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PDB: 680 results

6GZS
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BU of 6gzs by Molmil
Structure of Chlamydia trachomatis effector protein ChlaDUB1 bound to ubiquitin
Descriptor: Deubiquitinase and deneddylase Dub1, GLYCEROL, Polyubiquitin-B, ...
Authors:Pruneda, J.N, Komander, D.
Deposit date:2018-07-05
Release date:2018-11-14
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation.
Nat Microbiol, 3, 2018
6GZT
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BU of 6gzt by Molmil
Structure of Chlamydia trachomatis effector protein ChlaDUB1 bound to Coenzyme A
Descriptor: COENZYME A, Deubiquitinase and deneddylase Dub1, GLYCEROL, ...
Authors:Pruneda, J.N, Komander, D.
Deposit date:2018-07-05
Release date:2018-11-14
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation.
Nat Microbiol, 3, 2018
2MCG
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BU of 2mcg by Molmil
THREE-DIMENSIONAL STRUCTURE OF A LIGHT CHAIN DIMER CRYSTALLIZED IN WATER. CONFORMATIONAL FLEXIBILITY OF A MOLECULE IN TWO CRYSTAL FORMS
Descriptor: IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN)
Authors:Ely, K.R, Herron, J.N, Edmundson, A.B.
Deposit date:1989-05-09
Release date:1990-10-15
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-dimensional structure of a light chain dimer crystallized in water. Conformational flexibility of a molecule in two crystal forms.
J.Mol.Biol., 210, 1989
3AL2
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BU of 3al2 by Molmil
Crystal Structure of TopBP1 BRCT7/8
Descriptor: DNA topoisomerase 2-binding protein 1, SULFATE ION
Authors:Leung, C.C, Glover, J.N.
Deposit date:2010-07-22
Release date:2010-12-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control
J.Biol.Chem., 286, 2011
3AL3
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BU of 3al3 by Molmil
Crystal Structure of TopBP1 BRCT7/8-BACH1 peptide complex
Descriptor: DNA topoisomerase 2-binding protein 1, FORMIC ACID, Peptide of Fanconi anemia group J protein
Authors:Leung, C.C, Glover, J.N.
Deposit date:2010-07-22
Release date:2010-12-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control
J.Biol.Chem., 286, 2011
3BII
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BU of 3bii by Molmil
Crystal Structure of Activated MPT Synthase
Descriptor: CHLORIDE ION, Molybdopterin-converting factor subunit 1, Molybdopterin-converting factor subunit 2
Authors:Daniels, J.N, Schindelin, H.
Deposit date:2007-11-30
Release date:2008-02-19
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a molybdopterin synthase-precursor Z complex: insight into its sulfur transfer mechanism and its role in molybdenum cofactor deficiency.
Biochemistry, 47, 2008
1TAS
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BU of 1tas by Molmil
CRYSTALLINE MITOCHONDRIAL ASPARTATE AMINOTRANSFERASE EXISTS IN ONLY TWO CONFORMATIONS
Descriptor: 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID, ASPARTATE AMINOTRANSFERASE
Authors:Hohenester, E, Jansonius, J.N.
Deposit date:1993-10-04
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystalline mitochondrial aspartate aminotransferase exists in only two conformations.
J.Mol.Biol., 236, 1994
3CIG
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BU of 3cig by Molmil
Crystal structure of mouse TLR3 ectodomain
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Liu, L, Botos, I, Wang, Y, Leonard, J.N, Shiloach, J, Segal, D.M, Davies, D.R.
Deposit date:2008-03-11
Release date:2008-05-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Structural basis of toll-like receptor 3 signaling with double-stranded RNA.
Science, 320, 2008
3CS1
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BU of 3cs1 by Molmil
Flagellar Calcium-binding Protein (FCaBP) from T. cruzi
Descriptor: Flagellar calcium-binding protein
Authors:Ames, J.B, Ladner, J.E, Wingard, J.N, Robinson, H, Fisher, A.
Deposit date:2008-04-08
Release date:2008-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights into Membrane Targeting by the Flagellar Calcium-binding Protein (FCaBP), a Myristoylated and Palmitoylated Calcium Sensor in Trypanosoma cruzi.
J.Biol.Chem., 283, 2008
3CIY
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BU of 3ciy by Molmil
Mouse Toll-like receptor 3 ectodomain complexed with double-stranded RNA
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Liu, L, Botos, I, Wang, Y, Leonard, J.N, Shiloach, J, Segal, D.M, Davies, D.R.
Deposit date:2008-03-12
Release date:2008-05-06
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Structural basis of toll-like receptor 3 signaling with double-stranded RNA.
Science, 320, 2008
8ST7
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BU of 8st7 by Molmil
Structure of E3 ligase VsHECT bound to ubiquitin
Descriptor: E3 ubiquitin-protein ligase SopA-like catalytic domain-containing protein, Ubiquitin, prop-2-en-1-amine
Authors:Franklin, T.G, Pruneda, J.N.
Deposit date:2023-05-09
Release date:2023-07-12
Last modified:2024-01-03
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Bacterial ligases reveal fundamental principles of polyubiquitin specificity.
Mol.Cell, 83, 2023
8ST9
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BU of 8st9 by Molmil
Structure of E3 ligase NleL bound to ubiquitin
Descriptor: E3 ubiquitin-protein ligase SopA, Ubiquitin, prop-2-en-1-amine
Authors:Franklin, T.G, Pruneda, J.N.
Deposit date:2023-05-09
Release date:2023-07-12
Last modified:2024-01-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Bacterial ligases reveal fundamental principles of polyubiquitin specificity.
Mol.Cell, 83, 2023
8ST8
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BU of 8st8 by Molmil
Structure of E3 ligase SopA bound to ubiquitin
Descriptor: E3 ubiquitin-protein ligase SopA, Ubiquitin, prop-2-en-1-amine
Authors:Franklin, T.G, Pruneda, J.N.
Deposit date:2023-05-09
Release date:2023-07-12
Last modified:2024-01-03
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Bacterial ligases reveal fundamental principles of polyubiquitin specificity.
Mol.Cell, 83, 2023
5NG5
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BU of 5ng5 by Molmil
multi-drug efflux; membrane transport; RND superfamily; Drug resistance
Descriptor: 6-[2-(3,4-dimethoxyphenyl)ethylsulfanyl]-8-[4-(2-methoxyethyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile, Multidrug efflux pump accessory protein AcrZ, Multidrug efflux pump subunit AcrA, ...
Authors:Wang, Z, Fan, G, Hryc, C.F, Blaza, J.N, Serysheva, I.I, Schmid, M.F, Chiu, W, Luisi, B.F, Du, D.
Deposit date:2017-03-16
Release date:2017-04-19
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:An allosteric transport mechanism for the AcrAB-TolC Multidrug Efflux Pump.
Elife, 6, 2017
5OXI
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BU of 5oxi by Molmil
C-terminally retracted ubiquitin L67S mutant
Descriptor: SULFATE ION, Ubiquitin L67S mutant
Authors:Gladkova, C.G, Schubert, A.F, Wagstaff, J.L, Pruneda, J.N, Freund, S.M.V, Komander, D.
Deposit date:2017-09-06
Release date:2017-11-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:An invisible ubiquitin conformation is required for efficient phosphorylation by PINK1.
EMBO J., 36, 2017
5O31
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BU of 5o31 by Molmil
Mitochondrial complex I in the deactive state
Descriptor: Acyl carrier protein, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Blaza, J.N, Vinothkumar, K.R, Hirst, J.
Deposit date:2017-05-23
Release date:2018-01-17
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (4.13 Å)
Cite:Structure of the Deactive State of Mammalian Respiratory Complex I.
Structure, 26, 2018
4GSA
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BU of 4gsa by Molmil
CRYSTAL STRUCTURE OF GLUTAMATE-1-SEMIALDEHYDE AMINOMUTASE (AMINOTRANSFERASE) REDUCED WITH CYANOBOROHYDRATE
Descriptor: GLUTAMATE SEMIALDEHYDE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
Authors:Hennig, M, Jansonius, J.N.
Deposit date:1997-02-26
Release date:1998-03-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of glutamate-1-semialdehyde aminomutase: an alpha2-dimeric vitamin B6-dependent enzyme with asymmetry in structure and active site reactivity.
Proc.Natl.Acad.Sci.USA, 94, 1997
7MQ2
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BU of 7mq2 by Molmil
C9A Streptococcus pneumoniae CstR in the reduced state, space group P21
Descriptor: Copper-sensing transcriptional repressor csoR
Authors:Fakhoury, J.N, Gonzalez-Gutierrez, G, Giedroc, D.P.
Deposit date:2021-05-05
Release date:2022-03-09
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Functional asymmetry and chemical reactivity of CsoR family persulfide sensors.
Nucleic Acids Res., 49, 2021
7MQ1
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BU of 7mq1 by Molmil
C9A Streptococcus pneumoniae CstR in the reduced state, space group C2
Descriptor: CHLORIDE ION, Copper-sensing transcriptional repressor csoR, GLYCEROL, ...
Authors:Fakhoury, J.N, Gonzalez-Gutierrez, G, Giedroc, D.P.
Deposit date:2021-05-05
Release date:2022-03-09
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Functional asymmetry and chemical reactivity of CsoR family persulfide sensors.
Nucleic Acids Res., 49, 2021
4NN9
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BU of 4nn9 by Molmil
REFINED ATOMIC STRUCTURES OF N9 SUBTYPE INFLUENZA VIRUS NEURAMINIDASE AND ESCAPE MUTANTS
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NEURAMINIDASE N9, ...
Authors:Tulip, W.R, Varghese, J.N, Baker, A.T, Vandonkelaar, A, Laver, W.G, Webster, R.G, Colman, P.M.
Deposit date:1991-03-28
Release date:1992-07-15
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Refined atomic structures of N9 subtype influenza virus neuraminidase and escape mutants.
J.Mol.Biol., 221, 1991
6KL2
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BU of 6kl2 by Molmil
Structure of the N-terminal domain of Middle East respiratory syndrome coronavirus nucleocapsid protein
Descriptor: Nucleoprotein
Authors:Hou, M.H, Wang, Y.S, Lin, S.M, Hsu, J.N.
Deposit date:2019-07-29
Release date:2020-03-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Structure-Based Stabilization of Non-native Protein-Protein Interactions of Coronavirus Nucleocapsid Proteins in Antiviral Drug Design.
J.Med.Chem., 63, 2020
5T5K
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BU of 5t5k by Molmil
Structure of histone-based chromatin in Archaea
Descriptor: CACODYLATE ION, DNA (90-MER), DNA-binding protein HMf-2
Authors:Bhattacharyya, S, Mattiroli, F, Dyer, P.N, Sandman, K, Reeve, J.N, Luger, K.
Deposit date:2016-08-31
Release date:2017-08-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structure of histone-based chromatin in Archaea.
Science, 357, 2017
1NNC
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BU of 1nnc by Molmil
INFLUENZA VIRUS NEURAMINIDASE SUBTYPE N9 (TERN) COMPLEXED WITH 4-GUANIDINO-NEU5AC2EN INHIBITOR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NEURAMINIDASE N9, ...
Authors:Varghese, J.N, Colman, P.M.
Deposit date:1995-03-15
Release date:1996-04-03
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Three-dimensional structure of the complex of 4-guanidino-Neu5Ac2en and influenza virus neuraminidase.
Protein Sci., 4, 1995
6LNN
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BU of 6lnn by Molmil
Crystal structure of MERS-CoV N-NTD complexed with ligand P4-1
Descriptor: 5-propoxy-1H-indole, Nucleoprotein
Authors:Hou, M.H, Lin, S.M, Hsu, J.N.
Deposit date:2019-12-31
Release date:2021-01-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.634 Å)
Cite:Targeting the N-Terminus Domain of the Coronavirus Nucleocapsid Protein Induces Abnormal Oligomerization via Allosteric Modulation.
Front Mol Biosci, 9, 2022
6LZ6
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BU of 6lz6 by Molmil
Crystal structure of MERS-CoV N-NTD complexed with ligand P4-3
Descriptor: 5-(2-fluoranylethoxy)-1H-indole, Nucleoprotein
Authors:Hou, M.H, Lin, S.M, Hsu, J.N.
Deposit date:2020-02-18
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.646 Å)
Cite:Targeting the N-Terminus Domain of the Coronavirus Nucleocapsid Protein Induces Abnormal Oligomerization via Allosteric Modulation.
Front Mol Biosci, 9, 2022

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