACTOR ADR1, ZINC ION | | 著者 | Bernstein, B.E, Hoffman, R.C, Horvath, S.J, Herriott, J.R, Klevit, R.E. | | 登録日 | 1994-07-15 | | 公開日 | 1994-10-15 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of a histidine-X4-histidine zinc finger domain: insights into ADR1-UAS1 protein-DNA recognition.
Biochemistry, 33, 1994
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1OXA
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2KRJ
 | | High-Resolution Solid-State NMR Structure of a 17.6 kDa Protein | | 分子名称: | COBALT (II) ION, Macrophage metalloelastase | | 著者 | Bertini, I, Bhaumik, A, De Pa pe, G, Griffin, R.G, Lelli, M, Lewandowski, J.R, Luchinat, C. | | 登録日 | 2009-12-18 | | 公開日 | 2010-02-23 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | High-resolution solid-state NMR structure of a 17.6 kDa protein.
J.Am.Chem.Soc., 132, 2010
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6DQY
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2KYE
 | | Solution structure of the pseudouridine modified P6.1 hairpin of human telomerase RNA | | 分子名称: | RNA (5'-R(*GP*AP*GP*AP*GP*(PSU)P*(PSU)P*GP*GP*GP*CP*(PSU)P*CP*(PSU)P*C)-3') | | 著者 | Kim, N.-K, Theimer, C.A, Mitchell, J.R, Collins, K, Feigon, J. | | 登録日 | 2010-05-25 | | 公開日 | 2010-06-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Effect of pseudouridylation on the structure and activity of the catalytically essential P6.1 hairpin in human telomerase RNA.
Nucleic Acids Res., 38, 2010
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2KWB
 | | Minimal Constraint Solution NMR Structure of Translationally-controlled tumor protein (TCTP) from C.elegans, Northeast Structural Genomics Consortium Target WR73 | | 分子名称: | Translationally-controlled tumor protein homolog | | 著者 | Aramini, J.M, Rossi, P, Cort, J.R, Cooper, B, Maglaqui, M, Janjua, H, Xiao, R, Acton, T.B, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2010-04-02 | | 公開日 | 2010-04-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Minimal Constraint Solution NMR Structure of Translationally-controlled tumor protein (TCTP) from C.elegans, Northeast Structural Genomics Consortium Target WR73
To be Published
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3P1I
 | | Ligand binding domain of human ephrin type-B receptor 3 | | 分子名称: | CHLORIDE ION, Ephrin type-B receptor 3, SULFATE ION | | 著者 | Walker, J.R, Yermekbayeva, L, Seitova, A, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2010-09-30 | | 公開日 | 2011-01-19 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Ligand Binding Domain of Human Ephb3
To be Published
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2KKN
 | | Solution NMR structure of Themotoga maritima protein TM1076: Northeast Structural Genomics Consortium target VT57 | | 分子名称: | Uncharacterized protein | | 著者 | Cort, J.R, Yee, A, Garcia, M, Isern, N.G, Arrowsmith, C.H, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2009-06-26 | | 公開日 | 2009-10-06 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR structure of Themotoga maritima protein TM1076
To be Published
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2KJ9
 | | NMR structure of IntB phage-integrase-like protein fragment 90-199 from Erwinia carotova subsp. atroseptica: Northeast Structural Genomics Consortium target EwR217E | | 分子名称: | Integrase | | 著者 | Cort, J.R, Ramelot, T.A, Wang, D, Ciccosanti, C, Janjua, H, Nair, R, Rost, B, Swapna, G, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2009-05-25 | | 公開日 | 2009-07-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of IntB phage-integrase-like protein fragment 90-199 from Erwinia carotova subsp. atroseptica
To be Published
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2KYI
 | | Solution NMR structure of Dsy0195(21-82) protein from Desulfitobacterium Hafniense. Northeast Structural Genomics Consortium Target DhR8C | | 分子名称: | Uncharacterized protein | | 著者 | Yang, Y, Ramelot, T.A, Cort, J.R, Wang, H, Ciccosanti, C, Foote, E.L, Jiang, M, Janjua, H, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2010-05-27 | | 公開日 | 2010-06-09 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Combining NMR and EPR methods for homodimer protein structure determination.
J.Am.Chem.Soc., 132, 2010
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2K8S
 | | Solution NMR structure of dimeric thioredoxin-like protein NE0084 from Nitrosomonas europea: Northeast Structural Genomics Target NeT6 | | 分子名称: | Thioredoxin | | 著者 | Cort, J.R, Ramelot, T.A, Yee, A, Arrowsmith, C.H, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2008-09-23 | | 公開日 | 2008-12-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR structure of dimeric thioredoxin-like protein NE0084 from Nitrosomonas europea: Northeast Structural Genomics Target NeT6
To be Published
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2KKM
 | | Solution NMR structure of yeast protein YOR252W [residues 38-178]: Northeast Structural Genomics Consortium target YT654 | | 分子名称: | Translation machinery-associated protein 16 | | 著者 | Cort, J.R, Yee, A, Liu, C, Arrowsmith, C.H, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2009-06-26 | | 公開日 | 2009-10-06 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR structure of yeast protein YOR252W
To be Published
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2KRS
 | | Solution NMR structure of SH3 domain from CPF_0587 (fragment 415-479) from Clostridium perfringens. Northeast Structural Genomics Consortium (NESG) Target CpR74A. | | 分子名称: | Probable enterotoxin | | 著者 | Ramelot, T.A, Cort, J.R, Maglaqui, M, Ciccosanti, C, Janjua, H, Nair, R, Rost, B, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2009-12-22 | | 公開日 | 2010-01-26 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR structure of SH3 domain from CPF_0587 (fragment 415-479) from Clostridium perfringens. Northeast Structural Genomics Consortium (NESG) Target CpR74A.
To be Published
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7R6R
 | | Crystal Structure of a Mycobacteriophage Cluster A2 Immunity Repressor:DNA Complex | | 分子名称: | DNA (5'-D(P*CP*CP*CP*GP*CP*TP*TP*GP*AP*CP*AP*GP*CP*CP*AP*CP*CP*GP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*CP*GP*GP*TP*GP*GP*CP*TP*GP*TP*CP*AP*AP*GP*CP*GP*GP*G)-3'), Immunity repressor | | 著者 | McGinnis, R.J, Brambley, C.A, Stamey, B, Green, W.C, Gragg, K.N, Cafferty, E.R, Terwilliger, T.C, Hammel, M, Hollis, T.J, Miller, J.M, Gainey, M.D, Wallen, J.R. | | 登録日 | 2021-06-23 | | 公開日 | 2022-07-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.13 Å) | | 主引用文献 | A monomeric mycobacteriophage immunity repressor utilizes two domains to recognize an asymmetric DNA sequence.
Nat Commun, 13, 2022
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2L8P
 | | Solution Structure of a DNA Duplex Containing the Potent Anti-Poxvirus Agent Cidofovir | | 分子名称: | DNA (5'-D(*CP*GP*CP*AP*TP*GP*(L8P)P*TP*AP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*TP*AP*GP*CP*AP*TP*GP*CP*G)-3') | | 著者 | Julien, O, Beadle, J.R, Magee, W.C, Chatterjee, S, Hostetler, K.Y, Evans, D.H, Sykes, B.D. | | 登録日 | 2011-01-22 | | 公開日 | 2011-02-23 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a DNA duplex containing the potent anti-poxvirus agent cidofovir.
J.Am.Chem.Soc., 133, 2011
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2L8T
 | | Staphylococcus aureus pathogenicity island 1 protein gp6, an internal scaffold in size determination | | 分子名称: | Transposon Tn557 toxic shock syndrome toxin-1 | | 著者 | Dearborn, A.D, Spilman, M.S, Damle, P.K, Chang, J.R, Monroe, E.B, Saad, J.S, Christie, G.E, Dokland, T. | | 登録日 | 2011-01-24 | | 公開日 | 2011-08-17 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Staphylococcus aureus Pathogenicity Island 1 Protein gp6 Functions as an Internal Scaffold during Capsid Size Determination.
J.Mol.Biol., 412, 2011
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8T4N
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5HZM
 | | Human HMT1 hnRNP methyltransferase-like protein 6 (S. cerevisiae) | | 分子名称: | Protein arginine N-methyltransferase 6, S-ADENOSYL-L-HOMOCYSTEINE, UNKNOWN ATOM OR ION | | 著者 | DONG, A, ZENG, H, WALKER, J.R, Seitova, A, Hutchinson, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, MIN, J, WU, H, Structural Genomics Consortium (SGC) | | 登録日 | 2016-02-02 | | 公開日 | 2016-02-17 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Structural basis of arginine asymmetrical dimethylation by PRMT6.
Biochem. J., 473, 2016
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1BHF
 | | P56LCK SH2 DOMAIN INHIBITOR COMPLEX | | 分子名称: | INHIBITOR ACE-IPA-GLU-GLU-ILE, T-LYMPHOCYTE-SPECIFIC PROTEIN TYROSINE KINASE P56LCK | | 著者 | Tong, L, Warren, T.C, Lukas, S, Schembri-King, J, Betageri, R, Proudfoot, J.R, Jakes, S. | | 登録日 | 1998-06-08 | | 公開日 | 1998-10-21 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Carboxymethyl-phenylalanine as a replacement for phosphotyrosine in SH2 domain binding.
J.Biol.Chem., 273, 1998
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2LK2
 | | Solution NMR structure of homeobox domain (171-248) of human homeobox protein TGIF1, Northeast Structural Genomics Consortium Target HR4411B | | 分子名称: | Homeobox protein TGIF1 | | 著者 | Yang, Y, Ramelot, T.A, Cort, J.R, Shastry, R, Ciccosanti, C, Hamilton, K, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2011-09-30 | | 公開日 | 2011-10-26 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR structure of homeobox domain (171-248) of human homeobox protein TGIF1, Northeast Structural Genomics Consortium Target HR4411B.
To be Published
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8STH
 | | human STING with diABZI agonist 15 | | 分子名称: | 1-[(2E)-4-{5-carbamoyl-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-7-(3-hydroxypropoxy)-1H-benzimidazol-1-yl}but-2-en-1-yl]-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-7-methoxy-1H-benzimidazole-5-carboxamide, Stimulator of interferon genes protein | | 著者 | Duvall, J.R, Bukhalid, R.A. | | 登録日 | 2023-05-10 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Discovery and Optimization of a STING Agonist Platform for Application in Antibody Drug Conjugates.
J.Med.Chem., 66, 2023
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1BDK
 | | AN NMR, CD, MOLECULAR DYNAMICS, AND FLUOROMETRIC STUDY OF THE CONFORMATION OF THE BRADYKININ ANTAGONIST B-9340 IN WATER AND IN AQUEOUS MICELLAR SOLUTIONS | | 分子名称: | bradykinin antagonist B-9340 | | 著者 | Sejbal, J, Kotovych, G, Cann, J.R, Stewart, J.M, Gera, L. | | 登録日 | 1995-07-28 | | 公開日 | 1995-12-07 | | 最終更新日 | 2024-06-05 | | 実験手法 | SOLUTION NMR | | 主引用文献 | An NMR, CD, molecular dynamics, and fluorometric study of the conformation of the bradykinin antagonist B-9340 in water and in aqueous micellar solutions.
J.Med.Chem., 39, 1996
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