3BD6
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![BU of 3bd6 by Molmil](/molmil-images/mine/3bd6) | Glycogen Phosphorylase complex with 1(-D-ribofuranosyl) cyanuric acid | Descriptor: | 1-beta-D-ribofuranosyl-1,3,5-triazinane-2,4,6-trione, Glycogen phosphorylase, muscle form | Authors: | Sovantzis, D.A, Hadjiloi, T, Hayes, J.M, Zographos, S.E, Chrysina, E.D, Oikonomakos, N.G. | Deposit date: | 2007-11-14 | Release date: | 2008-11-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | D-Glucopyranosyl pyrimidine nucleoside binding to muscle glycogen phosphorylase b To be Published
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2G9Z
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![BU of 2g9z by Molmil](/molmil-images/mine/2g9z) | Thiamin pyrophosphokinase from Candida albicans | Descriptor: | 3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-5-(2-{[HYDROXY(PHOSPHONOAMINO)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-I UM, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Abergel, C, Santini, S, Monchois, V, Rousselle, T, Claverie, J.M, Bacterial targets at IGS-CNRS, France (BIGS) | Deposit date: | 2006-03-07 | Release date: | 2006-04-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Structural characterization of CA1462, the Candida albicans thiamine pyrophosphokinase. Bmc Struct.Biol., 8, 2008
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2GC1
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![BU of 2gc1 by Molmil](/molmil-images/mine/2gc1) | |
1RZT
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![BU of 1rzt by Molmil](/molmil-images/mine/1rzt) | Crystal structure of DNA polymerase lambda complexed with a two nucleotide gap DNA molecule | Descriptor: | 1,2-ETHANEDIOL, 5'-D(*CP*GP*GP*CP*AP*AP*CP*GP*CP*AP*C)-3', 5'-D(*GP*TP*GP*CP*G)-3', ... | Authors: | Pedersen, L.C, Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Blanco, L, Kunkel, T.A. | Deposit date: | 2003-12-29 | Release date: | 2004-03-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A structural solution for the DNA polymerase lambda-dependent repair of DNA gaps with minimal homology. Mol.Cell, 13, 2004
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3R4G
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![BU of 3r4g by Molmil](/molmil-images/mine/3r4g) | Human Cyclophilin D Complexed with a Fragment | Descriptor: | 4-sulfamoylbenzoic acid, GLYCEROL, Peptidyl-prolyl cis-trans isomerase F, ... | Authors: | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | Deposit date: | 2011-03-17 | Release date: | 2012-03-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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3MZN
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![BU of 3mzn by Molmil](/molmil-images/mine/3mzn) | Crystal structure of probable glucarate dehydratase from chromohalobacter salexigens dsm 3043 | Descriptor: | ACETATE ION, GLYCEROL, Glucarate dehydratase, ... | Authors: | Patskovsky, Y, Toro, R, Rutter, M, Sauder, J.M, Gerlt, J.A, Almo, S.C, Burley, S.K, New York Structural GenomiX Research Consortium (NYSGXRC), New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2010-05-12 | Release date: | 2010-05-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal Structure of Glucarate Dehydratase from Chromohalobacter Salexigens To be Published
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3R57
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![BU of 3r57 by Molmil](/molmil-images/mine/3r57) | Human Cyclophilin D Complexed with a Fragment | Descriptor: | GLYCEROL, N-(3-aminophenyl)acetamide, Peptidyl-prolyl cis-trans isomerase F, ... | Authors: | Colliandre, L, Ahmed-Belkacem, H, Bessin, Y, Pawlotsky, J.M, Guichou, J.F. | Deposit date: | 2011-03-18 | Release date: | 2012-03-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
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1SC4
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![BU of 1sc4 by Molmil](/molmil-images/mine/1sc4) | |
3N1F
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![BU of 3n1f by Molmil](/molmil-images/mine/3n1f) | Crystal Structure of IhhN bound to CDOFn3 | Descriptor: | CALCIUM ION, Cell adhesion molecule-related/down-regulated by oncogenes, Indian hedgehog protein, ... | Authors: | Kavran, J.M, Leahy, D.J. | Deposit date: | 2010-05-15 | Release date: | 2010-06-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner. J.Biol.Chem., 285, 2010
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3N28
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![BU of 3n28 by Molmil](/molmil-images/mine/3n28) | Crystal structure of probable phosphoserine phosphatase from vibrio cholerae, unliganded form | Descriptor: | Phosphoserine phosphatase, SULFATE ION | Authors: | Patskovsky, Y, Ramagopal, U, Toro, R, Rutter, M, Miller, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2010-05-17 | Release date: | 2010-07-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of Phosphoserine Phosphatase from Vibrio Cholerae To be Published
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3B2N
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![BU of 3b2n by Molmil](/molmil-images/mine/3b2n) | Crystal structure of DNA-binding response regulator, LuxR family, from Staphylococcus aureus | Descriptor: | SODIUM ION, Uncharacterized protein Q99UF4 | Authors: | Malashkevich, V.N, Toro, R, Meyer, A.J, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-10-18 | Release date: | 2007-10-30 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Crystal structure of DNA-binding response regulator, LuxR family, from Staphylococcus aureus. To be Published
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4A8W
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![BU of 4a8w by Molmil](/molmil-images/mine/4a8w) | Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation | Descriptor: | 5'-D(*TP*TP*CP*GP*CP*GP*TP*AP*AP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. | Deposit date: | 2011-11-21 | Release date: | 2012-07-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.04 Å) | Cite: | Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
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3N1M
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![BU of 3n1m by Molmil](/molmil-images/mine/3n1m) | Crystal Structure of IhhN bound to BOCFn3 | Descriptor: | Brother of CDO, CALCIUM ION, Indian hedgehog protein, ... | Authors: | Kavran, J.M, Leahy, D.J. | Deposit date: | 2010-05-15 | Release date: | 2010-06-02 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner. J.Biol.Chem., 285, 2010
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3HII
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![BU of 3hii by Molmil](/molmil-images/mine/3hii) | |
3HL7
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![BU of 3hl7 by Molmil](/molmil-images/mine/3hl7) | Crystal Structure of Human p38alpha complexed with SD-0006 | Descriptor: | 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine, 2-{4-[5-(4-chlorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-3-yl]piperidin-1-yl}-2-oxoethanol, Mitogen-activated protein kinase 14 | Authors: | Shieh, H.-S, Kurumbail, R.G, Stegeman, R.A, Williams, J.M. | Deposit date: | 2009-05-26 | Release date: | 2009-07-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Structural bioinformatics-based prediction of exceptional selectivity of p38 MAP kinase inhibitor PH-797804. Biochemistry, 48, 2009
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4D0O
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![BU of 4d0o by Molmil](/molmil-images/mine/4d0o) | AKAP13 (AKAP-Lbc) DH domain | Descriptor: | A-KINASE ANCHOR PROTEIN 13 | Authors: | Abdul Azeez, K.R, Shrestha, L, Krojer, T, Allerston, C, von Delft, F, Bountra, C, Arrowsmith, C, Edwards, A.M, Knapp, S, Klussmann, E, Elkins, J.M. | Deposit date: | 2014-04-29 | Release date: | 2014-05-21 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | The Crystal Structure of the Rhoa : Akap-Lbc Dh-Ph Domain Complex. Biochem.J., 464, 2014
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4D8L
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![BU of 4d8l by Molmil](/molmil-images/mine/4d8l) | Crystal structure of the 2-pyrone-4,6-dicarboxylic acid hydrolase from sphingomonas paucimobilis | Descriptor: | 2-pyrone-4,6-dicarbaxylate hydrolase | Authors: | Malashkevich, V.N, Toro, R, Bonanno, J, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2012-01-10 | Release date: | 2012-01-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and Catalytic Mechanism of LigI: Insight into the Amidohydrolase Enzymes of cog3618 and Lignin Degradation. Biochemistry, 51, 2012
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1N3K
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![BU of 1n3k by Molmil](/molmil-images/mine/1n3k) | Solution structure of phosphoprotein enriched in astrocytes 15 kDa (PEA-15) | Descriptor: | Astrocytic phosphoprotein PEA-15 | Authors: | Hill, J.M, Vaidyanathan, H, Ramos, J.W, Ginsberg, M.H, Werner, M.H. | Deposit date: | 2002-10-28 | Release date: | 2003-01-14 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Recognition of ERK MAP Kinase by PEA-15 Reveals a Common Docking Site Within the Death Domain and Death Effector Domain Embo J., 21, 2002
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1PQR
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![BU of 1pqr by Molmil](/molmil-images/mine/1pqr) | Solution Conformation of alphaA-Conotoxin EIVA | Descriptor: | Alpha-A-conotoxin EIVA | Authors: | Chi, S.-W, Park, K.-H, Suk, J.-E, Olivera, B.M, McIntosh, J.M, Han, K.-H. | Deposit date: | 2003-06-18 | Release date: | 2003-11-04 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Solution Conformation of alphaA-conotoxin EIVA, a Potent Neuromuscular Nicotinic Acetylcholine Receptor Antagonist from Conus ermineus J.Biol.Chem., 278, 2003
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3MOG
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![BU of 3mog by Molmil](/molmil-images/mine/3mog) | Crystal structure of 3-hydroxybutyryl-CoA dehydrogenase from Escherichia coli K12 substr. MG1655 | Descriptor: | CHLORIDE ION, GLYCEROL, Probable 3-hydroxybutyryl-CoA dehydrogenase | Authors: | Patskovsky, Y, Ramagopal, U, Toro, R, Gilmore, M, Miller, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2010-04-22 | Release date: | 2010-06-23 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of 3-Hydroxybutyryl-Coa Dehydrogenase from Escherichia Coli K12 To be Published
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4CR3
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![BU of 4cr3 by Molmil](/molmil-images/mine/4cr3) | Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome | Descriptor: | 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ... | Authors: | Unverdorben, P, Beck, F, Sledz, P, Schweitzer, A, Pfeifer, G, Plitzko, J.M, Baumeister, W, Foerster, F. | Deposit date: | 2014-02-25 | Release date: | 2014-04-02 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9.3 Å) | Cite: | Deep Classification of a Large Cryo-Em Dataset Defines the Conformational Landscape of the 26S Proteasome. Proc.Natl.Acad.Sci.USA, 111, 2014
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4D0Z
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![BU of 4d0z by Molmil](/molmil-images/mine/4d0z) | GalNAc-T2 crystal soaked with UDP-5SGalNAc, mEA2 and manganese (Higher resolution dataset) | Descriptor: | (2R,3R,4R,5R,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-5-thio-alpha-D-galactopyranose, ... | Authors: | Lira-Navarrete, E, Iglesias-Fernandez, J, Zandberg, W.F, Companon, I, Kong, Y, Corzana, F, Pinto, B.M, Clausen, H, Peregrina, J.M, Vocadlo, D, Rovira, C, Hurtado-Guerrero, R. | Deposit date: | 2014-04-30 | Release date: | 2014-05-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Substrate-Guided Front-Face Reaction Revealed by Combined Structural Snapshots and Metadynamics for the Polypeptide N- Acetylgalactosaminyltransferase 2. Angew.Chem.Int.Ed.Engl., 53, 2014
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3I6V
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![BU of 3i6v by Molmil](/molmil-images/mine/3i6v) | Crystal structure of a periplasmic His/Glu/Gln/Arg/opine family-binding protein from Silicibacter pomeroyi in complex with lysine | Descriptor: | GLYCEROL, LYSINE, SODIUM ION, ... | Authors: | Bonanno, J.B, Rutter, M, Bain, K.T, Miller, S, Romero, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2009-07-07 | Release date: | 2009-07-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a periplasmic His/Glu/Gln/Arg/opine family-binding protein from Silicibacter pomeroyi in complex with lysine To be Published
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3BG2
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![BU of 3bg2 by Molmil](/molmil-images/mine/3bg2) | Crystal structure of deoxyguanosinetriphosphate triphosphohydrolase from Flavobacterium sp. MED217 | Descriptor: | DGTP triphosphohydrolase | Authors: | Fedorov, A.A, Fedorov, E.V, Toro, R, Meyer, A.J, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-11-25 | Release date: | 2007-12-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of the deoxyguanosinetriphosphate triphosphohydrolase from Flavobacterium sp. MED217. To be Published
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3BGF
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![BU of 3bgf by Molmil](/molmil-images/mine/3bgf) | |