6P7E
 
 | | Structure of T7 DNA Polymerase Bound to a Primer/Template DNA and a Peptide that Mimics the C-terminal Tail of the Primase-Helicase | | 分子名称: | ASP-THR-ASP-PHE peptide, DNA (25-MER), DNA (5'-D(P*GP*GP*CP*AP*GP*GP*TP*GP*GP*TP*CP*TP*TP*GP*CP*CP*GP*GP*TP*GP*A)-3'), ... | | 著者 | Foster, B.M, Rosenberg, D, Salvo, H, Stephens, K.L, Bintz, B.J, Hammel, M, Ellenberger, T, Gainey, M.D, Wallen, J.R. | | 登録日 | 2019-06-05 | | 公開日 | 2020-03-04 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.001 Å) | | 主引用文献 | Combined Solution and Crystal Methods Reveal the Electrostatic Tethers That Provide a Flexible Platform for Replication Activities in the Bacteriophage T7 Replisome.
Biochemistry, 58, 2019
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6PBX
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8BI9
 | | Structure of a cyclic beta-hairpin peptide derived from neuronal nitric oxide synthase (T112W/T116E variant) | | 分子名称: | Nitric oxide synthase, brain, TERTIARY-BUTYL ALCOHOL | | 著者 | Balboa, J.R, Ostergaard, S, Stromgaard, K, Knapp, S, Joerger, A.C, Structural Genomics Consortium (SGC) | | 登録日 | 2022-11-01 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | | 主引用文献 | Development of a Potent Cyclic Peptide Inhibitor of the nNOS/PSD-95 Interaction.
J.Med.Chem., 66, 2023
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1EYU
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6XZP
 | | Influenza C virus polymerase in complex with chicken ANP32A - Subclass 4 | | 分子名称: | LRRcap domain-containing protein, Polymerase acidic protein, Polymerase basic protein 2, ... | | 著者 | Carrique, L, Keown, J.R, Fan, H, Grimes, J.M, Fodor, E. | | 登録日 | 2020-02-05 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Host ANP32A mediates the assembly of the influenza virus replicase.
Nature, 587, 2020
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8BVO
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8BW6
 | | Titin FnIII-domain I110 (I/A6) from the MIR region | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Mayans, O, Fleming, J.R. | | 登録日 | 2022-12-06 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-03-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Immunological and Structural Characterization of Titin Main Immunogenic Region; I110 Domain Is the Target of Titin Antibodies in Myasthenia Gravis.
Biomedicines, 11, 2023
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1EXN
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6PBD
 | | DNA N6-Adenine Methyltransferase CcrM In Complex with Double-Stranded DNA Oligonucleotide Containing Its Recognition Sequence GAATC | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*TP*TP*CP*AP*AP*TP*GP*AP*AP*TP*CP*CP*CP*AP*AP*G)-3'), DNA (5'-D(*GP*CP*TP*TP*GP*GP*GP*AP*TP*TP*CP*AP*TP*TP*GP*AP*AP*TP*C)-3'), ... | | 著者 | Horton, J.R, Cheng, X, Woodcock, C.B. | | 登録日 | 2019-06-13 | | 公開日 | 2019-10-23 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.343 Å) | | 主引用文献 | The cell cycle-regulated DNA adenine methyltransferase CcrM opens a bubble at its DNA recognition site.
Nat Commun, 10, 2019
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8BS7
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8BNQ
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6Y0C
 | | Influenza C virus polymerase in complex with human ANP32A - Subclass 2 | | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*GP*CP*CP*UP*UP*UP*U)-3'), ... | | 著者 | Fan, H, Carrique, L, Keown, J.R, Grimes, J.M, Fodor, E. | | 登録日 | 2020-02-07 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Host ANP32A mediates the assembly of the influenza virus replicase.
Nature, 587, 2020
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8BCK
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8BC5
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8BBT
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8BCL
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6QA2
 | | R80A MUTANT OF NUCLEOSIDE DIPHOSPHATE KINASE FROM MYCOBACTERIUM TUBERCULOSIS | | 分子名称: | Nucleoside diphosphate kinase, SULFATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE | | 著者 | Dautant, A, Henri, J, Wales, T.E, Meyer, P, Engen, J.R, Georgescauld, F. | | 登録日 | 2018-12-18 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Remodeling of the Binding Site of Nucleoside Diphosphate Kinase Revealed by X-ray Structure and H/D Exchange.
Biochemistry, 58, 2019
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6YGN
 | | Titin kinase and its flanking domains | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Titin | | 著者 | Fleming, J.R, Franke, B, Bogomolovas, J, Mayans, O. | | 登録日 | 2020-03-27 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Titin kinase ubiquitination aligns autophagy receptors with mechanical signals in the sarcomere.
Embo Rep., 22, 2021
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2XCU
 | | Membrane-embedded monofunctional glycosyltransferase WaaA of Aquifex aeolicus, complex with CMP | | 分子名称: | 3-DEOXY-D-MANNO-2-OCTULOSONIC ACID TRANSFERASE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | | 著者 | Schmidt, H, Hansen, G, Hilgenfeld, R, Mamat, U, Mesters, J.R. | | 登録日 | 2010-04-26 | | 公開日 | 2011-05-11 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | Structural and Mechanistic Analysis of the Membrane-Embedded Glycosyltransferase Waaa Required for Lipopolysaccharide Synthesis.
Proc.Natl.Acad.Sci.USA, 109, 2012
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6Z8F
 | | Human Picobirnavirus D45-CP VLP | | 分子名称: | Capsid protein precursor | | 著者 | Ortega-Esteban, A, Mata, C.P, Rodriguez-Espinosa, M.J, Luque, D, Irigoyen, N, Rodriguez, J.M, de Pablo, P.J, Caston, J.R. | | 登録日 | 2020-06-02 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Cryo-electron Microscopy Structure, Assembly, and Mechanics Show Morphogenesis and Evolution of Human Picobirnavirus.
J.Virol., 94, 2020
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6Z8D
 | | Human Picobirnavirus CP VLP | | 分子名称: | Capsid protein precursor | | 著者 | Ortega-Esteban, A, Mata, C.P, Rodriguez-Espinosa, M.J, Luque, D, Irigoyen, N, Rodriguez, J.M, de Pablo, P.J, Caston, J.R. | | 登録日 | 2020-06-02 | | 公開日 | 2020-09-23 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.63 Å) | | 主引用文献 | Cryo-electron Microscopy Structure, Assembly, and Mechanics Show Morphogenesis and Evolution of Human Picobirnavirus.
J.Virol., 94, 2020
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6X7M
 | | LnmK in complex with 2-nitronate-propionyl-oxa(dethia)-CoA | | 分子名称: | Bifunctional methylmalonyl-CoA:ACP acyltransferase/decarboxylase, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... | | 著者 | Stunkard, L.M, Kick, B.J, Lohman, J.R. | | 登録日 | 2020-05-30 | | 公開日 | 2020-06-10 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Structures of LnmK, a Bifunctional Acyltransferase/Decarboxylase, with Substrate Analogues Reveal the Basis for Selectivity and Stereospecificity.
Biochemistry, 60, 2021
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6XBS
 | | Streptomyces coelicolor methylmalonyl-CoA epimerase (E43Q) in complex with 2-nitronate-propionyl-CoA | | 分子名称: | CHLORIDE ION, COBALT (II) ION, Methylmalonyl-CoA epimerase, ... | | 著者 | Stunkard, L.M, Boram, T.J, Benjamin, A.B, Bower, J.B, Lohman, J.R. | | 登録日 | 2020-06-07 | | 公開日 | 2020-07-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Streptomyces coelicolor methylmalonyl-CoA epimerase (E43Q) in complex with 2-nitronate-propionyl-CoA
To Be Published
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6XZD
 | | Influenza C virus polymerase complex without chicken ANP32A - Subclass 2 | | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*GP*CP*CP*CP*UP*GP*C)-3'), ... | | 著者 | Keown, J.R, Carrique, L, Fan, H, Grimes, J.M, Fodor, E. | | 登録日 | 2020-02-04 | | 公開日 | 2020-12-23 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Host ANP32A mediates the assembly of the influenza virus replicase.
Nature, 587, 2020
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6BH3
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