7NHC
 
 | | 1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease ordered (Class2b) | | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | | Authors: | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | | Deposit date: | 2021-02-10 | | Release date: | 2021-12-01 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.87 Å) | | Cite: | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
|
|
7NJ3
 | | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8196 core | | Descriptor: | Nanobody8196 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | | Authors: | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | | Deposit date: | 2021-02-15 | | Release date: | 2021-12-01 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (4.48 Å) | | Cite: | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
|
|
7NIL
 | | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8190 core | | Descriptor: | Nanobody8190 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | | Authors: | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | | Deposit date: | 2021-02-12 | | Release date: | 2021-12-01 | | Last modified: | 2022-02-09 | | Method: | ELECTRON MICROSCOPY (5.01 Å) | | Cite: | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
|
|
7NK8
 | | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8205 core | | Descriptor: | Nb8205, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ... | | Authors: | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | | Deposit date: | 2021-02-17 | | Release date: | 2021-12-01 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (5.34 Å) | | Cite: | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
|
|
8WJ5
 | | Double-wing domain of E. coli YdcD | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Uncharacterized protein YdcD | | Authors: | Kamata, K, Tame, J.R.H. | | Deposit date: | 2023-09-25 | | Release date: | 2024-10-02 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Making the unphasable feasible
To Be Published
|
|
4P16
 | | Crystal structure of the papain-like protease of Middle-East Respiratory Syndrome coronavirus | | Descriptor: | ORF1a, ZINC ION | | Authors: | Lei, J, Mesters, J.R, Ma, Q, Hilgenfeld, R. | | Deposit date: | 2014-02-25 | | Release date: | 2014-05-07 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of the papain-like protease of MERS coronavirus reveals unusual, potentially druggable active-site features.
Antiviral Res., 109C, 2014
|
|
7N5U
 | | ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing GGACCC (Oligo 21) | | Descriptor: | DNA Strain II, DNA Strand I, ZINC ION, ... | | Authors: | Horton, J.R, Ren, R, Cheng, X. | | Deposit date: | 2021-06-06 | | Release date: | 2022-06-08 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.86 Å) | | Cite: | Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
J.Biol.Chem., 299, 2023
|
|
7N5W
 | | ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing GGACCC (Oligo 23) | | Descriptor: | 1,2-ETHANEDIOL, DNA Strand I, DNA Strand II, ... | | Authors: | Horton, J.R, Ren, R, Cheng, X. | | Deposit date: | 2021-06-06 | | Release date: | 2022-06-08 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.24 Å) | | Cite: | Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
J.Biol.Chem., 299, 2023
|
|
7N5V
 | | ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing GGACCC (Oligo 20) | | Descriptor: | DNA Strand I, DNA Strand II, ZINC ION, ... | | Authors: | Horton, J.R, Ren, R, Cheng, X. | | Deposit date: | 2021-06-06 | | Release date: | 2022-06-08 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.08 Å) | | Cite: | Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
J.Biol.Chem., 299, 2023
|
|
4PBB
 | |
4N21
 | | Crystal structure of the GP2 Core Domain from the California Academy of Science Virus | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, GP2 Ectodomain | | Authors: | Malashkevich, V.N, Koellhoffer, J.F, Dai, Z, Toro, R, Lai, J.R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | | Deposit date: | 2013-10-04 | | Release date: | 2013-11-27 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Structural Characterization of the Glycoprotein GP2 Core Domain from the CAS Virus, a Novel Arenavirus-Like Species.
J.Mol.Biol., 426, 2014
|
|
4N4Q
 | | Crystal Structure of N-acetylneuraminate lyase from Mycoplasma synoviae, crystal form II | | Descriptor: | Acylneuraminate lyase | | Authors: | Georgescauld, F, Popova, K, Gupta, A.J, Bracher, A, Engen, J.R, Hayer-Hartl, M, Hartl, F.U. | | Deposit date: | 2013-10-08 | | Release date: | 2014-05-21 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | GroEL/ES Chaperonin Modulates the Mechanism and Accelerates the Rate of TIM-Barrel Domain Folding.
Cell(Cambridge,Mass.), 157, 2014
|
|
8XKL
 | | Structure of ACPII-CCPII from cryptophyte algae | | Descriptor: | (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E})-3,7,12,16-tetramethyl-18-[(4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-3,5,7,9,11,13,15-heptaen-1,17-diynyl]cyclohex-3-en-1-ol, (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-3,5,7,9,11,13,15,17-octaen-1-ynyl]cyclohex-3-en-1-ol, (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaen-1-ynyl]cyclohex-3-en-1-ol, ... | | Authors: | Li, X.Y, Mao, Z.Y, Shen, J.R, Han, G.Y. | | Deposit date: | 2023-12-23 | | Release date: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.84 Å) | | Cite: | Structure and distinct supramolecular organization of a PSII-ACPII dimer from a cryptophyte alga Chroomonas placoidea.
Nat Commun, 15, 2024
|
|
8Y5V
 | | GII.4 Sydney PD and 2'-FL | | Descriptor: | 1,2-ETHANEDIOL, GII.4 Sydney PD in complex with 2'-FL (powder), alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Hansman, G, Tame, J.R.H, Kher, G, Pancera, M. | | Deposit date: | 2024-02-01 | | Release date: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | GII.4 Sydney PD and 2'-FL
To Be Published
|
|
4MT0
 | |
4MZ0
 | |
8Y6C
 | | Norovirus GII.10 P domain and 2'-FL (powder) | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GII.10 norovirus P domain in complex with 2'FL (powder), ... | | Authors: | Hansman, G, Tame, J.R.H, Kher, G, Pancera, M. | | Deposit date: | 2024-02-02 | | Release date: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.47 Å) | | Cite: | Norovirus GII.10 P domain and 2'-FL (powder)
To Be Published
|
|
8Y6D
 | | Norovirus GII.10 P domain and 2'-FL (tablet) | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GII.10 norovirus P domain in complex with 2'-FL (tablet), ... | | Authors: | Hansman, G, Tame, J.R.H, Kher, G, Pancera, M. | | Deposit date: | 2024-02-02 | | Release date: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.41 Å) | | Cite: | Norovirus GII.10 P domain and 2'-FL (tablet)
To Be Published
|
|
7NT8
 | | Influenza virus H3N2 nucleoprotein - R416A mutant | | Descriptor: | Glutathione S-transferase class-mu 26 kDa isozyme,Nucleoprotein | | Authors: | Keown, J.R, Knight, M.L, Grimes, J.M, Fodor, E. | | Deposit date: | 2021-03-09 | | Release date: | 2021-07-07 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.22 Å) | | Cite: | Structure of an H3N2 influenza virus nucleoprotein.
Acta Crystallogr.,Sect.F, 77, 2021
|
|
8UWU
 | | EmrE structure in the proton-bound state (WT/L51I heterodimer) | | Descriptor: | SMR family multidrug efflux protein EmrE | | Authors: | Li, J, Sae Her, A, Besch, A, Ramirez, B, Crames, M, Banigan, J.R, Mueller, C, Marsiglia, W.M, Zhang, Y, Traaseth, N.J. | | Deposit date: | 2023-11-08 | | Release date: | 2024-05-29 | | Last modified: | 2024-07-03 | | Method: | SOLID-STATE NMR, SOLUTION NMR | | Cite: | Dynamics underlie the drug recognition mechanism by the efflux transporter EmrE.
Nat Commun, 15, 2024
|
|
4NKG
 | | Crystal structure of SspH1 LRR domain in complex PKN1 HR1b domain | | Descriptor: | E3 ubiquitin-protein ligase sspH1, HEXANE-1,6-DIOL, Serine/threonine-protein kinase N1 | | Authors: | Keszei, A.F.A, Xiaojing, T, Mccormick, C, Zeqiraj, E, Rohde, J.R, Tyers, M, Sicheri, F. | | Deposit date: | 2013-11-12 | | Release date: | 2013-12-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structure of an SspH1-PKN1 Complex Reveals the Basis for Host Substrate Recognition and Mechanism of Activation for a Bacterial E3 Ubiquitin Ligase.
Mol.Cell.Biol., 34, 2014
|
|
4NSH
 | | Carboplatin binding to HEWL in 0.2M NH4SO4, 0.1M NaAc in 25% PEG 4000 at pH 4.6 | | Descriptor: | ACETATE ION, DIMETHYL SULFOXIDE, Lysozyme C, ... | | Authors: | Tanley, S.W.M, Diederichs, K, Kroon-Batenburg, L.M.J, Levy, C, Schreurs, A.M.M, Helliwell, J.R. | | Deposit date: | 2013-11-28 | | Release date: | 2014-10-15 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Carboplatin binding to histidine.
Acta Crystallogr F Struct Biol Commun, 70, 2014
|
|
7NW3
 | | X-ray crystallographic study of PIYDIN, which contains the truncation determinants of binding PI and N, bound to RoAb13, a CCR5 antibody | | Descriptor: | Antibody RoAb13 Heavy Chain, Antibody RoAb13 Light Chain, Region from C-C chemokine receptor type 5 N-terminal domain | | Authors: | Saridakis, E, Helliwell, J.R, Govada, L, Chayen, N.E. | | Deposit date: | 2021-03-16 | | Release date: | 2021-07-21 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3.200011 Å) | | Cite: | X-ray crystallographic studies of RoAb13 bound to PIYDIN, a part of the N-terminal domain of C-C chemokine receptor 5.
Iucrj, 8, 2021
|
|
4POU
 | | VHH-metal in Complex with RNase A | | Descriptor: | Ribonuclease pancreatic, VHH Antibody | | Authors: | Fanning, S.W, Walter, R, Horn, J.R. | | Deposit date: | 2014-02-26 | | Release date: | 2014-09-24 | | Last modified: | 2014-10-22 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural basis of an engineered dual-specific antibody: conformational diversity leads to a hypervariable loop metal-binding site.
Protein Eng.Des.Sel., 27, 2014
|
|
6S5X
 | | Structure of RibR, the most N-terminal Rib domain from Group B Streptococcus species Streptococcus agalactiae | | Descriptor: | Group B streptococcal R4 surface protein, SODIUM ION | | Authors: | Whelan, F, Turkenburg, J.P, Griffiths, S.C, Bateman, A, Potts, J.R. | | Deposit date: | 2019-07-02 | | Release date: | 2019-12-11 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Defining the remarkable structural malleability of a bacterial surface protein Rib domain implicated in infection.
Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
