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PDB: 5587 件

4DPP
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The structure of dihydrodipicolinate synthase 2 from Arabidopsis thaliana
分子名称: Dihydrodipicolinate synthase 2, chloroplastic, SODIUM ION
著者Griffin, M.D.W, Billakanti, J.M, Gerrard, J.A, Dobson, R.C.J, Pearce, F.G.
登録日2012-02-14
公開日2012-07-18
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Characterisation of the first enzymes committed to lysine biosynthesis in Arabidopsis thaliana
Plos One, 7, 2012
2A8V
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RHO TRANSCRIPTION TERMINATION FACTOR/RNA COMPLEX
分子名称: 5'-R(P*CP*CP*C)-3', 5'-R(P*CP*CP*CP*CP*CP*C)-3', RNA BINDING DOMAIN OF RHO TRANSCRIPTION TERMINATION FACTOR
著者Bogden, C.E, Fass, D, Bergman, N, Nichols, M.D, Berger, J.M.
登録日1998-11-08
公開日1999-04-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structural basis for terminator recognition by the Rho transcription termination factor.
Mol.Cell, 3, 1999
2AB5
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bI3 LAGLIDADG Maturase
分子名称: SULFATE ION, mRNA maturase
著者Longo, A, Leonard, C.W, Bassi, G.S, Berndt, D, Krahn, J.M, Hall, T.M, Weeks, K.M.
登録日2005-07-14
公開日2005-08-30
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Evolution from DNA to RNA recognition by the bI3 LAGLIDADG maturase
Nat.Struct.Mol.Biol., 12, 2005
3BVC
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Crystal structure of uncharacterized protein Ism_01780 from Roseovarius nubinhibens ISM
分子名称: CALCIUM ION, NICKEL (II) ION, Uncharacterized protein Ism_01780
著者Patskovsky, Y, Toro, R, Meyer, A.J, Rutter, M, Iizuka, M, Maletic, M, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2008-01-06
公開日2008-02-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Crystal structure of an uncharacterized protein Ism_01780 from Roseovarius nubinhibens.
To be Published
2A8H
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Crystal structure of catalytic domain of TACE with Thiomorpholine Sulfonamide Hydroxamate inhibitor
分子名称: 4-({4-[(4-AMINOBUT-2-YNYL)OXY]PHENYL}SULFONYL)-N-HYDROXY-2,2-DIMETHYLTHIOMORPHOLINE-3-CARBOXAMIDE, ADAM 17, ZINC ION
著者Levin, J.I, Chen, J.M, Laakso, L.M, Du, M, Schmid, J, Xu, W, Cummons, T, Xu, J, Jin, G, Barone, D, Skotnicki, J.S.
登録日2005-07-08
公開日2006-02-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Acetylenic TACE inhibitors. Part 3: Thiomorpholine sulfonamide hydroxamates.
Bioorg.Med.Chem.Lett., 16, 2006
4DFX
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Crystal structure of myristoylated K7C catalytic subunit of cAMP-dependent protein kinase in complex with SP20 and AMP-PNP
分子名称: GLYCEROL, MAGNESIUM ION, MYRISTIC ACID, ...
著者Bastidas, A.C, Steichen, J.M, Taylor, S.S.
登録日2012-01-24
公開日2012-06-06
最終更新日2013-01-02
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase.
J.Mol.Biol., 422, 2012
4DKQ
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Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with DMJ-I-228
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, N-[(1S,2S)-2-carbamimidamido-2,3-dihydro-1H-inden-1-yl]-N'-(4-chloro-3-fluorophenyl)ethanediamide, ...
著者Kwon, Y.D, LaLonde, J.M, Jones, D.M, Sun, A.W, Courter, J.R, Soeta, T, Kobayashi, T, Princiotto, A.M, Wu, X, Mascola, J, Schon, A, Freire, E, Sodroski, J, Madani, N, Smith III, A.B, Kwong, P.D.
登録日2012-02-03
公開日2012-05-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.888 Å)
主引用文献Structure-Based Design, Synthesis, and Characterization of Dual Hotspot Small-Molecule HIV-1 Entry Inhibitors.
J.Med.Chem., 55, 2012
3BKK
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Tesis ACE co-crystal structure with ketone ACE inhibitor kAF
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ...
著者Watermeyer, J.M, Kroger, W.L, O'Neill, H.G, Sewell, B.T, Sturrock, E.D.
登録日2007-12-07
公開日2008-06-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Probing the basis of domain-dependent inhibition using novel ketone inhibitors of Angiotensin-converting enzyme
Biochemistry, 47, 2008
3BPD
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Crystal structure of an uncharacterized protein (O28723_ARCFU) from Archaeoglobus fulgidus
分子名称: MAGNESIUM ION, Uncharacterized protein
著者Eswaramoorthy, S, Burley, S.K, Sauder, J.M, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-12-18
公開日2008-01-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of an uncharacterized protein (O28723_ARCFU) from Archaeoglobus fulgidus.
To be Published
3BQ9
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Crystal structure of predicted nucleotide-binding protein from Idiomarina baltica OS145
分子名称: GLYCEROL, Predicted Rossmann fold nucleotide-binding domain-containing protein, SULFATE ION
著者Patskovsky, Y, Toro, R, Meyer, A.J, Dickey, M, Eberle, M, Koss, J, Groshong, C, Wasserman, S.R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-12-19
公開日2008-01-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Predicted Nucleotide-Binding Protein from Idiomarina baltica.
To be Published
3BS2
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Crystal Structure of Monomine
分子名称: GLYCEROL, Lipocalin
著者Mans, B.J, Ribeiro, J.M, Andersen, J.F.
登録日2007-12-21
公開日2008-04-01
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Structure, function, and evolution of biogenic amine-binding proteins in soft ticks.
J.Biol.Chem., 283, 2008
4EDG
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BU of 4edg by Molmil
The structure of the S. aureus DnaG RNA Polymerase Domain bound to ATP and Manganese
分子名称: ADENOSINE-5'-TRIPHOSPHATE, BENZAMIDINE, DNA primase, ...
著者Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M.
登録日2012-03-27
公開日2012-07-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
1XUI
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TRYPSIN-KETO-BABIM, ZN+2-FREE, PH 8.2
分子名称: BIS(5-AMIDINO-2-BENZIMIDAZOLYL)METHANONE, CALCIUM ION, SODIUM ION, ...
著者Katz, B.A, Clark, J.M, Finer-Moore, J.S, Jenkins, T.E, Johnson, C.R, Rose, M.J, Luong, C, Moore, W.R, Stroud, R.M.
登録日1997-10-10
公開日1998-11-11
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Design of potent selective zinc-mediated serine protease inhibitors.
Nature, 391, 1998
1XUG
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TRYPSIN-BABIM-ZN+2, PH 8.2
分子名称: BIS(5-AMIDINO-BENZIMIDAZOLYL)METHANE, CALCIUM ION, TRYPSIN, ...
著者Katz, B.A, Clark, J.M, Finer-Moore, J.S, Jenkins, T.E, Johnson, C.R, Rose, M.J, Luong, C, Moore, W.R, Stroud, R.M.
登録日1997-10-10
公開日1998-12-16
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Design of potent selective zinc-mediated serine protease inhibitors.
Nature, 391, 1998
1Y8X
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Structural basis for recruitment of Ubc12 by an E2-binding domain in NEDD8's E1
分子名称: Ubiquitin-activating enzyme E1C, Ubiquitin-conjugating enzyme E2 M
著者Huang, D.T, Paydar, A, Zhuang, M, Waddell, M.B, Holton, J.M, Schulman, B.A.
登録日2004-12-13
公開日2005-02-08
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1.
Mol.Cell, 17, 2005
1Y6B
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Crystal structure of VEGFR2 in complex with a 2-anilino-5-aryl-oxazole inhibitor
分子名称: N-(CYCLOPROPYLMETHYL)-4-(METHYLOXY)-3-({5-[3-(3-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-YL}AMINO)BENZENESULFONAMIDE, Vascular endothelial growth factor receptor 2
著者Harris, P.A, Cheung, M, Hunter, R.N, Brown, M.L, Veal, J.M, Nolte, R.T, Wang, L, Liu, W, Crosby, R.M, Johnson, J.H, Epperly, A.H, Kumar, R, Luttrell, D.K, Stafford, J.A.
登録日2004-12-05
公開日2005-06-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Discovery and evaluation of 2-anilino-5-aryloxazoles as a novel class of VEGFR2 kinase inhibitors.
J.Med.Chem., 48, 2005
1Y0J
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Zinc fingers as protein recognition motifs: structural basis for the GATA-1/Friend of GATA interaction
分子名称: Erythroid transcription factor, ZINC ION, Zinc-finger protein ush
著者Liew, C.K, Simpson, R.J.Y, Kwan, A.H.Y, Crofts, L.A, Loughlin, F.E, Matthews, J.M, Crossley, M, Mackay, J.P.
登録日2004-11-15
公開日2005-01-25
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Zinc fingers as protein recognition motifs: Structural basis for the GATA-1/Friend of GATA interaction
Proc.Natl.Acad.Sci.Usa, 102, 2005
1Y2P
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Solution structure of Hstx3P
分子名称: Neurotoxin HsTX1
著者Mosbah, A, Gariga, L, Darbon, H, Sabatier, J.M.
登録日2004-11-23
公開日2005-11-01
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献The impact of the fourth disulfide bridge in scorpion toxins of the alpha-KTx6 subfamily
Proteins, 61, 2005
1ZLC
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Solution Conformation of alpha-conotoxin PIA
分子名称: Alpha-conotoxin PIA
著者Chi, S.-W, Lee, S.-H, Kim, D.-H, Kim, J.-S, Olivera, B.M, McIntosh, J.M, Han, K.-H.
登録日2005-05-05
公開日2006-05-02
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution structure of alpha-conotoxin PIA, a novel antagonist of alpha6 subunit containing nicotinic acetylcholine receptors
Biochem.Biophys.Res.Commun., 338, 2005
4EZ1
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Crystal structure of acetylcholine binding protein (AChBP) from Aplysia Californica in complex with alpha-conotoxin BuIA
分子名称: Alpha-conotoxin BuIA, MANGANESE (II) ION, Soluble acetylcholine receptor
著者Talley, T.T, Reger, A.S, Kim, C, Sankaran, B, Ho, K, Taylor, P, McIntosh, J.M.
登録日2012-05-02
公開日2013-05-08
最終更新日2013-06-19
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Pairwise interaction of alpha-conotoxin BuIA Pro6 with the beta subunit of nicotinic acetylcholine receptor
To be Published
4F09
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Discovery and Optimization of C-2 Methyl Imidazo-pyrrolopyridines as Potent and Orally Bioavailable JAK1 Inhibitors with Selectivity over JAK2
分子名称: 2-methyl-1-(piperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine, Tyrosine-protein kinase JAK2
著者Murray, J.M.
登録日2012-05-03
公開日2012-07-04
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery and Optimization of C-2 Methyl Imidazopyrrolopyridines as Potent and Orally Bioavailable JAK1 Inhibitors with Selectivity over JAK2.
J.Med.Chem., 55, 2012
4F0S
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Crystal structure of an adenosine deaminase homolog from Chromobacterium violaceum (target NYSGRC-019589) with bound inosine.
分子名称: 5-methylthioadenosine/S-adenosylhomocysteine deaminase, CHLORIDE ION, INOSINE, ...
著者Kim, J, Vetting, M.W, Sauder, J.M, Burley, S.K, Raushel, F.M, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2012-05-04
公開日2012-06-06
最終更新日2021-02-10
実験手法X-RAY DIFFRACTION (1.851 Å)
主引用文献Crystal structure of an adenosine deaminase homolog from Chromobacterium violaceum (target NYSGRC-019589) with bound inosine.
To be Published
4F37
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Structure of the tethered N-terminus of Alzheimer's disease A peptide
分子名称: Colicin-E7 immunity protein, Fab WO2 anti-amyloid-beta antibody Fab fragment, Im7 immunity protein
著者Nisbet, R.M, Nuttall, S.D, Caine, J.M, Rober, R, Hittaki, M, Pearce, L.A, Davydova, N, Masters, C.L, Varghese, J.N, Streltsov, V.A.
登録日2012-05-09
公開日2013-05-15
最終更新日2014-09-03
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Structural studies of the tethered N-terminus of the Alzheimer's disease amyloid-beta peptide.
Proteins, 81, 2013
1ZNM
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A zinc finger with an artificial beta-turn, original sequence taken from the third zinc finger domain of the human transcriptional repressor protein YY1 (YING and YANG 1, a delta transcription factor), nmr, 34 structures
分子名称: YY1, ZINC ION
著者Viles, J.H, Patel, S.U, Mitchell, J.B.O, Moody, C.M, Justice, D.E, Uppenbrink, J, Doyle, P.M, Harris, C.J, Sadler, P.J, Thornton, J.M.
登録日1997-11-20
公開日1998-04-01
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Design, synthesis and structure of a zinc finger with an artificial beta-turn.
J.Mol.Biol., 279, 1998
1YVC
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Solution structure of the conserved protein from the gene locus MMP0076 of Methanococcus maripaludis. Northeast Structural Genomics target MrR5.
分子名称: MrR5
著者Northeast Structural Genomics Consortium (NESG), Rossi, P, Aramini, J.M, Xiao, R, Ho, C.K, Ma, L.C, Acton, T.B, Montelione, G.T.
登録日2005-02-15
公開日2005-04-05
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献
To be Published

222624

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